novasign · 445 papers with claims · 366 for outreach · 47 old · 32 reviews
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Towards a digital twin: a hybrid data‐driven and mechanistic digital shadow to forecast the evolution of lignocellulosic
Design of a microfluidic mixer channel: First steps into creating a fluorescent dye-based biosensor for mAb aggregate de
Intelligent process development — An in‐line Raman‐assisted automatic cell culture process development platform
Opportunities and challenges of real-time release testing in biopharmaceutical manufacturing.
Localized Sampling Enables Monitoring of Cell State via Inline Electrospray Ionization Mass Spectrometry
Hybrid Modeling and Intensified DoE: An Approach to Accelerate Upstream Process Characterization
Label‐free live cell imaging by Confocal Raman Microscopy identifies CHO host and producer cell lines
Quality by control: Towards model predictive control of mammalian cell culture bioprocesses.
Automatic Assay Preparation Platform (A2P2) for Real-Time Critical Quality Attributes Monitoring of Cell Culture Samples
Enhancing cross‐scale Raman in‐line monitoring capability of cell culture process in large‐scale manufacturing
Explainable deep learning enhances robust and reliable real‐time monitoring of a chromatographic protein A capture step
Bridging the gap between PAT concepts and implementation: An integrated software platform for fermentation.
Capacitance spectroscopy enables real-time monitoring of early cell death in mammalian cell culture.
Influence of cell specific parameters in a dielectric spectroscopy conversion model used to monitor viable cell density
Process‐induced cell cycle oscillations in CHO cultures: Online monitoring and model‐based investigation
Influence of Produced Water and Light Irradiation on the Composition of Exopolysaccharide Produced by <i>L. amnigena</i>
Advances in bioreactor control for production of biotherapeutic products.
A multisensor approach for improved protein A load phase monitoring by conductivity‐based background subtraction of UV s
Online/at-line measurement, analysis and control of product titer and critical product quality attributes (CQAs) during
Process analytical technology implementation for protein refolding: GCSF as a case study.
Impacts on product quality attributes of monoclonal antibodies produced in CHO cell bioreactor cultures during intention
Model‐based control system design to manage process parameters in mammalian cell culture for biopharmaceutical manufactu
Online monitoring and control of upstream cell culture process using 1D and 2D-LC with SegFlow interface.
Transforming data to information: A parallel hybrid model for real‐time state estimation in lignocellulosic ethanol ferm
Development of a rapid polarized total synchronous fluorescence spectroscopy (pTSFS) method for protein quantification i
On‐line untargeted metabolomics monitoring of an <i>Escherichia coli</i> succinate fermentation process
Application of green analytical chemistry to a green chemistry process: Magnetic resonance and Raman spectroscopic proce
Comparison of UV‐ and Raman‐based monitoring of the Protein A load phase and evaluation of data fusion by PLS models and
Robotic integration enables autonomous operation of laboratory scale stirred tank bioreactors with model‐driven process
Cell culture product quality attribute prediction using convolutional neural networks and Raman spectroscopy
Control of surge tanks for continuous manufacturing of monoclonal antibodies.
Bioprocess in-line monitoring using Raman spectroscopy and Indirect Hard Modeling (IHM): A simple calibration yields a r
A low‐temperature SPR‐based assay for monoclonal antibody galactosylation and fucosylation assessment using FcγRIIA/B
Real‐time detection of mAb aggregates in an integrated downstream process
Automated calibration and in‐line measurement of product quality during therapeutic monoclonal antibody purification usi
Nonlinear state estimation as tool for online monitoring and adaptive feed in high throughput cultivations
Integration of just‐in‐time learning with variational autoencoder for cell culture process monitoring based on Raman spe
Monitoring of the Biotechnological Production of Dihydroxyacetone Using a Low‐Field <sup>1</sup>H NMR Spectrometer
Bioprocess in‐line monitoring and control using Raman spectroscopy and Indirect Hard Modeling (IHM)
Vaccine process technology—A decade of progress
An adaptive soft-sensor for advanced real-time monitoring of an antibody-drug conjugation reaction.
NIR spectroscopy—CNN‐enabled chemometrics for multianalyte monitoring in microbial fermentation
Predictive modeling for cell culture in commercial manufacturing of biotherapeutics
Implementation of Innovative Process Analytical Technologies to Characterize Critical Quality Attributes of Co-Formulate
Temporal Galactose‐Manganese Feeding in Fed‐Batch and Perfusion Bioreactors Modulates UDP‐Galactose Pools for Enhanced m
Defining Golden Batches in Biomanufacturing Processes From Internal Metabolic Activity to Detect Process Changes That Ma
Development of Raman Spectroscopy and Machine Learning Methods for Protein Aggregate Quantification: Application to BSA
A Setup for Automatic Raman Measurements in High‐Throughput Experimentation
Towards Rapid Calibration of Bioprocess Quantification Models Using Single Compound Raman Spectra: A Comparison of Four
On‐line targeted metabolomics for real‐time monitoring of relevant compounds in fermentation processes
Less Is More: Practical Insights Into Multivariate Regression Models for Raman Spectroscopy in Bioprocess Monitoring
Characterization of mammalian cell culture raw materials by combining spectroscopy and chemometrics
Glucose monitoring and adaptive feeding of mammalian cell culture in the presence of strong autofluorescence by near inf
Raman based chemometric model development for glycation and glycosylation real time monitoring in a manufacturing scale
Multivariate data analysis on multisensor measurement for inline process monitoring of adenovirus production in HEK293 c
Comparison of spectroscopy technologies for improved monitoring of cell culture processes in miniature bioreactors
Interest of locally weighted regression to overcome nonlinear effects during in situ NIR monitoring of CHO cell culture
Inline noninvasive Raman monitoring and feedback control of glucose concentration during ethanol fermentation
An assessment of the impact of Raman based glucose feedback control on CHO cell bioreactor process development.
Tuning monoclonal antibody galactosylation using Raman spectroscopy-controlled lactic acid feeding.
Monitoring mAb cultivations with in-situ raman spectroscopy: The influence of spectral selectivity on calibration models
Raw material quality assessment approaches comparison in pectin production
Comparison of time‐gated surface‐enhanced raman spectroscopy (TG‐SERS) and classical SERS based monitoring of <i>Escheri
Rapid total sialic acid monitoring during cell culture process using a machine learning model based soft sensor.
Minimizing batch-to-batch variability of a live virus vaccine by process analytical technologies.
Innovative methodology for flexible monitoring of various bioprocesses by using pre-existing Raman data coupled with aut
Application of a fluorescent dye‐based microfluidic sensor for real‐time detection of mAb aggregates
Real time on‐line amino acid analysis to explore amino acid trends and link to glycosylation outcomes of a model monoclo
An adaptive modeling approach using spiking‐augmentation method to improve chemometric model performance in bioprocess m
Near-infrared spectroscopy coupled with convolutional neural network as a checkpoint tool for cell culture bioprocess me
Cell Culture Media and Raman Spectra Preprocessing Procedures Impact Glucose Chemometrics
Exploring the potential of machine learning for more efficient development and production of biopharmaceuticals.
A recurrent neural network for soft sensor development using CHO stable pools in fed‐batch process for SARS ‐ CoV ‐2 spi
Sensors for disposable bioreactors
Novel approach for the prediction of cell densities and viability in standardized translucent cell culture biochips with
Progress of Complex System Process Analysis Based on Modern Spectroscopy Combined With Chemometrics
A novel LED‐based 2D‐fluorescence spectroscopy system for in‐line bioprocess monitoring of Chinese hamster ovary cell cu
Lean Chemometrics in Spectroscopic Process Analytical Technology
Advanced monitoring and control of pharmaceutical production processes with <i>Pichia pastoris</i> by using Raman spectr
Continuous glucose feedback control using Raman spectroscopy and deep learning models for biopharmaceutical processes.
Enabler for process analytical technology implementation in Pichia pastoris fermentation: Fluorescence-based soft sensor
In-line monitoring of protein concentration with MIR spectroscopy during UFDF.
Soft sensor based on 2D-fluorescence and process data enabling real-time estimation of biomass in Escherichia coli culti
Real-Time VCC Monitoring and Forecasting in HEK-Cell-Based rAAV Vector Production Using Capacitance Spectroscopy.
Optimization of a mAb production process with regard to robustness and product quality using quality by design principle
Raman‐Enabled Predictions of Protein Content and Metabolites in Biopharmaceutical <i>Saccharomyces cerevisiae</i> Fermen
A Novel Raman-Chromatography Assembly for Automated Calibration and In-Line Monitoring in Bioprocessing.
Towards robust cell culture processes — Unraveling the impact of media preparation by spectroscopic online monitoring
Automized inline monitoring in perfused mammalian cell culture by MIR spectroscopy without calibration model building
Integrated SegFlow, µSIA, and UPLC for Online Sialic Acid Quantitation of Glycoproteins Directly from Bioreactors
In‐line monitoring of amino acids in mammalian cell cultures using raman spectroscopy and multivariate chemometrics mode
Process analytical technique ( PAT ) miniaturization for monoclonal antibody aggregate detection in continuous downstrea
Raman Spectroscopy as a Tool for Real‐Time Nutrient Monitoring in Bioreactor Cultivation of Microalgae
Prediction of intensified ethanol fermentation of sugarcane using a deep learning soft sensor and process analytical tec
Calibration transfer for bioprocess Raman monitoring using Kennard Stone piecewise direct standardization and multivaria
Feasibility assessment of a low‐cost near‐infrared spectroscopy‐based prototype for monitoring polyphenol extraction in
Sustainability impacts for converting to Raman spectroscopy inline monitoring from traditional offline manual sampling i
Uncertainty Quantification Using Ensemble Learning and Monte Carlo Sampling for Performance Prediction and Monitoring in
Turbidimetry and Dielectric Spectroscopy as Process Analytical Technologies for Mammalian and Insect Cell Cultures.
Multi‐dimensional technology – Recent advances and applications for biotherapeutic characterization
Cavity‐Like Silver Aggregates‐Based Colloidal SERS Microfluidic Platform for Highly Reproducible Online Reaction Process
Autoencoding Raman Spectra to Predict Analyte Concentrations
A novel rapid analysis using mass spectrometry to evaluate downstream refolding of recombinant human insulin-like growth
Multi-attribute PAT for UF/DF of Proteins-Monitoring Concentration, particle sizes, and Buffer Exchange.
Multivariate data analysis of capacitance frequency scanning for online monitoring of viable cell concentrations in smal
Spectroscopic sensors for in-line bioprocess monitoring in research and pharmaceutical industrial application.
Direct optical detection of cell density and viability of mammalian cells by means of UV/VIS spectroscopy.
Use of near-infrared spectroscopy (NIRs) in the biopharmaceutical industry for real-time determination of critical proce
Process analytical technology (PAT) tools: Uses in pharmaceutical manufacturing
Advanced process design and understanding of continuous twin-screw granulation via implementation of in-line process ana
An integrated perspective on measuring cytokines to inform CAR-T bioprocessing
Advances and opportunities in process analytical technologies for viral vector manufacturing.
PAT-on-a-chip: Miniaturization of analytical assays towards data-driven bioprocess development and optimization.
Application of Raman spectroscopy during pharmaceutical process development for determination of critical quality attrib
Harnessing Raman spectroscopy for cell therapy bioprocessing.
Comparison of chemometrics strategies for the spectroscopic monitoring of active pharmaceutical ingredients in chemical
Digital Butterworth filter as preprocessing method for implementing Raman spectroscopy as an analytical method in downst
Knowing more from less: miniaturization of ligand-binding assays and electrophoresis as new paradigms for at-line monito
Proof-of-concept analytical instrument for label-free optical deconvolution of protein species in a mixture.
Antibody glycan quality predicted from CHO cell culture media markers and machine learning
New unique PAT method and instrument for real-time inline size characterization of concentrated, flowing nanosuspensions
Process analytical technology as in-process control tool in semi-continuous manufacturing of PLGA/PEG-PLGA microspheres.
An examination of process models and model risk frameworks for pharmaceutical manufacturing
In situ monitoring of cocrystals in formulation development using low-frequency Raman spectroscopy.
Near Infrared Spectroscopy as a PAT tool for monitoring and control of protein and excipient concentration in ultrafiltr
Towards Point-of-Care Manufacturing and Analysis of Immediate-Release 3D Printed Hydrocortisone Tablets for The Treatmen
Power and fluid stress in disposable square stirred tank to streamline pharmaceutical process development.
Longitudinal two-dimensional gas chromatography mass spectrometry as a non-destructive at-line monitoring tool during ce
Bridging process diversity in cell therapies toward standardization of manufacturing workflows.
The integration of artificial intelligence through quality by digital design for sustainable pharmaceutical manufacturin
Raman spectroscopy for adaptive process control of adoptive T-cell immunotherapy manufacture
A universal digital control concept for end-to-end manufacturing.
Deployment of metabolic heat rate based soft sensor for estimation and control of specific growth rate in glycoengineere
Real-time process monitoring in a semi-continuous fluid-bed dryer - microwave resonance technology versus near-infrared
Early detection and metabolic pathway identification of T cell activation by in-process intracellular mass spectrometry.
Development of process analytical technology to monitor the cell secretome during differentiation of pluripotent stem ce
Automated vertical wheel bioreactor integrated with process analytics for T-cell manufacturing.
Foundation model cascades enable zero-shot microscopy image analysis for cell therapy manufacturing.
Development and validation of in-line near-infrared spectroscopy based analytical method for commercial production of a
Soft sensor for viable cell counting by measuring dynamic oxygen uptake rate.
Improving reliability of Raman spectroscopy for mAb production by upstream processes during bioprocess development stage
Use of Raman spectroscopy and PLS for the quantification of critical quality attributes in biopharmaceutical products.
Process Analytical Technologies and Data Analytics for the Manufacture of Monoclonal Antibodies.
Near-infrared spectroscopy based monitoring of all 20 amino acids in mammalian cell culture broth.
Characterization of Protein Aggregation Using Hydrogel-Encapsulated nIR Fluorescent Nanoparticle Sensors.
Excitation–Emission Matrix Fluorescence Spectroscopy Coupled with PARAFAC Modeling for Viability Prediction of Cells
Artificial Intelligence in Pharmaceutical Manufacturing: Applications, Case Studies, and GxP Implementation Consideratio
On-Line Ion Exchange Liquid Chromatography as a Process Analytical Technology for Monoclonal Antibody Characterization i
Real-Time Bioconjugation Reaction Monitoring of Antibody-Drug Conjugates with Multiattribute High-Throughput Hydrophobic
Toward biotherapeutic product real-time quality monitoring.
In-line product quality monitoring during biopharmaceutical manufacturing using computational Raman spectroscopy
Development of automated metabolite control using mid-infrared probe for bioprocesses and vaccine manufacturing
Application of recurrent neural network for online prediction of cell density of recombinant Pichia pastoris producing H
A framework for transferring sinomenine hydrochloride sustained-release tablet from batch to continuous direct compressi
Using Compact <sup>1</sup>H NMR, NIR, and Raman Spectroscopy Combined with Multivariate Data Analysis to Monitor a Bioca
Rapid and Nondestructive Detection of Proline in Serum Using Near‐Infrared Spectroscopy and Partial Least Squares
Development of Raman Calibration Model Without Culture Data for In-Line Analysis of Metabolites in Cell Culture Media
Calibration Transfer Across Instrument Vendors for Bioprocess Raman Monitoring
Multivariate data analysis of near-infrared spectra of cultivation medium powders for mammalian cells
Monitoring lactic acid concentrations by infrared spectroscopy: A new developed method for Lactobacillus fermenting medi
Tumor-infiltrating lymphocyte therapies: personal, powerful, with possibilities for improvement
Bioprozessanalytik mittels Raman- und MIR-ATR-Spektroskopie
Machine Learning algorithms for in-line monitoring during Yeast Fermentations based on Raman Spectroscopy
Exploring multiple bioprocess monitoring modalities for Large-scale 3D Bioprinted Tissue Cultivation
Real-time and on-line parallel detection of key fermentation process parameters by near-infrared spectroscopy in differe
A hierarchical model combining process and Raman spectroscopic data for real-time monitoring of cell culture process
Real-time and on-line monitoring of ethanol fermentation process by viable cell sensor and electronic nose
Optics miniaturization strategy for demanding Raman spectroscopy applications
Articulation of Quality By Design Elements for Product Development and its Unique Applications
Spectroscopy as a tool for process development and control in cultured meat production by analyzing media composition
Monitoring PHB production in Synechocystis sp. with hyperspectral images
Raman (Rs) Spectroscopy for Biopharmaceutical Quality Control and PAT. Raw Material - Final Products: the Nanolipids Eff
Monitoring Cell Development via In Situ Localized Sampling
Online/At-line Measurement, Analysis and Control of Product Titer & Critical Product Quality Attributes (CQAs) Durin
Probing multivalent particle–surface interactions using a quartz crystal resonator
Uncovering the Impact of Spectroscopic Data Reduction Techniques on the Process Control Mode Pattern Recognition: The Ca
Modeling of a spiral resonant sensor for biological process monitoring
Bioprocess monitoring using sequential injection capillary electrophoresis
Development of soft sensors for monitoring and control of bioprocesses
Real-time in situ monitoring of CRM-197 and polysaccharide conjugation reaction by fluorescence spectroscopy.
A Bluetooth Low-Energy Wireless Sensor Platform for Continuous Monitoring of a Bioreactor Environment during Cell Manufa
Process analytical technology (PAT) for CGT: User requirements specifications
QbD Approach in Method Development
An Overview on Quality by Design in Pharmaceutical Product Development
Limitations of Joint and Dual Nonlinear Kalman Estimators in Low-Cost Bioprocess Monitoring
Quality by Design Approch Based in Analytical Method Validation
- **DOI:** 10.5281/zenodo.5176016 - **Authors:** Y. AchyuthaValliDevi, M. SaiRamya, Likitha, S. NatrajK - **Year:** 2021
Online HPLC–HRMS Platform: The Next-Generation Process Analytical Technology Tool for Real-Time Monitoring of Antibody Q
PAT-on-a-chip: Miniaturization of analytical assays towards data-driven bioprocess development and optimization.
Computationally aided reliability analysis of sensor data using multivariate data analysis and modelling approaches for
Design, Fabrication and Assessment of a Short Tank Internally-Illuminated Concentric-Tube Airlift Photobioreactor for th
Farmasötik İlaçlar İçin Non invasif Kalite Kontrol Yöntemlerinin Tasarlanması
Determination of Chinese hamster ovary (CHO) cell densities and antibody titers from small volumes of cell culture super
A robust flow cytometry-based biomass monitoring tool enables rapid at-line characterization of S. cerevisiae physiology
Becoming fully circular facilitated by PAT
Monitoring of ultra- and diafiltration processes by Kalman-filtered Raman measurements
Synthetic spectral libraries for Raman model calibration
Wanted: more monitoring and control during inclusion body processing
A probabilistic model-based soft sensor to monitor lactic acid bacteria fermentations
Integrated Process Analytical Platform for Automated Monitoring of Monoclonal Antibody N-Linked Glycosylation.
Development of process analytical tools for rapid monitoring of live virus vaccines in manufacturing.
Optics miniaturization strategy for demanding Raman spectroscopy applications
Time-Resolved Pharmacological Studies using Automated, On-line Monitoring of Five Parallel Suspension Cultures
In situ monitoring of Lentilactobacillus parabuchneri biofilm formation via real-time infrared spectroscopy
Elucidating time-resolved intracellular metabolic dynamics <i>via</i> label-free Raman microspectroscopy and 2D correlat
Machine learning and metabolic modelling assisted implementation of a novel process analytical technology in cell and ge
Exploration of linear and interpretable models for quantification of cell parameters via contactless short-wave infrared
Improving the Model Migration Ability by a Hyperspectral Method With a High Spatial Resolution
Ultrasonic Techniques for Liquids Characterisation
REAL-TIME AT-LINE MONITORING OF INFLUENZA VIRUS IN CELL CULTURE BY A SURFACE PLASMON RESONANCE BIOSENSOR
Real-time and on-line monitoring of ethanol fermentation process by viable cell sensor and electronic nose
Raman spectroscopy online monitoring of biomass production, intracellular metabolites and carbon substrates during subme
Application of near-infrared spectroscopy technology in the complex fermentation system to achieve high-efficiency produ
Machine Learning-Enabled NIR Spectroscopy. Part 3: Hyperparameter by Design (HyD) Based ANN-MLP Optimization, Model Gene
Quantitative Comparison and Clustering of Circular Dichroism Spectra Using a Symmetrized Weighted Spectral Difference
Application of vibrational spectroscopies as process analytical techniques for monitoring fermentation and the conversio
- **Authors:** Y. Havrylko, O. A. Kurchenko, I. Tereshchenko, A. Tereshchenko - **Year:** 2019 - **Journal:** Radio Elec
Entwicklung und Charakterisierung eines neuen Fluoreszenzsensors für die online-Überwachung von Bioprozessen
Fourier-transform infrared spectroscopy and machine learning to predict amino acid content of nine commercial insects
Overview: flexible and versatile approach of quality by design & process analytical technology in industries
Raman Spectroscopy for Quantitative Analysis in the Pharmaceutical Industry
Enhanced optical detection of chemical and biological species with volume-shrinkable hydrogel and AI-assisted spectrum a
Co-clustering the data of multivariate quality attributes for the estimation of mutual influence factors
Developing Magnetic Resonance Based Analytics to Support Continuous Bioprocess
Investigation of Differences in the Cultivation of Nannochloropsis and Chlorella species by Fourier-transform Infrared S
Quality-by-design in pharmaceutical development: From current perspectives to practical applications.
- **Authors:** Є. В. Гаврилко, Олег Анастасійович Курченко, Ігор Володимирович Терещенко, Антон Ігорович Терещенко - **Y
Raman spectroscopy for multiplexed protein detection in tissue bioreactors
Calibration-free PAT: Locating selective crystallization or precipitation sweet spot in screenings with multi-way PARAFA
Spectroscopic insights into multi-phase protein crystallization in complex lysate using Raman spectroscopy and a particl
Advancement of sensor technology for monitoring and control of upstream bioprocesses
A Lightweight convolutional neural network for nicotine prediction in tobacco by near-infrared spectroscopy
Applications of Fourier Transform-Infrared spectroscopy in microbial cell biology and environmental microbiology: advanc
Estimating Extrinsic Dyes for Fluorometric Online Monitoring of Antibody Aggregation in CHO Fed-Batch Cultivations
Application of Raman Spectroscopy and Univariate Modelling As a Process Analytical Technology for Cell Therapy Bioproces
Multivariate Curve Resolution and Carbon Balance Constraint to Unravel FTIR Spectra from Fed-Batch Fermentation Samples
Online 2D Fluorescence Monitoring in Microtiter Plates Allows Prediction of Cultivation Parameters and Considerable Redu
Multi-Sensing Monitoring of the Microalgae Biomass Cultivation Systems for Biofuels and Added Value Products Synthesis—C
Next-Generation Chemical Sensors: The Convergence of Nanomaterials, Advanced Characterization, and Real-World Applicatio
Assessment of Biotechnologically Important Filamentous Fungal Biomass by Fourier Transform Raman Spectroscopy
Analysis of the Composition of Different Instars of Tenebrio molitor Larvae using Near-Infrared Reflectance Spectroscopy
Controlled Release of D-Limonene from Biodegradable Films with Enzymatic Treatment
Digital Twin Implementation for Manufacturing of Adjuvants
Halfway to Automated Feeding of Chinese Hamster Ovary Cells.
Batch Process Optimization Using Multi-Variate Data Analysis (MVDA)
Challenges and Opportunities in the Process Development of Chimeric Vaccines
Comparison of different model-based observers for monitoring substrate and product concentrations in a Penicillium chrys
Development and characterisation of a new fluorescence sensor for online monitoring of bioprocesses
A customized stand-alone photometric Raman sensor applicable in explosive atmospheres: a proof-of-concept study
PAT and automation strategies for the process development of PEGylated proteins
Soft Sensors for Biomass Monitoring during Low Cost Cellulase Production
Process Analytical Technology (PAT) Model Lifecycle Management
Mathematical decomposition and multivariate analysis applied to Raman imaging
Untitled
Spectroscopy as Process Analytical Technology for Preparative Protein Purification
Quantitative analysis of glycerol concentration in red wine using Fourier transform infrared spectroscopy and chemometri
An environmental metabolomics study of the effect of abiotic substances on Pseudomonas putida by employing analytical te
Modelling Bacterial Growth for Applying Photodynamic Therapy with Indocyanine Green
Assessment of Embryo Health and Circulating Tumor Cell Metabolism Using the Phasor-FLIM Approach
Effect of mesenchymal stem cell source on the molecular profile of extracellular vesicles for cell therapy
Seleção de variáveis baseada na integração de ranking de importância SVD com métodos de aprendizagem de máquina
Screening and Engineering Phenotypes using Big Data Systems Biology
Single cell analysis and quantitative modelling of ion concentrations and dielectric properties of Chinese hamster ovary
Valorisation of olive mill solid waste through the production of volatile fatty acids within a biorefinery approach
de Juan, Anna; de Oliveira
anna.dejuan@ub.edu
Hyperspectral image and chemometrics. A step beyond classical spectroscopic PAT tools.
ViewCarole; Goodacre, Royston
roy.goodacre@manchester.ac.uk
Metabolic analysis of the response of Pseudomonas putida DOT-T1E strains to toluene using Fourier transform infrared spe
ViewI.; Beutel, Sascha
Beutel@iftc.uni-hannover.de
Software sensors in the monitoring of microalgae cultivations
ViewPeng Zheng; Lintong Wu; Michael Ka Ho Lee; Andy Nelson; Michael J. Betenbaugh; Ishan Barman
ibarman@jhu.edu
Deep Learning-Powered Colloidal Digital SERS for Precise Monitoring of Cell Culture Media
ViewAron Gyorgypal; O. Potter; Antash Chaturvedi; David N. Powers; S. Chundawat
shishir.chundawat@rutgers.edu
Automated Workflow for Instant Labeling and Real-Time Monitoring of Monoclonal Antibody N-Glycosylation
ViewReaction kinetics of procainamide dye derivatization of N-linked glycans to enable robust process analytical workflows f
ViewKaspersetz, Lucas; Waldburger
L.Kaspersetz@tu-berlin.de
Automated Bioprocess Feedback Operation in a High-Throughput Facility via the Integration of a Mobile Robotic Lab Assist
ViewYaginuma, Keita; Tanabe
yaginuma.keita.d4@daiichisankyo.co.jp
Prediction Performance and Economic Efficiency of Soft Sensors for in-Line Water Content Monitoring in Fluidized Bed Gra
ViewLuca; Hubbuch, Jürgen
juergen.hubbuch@kit.edu
Raman-based PAT for multi-attribute monitoring during VLP recovery by dual-stage CFF: attribute-specific spectral prepro
ViewWatson, Nicholas J.; Bowler
nicholas.watson@nottingham.ac.uk
Intelligent Sensors for Sustainable Food and Drink Manufacturing
Viewmarkus.brandstetter@recendt.at
Probeless non-invasive near-infrared spectroscopic bioprocess monitoring using microspectrometer technology
oliver.spadiut@tuwien.ac.at
A novel toolbox for E. coli lysis monitoring
karen.esmonde-white@endress.com
The role of Raman spectroscopy in biopharmaceuticals from development to manufacturing.
msegundo@ff.up.pt
Biopharmaceutical analysis — current analytical challenges, limitations, and perspectives
martin.jaeger@hs-niederrhein.de
A process analyzer assembly for real-time automated near-infrared, Raman, and proton nuclear magnetic resonance spectros
maria.careri@unipr.it
Metrological traceability in process analytical technologies and point-of-need technologies for food safety and quality
matthias.franzreb@kit.edu
Micro simulated moving bed chromatography-mass spectrometry as a continuous on-line process analytical tool
m.e.klijn@tudelft.nl
Single compound data supplementation to enhance transferability of fermentation specific Raman spectroscopy models
bkozma@mail.bme.hu
On-line glucose monitoring by near infrared spectroscopy during the scale up steps of mammalian cell cultivation process
Jochen.Scholz@sartorius.com
Monitoring online biomass with a capacitance sensor during scale-up of industrially relevant CHO cell culture fed-batch
barbara.giussani@uninsubria.it
A New Index to Detect Process Deviations Using IR Spectroscopy and Chemometrics Process Tools
andersonca@duq.edu
Enhancing analytical sensitivity in upstream bioprocess using time-gated Raman spectroscopy.
kim.brettschneider@uni-hohenheim.de
Spectroscopic-Based Prediction of Milk Foam Properties for Barista Applications
lyang@lectenz.com
Simplifying the detection and monitoring of protein glycosylation during in vitro glycoengineering
tanemura.hiroki.ij@daiichisankyo.co.jp
Comprehensive modeling of cell culture profile using Raman spectroscopy and machine learning
n.szita@ucl.ac.uk
Integration and application of optical chemical sensors in microbioreactors
eirik.almklov.magnussen@nmbu.no
Deep learning-enabled Inference of 3D molecular absorption distribution of biological cells from IR spectra
mmccorry@armiusa.org
Sensor technologies for quality control in engineered tissue manufacturing
huangq@ipp.ac.cn
Improved production of polysaccharides in Ganoderma lingzhi mycelia by plasma mutagenesis and rapid screening of mutated
terrance.wilms@tu-berlin.de
Raman-guided Sample Subset Selection for Cost-efficient Offline Calibration in Bioprocesses
ives.yoplac@untrm.edu.pe
Prediction of citral superficial content on microparticles by NIR spectroscopy and partial least square regression
david.palmer@strath.ac.uk
Bioprocess monitoring applications of an innovative ATR-FTIR spectroscopy platform
asrathore@biotechcmz.com
Deep neural network for prediction and control of permeability decline in single pass tangential flow ultrafiltration in
Nico.Boon@UGent.be
Opportunities in optical and electrical single-cell technologies to study microbial ecosystems
s.goldrick@ucl.ac.uk
Influence of Incident Wavelength and Detector Material Selection on Fluorescence in the Application of Raman Spectroscop
f.braun@hs-mannheim.de
Comparison of Raman and Mid-Infrared Spectroscopy for Real-Time Monitoring of Yeast Fermentations: A Proof-of-Concept fo
manon.th.weiske@campus.tu-berlin.de
In-Line Monitoring of Polyhydroxyalkanoate (PHA) Production during High-Cell-Density Plant Oil Cultivations Using Photon
mila.djisalov@biosense.rs
Cultivating Multidisciplinarity: Manufacturing and Sensing Challenges in Cultured Meat Production
ypzhuang@ecust.edu.cn
From Spatial-Temporal Multiscale Modeling to Application: Bridging the Valley of Death in Industrial Biotechnology
kornecki@itv.tu-clausthal.de
Process Analytical Technology for Advanced Process Control in Biologics Manufacturing with the Aid of Macroscopic Kineti
kilian.hartmann@h-ab.de
Representative Sampling Implementation in Online VFA/TIC Monitoring for Anaerobic Digestion
j.chapman@cqu.edu.au
The Use of UV-Vis Spectroscopy in Bioprocess and Fermentation Monitoring
anurag.khetan@bms.com
N-1 Perfusion Platform Development Using a Capacitance Probe for Biomanufacturing
ml.musa@qut.edu.au
Factors Affecting Microalgae Production for Biofuels and the Potentials of Chemometric Methods in Assessing and Optimizi
davor.valinger@pbf.unizg.hr
Application of Spectroscopy Techniques for Monitoring (Bio)Catalytic Processes in Continuously Operated Microreactor Sys
peter.kaul@h-brs.de
Discrimination of Stressed and Non-Stressed Food-Related Bacteria Using Raman-Microspectroscopy
splin0330@tmu.edu.tw
Informative Wavelength Selection for Evaluation of Bacterial Spoilage in Raw Salmon (Salmo salar) Fillet Using FT-NIR Sp
aybike.cebeci@marmara.edu.tr
Characterization and Viability Prediction of Commercial Probiotic Supplements under Temperature and Concentration Condit
alexander.bowler@nottingham.ac.uk
Predicting Alcohol Concentration during Beer Fermentation Using Ultrasonic Measurements and Machine Learning
leeys@illinois.edu
Characterizing Spray-Dried Powders through NIR Spectroscopy: Effect of Two Preparation Strategies for Calibration Sample
m.kulisz@pollub.pl
Process Control via Electrical Impedance Tomography for Energy-Aware Industrial Systems
ilham@um.edu.my
Smart Fermentation Technologies: Microbial Process Control in Traditional Fermented Foods
habeebbabatunde@u.boisestate.edu
SVR Chemometrics to Quantify β-Lactoglobulin and α-Lactalbumin in Milk Using MIR
pengwang@ouc.edu.cn
Comparative Analysis of XGB, CNN, and ResNet Models for Predicting Moisture Content in Porphyra yezoensis Using Near-Inf
drupad.trivedi@manchester.ac.uk
Metabolic Fingerprinting of Pseudomonas putida DOT-T1E Strains: Understanding the Influence of Divalent Cations in Adapt
sandra.frempong@uni-jena.de
Illuminating the Tiny World: A Navigation Guide for Proper Raman Studies on Microorganisms
yangsw@hfnu.edu.cn
Aspects and Implementation of Pharmaceutical Quality by Design from Conceptual Frameworks to Industrial Applications.
weiqiang@chinacdc.cn
Genotypic and Phenotypic Characterisation of Staphylococcus aureus Enterotoxins Using Single-Cell Raman Spectroscopy and
juan-sebastian.reyes@polymtl.ca
Modern Sensor Tools and Techniques for Monitoring, Controlling, and Improving Cell Culture Processes
gavin.walker@ul.ie
Merging Real-Time NIR and Process Parameter Measurements in a Fluidized Bed Granulation Process to Predict Particle Size
MATTHEW.2.SANDERS@GSK.COM
Working within the Design Space: Do Our Static Process Characterization Methods Suffice?
ji_kaidi@163.com
Automatic Control of Nucleation and Crystal Growth Using Online Raman Analyzer
minsookim@pusan.ac.kr
Process Analytical Technology Tools for Monitoring Pharmaceutical Unit Operations: A Control Strategy for Continuous Pro
massimiliano.grosso@unica.it
Raman Spectroscopy Coupled with Multivariate Statistical Process Control for Detecting Anomalies During Milk Coagulation
davide.fissore@polito.it
NIR-Based Real-Time Monitoring of Freeze-Drying Processes: Application to Fault and Endpoint Detection
morandise.rubini@univ-tours.fr
Monitoring of Nutrients, Metabolites, IgG Titer, and Cell Densities in 10 L Bioreactors Using Raman Spectroscopy and PLS
strube@itv.tu-clausthal.de
Accelerating Biomanufacturing by Modeling of Continuous Bioprocessing—Piloting Case Study of Monoclonal Antibody Manufac
vignesh.rajamanickam@tuwien.ac.at
A Chemometric Tool to Monitor and Predict Cell Viability in Filamentous Fungi Bioprocesses Using UV Chromatogram Fingerp
dpais@ibet.pt
Dielectric Spectroscopy to Improve the Production of rAAV Used in Gene Therapy
Ashish.Kumar@UGent.be
Why Is Batch Processing Still Dominating the Biologics Landscape? Towards an Integrated Continuous Bioprocessing Alterna
rudibert.king@tu-berlin.de
Model-Based Process Optimization for the Production of Macrolactin D by Paenibacillus polymyxa
lohmann@itv.tu-clausthal.de
Process Analytical Technology for Precipitation Process Integration into Biologics Manufacturing towards Autonomous Oper
olivier.henry@polymtl.ca
On the Use of Surface Plasmon Resonance-Based Biosensors for Advanced Bioprocess Monitoring
Nicolas.Voelcker@monash.edu
Recent Progress in Lab-On-a-Chip Systems for the Monitoring of Metabolites for Mammalian and Microbial Cell Research
w.yu@auckland.ac.nz
Wavelength Selection FOR Rapid Identification of Different Particle Size Fractions of Milk Powder Using Hyperspectral Im
jens.kastenhofer@tuwien.ac.at
Monitoring E. coli Cell Integrity by ATR-FTIR Spectroscopy and Chemometrics: Opportunities and Caveats
helgers@itv.tu-clausthal.de
Towards Autonomous Operation by Advanced Process Control—Process Analytical Technology for Continuous Biologics Antibody
Jianwei.qin@ars.usda.gov
Improving Sensitivity in Raman Imaging for Thin Layered and Powdered Food Analysis Utilizing a Reflection Mirror
a.ndour@cgiar.org
NIR Instruments and Prediction Methods for Rapid Access to Grain Protein Content in Multiple Cereals
bruno.wacogne@univ-fcomte.fr
Absorption Spectra Description for T-Cell Concentrations Determination and Simultaneous Measurements of Species during C
zyxia@zju.edu.cn
Rapid Determination of Chlorogenic Acid, Luteoloside and 3,5-O-dicaffeoylquinic Acid in Chrysanthemum Using Near-Infrare
steven.short@merck.com
Automated Data Generation for Raman Spectroscopy Calibrations in Multi-Parallel Mini Bioreactors.
david.nettleton@iris-eng.com
Smart Sensor Control and Monitoring of an Automated Cell Expansion Process
yvonne.joseph@esm.tu-freiberg.de
Aerogel-Lined Capillaries as Liquid-Core Waveguides for Raman Signal Gain of Aqueous Samples: Advanced Manufacturing and
malini.mukherjee@merck.com
Rapid In-Process Measurement of Live Virus Vaccine Potency Using Laser Force Cytology: Paving the Way for Rapid Vaccine
omar.dib@univ-nantes.fr
Development and Application of an Automated Raman Sensor for Bioprocess Monitoring: From the Laboratory to an Algae Prod
tugba.bayraktutan@igdir.edu.tr
Moleküler Spektroskopinin Temel Prensipleri ve Uygulamaları
thanhtung.khuat@uts.edu.au
Uncertainty Quantification Using Ensemble Learning and Monte Carlo Sampling for Performance Prediction and Monitoring in
daniel.killeen@plantandfood.co.nz
Machine Learning for Raman Spectroscopy-based Cyber-Marine Fish Biochemical Composition Analysis
susan.mcdonnell@ucd.ie
Challenges and Emerging Technologies in Biomanufacturing of Monoclonal Antibodies (mAbs)
bhavanamnagajyothi25@gmail.com
HPLC in the Era of Biopharma: Advances in Column Chemistry, Automation and Data Analytics