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Protein A Chromatography Resin Selection Lifetime

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<2016

Experimental and Theoretical Investigation of Effect of Spacer Arm and Support Matrix of Synthetic Affinity Chromatograp

2010 The Journal of Physical Chemistry B

Zamolo, Laura; Salvalaglio, Matteo; Cavallotti, Carlo et al.

DOI

High‐Throughput Process Development: Determination of Dynamic Binding Capacity Using Microtiter Filter Plates Filled wit

2008 Biotechnology Progress

Bergander, Tryggve; Nilsson‐Välimaa, Kristina; Öberg, Katarina et al.

DOI

Rational design and engineering of protein A to obtain the controlled elution profile in monoclonal antibody purificatio

2012

S. Yoshida; D. Murata; S. Taira et al.

DOI

Dynamic characterization of affinity membranes for monoclonal antibodies purification

2007 Archivio istituzionale della ricerca (Alma Mater Studiorum Università di Bologna)

Dimartino, Simone; Boi, Cristiana; Sarti, Giulio C.

Characterisation of chromatography adsorbents for antibody bioprocessing

2009 OpenGrey (Institut de l'Information Scientifique et Technique)

Sheth, Bela

Evaluation of affinity membrane adsorbers for antibody purification

2006 Archivio istituzionale della ricerca (Alma Mater Studiorum Università di Bologna)

Boi, Cristiana; Dimartino, Simone; Beijeren, Peter van et al.

Fc-binding hexamer peptide ligands for immunoglobulin purification

2008 NCSU Libraries Repository (North Carolina State University Libraries)

Yang, Haiou

Studio Sperimentale e Modellazione della Separazione di Proteine con Membrane di Affinità

2009 AMS Dottorato Institutional Doctoral Theses Repository (University of Bologna)

Dimartino, Simone

DOI

A comparison of protein A chromatographic stationary phases: performance characteristics for monoclonal antibody purific

2015 Biotechnology and applied biochemistry

Liu, Zhuo; Mostafa, Sigma S; Shukla, Abhinav A

DOI

Binding capacity differences for antibodies and Fc‐fusion proteins on protein A chromatographic materials

2007 Biotechnology and Bioengineering

Sanchayita Ghose; B. Hubbard; S. Cramer

DOI

Studying host cell protein interactions with monoclonal antibodies using high throughput protein A chromatography.

2012 Biotechnology journal

Sisodiya, Vikram N; Lequieu, Joshua; Rodriguez, Maricel et al.

DOI

Protein A chromatography at high titers.

2013 Biotechnology and bioengineering

Natarajan, Venkatesh; Zydney, Andrew L

DOI

Improved process analytical technology for protein a chromatography using predictive principal component analysis tools.

2011 Biotechnology and bioengineering

Hou, Ying; Jiang, Canping; Shukla, Abhinav A et al.

DOI

The dynamics of the CHO host cell protein profile during clarification and protein A capture in a platform antibody puri

2013 Biotechnology and bioengineering

Hogwood, Catherine E M; Tait, Andrew S; Koloteva-Levine, Nadejda et al.

DOI

Clearance of the rodent retrovirus, XMuLV, by protein A chromatography.

2015 Biotechnology and bioengineering

Bach, Julia; Connell-Crowley, Lisa

DOI

Toward improving selectivity in affinity chromatography with PEG ylated affinity ligands: The performance of PEG ylated

2014 Biotechnology Progress

González‐Valdez, José; Yoshikawa, Alex M.; Weinberg, Justin et al.

DOI

Maximizing binding capacity for protein A chromatography

2014 Biotechnology progress (Print)

Sanchayita Ghose; Jennifer Zhang; Lynn Conley et al.

DOI

Optimization and Performance of Silica‐Based Media for Industrial‐Scale Antibody Purification

2011 Chemical Engineering & Technology

Miyahara, Hirofumi; Nakashima, Rika; Inoue, Machiko et al.

DOI

Advective hydrogel membrane chromatography for monoclonal antibody purification in bioprocessing

2015 Biotechnology progress (Print)

Ying Hou; Mark Brower; D. Pollard et al.

DOI

Evaluation of a novel methacrylate-based Protein A resin for the purification of immunoglobulins and Fc-fusion proteins.

2014 Biotechnology progress

McCaw, Tyler R; Koepf, Edward K; Conley, Lynn

DOI

High‐throughput process development methods for chromatography and precipitation of proteins: Advantages and precautions

2013 Engineering in Life Sciences

Yoshimoto, Noriko; Minakuchi, Kazunobu; Itoh, Daisuke et al.

DOI

Design and characterization of a microfluidic packed bed system for protein breakthrough and dynamic binding capacity de

2009 Biotechnology Progress

Shapiro, Michael S.; Haswell, Steve J.; Lye, Gary J. et al.

DOI

Phenolics removal from transgenic Lemna minor extracts expressing mAb and impact on mAb production cost

2011 Biotechnology progress (Print)

G. Barros; S. Woodard; Z. Nikolov

DOI

Robustness of virus removal by protein A chromatography is independent of media lifetime.

2008 Journal of chromatography. A

Lute, Scott; Norling, Lenore; Hanson, Michael et al.

DOI

A mechanistic study of Protein A chromatography resin lifetime.

2009 Journal of chromatography. A

Jiang, Canping; Liu, Jing; Rubacha, Michael et al.

DOI

Improving the binding capacities of protein A chromatographic materials by means of ligand polymerization.

2014 Journal of chromatography. A

Freiherr von Roman, Matthias; Berensmeier, Sonja

DOI

Experimental characterization of the transport phenomena, adsorption, and elution in a protein A affinity monolithic med

2015 Journal of chromatography. A

Herigstad, M Omon; Dimartino, Simone; Boi, Cristiana et al.

DOI

Novel peptide ligand with high binding capacity for antibody purification.

2012 Journal of chromatography. A

Lund, Line Naomi; Gustavsson, Per-Erik; Michael, Roice et al.

DOI

Differential binding of heavy chain variable domain 3 antigen binding fragments to protein A chromatography resins.

2015 Journal of chromatography. A

Bach, Julia; Lewis, Nathaniel; Maggiora, Kathy et al.

DOI

Engineering of novel Staphylococcal Protein A ligands to enable milder elution pH and high dynamic binding capacity

2014 Journal of Chromatography A

Pabst, Timothy M.; Palmgren, Ronnie; Forss, Annika et al.

DOI

Bacteriophage and impurity carryover and total organic carbon release during extended protein A chromatography.

2009 Journal of chromatography. A

Lute, Scott; Brorson, Kurt

DOI

Effect of cleaning agents and additives on Protein A ligand degradation and chromatography performance.

2015 Journal of chromatography. A

Yang, Lihua; Harding, Jason D; Ivanov, Alexander V et al.

DOI

Metadata Only

58

Predictive mechanistic modeling of loading and elution in protein A chromatography.

2024 Journal of chromatography. A DOI

Influence of excipients in Protein A chromatography and virus inactivation.

2021 Journal of chromatography. B, Analytical technologies in the biomedical and life sciences DOI

Routes to improve binding capacities of affinity resins demonstrated for Protein A chromatography.

2016 Journal of chromatography. B, Analytical technologies in the biomedical and life sciences DOI

On-line PAT based monitoring and control of resin aging in protein A chromatography for COGs reduction.

2024 Journal of chromatography. B, Analytical technologies in the biomedical and life sciences DOI

A novel rProtein A chromatographic media for enhancing cleaning-in-place performance.

2018 Journal of immunological methods DOI

Overcoming the challenge of Protein A resin sanitisation: Evaluating the efficacy of peracetic acid as a novel sanitisat

2026 Journal of chromatography. B, Analytical technologies in the biomedical and life sciences DOI

Natural-Mimetic Spatial Distribution of Flowers and Grasses: Rapid and Efficient Antibody Separation with Jagged Dextran

2025 ACS Sustainable Chemistry & Engineering DOI

High-Efficiency Analytical Protein A Columns for High Sensitivity Monoclonal Antibody Titer Analysis.

2025 Analytical chemistry DOI

Optimization of a calcium-dependent Protein A-derived domain for mild antibody purification

2019 mAbs DOI

Protein a resin lifetime study: Evaluation of protein a resin performance with a model-based approach in continuous capt

2018 Preparative biochemistry & biotechnology DOI

Application of Raman Spectroscopy to Dynamic Binding Capacity Analysis

2023 Applied Spectroscopy DOI

Biocatalytic Method for Producing an Affinity Resin for the Isolation of Immunoglobulins.

2024 Biomolecules DOI

Comparative Evaluation of Commercial Protein A Membranes for the Rapid Purification of Antibodies.

2023 Membranes DOI

Affinity Resins for the Isolation of Immunoglobulins G Obtained Using Biocatalytic Technology.

2024 International journal of molecular sciences DOI

Preparation of Protein A Membrane Adsorbers Using Strain-Promoted, Copper-Free Dibenzocyclooctyne (DBCO)-Azide Click Che

2023 Membranes DOI

Development of a New Affinity Gold Polymer Membrane with Immobilized Protein A

2024 Membranes DOI

Microbial control and remediation of Protein A chromatography resin

2025 DOI

Antibody Binding Heterogeneity of Protein A Resins.

2019 Biotechnology journal DOI

Choosing the right protein A affinity chromatography media can remove aggregates efficiently.

2017 Biotechnology journal DOI

A multisensor approach for improved protein A load phase monitoring by conductivity-based background subtraction of UV s

2021 Biotechnology and bioengineering DOI

Polyclonal and monoclonal IgG binding on protein A resins-Evidence of competitive binding effects.

2017 Biotechnology and bioengineering DOI

Linear flow-velocity gradient chromatography-An efficient method for increasing the process efficiency of batch and cont

2021 Biotechnology and bioengineering DOI

An NIR-based PAT approach for real-time control of loading in Protein A chromatography in continuous manufacturing of mo

2020 Biotechnology and bioengineering DOI

The pearl necklace model in protein A chromatography: Molecular mechanisms at the resin interface.

2019 Biotechnology and bioengineering DOI

Development of a novel affinity chromatography resin for platform purification of bispecific antibodies with modified pr

2018 Biotechnology progress DOI

Continued insights into virus clearance validation across continuous capture chromatography.

2021 Biotechnology and bioengineering DOI

Maximizing the functional lifetime of Protein A resins.

2017 Biotechnology progress DOI

Relationship between HETP measurements and breakthrough curves in short chromatography columns

2020 Biotechnology Progress DOI

Application of inline variable pathlength technology for rapid determination of dynamic binding capacity in downstream p

2022 Biotechnology Progress DOI

Antibody purification from CHO cell supernatant using new multimodal membranes

2017 Biotechnology Progress DOI

Implementation of a fluorescence based PAT control for fouling of protein A chromatography resin

2017 Journal of Chemical Technology & Biotechnology DOI

Assessment of membrane‐based downstream purification processes as a replacement to traditional resin bead for monoclonal

2024 Biotechnology Progress DOI

A megaporous material harbouring a peptide ligand for affinity IgG purification

2017 Electrophoresis DOI

Increasing immunoglobulin G adsorption in dextran-grafted protein A gels.

2021 Engineering in life sciences DOI

A novel dextran-grafted tetrapeptide resin for antibody purification.

2020 Journal of separation science DOI

Poly(glycidyl methacrylate)‐grafted hydrophobic charge‐induction agarose resins with 5‐aminobenzimidazole as a functiona

2016 Journal of Separation Science DOI

Antibody adsorption in protein-A affinity chromatography - in situ measurement of nanoscale structure by small-angle X-r

2018 Journal of separation science DOI

Chromatography process development aided by a dye‐based assay

2019 Journal of Chemical Technology & Biotechnology DOI

Advance chromatin extraction improves the performance of electropositive mixed-mode chromatography as a capture step and

2019 Biochemical engineering journal DOI

Engineering Staphylococcal Protein A for high-throughput affinity purification of monoclonal antibodies.

2020 Biotechnology advances DOI

Process development in the Quality by Design paradigm: Modeling of Protein A chromatography resin fouling.

2018 Journal of chromatography. A DOI

Chemical modification of protein A chromatography ligands with polyethylene glycol. I: Effects on IgG adsorption equilib

2018 Journal of chromatography. A DOI

Evaluation of recent Protein A stationary phase innovations for capture of biotherapeutics

2018 Journal of Chromatography A DOI

Chemical modification of protein a chromatography ligands with polyethylene glycol. II: Effects on resin robustness and

2018 Journal of chromatography. A DOI

Mechanistic understanding of fouling of protein A chromatography resin.

2016 Journal of chromatography. A DOI

Alkaline treatment enhances mass transfer in Protein A affinity chromatography

2022 Journal of Chromatography A DOI

Online optimization of dynamic binding capacity and productivity by model predictive control

2022 Journal of Chromatography A DOI

Identification and tracking of problematic host cell proteins removed by a synthetic, highly functionalized nonwoven med

2019 Journal of chromatography. A DOI

Model based strategies towards protein A resin lifetime optimization and supervision.

2020 Journal of chromatography. A DOI

Temperature dependence of antibody adsorption in protein A affinity chromatography

2018 Journal of Chromatography A DOI

A linear epitope coupled to DsRed provides an affinity ligand for the capture of monoclonal antibodies.

2018 Journal of chromatography. A DOI

Development of temperature-controlled batch and 3-column counter-current protein A system for improved therapeutic purif

2024 Journal of chromatography. A DOI

An inert tracer: The binding site of a fluorescent dye on the antibody and its effects on Protein A chromatography.

2024 Journal of chromatography. A DOI

Modelling the mass transfer of a polysaccharide-based protein A chromatography membrane with a bimodal porous structure.

2025 Journal of Chromatography A DOI

Effect of solution condition on the binding behaviors of monoclonal antibody and fusion protein therapeutics in Protein

2022 Journal of chromatography. A DOI

Evaluation of mild pH elution protein A resins for antibodies and Fc-fusion proteins.

2024 Journal of chromatography. A DOI

Depth filter material process interaction in the harvest of mammalian cells.

2023 Biotechnology progress DOI

On-column disulfide bond formation of monoclonal antibodies during Protein A chromatography eliminates low molecular wei

2020 mAbs DOI

Needs Review

OpenAlex
3
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Krištof Bozovičar

corresponding author — no email matched

2021 Scientific Reports DOI
tomaz.bratkovic@ffa.uni-lj.si
Pending email search

Noriko Yoshimoto

corresponding author — no email matched

2016 Japan Journal of Food Engineering DOI
shuichi@yamaguchi-u.ac.jp
Pending email search

Chyi‐Shin Chen

corresponding author — no email matched

2020 JOURNAL OF CHEMICAL ENGINEERING OF JAPAN DOI
shuichi@yamaguchi-u.ac.jp

Review & Send

1
Anurag S. Rathore

asrathore@biotechcmz.com

2018

Protein A chromatography resin lifetime-impact of feed composition.

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