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Methylthioadenosine (MTA) boosts cell‐specific productivities of Chinese hamster ovary cultures: dosage effects on proli
Two scale‐down tools for the optimization of perfusion bioreactors for the manufacture of biopharmaceuticals
Valeric acid induces cell cycle arrest at G1 phase in CHO cell cultures and improves recombinant antibody productivity.
Real‐time monitoring of specific oxygen uptake rates of embryonic stem cells in a microfluidic cell culture device
Bioprocessing of Recombinant CHO-K1, CHO-DG44, and CHO-S: CHO Expression Hosts Favor Either mAb Production or Biomass Sy
High Cell Density Perfusion Culture has a Maintained Exoproteome and Metabolome
Transcriptome Analysis of CHO Cell Size Increase During a Fed-Batch Process
Combining Butyrated ManNAc with Glycoengineered CHO Cells Improves EPO Glycan Quality and Production.
Multi-Omics Study on the Impact of Cysteine Feed Level on Cell Viability and mAb Production in a CHO Bioprocess.
Replacement of Isoleucine and Leucine by their Keto Acids leads to increased formation of α-Hydroxy Acids in Chinese Ham
Bip inducer X: an ER stress inhibitor for enhancing recombinant antibody production in CHO cell culture.
Multi-Omics Reveals Impact of Cysteine Feed Concentration and Resulting Redox Imbalance on Cellular Energy Metabolism an
Modeling the Effect of Amino Acids and Copper on Monoclonal Antibody Productivity and Glycosylation: A Modular Approach.
Continuous optical in‐line glucose monitoring and control in CHO cultures contributes to enhanced metabolic efficiency w
Capillary and microchip electrophoresis method development for amino acid monitoring during biopharmaceutical cultivatio
Real‐time amino acid and glucose monitoring system for the automatic control of nutrient feeding in CHO cell culture usi
High cysteine concentrations in cell culture media lead to oxidative stress and reduced bioprocess performance of recomb
Advancing Raman model calibration for perfusion bioprocesses using spiked harvest libraries
Cottonseed hydrolysate supplementation alters metabolic and proteomics responses in Chinese hamster ovary cell cultures
Increased recombinant adeno‐associated virus production by HEK293 cells using small molecule chemical additives
NAD+ supplementation improves mAb productivity in CHO cells via a glucose metabolic shift
Raman-controlled pyruvate feeding to control metabolic activity and product quality in continuous biomanufacturing.
Rosmarinic acid enhances CHO cell productivity and proliferation through activation of the unfolded protein response and
Characterization of the Ubiquitin-Modified Proteome of Recombinant Chinese Hamster Ovary Cells in Response to Endoplasmi
Model‐based investigation of intracellular processes determining antibody Fc‐glycosylation under mild hypothermia
Whole‐cell <i>Escherichia coli</i> lactate biosensor for monitoring mammalian cell cultures during biopharmaceutical pro
Identification and control of novel growth inhibitors in fed-batch cultures of Chinese hamster ovary cells.
Overexpression of the regulatory subunit of glutamate-cysteine ligase enhances monoclonal antibody production in CHO cel
Intracellular response to process optimization and impact on productivity and product aggregates for a high‐titer CHO ce
Butyrated ManNAc analog improves protein expression in Chinese hamster ovary cells.
Process development for the continuous production of heterologous proteins by the industrial yeast, Komagataella phaffii
Impact of cell culture media additives on IgG glycosylation produced in Chinese hamster ovary cells
Process‐induced cell cycle oscillations in CHO cultures: Online monitoring and model‐based investigation
Oxidative stress‐alleviating strategies to improve recombinant protein production in CHO cells
A dynamic model linking cell growth to intracellular metabolism and extracellular by‐product accumulation
Amino acid supplementation for enhancing recombinant protein production in E. coli.
Characterization of glutathione proteome in CHO cells and its relationship with productivity and cholesterol synthesis
Cysteine in cell culture media induces acidic IgG1 species by disrupting the disulfide bond network
Application of metabolic modeling for targeted optimization of high seeding density processes
Autophagy-inducing peptide increases CHO cell monoclonal antibody production in batch and fed-batch cultures.
Media on‐demand: Continuous reconstitution of a chemically defined media directly from solids
Process intensification to produce a difficult-to-express therapeutic enzyme by high cell density perfusion or enhanced
Production of butyrate and branched-chain amino acid catabolic byproducts by CHO cells in fed-batch culture enhances the
A comparative analysis of recombinant Fab and full‐length antibody production in Chinese hamster ovary cells
Modular development enables rapid design of media for alternative hosts
Metabolic analysis of the asparagine and glutamine dynamics in an industrial Chinese hamster ovary fed‐batch process
Combined gene and environmental engineering offers a synergetic strategy to enhance r-protein production in Chinese hams
Soft-sensors application for automated feeding control in high-throughput mammalian cell cultures.
“Organized stress” for robust scale‐up of intensified production process with fed‐batch seed bioreactor
Optimization of medium with perfusion microbioreactors for high density CHO cell cultures at very low renewal rate aided
Addressing amino acid‐derived inhibitory metabolites and enhancing CHO cell culture performance through DOE‐guided media
Chemical inhibitors of hexokinase‐2 enzyme reduce lactate accumulation, alter glycosylation processing, and produce alte
CHOmpact: A reduced metabolic model of Chinese hamster ovary cells with enhanced interpretability
Harnessing metabolic plasticity in CHO cells for enhanced perfusion cultivation
Metabolomic characterization of monoclonal antibody-producing Chinese hamster lung (CHL)-YN cells in glucose-controlled
Flux Sampling Suggests Metabolic Signatures of High Antibody-Producing CHO Cells.
LC-HRMS-based targeted metabolomics for high-throughput and quantitative analysis of 21 growth inhibition-related metabo
Chemically defined media modifications to lower tryptophan oxidation of biopharmaceuticals.
Controlling the time evolution of mAb N-linked glycosylation, Part I: Microbioreactor experiments.
Effect of amino acid supplementation on titer and glycosylation distribution in hybridoma cell cultures—Systems biology‐
Antioxidant effect of thiazolidine molecules in cell culture media improves stability and performance.
Principles and approach to developing mammalian cell culture media for high cell density perfusion process leveraging es
Characterization of mammalian cell culture raw materials by combining spectroscopy and chemometrics
Impact of media and antifoam selection on monoclonal antibody production and quality using a high throughput micro‐biore
Concomitant reduction of lactate and ammonia accumulation in fed-batch cultures: Impact on glycoprotein production and q
Metabolic responses and pathway changes of mammalian cells under different culture conditions with media supplementation
Effect of cell culture medium additives on color and acidic charge variants of a monoclonal antibody.
Process development for an inducible rituximab-expressing Chinese hamster ovary cell line.
Real‐time quantification and supplementation of bioreactor amino acids to prolong culture time and maintain antibody pro
Multivariate data analysis of growth medium trends affecting antibody glycosylation
Rapid development of clone‐specific, high‐performing perfusion media from established feed supplements
Effects of cysteine, asparagine, or glutamine limitations in Chinese hamster ovary cell batch and fed-batch cultures.
The effect of amino acid supplementation in an industrial Chinese Hamster Ovary process.
Raman‐based dynamic feeding strategies using real‐time glucose concentration monitoring system during adalimumab produci
Tuning monoclonal antibody galactosylation using Raman spectroscopy-controlled lactic acid feeding.
Characterization of soy protein hydrolysates and influence of its iron content on monoclonal antibody production by a mu
Impact of iron raw materials and their impurities on CHO metabolism and recombinant protein product quality
Preventing pyruvate kinase muscle expression in Chinese hamster ovary cells curbs lactogenic behavior by altering glycol
Modulation of nutrient precursors for controlling metabolic inhibitors by genome-scale flux balance analysis.
Use of single analytic tool to quantify both absolute N‐glycosylation and glycan distribution in monoclonal antibodies
An automated high inoculation density fed‐batch bioreactor, enabled through N‐1 perfusion, accommodates clonal diversity
Multivariate data analysis of process parameters affecting the growth and productivity of stable Chinese hamster ovary c
Strategies to improve CHO cell culture performance: Targeted deletion of amino acid catabolism and apoptosis genes paire
CHO stable pool fed-batch process development of SARS-CoV-2 spike protein production: Impact of aeration conditions and
A statistical approach to improve compound screening in cell culture media
High cell density transient transfection of CHO cells for TGF‐β1 expression
Increased MSX level improves biological productivity and production stability in multiple recombinant GS CHO cell lines
Stress‐induced increase of monoclonal antibody production in CHO cells
Exploitation of the ribosomal protein L10 R98S mutation to enhance recombinant protein production in mammalian cells
Optimization of a mAb production process with regard to robustness and product quality using quality by design principle
<i>Pichia pastoris</i>: A highly successful expression system for optimal synthesis of heterologous proteins
High Nutritional Conditions Influence Feeding Plasticity in Pristionchus pacificus and Render Worms Non-Predatory.
Cellular and molecular outcomes of glutamine supplementation in the brain of succinic semialdehyde dehydrogenase-deficie
Protective role of l‐threonine against cadmium toxicity in Saccharomyces cerevisiae
Influences of Short-Term Fasting and Carbohydrate Supplementation on Gut Immunity and Mucosal Morphology in Mice.
Dietary stevioside supplementation increases feed intake by altering the hypothalamic transcriptome profile and gut micr
Supplementation of sulfur and folic acid improves performance of broiler chicken fed suboptimal concentrations of dietar
Folate deficiency and over-supplementation causes impaired folate metabolism: Regulation and adaptation mechanisms in Ca
Genome‐scale metabolic models applied for human health and biopharmaceutical engineering
Animal‐cell culture media: History, characteristics, and current issues
Effects of Dietary Supplementation of Coenzyme Q10 on Growth Performance, Biochemical and Physiological Attributes of Ra
Feeding strategy impacts heterologous protein production in Yarrowia lipolytica fed-batch cultures-Insight into the role
Insight into the roles of tyrosine on rCHO cell performance in fed-batch cultures.
Investigation into the impact of tyrosine on the product formation and quality attributes of mAbs in rCHO cell cultures.
Progress in fed-batch culture for recombinant protein production in CHO cells
Enhanced production of recombinant proteins by a small molecule protein synthesis enhancer in combination with an antiox
All-trans retinoic acid in combination with sodium butyrate enhances specific monoclonal antibody productivity in recomb
Feedback control of two supplemental feeds during fed-batch culture on a platform process using inline Raman models for
Automated Raman feed-back control of multiple supplemental feeds to enable an intensified high inoculation density fed-b
Mechanistic insights into sodium citrate-induced metabolic rewiring for enhanced S-adenosylmethionine synthesis via tran
Possible fetal bovine serum-reduced boost cultivation of DF-1 by supplementation with plant peptones and yeast extracts
First record of geophagy in Jungle Babbler (Turdoides striata) prior to egg-laying: an instinct for calcium supplement.
Development of a chemically defined platform fed-batch culture media for monoclonal antibody-producing CHO cell lines wi
Combination of temperature shift and hydrolysate addition regulates anti-IgE monoclonal antibody charge heterogeneity in
Improvement of growth rates through nucleoside media supplementation of CHO clones
Dietary indispensable amino acids profile affects protein utilization and growth of Senegalese sole larvae.
Effect of N-acetyl cysteine and glycine supplementation on growth performance, glutathione synthesis, and antioxidative
The study of ameliorative effect of dietary supplementation of vitamin C, vitamin E, and tryptophan on Labeo rohita (Cyp
Dietary cobalt supplementation improves growth and body composition and induces the expression of growth and stress resp
Dietary creatine and guanidinoacetic acid supplementation have limited effects on hybrid striped bass.
EPA and DHA promote cell proliferation and enhance activity of the Akt-TOR-S6K anabolic signaling pathway in primary mus
Dietary propylene glycol mitigates cold stress and improves physio-metabolic responses in Pangasianodon hypophthalmus (S
Effects of monensin feeding on performance, nutrient utilisation and enteric methane production in growing buffalo heife
Interaction of supplementary L-carnitine and dietary energy levels on feed utilization and blood constituents in New Zea
Identification of milk-related genes and regulatory networks in Bactrian camel either supplemented or under grazing.
Dietary supplementation with curcumin nanomicelles, curcumin, and turmeric affects growth performance and silver nanopar
Effects of Organic Selenium Supplementation on Growth, Accumulation, Haematology and Histopathology of Juvenile Barramun
Dietary Chromium Picolinate Supplementation Affects Growth, Whole-Body Composition, and Gene Expression Related to Gluco
Leucine supplementation at the onset of high-fat feeding does not prevent weight gain or improve glycemic regulation in
Dietary guanidinoacetic acid supplementation improves water holding capacity and lowers free amino acid concentration of
Dietary ribose supplementation improves flesh quality through purine metabolism in gibel carp (Carassius auratus gibelio
Effects of dietary supplementation of Bacillus subtilis DSM 32315 on growth, immune response and acute ammonia stress to
Epigallocatechin-3-gallate supplementation regulates glucose redistribution through its potential endogenous receptor in
Dietary supplementation of selenium nanoparticle improves the vitellogenesis and fecundity of female zebrafish.
Effects of bioprocessed soybean meal and nucleotide supplementation on growth, physiology and histomorphology in largemo
Effects of vitamin A supplementation on ovarian development of Astyanax lacustris (Teleostei: Characidae) during the non
Protective effects of dietary icariin on lipopolysaccharide-induced acute oxidative stress and hepatopancreas injury in
A Markov model of glycosylation elucidates isozyme specificity and glycosyltransferase interactions for glycoengineering
Effect of organic selenium dietary supplementation on quality and fertility of cryopreserved chicken sperm.
Evaluating dynamic effects of dietary glycerol monolaurate on the productive performance and flesh quality of large yell
Influence of dietary resveratrol supplementation on integrity and colloidal characteristics of Myofibrillar proteins in
Effects of Ala-Gln feeding strategies on growth, metabolism, and crowding stress resistance of juvenile Cyprinus carpio
Effect of N-acetyl cysteine and glycine supplementation on growth performance, glutathione synthesis, anti-oxidative and
Effect of dietary supplementation with apple cider vinegar and propionic acid on hemolymph chemistry, intestinal microbi
Enzyme-treated soy protein supplementation in low protein diet enhanced immune function of immune organs in on-growing g
Dietary taurine modulates hepatic oxidative status, ER stress and inflammation in juvenile turbot (Scophthalmus maximus
Modulation of growth performance, gut microflora, non-specific immunity and gene expression of proinflammatory cytokines
Administration of EPA improves lipopolysaccharide-induced intestinal dysfunction in turbot (Scophthalmus maximus L.) thr
Sulforaphane attenuates HFD-induced enteritis in yellow river carp by restoring immune homeostasis, repairing intestinal
Nitrogen supplementation ameliorates product quality and quantity during high cell density bioreactor studies of Pichia
High glucose enhances cAMP level and extracellular signal-regulated kinase phosphorylation in Chinese hamster ovary cell
Enhanced antibody production in Chinese hamster ovary cell cultures supplemented with barley shochu distillation by-prod
S-Sulfocysteine simplifies fed-batch processes and increases the CHO specific productivity via anti-oxidant activity.
Differential expression of microRNAs in recombinant Chinese hamster ovary cells treated with sodium butyrate using digit
Assessment of fed-batch cultivation strategies for an inducible CHO cell line.
Influence of media composition on recombinant monoclonal IgA1 glycosylation analysed by lectin-based protein microarray
Use of novel cystine analogs to decrease oxidative stress and control product quality.
S-Sulfocysteine - Investigation of cellular uptake in CHO cells.
A novel dynamic flux balance analysis for modeling CHO cell fed-batch cultures with pH and temperature shifts.
Beyond tyrosine feeding: A novel fed-batch cultivation strategy based on tyrosine metabolic engineering in recombinant C
Effects of Feeding Coenzyme Q10-Ubiquinol on Plasma Coenzyme Q10 Concentrations and Semen Quality in Stallions.
Effects of a high cholesterol diet on chill tolerance are highly context-dependent in Drosophila.
Identification of novel inhibitory metabolites and impact verification on growth and protein synthesis in mammalian cell
Effects of an herbal adaptogen feed-additive on feeding-related hypothalamic neuropeptides in chronic cyclic heat-stress
Kinetic modeling: A tool for temperature shift and feeding optimization in cell culture process development.
Self-control design reveals varied lactation and metabolic responses to rumen-protected methionine in dairy cows
Feeding practices and animal-level factors associated with daily milk yield in lactating smallholder dairy cows in Kiamb
Xylanase supplementation of pelleted wheat-based diets increases growth efficiency and apparent metabolizable energy and
Phytase supplementation in sorghum-based diet enhances nutrient digestibility, energy utilization, and antioxidant statu
Immune response, productivity and quality of milk from grazing goats as affected by dietary polyunsaturated fatty acid s
Genome-scale functional genomics screening highlights genes impacting protein fucosylation in Chinese hamster ovary cell
Predictive macroscopic modeling of cell growth, metabolism and monoclonal antibody production: Case study of a CHO fed-b
Expression in CHO cells of a bacterial biosynthetic pathway producing a small non-ribosomal peptide aldehyde prevents pr
Metabolic engineering of CHO cells towards cysteine prototrophy and systems analysis of the ensuing phenotype.
Ala-Cys-Cys-Ala dipeptide dimer alleviates problematic cysteine and cystine levels in media formulations and enhances CH
DL-methionyl-DL-methionine as an efficient methionine source for promoting zootechnical performance and methionine-relat
Effects of intravenous arginine infusion on inflammation and metabolic indices of dairy cows in early lactation.
Relation between feeding behaviour and energy metabolism in pigs fed diets enriched in dietary fibre and wheat aleurone.
The effect of supplementing pony diets with yeast on 2. The faecal microbiome.
Impact of Nitrogen Addition on Wine Fermentation by S. cerevisiae Strains with Different Nitrogen Requirements.
Poria cocos Polysaccharide Delays Aging by Enhancing the Antioxidant Ability and Suppressing the Expression of the Branc
Oleanolic Acid Regulates Intestinal Cell Proliferation and Protein Synthesis Capacity in Piglets via the Bile Acid-TGR5/
Supplementation with Major Royal-Jelly Proteins Increases Lifespan, Feeding, and Fecundity in Drosophila.
Sestrin2 Negatively Regulates Casein Synthesis through the SH3BP4-mTORC1 Pathway in Response to AA Depletion or Suppleme
Compartmentalized Proteomic Profiling Outlines the Crucial Role of the Classical Secretory Pathway during Recombinant Pr
Evaluation of artificial signal peptides for secretion of two lysosomal enzymes in CHO cells
Metabolic engineering of CHO cells to prepare glycoproteins.
3 Modulation of glycolysis alters histone acetylation and gene expression in bovine blastocysts produced invitro
Deciphering the determinants of recombinant protein expression across the human secretome.
Amino Acid Transport Associated to Cluster of Differentiation 98 Heavy Chain (CD98hc) Is at the Cross-road of Oxidative
Effects of trehalose supplementation on the growth performance and intestinal innate immunity of juvenile chicks.
Effects of methionine and guanidinoacetic acid supplementation on performance and energy metabolites in breast muscle of
Effects of cottonseed meal bioactive peptides on growth performance, ileal digestibility, serum amino acid and immune re
Amino acid nutrition and chicken gut health
Effect of three probiotic Bacillus strains supplemented feeds on growth, carcass composition and blood parameters of Cla
Dietary Sodium Butyrate Supplementation Promotes Oxidative Fiber Formation in Mice.
Effect of food supplementation on in vitro embryo production and growth performance in prepubertal Nelore heifers.
Using chemical chaperones to increase recombinant human erythropoietin secretion in CHO cell line.
Optimization of parameters affecting on CHO cell culture producing recombinant erythropoietin.
Impact of S-sulfocysteine on fragments and trisulfide bond linkages in monoclonal antibodies.
Nutrient supplementation strategy improves cell concentration and longevity, monoclonal antibody production and lactate
Methionine Metabolism Alters Oxidative Stress Resistance via the Pentose Phosphate Pathway
Valine increases milk fat synthesis in mammary gland of gilts through stimulating AKT/MTOR/SREBP1 pathway†
199 Supplemental arginine affects intestinal gene expression and serum concentration of amino acids of heat stress pigs
67 Effect of Different Dietary Protein Sources on Skeletal Muscle Growth Characteristics and Satellite Cell Mitotic Acti
Dietary supplementation with lysine (protein) in late pregnancy does not enhance mammary development in multiparous sows
48 The impact of leucine supplementation in milk replacer on muscle proteome and metabolism in neonatal dairy calves
45 Opportunity with functional role of supplemental amino acids
402 Awardee Talk - Efficiency of nutrient use in ruminants: Current understanding and emerging questions
Rapid metabolic regulation of a novel arginine methylation of KCa3.1 attenuates 1 T cell exhaustion 2257
A Chronic Fetal Leucine Infusion Potentiates Fetal Insulin Secretion and Increases Pancreatic Islet Size, Vascularity, a
Fine-Tuning of Postprandial Responses via Feeding Frequency and Leucine Supplementation Affects Dietary Performance in T
Impact of probiotic Bacillus sp. dietary supplementation on pancreatic and intestinal activities in seabream Sparus aura
Effects of encapsulated cinnamaldehyde on growth performance, intestinal digestive and absorptive functions, meat qualit
Evaluation of dietary arginine supplementation to increase placental nutrient transporters in aged mares
Impact of maternal antioxidant supplementation on ovarian development in prepuberal Iberian pig offspring.
Citrulline production and protein homeostasis.
Diets derived from maize monoculture cause maternal infanticides in the endangered European hamster due to a vitamin B3
Influence of ammonia and lysine supplementation on yeast growth and fermentation with respect to gluten‐free type brewin
Effects of dietary hydrolysate supplementation on growth, body composition, hematological responses, and liver histology
Effects of dietary serine addition to a high plant protein diet on growth performance, body composition, hepatosomatic h
Identification of octopus peptide and its promotion of β-casein synthesis in a mouse mammary epithelial cell line.
Impact of dietary Lactobacillus supplementation on intramuscular fat deposition and meat quality of Sunit sheep.
Iron supplementation in the diets of hybrid catfish (Ictalurus punctatus × I. furcatus) juveniles affected haematocrit l
Effects of fat supplementation on plasma glucose, insulin and fatty acid analysis in ponies maintained on a forage-based
Positive effects of dietary supplementation of three probiotics on milk yield, milk composition and intestinal flora in
Growth Performance and Microbial Activity Positively Responded to Interactive Effect of Nitrogen and Phosphorus in Young
Mineral nutrition and bone health in salmonids
A paternal diet for offspring success?
Genetic mechanisms underlying feed utilization and implementation of genomic selection for improved feed efficiency in d
Arginine Relieves the Inflammatory Response and Enhances the Casein Expression in Bovine Mammary Epithelial Cells Induce
Glutamine Metabolism Is Essential for Stemness of Bone Marrow Mesenchymal Stem Cells and Bone Homeostasis
Dietary Supplementation of L-Arginine and N-Carbamylglutamate Attenuated the Hepatic Inflammatory Response and Apoptosis
Evaluation of the Role of Soybean Lecithin, Egg Yolk Lecithin, and Krill Oil in Promoting Ovarian Development in the Fem
Dietary Supplementation with Chromium DL-Methionine Enhances Growth Performance of African Catfish (Clarias gariepinus).
Evaluation of Dietary Essential Amino Acid Supplementation on Growth, Digestive Capacity, Antioxidant, and Intestine Hea
Betaine Supplementation Into High-Carbohydrate Diets Improves Feed Efficiency and Liver Health of Megalobrama amblycepha
Effects of Glutamine Supplementation on Atlantic Salmon Salmo salar Metabolic Performance at High Temperatures.
Alanyl‐Glutamine Attenuates Soybean Meal‐Induced Intestinal Dysfunction and Growth Retardation in Largemouth Bass (Micro
Branched-Chain Amino Acids Target miR-203a/fosb Axis to Promote Skeletal Muscle Growth in Common Carp (Cyprinus carpio)
Restoring In Vivo-Like Membrane Lipidomics Promotes Exosome Trophic Behavior from Human Placental Mesenchymal Stromal/St
A natural bioactive feed additive alters expression of genes involved in inflammation in whole blood of healthy Angus he
Optimization of recombinant antibody production based on the vector design and the level of metabolites for generation o
Expression of Human Erythropoietin Containing 2 Additional N-Link in CHO-K1 Cells under Different Culture Conditions
Leucine can modulate the expression of proteins related to protein degradation signalling under mTOR inhibition in C2C12
Diffusion and Inhibition Processes in a Hollow-fiber Membrane Bioreactor for Hybridoma Culture. Development of a Mathema
Methionine and Glycine Stabilize Mitochondrial Activity in Sake Yeast During Ethanol Fermentation
Metabolic Network Modelling of Chinese Hamster Ovary (CHO) Culture Bioreactors Operated as Microbial Cell Factories
Multi-omics analysis of Chinese hamster ovary cell-based biopharmaceutical production processes
FACTORS AFFECTING CHINESE HAMSTER OVARY CELL PROLIFERATION AND VIABILITY
Data-driven modeling of the degradation of recombinant proteins in Chinese hamster ovary cells
Comparative effect of methionine and cysteine supplementation on growth performance and blood profile of Desi chicks
Effect of Supplementation of Various Sources of Methionine on Nutrient Digestibility and Intestinal Morphometry in Broil
Development of an Animal-Derived Component-Free Medium for Spodoptera frugiperda (Sf9) Cells Using Response Surface Meth
Updated transient gene expression protocol and the development of a small-scale transient gene expression protocol -eval
Effects of dietary N-carbamylglutamate supplementation on milk production performance, nutrient digestibility and blood
Translational landscape and protein biogenesis demands of the early secretory pathway in Komagataella phaffii
Enhancement of adalimumab expression in CHO cells by antioxidant small molecule additives and the underlying mechanism
Amino acid feeding reduces ammonia production through rearrangement of metabolic fluxes in central carbon metabolism of
Mitochondrial Hyperfusion Via Metabolic Sensing of Regulatory Amino Acids
Towards the development of automated fed-batch cell culture processes at microscale.
Role of lipoic acid (Thioctic acid) in improving vitality of different tissue culture cells
Regulatory Role, Mechanism, and Metabolic Profile of BIOTIN in Gene Expression
Autophagy-inducing Peptide Increases CHO Cell Monoclonal Antibody Production in Batch and Fed-batch Cultures
Lactate Control Enhances Growth Advantage in Fed-batch Cultures of Metabolically Engineered CHO Cells with Reduced Novel
Modular development enables rapid design of media for alternative hosts
Using MVDA with Stoichiometric Balances to Optimize Amino Acid Concentrations in Chemically Defined CHO Cell Culture Med
Intracellular CHO cell metabolite profiling and in vivo monitoring of redox state unravel the effect of temperature down
Uncovering new poloxamer attributes significantly impacting mammalian cell growth performance
Increased recombinant AAV production by HEK293 cells using small molecule chemical additives
Transcriptomic signature of high dietary organic selenium supplementation in sheep: A nutrigenomic insight using a custo
TRIENNIAL REPRODUCTION SYMPOSIUM: Beef heifer development and lifetime productivity in rangeland-based production system
- **DOI:** 10.25687/1996-6733.prodanimbiol.2018.3.65-74 - **Authors:** Макар З.Н., Черепанов Г.Г. - **Year:** 2018 - **J
Characterization of Chinese Hamster Ovary Cell Performance with Pentanoic Acid and N-Acetyl Cysteine Treatment
Safety and efficacy of l‐arginine produced by fermentation using Corynebacterium glutamicum KCCM 10741P for all animal s
Evaluation of feed strategy for high quality biosimilar IgG production in CHO cell fed-batch process
Combination of histidine, lysine, methionine, and leucine promotes β-casein synthesis via the mechanistic target of rapa
Analysis of pasture supplementation strategies by means of a mechanistic model of ruminal digestion and metabolism in th
Increasing the availability of threonine, isoleucine, valine, and leucine relative to lysine while maintaining an ideal
Methionine and valine activate the mammalian target of rapamycin complex 1 pathway through heterodimeric amino acid tast
Nutrient-sensing kinase signaling in bovine immune cells is altered during the postpartum nutrient deficit: A possible r
Seryl-tRNA synthetase-mediated essential amino acids regulate β-casein synthesis via cell proliferation and mammalian ta
Effects of selenium supplementation on chemical composition and aromatic profiles of cow milk and its derived cheese.
Effects of dietary deoiled soy lecithin supplementation on milk production and fatty acid digestibility in Holstein dair
Effect of dietary supplementation or cessation of magnesium-based alkalizers on milk fat output in dairy cows under milk
Effects of branched-chain amino acids on glucose uptake and lactose synthesis rates in bovine mammary epithelial cells a
Effects of hydrogen peroxide and l-tryptophan on antioxidative potential, apoptosis, and mammalian target of rapamycin s
Effects of feeding difructose anhydride on the mineral status and milking performance of transition cows.
Impacts of feeding milk replacer supplemented with increasing concentrations of choline on feed intake, growth, and scou
Methionine metabolism and the effectiveness of its use as a feed additive
Аrginine – biological role, biosynthesis and whey consumption
Mammalian Cell Line Development Platform for Recombinant Protein Production: Expanding the Protein Expression Toolbox fo
Dietary zinc source impacts intestinal morphology and oxidative stress in young broilers
Effect of dietary N-carbamylglutamate on development of ovarian follicles via enhanced angiogenesis in the chicken.
Effects of Dietary Supplementation of Lauric Acid on Lactation Function, Mammary Gland Development, and Serum Lipid Meta
Arginine Supply Impacts the Expression of Candidate microRNA Controlling Milk Casein Yield in Bovine Mammary Tissue
Performance and Milk Composition of Nubian Goats as Affected by Increasing Level of Nannochloropsis oculata Microalgae.
Dietary Histidine, Threonine, or Taurine Supplementation Affects Gilthead Seabream (Sparus aurata) Immune Status.
Amino Acid Metabolomic Profiles in Bovine Mammary Epithelial Cells under Essential Amino Acid Restriction
Effects of L-Histidine and Sodium Acetate on β-Casein Expression in Nutrient-Restricted Bovine Mammary Epithelial Cells
Transcriptome Adaptation of the Ovine Mammary Gland to Dietary Supplementation of Extruded Linseed.
Successful Inclusion of High Vegetable Protein Sources in Feed for Rainbow Trout without Decrement in Intestinal Health
Too Much of a Good Thing: Rethinking Feed Formulation and Feeding Practices for Zinc in Swine Diets to Achieve One Healt
Effects of Dietary Glycine Supplementation on Growth Performance, Immunological, and Erythrocyte Antioxidant Parameters
Effects of Protein Supplementation Strategy and Genotype on Milk Production and Nitrogen Utilisation Efficiency in Late-
Dietary Supplementation with Linseed Oil Ethyl Esters Improves Sexual Behavior and Chosen Seminal Parameters in Porcine
Utilization of Cottonseed Meal Protein Hydrolysate by Crustaceans: Insights on Growth Performance, Protein Turnover, and
Dietary L-Lysine Requirement of Coho Salmon (Oncorhynchus kisutch) Alevins
Supplementation of Foals with a Saccharomyces cerevisiae Fermentation Product Alters the Early Response to Vaccination.
Supplementation of Methionine Dipeptide Enhances the Milking Performance of Lactating Dairy Cows
Quantitative Proteomics Revealed the Molecular Regulatory Network of Lysine and the Effects of Lysine Supplementation on
Controlling the Glycosylation Profile in mAbs Using Time-Dependent Media Supplementation.
Long-Term Feeding with Curcumin Affects the Growth, Antioxidant Capacity, Immune Status, Tissue Histoarchitecture, Immun
Effects of Dietary Inosine 5'-Monophosphate Supplementation on the Growth Performance and Salinity and Oxidative St
Potential Applications of Yeast Biomass Derived from Small-Scale Breweries
Deciphering Metabolic Pathways in High-Seeding-Density Fed-Batch Processes for Monoclonal Antibody Production: A Computa
Metabolic Control in Mammalian Fed-Batch Cell Cultures for Reduced Lactic Acid Accumulation and Improved Process Robustn
Advances in Escherichia coli-Based Therapeutic Protein Expression: Mammalian Conversion, Continuous Manufacturing, and C
Dietary Tryptophan Plays a Role as an Anti-Inflammatory Agent in European Seabass (Dicentrarchus labrax) Juveniles durin
Dietary Methionine Supplementation Improves Rainbow Trout (Oncorhynchus mykiss) Immune Responses Against Viral Haemorrha
Mouse WIF1 Is Only Modified with O-Fucose in Its EGF-like Domain III Despite Two Evolutionarily Conserved Consensus Site
Polyamines Counteract Carbonate-Driven Proteasome Stalling in Alkaline Conditions
Leucine-Rich Diet Modulates the Metabolomic and Proteomic Profile of Skeletal Muscle during Cancer Cachexia
Affecting HEK293 Cell Growth and Production Performance by Modifying the Expression of Specific Genes
Dietary Supplementation of a Mixture of Nucleotides, β-Glucan and Vitamins C and E Improved the Growth and Health Perfor
Dietary Whey Protein Supplementation Increases Immunoglobulin G Production by Affecting Helper T Cell Populations after
Transcriptome Analysis Suggests Dietary Tributyrin Enhances Feeding Intensity via Modulating Steroid Biosynthesis in Man
Methods for Using Small Non-Coding RNAs to Improve Recombinant Protein Expression in Mammalian Cells
Influence of Amino Acid Feeding on Production of Calcimycin and Analogs in Streptomyces chartreusis.
Studies to Prevent Degradation of Recombinant Fc-Fusion Protein Expressed in Mammalian Cell Line and Protein Characteriz
A Simple Method to Reduce both Lactic Acid and Ammonium Production in Industrial Animal Cell Culture
Computer-Aided Strategies for Determining the Amino Acid Composition of Medium for Chinese Hamster Ovary Cell-Based Biom
Effects of Tyrosine and Tryptophan in Rats with Diet-Induced Obesity
Are the Main Methionine Sources Equivalent? A Focus on DL-Methionine and DL-Methionine Hydroxy Analog Reveals Difference
Integrated Transcriptomic Analyses of Liver and Mammary Gland Tissues Reveals the Regulatory Mechanism Underlying Dairy
Cysteine Attenuates Intestinal Inflammation by Regulating the Gut Microbiota and TLR4-JNK/MAPK-NF-κB Pathway in Piglets
Dietary Sodium Butyrate Supplementation Enhances Silkworm Silk Yield by Simultaneously Promoting Larval Growth and Silk
Effect of Supplementing Lysine and Isoleucine as Limiting Amino Acids on Growth Performance and Amino Acid Deposition of
Using Metabolomics to Identify Cell Line-Independent Indicators of Growth Inhibition for Chinese Hamster Ovary Cell-base
A Metabolomics Approach to Increasing Chinese Hamster Ovary (CHO) Cell Productivity
Monitoring Intracellular Metabolite Dynamics in Saccharomyces cerevisiae during Industrially Relevant Famine Stimuli
Integrated Serum Metabolome and Gut Microbiome to Decipher Chicken Amino Acid Improvements Induced by Medium-Chain Monog
Enhancing Metabolism and Milk Production Performance in Periparturient Dairy Cattle through Rumen-Protected Methionine a
The Various Roles of Fatty Acids
Carnitine in Human Muscle Bioenergetics: Can Carnitine Supplementation Improve Physical Exercise?
High-Throughput Screening Identifies Two Novel Small Molecule Enhancers of Recombinant Protein Expression
Physiological Functions of Threonine in Animals: Beyond Nutrition Metabolism
Effects of Supplementation of Branched-Chain Amino Acids to Reduced-Protein Diet on Skeletal Muscle Protein Synthesis an
Choline Supplementation Normalizes Fetal Adiposity and Reduces Lipogenic Gene Expression in a Mouse Model of Maternal Ob
Production of a Dulaglutide Analogue by Apoptosis-Resistant Chinese Hamster Ovary Cells in a 3-Week Fed-Batch Process.
Towards Autonomous Process Control—Digital Twin for CHO Cell-Based Antibody Manufacturing Using a Dynamic Metabolic Mode
Glycosylation Flux Analysis of Immunoglobulin G in Chinese Hamster Ovary Perfusion Cell Culture
Accelerating Biologics Manufacturing by Upstream Process Modelling
Single-Use Printed Biosensor for L-Lactate and Its Application in Bioprocess Monitoring
Fecal Microbiota and Performance of Dairy Cattle from a West Mexican Family Dairy Farm Supplemented with a Fiber-Degradi
COMPREHENSIVE EVALUATION OF EXPRESSION PLATFORM: CHERRY PICKING THE ‘RIGHT’ TO ACCOMPLISH THE ‘BEST
Purification and Analytics of a Monoclonal Antibody from Chinese Hamster Ovary Cells Using an Automated Microbioreactor
Overexpression of G6PDH does not affect the behavior of HEK-293 clones stably expressing interferon-α2b
Leucine and Mammalian Target of Rapamycin-Dependent Activation of Muscle Protein Synthesis in Aging.
The biological role of chromium is the rationale, experience and prospects of its application to cattle
Metabolic status, reproductive, and productive performances of transition dairy cows as affected by dietary rumen-protec
Potential of growth factors and steroid hormones from cell cultures to improve in vitro fertilization in bovine
Conformational Bias in 2'-Selenium-Modified Nucleosides and the Effect on Helical Structure and Extracellular Recom
Decoding Complexity in Metabolic Networks using Integrated Mechanistic and Machine Learning Approaches
Effect of in ovo Feeding of Graded Levels of L-glutamine on Blood Biochemistry, Colour and Texture of Selected Muscles,
Amélioration de la production et de la qualité des protéines thérapeutiques recombinantes produites en culture en mode c
Characterisation of the Scs system that confers copper tolerance in Salmonella enterica serovar Typhimurium
Correlation and Predictive Modeling of Extracellular Cell Culture Metabolites to Drug Product Titer and Cellular Viabili
Development and application of quantitative liquid chromatography – mass spectrometry techniques to facilitate enhanced
Development of Saccharomyces cerevisiae as a recombinant antibody factory
Engineering Oxidative Stress Resistance in CHO Cell Factories
Evaluation of Cellular Mechanisms Involved in Recombinant Antibody Expression in Transiently Transfected Chinese Hamster
High-Throughput Platform Development for Chinese Hamster Ovary (CHO) Cell Culture Performance Enhancement Using Small Mo
Lipopolysaccharide Induces The Production Of Diagnostic Monoclonal Antibody By Hybridoma Cells Against Congenital Adrena
Effects of peptone on hybridoma growth and monoclona ! antibody formation
Partial Characterization of Yeast Hydrolysates for Insights on Chemically Defined Media for Sf-9 Insect Cells
Profiling the dynamic changes in the phosphoproteome of Chinese hamster ovary cells
Supplementation Strategies for Tuning Glycosylation of Monoclonal Antibodies and Enhancing Growth in Mammalian Cell Cult
Therapeutic modulation of Alzheimer’s disease with biological (HUCBS) and pharmacological (LISPRO) approaches
Combination of strong anion exchange liquid chromatography with microchip capillary electrophoresis sodium dodecyl sulfa
A control strategy to investigate the relationship between specific productivity and high-mannose glycoforms in CHO cell
Metabolic characterization of a CHO cell size increase phase in fed-batch cultures.
Exploring metabolic effects of dipeptide feed media on CHO cell cultures by in silico model-guided flux analysis
Enhancing the productivity and proliferation of CHO-K1 cells by oncoprotein YAP (Yes-associated protein)
Explainable AI for CHO cell culture media optimization and prediction of critical quality attribute
Characterization and design of dipeptide media formulation for scalable therapeutic production.
N-Glycosylation modulators for targeted manipulation of glycosylation for monoclonal antibodies
Model-assisted DoE software: optimization of growth and biocatalysis in Saccharomyces cerevisiae bioprocesses
Compartment-specific metabolome labeling enables the identification of subcellular fluxes that may serve as promising me
Culture media selection and feeding strategy for high titer production of a lentiviral vector by stable producer clones
Genome-scale modeling of Chinese hamster ovary cells by hybrid semi-parametric flux balance analysis
Enhancement of recombinant human IL-24 (rhIL-24) protein production from site-specific integrated engineered CHO cells b
Impact of fed-batch process intensification on the productivity and product quality of two CHO cell lines expressing uni
Amino acids in the cultivation of mammalian cells
Selection of chemically defined media for CHO cell fed-batch culture processes
Evaluating the impact of media and feed combinations on CHO cell culture performance and monoclonal antibody (trastuzuma
Effect of dietary selenium on postprandial protein deposition in the muscle of juvenile rainbow trout (Oncorhynchus myki
Glutamine supplementation moderately affects growth, plasma metabolite and free amino acid patterns in neonatal low birt
A dynamic pathway analysis approach reveals a limiting futile cycle in N-acetylglucosamine overproducing Bacillus subtil
A guide to 13C metabolic flux analysis for the cancer biologist
Genome-scale reconstructions of the mammalian secretory pathway predict metabolic costs and limitations of protein secre
Employing active learning in the optimization of culture medium for mammalian cells
Human Sialidase Neu3 is S-Acylated and Behaves Like an Integral Membrane Protein
Addition of a histone deacetylase inhibitor increases recombinant protein expression in Medicago truncatula cell culture
Application of maltose as energy source in protein-free CHO-K1 culture to improve the production of recombinant monoclon
Effect of cereal soaking and carbohydrase supplementation on growth, nutrient digestibility and intestinal microbiota in
Improved performance of a rainbow trout selected strain is associated with protein digestion rates and synchronization o
Developing a medium combination to attain similar glycosylation profile to originator by DoE and cluster analysis method
Serum-free cultures of C2C12 cells show different muscle phenotypes which can be estimated by metabolic profiling
Development of serum-free and grain-derived-nutrient-free medium using microalga-derived nutrients and mammalian cell-se
Engineering of Chinese hamster ovary cells for co-overexpressing MYC and XBP1s increased cell proliferation and recombin
Cold atmospheric plasma treatment enhances recombinant model protein production in yeast Pichia pastoris
Streamlined identification of strain engineering targets for bioprocess improvement using metabolic pathway enrichment a
Viable cell density as an indicator for dynamic feeding strategy in fed-batch and perfusion CHO cell culture.
Coagulation factor IX analysis in bioreactor cell culture supernatant predicts quality of the purified product
Discovery of l-threonine transaldolases for enhanced biosynthesis of beta-hydroxylated amino acids
Stochastic biological system-of-systems modelling for iPSC culture
Comparative Proteomics Analysis Reveals L-Arginine Activates Ethanol Degradation Pathways in HepG2 Cells
Ribosome profiling-guided depletion of an mRNA increases cell growth rate and protein secretion
Evaluation and use of disaccharides as energy source in protein-free mammalian cell cultures
Application of high EPA-producing Mortierella alpina in laying hen feed for egg DHA accumulation.
Supply of methionine and arginine alters phosphorylation of mechanistic target of rapamycin (mTOR), circadian clock prot
Dietary methionine supplementation during the estrous cycle improves follicular development and estrogen synthesis in ra
Effect of Fe2+ and Mn2+ addition on growth and β-carotene production of Dunaliella salina
Glycosylation flux analysis reveals dynamic changes of intracellular glycosylation flux distribution in Chinese hamster
Enzyme capacity-based genome scale modelling of CHO cells
Analysis of coagulation factor IX in bioreactor cell culture medium predicts yield and quality of the purified product
Essentially leading antibody production: An investigation of amino acids, myeloma and natural V-region signal peptides i
Mathematical model of the multi-amino acid multi-transporter system predicts uptake flux in CHO cells
Modular development enables rapid design of media for alternative hosts
Harnessing secretory pathway differences between HEK293 and CHO to rescue production of difficult to express proteins
Inositol depletion regulates phospholipid metabolism and activates stress signaling in HEK293T cells
Thermodynamic limitations of metabolic strategies for PHB production from formate and fructose in <i>Cupriavidus necator
A Beefy-R culture medium: replacing albumin with rapeseed protein isolates
Evaluating the potential of marine invertebrate and insect protein hydrolysates to reduce fetal bovine serum in cell cul
Employing active learning in the optimization of culture medium for mammalian cells
Development and qualification of a high-yield recombinant human Erythropoietin biosimilar
Debottlenecking and reformulating feed media for improved CHO cell growth and titer by data-driven and model-guided anal
Protein-specific signal peptides for mammalian vector engineering
Temporal Effects of Galactose and Manganese Supplementation on Monoclonal Antibody N-Linked Glycosylation in Fed-Batch a
Engineered autocrine signaling eliminates muscle cell FGF2 requirements for cultured meat production
Inferring secretory and metabolic pathway activity from omic data with secCellFie
Multi-omic characterization of antibody-producing CHO cell lines elucidates metabolic reprogramming and nutrient uptake
Evaluation of Plant- and Microbial-Derived Protein Hydrolysates as Substitutes for Fetal Bovine Serum in Cultivated Seaf
Comparing Kinetic versus Stoichiometric Priorities in Hybrid Models of CHO Metabolism
High extracellular lactate increases reductive carboxylation in breast tissue cell lines grown under normoxic conditions
Implementation of Design of Experiments (DOE) for Optimization of Feeding Strategy and Glyco-Engineering of Trastuzumab
A metabolic network-based approach for developing feeding strategies for CHO cells to increase monoclonal antibody produ
Amino Acid Requirements of the Chinese Hamster Ovary Cell Metabolism during Recombinant Protein Production
Produção do fator VII da coagulação sanguínea recombinante em células humanas
Desenvolvimento de anti-hTNF&#945; terapêutico.
Generating aldehyde-tagged antibodies with high titers and high formylglycine yields by supplementing culture media with
Stable high-level expression of factor VIII in Chinese hamster ovary cells in improved elongation factor-1 alpha-based s
Identifying model error in metabolic flux analysis – a generalized least squares approach
Dynamic genome-scale metabolic modeling of the yeast Pichia pastoris
Abstracts from the 25th European Society for Animal Cell Technology Meeting: Cell Technologies for Innovative Therapies
Abstracts from the 26th European Society for Animal Cell Technology Meeting - Cell culture technologies: bridging academ
Insights into the roles of exogenous phenylalanine and tyrosine in improving rapamycin production of Streptomyces rapamy
Characterization and optimization of mnn11Δ-mediated enhancement in heterologous protein production in Kluyveromyces mar
Experimental studies from shake flasks to 3 L stirred tank bioreactor of nutrients and oxygen supply conditions to impro
Tracking dipeptides at work-uptake and intracellular fate in CHO culture
Rich production media as a platform for CHO cell line development
SWATH-MS insights on sodium butyrate effect on mAbs production and redox homeostasis in CHO cells
The effect of the chemical chaperone 4-phenylbutyrate on secretion and activity of the p.Q160R missense variant of coagu
Regulation of amino acid transporters in the mammary gland from late pregnancy to peak lactation in the sow
Dietary supplementation with free methionine or methionine dipeptide mitigates intestinal oxidative stress induced by Ei
Exploring the effectiveness of in ovo feeding of vitamin C based on the embryonic vitamin C synthesis and absorption in
Fast exchange fluxes around the pyruvate node: a leaky cell model to explain the gain and loss of unlabelled and labelle
Responses of CHO-DHFR cells to ratio of asparagine to glutamine in feed media: cell growth, antibody production, metabol
Uridine modulates monoclonal antibody charge heterogeneity in Chinese hamster ovary cell fed-batch cultures
Cell-culture growth conditions resulting in the oxidation of a recombinant antigen-binding fragment
Bigdata analytics identifies metabolic inhibitors and promoters for productivity improvement and optimization of monoclo
Wheat gluten hydrolysates promotes fermentation performance of brewer’s yeast in very high gravity worts
Applications and analysis of hydrolysates in animal cell culture
Fast and long-lasting immune response to S-trimer COVID-19 vaccine adjuvanted by PIKA
Lysine and Leucine Deficiencies Affect Myocytes Development and IGF Signaling in Gilthead Sea Bream (Sparus aurata)
Availability of Amino Acids Extends Chronological Lifespan by Suppressing Hyper-Acidification of the Environment in Sacc
Maltose-Binding Protein (MBP), a Secretion-Enhancing Tag for Mammalian Protein Expression Systems
Metabolic engineering of CHO cells for the development of a robust protein production platform
Stable isotopes in tissues discriminate the diet of free-living wild boar from different areas of central Italy.
Use of real-time cellular analysis and Plackett-Burman design to develop the serum-free media for PC-3 prostate cancer c
Comparison of secretory signal peptides for heterologous protein expression in microalgae: Expanding the secretion portf
Mild hypothermia upregulates myc and xbp1s expression and improves anti-TNFα production in CHO cells
High glucose and low specific cell growth but not mild hypothermia improve specific r-protein productivity in chemostat
Therapeutic Fc fusion protein misfolding: A three-phasic cultivation experimental design
Evidence for co-translational misincorporation of non-canonical amino acid hydroxyproline in recombinant antibodies prod
Effects of dietary supplementation with histidine and β-alanine on blood plasma metabolome of broiler chickens at differ
Enhanced recombinant protein production in CHO cell continuous cultures under growth-inhibiting conditions is associated
Supplementing dairy feed by dicalcium phosphate and effect on dry matter intake, digestibility, milk composition, and bl
Fermented Goat Milk Supplementation in Rats Hypercholesterolmic on Malonyldialdehyde and Description of Liver Histopatho
Development of a serum free medium for HUMIRA <sup>®</sup> biosimilar by design of experiment approaches
Use of different concentrations of enzymesporin probiotic in feeding of growing young pigs
Process transfer and optimization of Chinese hamster ovary cell cultivation for monoclonal antibody production
Optimization of transient protein production by chemically transfected CHO suspension cells
Apparent nutrient digestibility of carbohydrate (corn) in Cirrhinus mrigala under the influence of chromium chloride hex
Protein evaluation in fish: African catfish as a case study
Identification of process-relevant kinases in human amniotic production cells
Development of M³C strategies in production processes with CHO cell cultures to prevent the formation of product aggrega
Proteomics Profiling of Chimeric-Truncated Tissue Plasminogen activator Producing- Chinese Hamster Ovary Cells Cultivate
Glycosylation Flux Analysis of Immunoglobulin G in Chinese Hamster Ovary Perfusion Cell Culture
Supplementing D-Type and L-Type Methionine and Its Precursor Alters the Expression of mRNA, Proteins and Metabolites Inv
Supplementing L-Isoleucine Increases Medium Protein and Alters the Expression of Genes and Proteins Involved in Milk Pro
Deciphering Metabolic Pathways in High Seeding Density Fed-Batch Processes for Monoclonal Antibody Production: A Computa
Effect of dietary tryptophan supplementation on growth, body composition and digestive enzymes activity of juvenile silv
Rich production media as a platform for CHO cell line development
Dietary Prebiotics and Probiotics Influence the Growth Performance, Feed Utilisation, and Body Indices of Snakehead (Cha
Chinese Hamster Ovary Cell Line Development via Imaging Flow Cytometry and Directed Evolution
The Epigenetic Regulation of Blinatumomab Gene Expression: Tumor Cell-dependent T cell Response against Lymphoma Cells a
A CRISPR-HITI strategy approach to improve CHO cell viability by modifying the 3'UTR of Caspase 8 Associated Protei
Regulation of urea cycle related enzymes in response to freezing in the wood frog, Rana sylvatica
Effects of dietary lysine levels on jejunal expression of amino
Dietary Taurine Improves The Growth Performance, Health Status and Liver Histopathology of Meagre (Argyrosomus Regius) F
Ncl1-mediated metabolic rewiring critical during metabolic stress
Ouantitative Proteomic Analysis of Cellular Responses to a Designed Amino Acid Feed in a Monoclonal Antibody Producing C
Fed-Batch Fermentation of L- Threonine by Escherichia Coli Supplemented with B-Vitamins
Effects of dietary resveratrol supplementation on digestive enzymes activities and serum biochemistry of rainbow trout (
Strategy for Developing a Stable CHO Cell Line that Produces Large Titers of Trastuzumab Antibody
Biljni proteinski hidrolizati kao dodatak medijima za uzgoj životinjskih stanica
Model Transferability and Reduced Experimental Burden in Cell Culture Process Development Facilitated by Hybrid Modeling
Enhanced l-Malic Acid Production by Aspergillus oryzae DSM 1863 Using Repeated-Batch Cultivation.
Advances of Glycometabolism Engineering in Chinese Hamster Ovary Cells
Functional Trimeric SARS-CoV-2 Envelope Protein Expressed in Stable CHO Cells
Strategies and Considerations for Improving Recombinant Antibody Production and Quality in Chinese Hamster Ovary Cells
Metabolic Engineering of Saccharomyces cerevisiae for Heterologous Carnosic Acid Production
Boosting Productivity for Advanced Biomanufacturing by Re-Using Viable Cells
Mechanistic insights into the biological activity of S-Sulfocysteine in CHO cells using a multi-omics approach
Development of a scalable single process for producing SARS-CoV-2 RBD monomer and dimer vaccine antigens
Sodium acetate increases the productivity of HEK293 cells expressing the ECD-Her1 protein in batch cultures: experimenta
Advancements in CHO metabolomics: techniques, current state and evolving methodologies
Modulating antibody N-glycosylation through feed additives using a multi-tiered approach
Genetics, environmental stress, and amino acid supplementation affect lactational performance via mTOR signaling pathway
Preclinical Immune Response and Safety Evaluation of the Protein Subunit Vaccine Nanocovax for COVID-19
DataSheet_2_Preclinical Immune Response and Safety Evaluation of the Protein Subunit Vaccine Nanocovax for COVID-19.pdf
Changes in the Intestine Microbial, Digestive, and Immune-Related Genes of Litopenaeus vannamei in Response to Dietary P
Effect of fermented heat-treated rice bran on performance and possible role of intestinal microbiota in laying hens.
The Reproduction Rate of Peptide Transporter PEPT-1 Deficient C. elegans Is Dependent on Dietary Glutamate Supply.
The Effect of Branched Chain Amino Acid Supplementation on Stroke-Related Sarcopenia.
Pea Peptide Supplementation in Conjunction With Resistance Exercise Promotes Gains in Muscle Mass and Strength
Over-expression of a Codon Optimized Yeast Cytosolic Pyruvate Carboxylase (PYC2) in CHO Cells for an Augmented Lactate M
A Guide to Transient Expression of Membrane Proteins in HEK-293 Cells for Functional Characterization
Dietary Aroclor 1254-Induced Toxicity on Antioxidant Capacity, Immunity and Energy Metabolism in Chinese Mitten Crab Eri
Effects of Dietary Inclusion of Shrimp Paste on Growth Performance, Digestive Enzymes Activities, Antioxidant and Immuno
Comparative study on the effects of crystalline L-methionine and methionine hydroxy analogue calcium supplementations in
Research progress in the role and mechanism of Leucine in regulating animal growth and development
Critical Analysis of the Commercial Potential of Plants for the Production of Recombinant Proteins
Dietary Enteromorpha Polysaccharides Supplementation Improves Breast Muscle Yield and Is Associated With Modification of
Bacillus subtilis Produces Amino Acids to Stimulate Protein Synthesis in Ruminal Tissue Explants via the Phosphatidylino
Varying the ratio of Lys: Met through enhancing methionine supplementation improved milk secretion ability through regul
Effects of lysine and threonine on milk yield, amino acid metabolism, and fecal microbiota of Yili lactating mares
Impact of Acetylated and Non-Acetylated Fucose Analogues on IgG Glycosylation
The Effect of the Expression of the Antiapoptotic BHRF1 Gene on the Metabolic Behavior of a Hybridoma Cell Line
Temperature Upshifts in Mammalian Cell Culture: A Suitable Strategy for Biosimilar Monoclonal Antibodies?
Improved Titer in Late-Stage Mammalian Cell Culture Manufacturing by Re-Cloning
Optimization and Scale-Up of Fermentation Processes Driven by Models
Hybrid Modelling and Multi- Parametric Control of Bioprocesses
Clever Experimental Designs: Shortcuts for Better iPSC Differentiation
Stability and Requirement for Thiamin in a Cell Culture Feed Used to Produce New Biological Entities
Identification of Small Molecules Affecting the Secretion of Therapeutic Antibodies with the Retention Using Selective H
High-Level Production of scFv-Fc Antibody Using an Artificial Promoter System with Transcriptional Positive Feedback Loo
Dynamics of Amino Acid Metabolism, Gene Expression, and Circulomics in a Recombinant Chinese Hamster Ovary Cell Line Ada
Identification of Cell Culture Factors Influencing Afucosylation Levels in Monoclonal Antibodies by Partial Least-Square
Dynamic Optimisation of Fed-Batch Bioreactors for mAbs: Sensitivity Analysis of Feed Nutrient Manipulation Profiles
Enhanced Production of Anti-PD1 Antibody in CHO Cells through Transient Co-Transfection with Anti-Apoptotic Gene Bcl-xL
Dynamic Optimization of a Fed-Batch Nosiheptide Reactor
Key Challenges in Designing CHO Chassis Platforms
Effect of Sialic Acid on Mammalian Cell Culture and Protein Expression: A Potential Productivity Enhancer for Biopharmac
mAb Production Modeling and Design Space Evaluation Including Glycosylation Process
Optimizing the Production of gp145, an HIV-1 Envelope Glycoprotein Vaccine Candidate and Its Encapsulation in Guanosine
In Vitro Supplementation of Glycine Improves Quality of Cryopreserved Bull Semen
Cultivated meat: recent technological developments, current market and future challenges
Is the development of low-cost media one of the greatest challenges to produce cultivated meat on an industrial scale?
Roles and mechanisms of methionine on milk productivity of dairy cows
Effects of dandelion (Taraxacum sp.,) supplements on lactation performance, antioxidative activity, and plasma metabolom
Effect of different levels of protein concentrates supplementation on the growth performance, plasma amino acids profile
Production Processes for Monoclonal Antibodies
Challenges and Emerging Technologies in Biomanufacturing of Monoclonal Antibodies (mAbs)
Characterization of Yeast Protein Hydrolysate for Potential Application as a Feed Additive
Effect of Saccharomyces cerevisiae Fermentation Product on Ruminal Fermentation, Blood Metabolites, and Milk Production
A dynamic metabolic flux analysis (DMFA) model for performance predictions of diverse CHO cell culture process modes and
Marked variations in gut microbiota and some innate immune responses of fresh water crayfish, marron (Cherax cainii, Aus