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Mitochondrial biogenesis: An update
Liraglutide ameliorates non-alcoholic fatty liver disease by enhancing mitochondrial architecture and promoting autophag
Autophagy in neurodegeneration: New insights underpinning therapy for neurological diseases
IL-17A-producing T cells exacerbate fine particulate matter-induced lung inflammation and fibrosis by inhibiting PI3K/Ak
Melatonin reverses H2 O2 -induced senescence in SH-SY5Y cells by enhancing autophagy via sirtuin 1 deacetylation of the
Ischaemia reperfusion injury in liver transplantation: Cellular and molecular mechanisms
Gradual downhill running improves age-related skeletal muscle and bone weakness: implication of autophagy and bone morph
Mitochondrial dysfunction in Parkinson's disease
A novel adiponectin receptor agonist (AdipoAI) ameliorates type 2 diabetes-associated periodontitis by enhancing autopha
The autophagy-enhancing drug carbamazepine improves neuropathology and motor impairment in mouse models of Machado-Josep
Rapamycin alleviates irradiation-induced parotid injury by enhancing the whole gland homeostasis.
The role of autophagy and lipid catabolism in enhancing cold stress resistance in zebrafish.
Spermidine in health and disease
Inhibition of HSPA8 by rifampicin contributes to ferroptosis via enhancing autophagy.
The role of lipids in exosome biology and intercellular communication: Function, analytics and applications
Mitochondrial Fusion Mediated by Mitofusin 1 Regulates Macrophage Mycobactericidal Activity by Enhancing Autophagy.
Tetramethylpyrazine Attenuated Sevoflurane-Induced Neurotoxicity by Enhancing Autophagy through GPR50/CREB Pathway in SH
Parkinson’s disease: etiopathogenesis and treatment
Mycobacterium tuberculosis PPE51 Inhibits Autophagy by Suppressing Toll-Like Receptor 2-Dependent Signaling.
Resveratrol attenuates hIAPP amyloid formation and restores the insulin secretion ability in hIAPP-INS1 cell line via en
Targeting Autophagy with Geniposide Ameliorates Atherosclerosis in [Formula: see text] Mice.
Electroacupuncture Improves Motor Symptoms of Parkinson's Disease and Promotes Neuronal Autophagy Activity in Mouse
Propagation of Protein Aggregation in Neurodegenerative Diseases
Alzheimer's Disease Mechanisms and Emerging Roads to Novel Therapeutics
Translating Immunology into Therapeutic Concepts for Inflammatory Bowel Disease
Brain Disorders Due to Lysosomal Dysfunction
Autophagy: A Druggable Process
β-Hydroxybutyrate: A Signaling Metabolite
Genetics and Pathogenesis of Parkinson's Syndrome
The Microbiota-Gut-Brain Axis
TFEB signaling promotes autophagic degradation of NLRP3 to attenuate neuroinflammation in diabetic encephalopathy.
Blood-Brain Barrier: From Physiology to Disease and Back
Parathyroid hormone-(1-34) ameliorated knee osteoarthritis in rats via autophagy.
Dexmedetomidine mitigates neuroinflammation and improves early postoperative neurocognitive dysfunction in rats by enhan
Mechanisms of Neuroprotection by Quercetin: Counteracting Oxidative Stress and More
Vitamin D3 improved erectile function recovery by regulating autophagy and apoptosis in a rat model of cavernous nerve i
Lysosomes as a therapeutic target
AMP-activated protein kinase: the current landscape for drug development
Context-specific regulation and function of mRNA alternative polyadenylation
Amyotrophic lateral sclerosis: a neurodegenerative disorder poised for successful therapeutic translation
The mechanisms and roles of selective autophagy in mammals.
Targeting the biology of aging with mTOR inhibitors
Autophagy-mediated clearance of ubiquitinated mutant huntingtin by graphene oxide.
MitoTimer-based high-content screen identifies two chemically-related benzothiophene derivatives that enhance basal mito
Omega-3 PUFAs improve cognitive function in heat-stressed mice by enhancing autophagy via inhibition of the phosphorylat
The protection of luteolin against diabetic cardiomyopathy in rats is related to reversing JNK-suppressed autophagy.
Enhancing cognitive memory function using Phyllanthus emblica polysaccharides via modulating autophagy and reshaping the
Citrus peel flavonoid nobiletin alleviates lipopolysaccharide-induced inflammation by activating IL-6/STAT3/FOXO3a-media
HMGB1-induced autophagy facilitates hepatic stellate cells activation: a new pathway in liver fibrosis.
Urolithin A Hijacks ERK1/2-ULK1 Cascade to Improve CD8+ T Cell Fitness for Antitumor Immunity.
Overexpression of lncRNA TCTN2 protects neurons from apoptosis by enhancing cell autophagy in spinal cord injury.
Most autophagic cell death studies lack evidence of causality.
Controlled Activation of TRPV1 Channels on Microglia to Boost Their Autophagy for Clearance of Alpha-Synuclein and Enhan
Tomatidine provides mitophagy-independent neuroprotection after ischemic injury.
Untangling the mechanism of 3-methyladenine in enhancing the specific productivity: Transcriptome analysis of recombinan
Iron and oxidizing species in oxidative stress and Alzheimer's disease
Daphnetin alleviates inflammation and promotes autophagy via the AMPK/mTOR pathway in gouty arthritis.
Autophagy drives plasticity and functional polarization of tumor‐associated macrophages
Glial Cell Line-Derived Neurotrophic Factor Enhances Autophagic Flux in Mouse and Rat Hepatocytes and Protects Against P
SecinH3 Attenuates TDP-43 p.Q331K-Induced Neuronal Toxicity by Suppressing Endoplasmic Reticulum Stress and Enhancing Au
Amino acids stimulate glycyl-tRNA synthetase nuclear localization for mammalian target of rapamycin expression in bovine
Therapeutic targeting of PFKFB3 with a novel glycolytic inhibitor PFK158 promotes lipophagy and chemosensitivity in gyne
Curcumin: A naturally occurring autophagy modulator.
Atorvastatin ameliorates LPS-induced inflammatory response by autophagy via AKT/mTOR signaling pathway.
Downregulation of miRNA-30a enhanced autophagy in osthole-alleviated myocardium ischemia/reperfusion injury.
The Multifaceted Influence of Beta-Hydroxybutyrate on Autophagy, Mitochondrial Metabolism, and Epigenetic Regulation.
Neuro death through autophagy via the acetylation of FoxO1 by SIRT2 in the hippocampus of mice in a autism spectrum diso
Enriched Environment Enhances Motor Function in Mice With Cerebral Infarction by Promoting mTOR-Dependent Autophagy in t
Adipose‐derived mesenchymal stem cells reduce autophagy in stroke mice by extracellular vesicle transfer of miR‐25
The burgeoning field of innate immune-mediated disease and autoinflammation.
Quinoa Polyphenols Alleviate Glucose Deprivation-Induced Endoplasmic Reticulum Stress by Enhancing Hepatic Cellular Auto
Flipping the Metabolic Switch: Understanding and Applying the Health Benefits of Fasting
Targeted Therapies for Parkinson's Disease: From Genetics to the Clinic
mTOR inhibition by rapamycin protects against deltamethrin-induced apoptosis in PC12 Cells.
pH-Sensitive Polymeric Nanoparticles Modulate Autophagic Effect via Lysosome Impairment.
Conditioned medium of mesenchymal stem cells delays osteoarthritis progression in a rat model by protecting subchondral
Ginsenoside Rg1 suppresses paraquat-induced epithelial cell senescence by enhancing autophagy in an ATG12-dependent mann
Hepatoprotective Effect of Trehalose: Insight into Its Mechanisms of Action.
Role of TFEB in Diseases Associated with Lysosomal Dysfunction.
Autophagy and Mitochondrial Encephalomyopathies.
Alzheimer's disease drug development pipeline: 2022
Alzheimer's disease drug development pipeline: 2024
Molecular insights into irisin's role in the regulation of programmed cell death: mechanisms and therapeutic potent
Lycium barbarum polysaccharide relieves diabetes mellitus-induced cataract by activating Sirtuin 6.
MicroRNA-146a-5p alleviates the pathogenesis of osteoarthritis by inhibiting SDF-1/CXCR4-induced chondrocyte autophagy.
Expression of miRNA-155 in carotid atherosclerotic plaques of apolipoprotein E knockout (ApoE-/-) mice and the intervent
The neuroprotection of progesterone against Aβ-induced NLRP3-Caspase-1 inflammasome activation via enhancing autophagy i
Mechanistic target of rapamycin-mediated autophagy is involved in the alleviation of lipopolysaccharide-induced acute lu
The SGLT2 inhibitor empagliflozin negatively regulates IL-17/IL-23 axis-mediated inflammatory responses in T2DM with NAF
Trichostatin A modulates the macrophage phenotype by enhancing autophagy to reduce inflammation during polymicrobial sep
TSP-1 increases autophagy level in cartilage by upregulating HSP27 which delays progression of osteoarthritis.
miR-99b-3p/Mmp13 axis regulates NLRP3 inflammasome-dependent microglial pyroptosis and alleviates neuropathic pain via t
Sirt1 alleviates osteoarthritis via promoting FoxO1 nucleo-cytoplasm shuttling to facilitate autophagy.
Liver X receptor agonist RGX-104 attenuates PHMG-induced pulmonary fibrosis by restoring autophagy-lysosome fusion and s
HNRNPA1 promotes TRIM37 mRNA stability and mediates TRAF6 ubiquitination to alleviate osteoarthritis.
Targeting the Autophagy-Lysosome Pathway in a Pathophysiologically Relevant Murine Model of Reversible Heart Failure.
Aberrant STING activation promotes macrophage senescence by suppressing autophagy in vascular aging from diabetes.
Melatonin ameliorates sepsis-induced myocardial dysfunction by promoting autophagy via SIRT1-mediated TFEB deacetylation
Jiedu Tongluo Baoshen formula enhances podocyte autophagy and reduces proteinuria in diabetic kidney disease by inhibiti
Sertad1 is elevated and plays a necessary role in neuron loss and cognitive impairment in a mouse model of Alzheimer
Modified Xiaoyao San reverses lipopolysaccharide-induced depression-like behavior through suppressing microglia M1 polar
Hyperoside alleviates epilepsy-induced neuronal damage by enhancing antioxidant levels and reducing autophagy.
Fufang zhenzhu tiaozhi capsule alleviates hypothalamic endoplasmic reticulum stress and leptin resistance through autoph
Long-term treatment of Nicotinamide mononucleotide improved age-related diminished ovary reserve through enhancing the m
Maimendong decoction modulates the PINK1/Parkin signaling pathway alleviates type 2 alveolar epithelial cells senescence
MC-LR disrupts dopamine synthesis in the substantia nigra of midbrain by enhancing the chaperone-mediated autophagy path
Rosamultin attenuates cerebral ischemia/reperfusion injury by inhibiting autophagy via the PI3K/Akt/mTOR pathway.
Paeoniflorin, ferulic acid, and atractylenolide III improved LPS-induced neuroinflammation of BV2 microglia cells by enh
HGSD attenuates neuronal apoptosis through enhancing neuronal autophagy in the brain of diabetic mice: The role of AMP-a
Antagonism of miR-429 ameliorates anoxia/reoxygenation injury in cardiomyocytes by enhancing MO25/LKB1/AMPK mediated aut
Osteoprotegerin prompts cardiomyocyte hypertrophy via autophagy inhibition mediated by FAK/BECLIN1 pathway.
l-carnitine modulates autophagy, oxidative stress and inflammation in trazodone induced testicular toxicity.
Curcumin prevents tension-induced endplate cartilage degeneration by enhancing autophagy.
Rethinking Parkinson's: The role of proteostasis networks and autophagy in disease progression.
Sulforaphane suppresses obesity-related glomerulopathy-induced damage by enhancing autophagy via Nrf2.
Cannabidiol (CBD) enhanced the hippocampal immune response and autophagy of APP/PS1 Alzheimer's mice uncovered by R
Roflumilast ameliorates ovariectomy-induced depressive-like behavior in rats via activation of AMPK/mTOR/ULK1-dependent
LncSSBP1/FOXO3 axis modulates autophagy: a novel insight into bronchial epithelial cells defense against Talaromyces mar
Levels of miR-125a-5p are altered in Mycobacterium avium-infected macrophages and associate with the triggering of an au
LPS restores protective immunity in macrophages against Mycobacterium tuberculosis via autophagy.
Autophagy: The missing link in diabetic neuropathy?
HAP1 is an in vivo UBE3A target that augments autophagy in a mouse model of Angelman syndrome.
The multifaceted role of GLP-1 in metabolic disorders, chronic inflammation, and aging: Mechanisms and therapeutic poten
miR-142-3p alleviates neuronal apoptosis in Parkinson's disease via negatively regulating C9orf72.
Aspirin restores endothelial function by mitigating 17β-estradiol-induced α-SMA accumulation and autophagy inhibition vi
GPNMB mitigates Alzheimer's disease and enhances autophagy via suppressing the mTOR signal.
Therapeutic potential of curcumin in autophagy modulation: Insights into the role of transcription factor EB.
Autophagy, aging, and age-related neurodegeneration.
LncRNA MIR155HG suppresses cell apoptosis by activating autophagy via miR-7036b-3p/GPNMB axis and AMPK/mTOR signaling in
Lithium Chloride Facilitates Autophagy Following Spinal Cord Injury via ERK-dependent Pathway.
Galantamine Inhibits Aβ1-42-Induced Neurotoxicity by Enhancing α7nAChR Expression as a Cargo Carrier for LC3 Binding and
Genetics, Mechanisms, and Therapeutic Progress in Polyglutamine Spinocerebellar Ataxias
Targeting α-Synuclein in Parkinson's Disease: Progress Towards the Development of Disease-Modifying Therapeutics.
Fisetin promotes ischemic flap survival by enhancing autophagy via inhibition of the PI3K/Akt/mTOR signaling pathway.
Vascular mimicry: Triggers, molecular interactions and in vivo models.
Class I phosphatidylinositol 3-kinase inhibitors for cancer therapy
Multidimensional autophagy nano-regulator boosts Alzheimer's disease treatment by improving both extra/intraneurona
Enhancement of oligodendrocyte autophagy alleviates white matter injury and cognitive impairment induced by chronic cere
Melatonin inhibits fibroblast cell functions and hypertrophic scar formation by enhancing autophagy through the MT2 rece
TRIM50 regulates Beclin 1 proautophagic activity.
Impaired autophagy in microglia aggravates dopaminergic neurodegeneration by regulating NLRP3 inflammasome activation in
MKP1 may be involved in the occurrence of depression by regulating hippocampal autophagy in rats.
Immunoblot-based assays for assessing autophagy in the turquoise killifish Nothobranchius furzeri.
Metformin attenuates atherosclerosis and plaque vulnerability by upregulating KLF2-mediated autophagy in apoE-/- mice.
GLP-1 analogue improves hepatic lipid accumulation by inducing autophagy via AMPK/mTOR pathway.
PVT1 alleviates hypoxia-induced endothelial apoptosis by enhancing autophagy via the miR-15b-5p/ATG14 and miR-424-5p/ATG
Psychological stress induces hair regenerative disorders through corticotropin-releasing hormone-mediated autophagy inhi
2-Methoxyestradiol protects against ischemia/reperfusion injury in alcoholic fatty liver by enhancing sirtuin 1-mediated
5-ALA localises to the autophagy compartment and increases its fluorescence upon autophagy enhancement through caloric r
Streptooctatin A induces autophagy and promotes α-synuclein clearance by directly binding to SUMO2 and inhibiting SUMOyl
Modulating autophagic flux via ROS-responsive targeted micelles to restore neuronal proteostasis in Alzheimer's dis
Translocator protein (TSPO) ligands attenuate mitophagy deficits in the SH-SY5Y cellular model of Alzheimer's disea
Targeting autophagy via mitochondrial uncoupling: Discovery of novel serratin derivative as a potential therapeutic for
Berberine attenuates apoptosis in rat retinal Müller cells stimulated with high glucose via enhancing autophagy and the
Neferine prevents autophagy induced by hypoxia through activation of Akt/mTOR pathway and Nrf2 in muscle cells.
Electrical stimulation at nanoscale topography boosts neural stem cell neurogenesis through the enhancement of autophagy
Effect and proposed mechanism of vitamin C modulating amino acid regulation of autophagic proteolysis.
Scoparone improves hepatic inflammation and autophagy in mice with nonalcoholic steatohepatitis by regulating the ROS/P3
Monotropein attenuates oxidative stress via Akt/mTOR-mediated autophagy in osteoblast cells.
d-Mannose suppresses osteoarthritis development in vivo and delays IL-1β-induced degeneration in vitro by enhancing auto
Autophagy inhibition and ferroptosis activation during atherosclerosis: Hypoxia-inducible factor 1α inhibitor PX-478 all
Matrine protects oligodendrocytes by inhibiting their apoptosis and enhancing mitochondrial autophagy.
Excessive Protein Accumulation and Impaired Autophagy in the Hippocampus of Angelman Syndrome Modeled in Mice.
Inhibition of Sirtuin 2 enhances autophagy and restores neuronal function in aged hippocampal neurons.
Casticin in cancer research: in vitro evidence and mechanistic insights into its antitumor potential.
Inhibition of miR-34a-5p alleviates hypoxia-reoxygenation injury by enhancing autophagy in steatotic hepatocytes.
Translating the biology of aging into novel therapeutics for Alzheimer disease
Propofol Inhibits HeLa Cells by Impairing Autophagic Flux via AMP-Activated Protein Kinase (AMPK) Activation and Endopla
Disrupting the interaction between AMBRA1 and DLC1 prevents apoptosis while enhancing autophagy and mitophagy.
Role of Hypoxia-Inducible Factors 1α (HIF1α) in SH-SY5Y Cell Autophagy Induced by Oxygen-Glucose Deprivation.
An AMPK-dependent regulatory pathway in tau-mediated toxicity.
Puerarin Attenuates Anoxia/Reoxygenation Injury Through Enhancing Bcl-2 Associated Athanogene 3 Expression, a Modulator
Increase in brain glycogen levels ameliorates Huntington's disease phenotype and rescues neurodegeneration in Droso
Metformin Enhances Functional Recovery of Peripheral Nerve in Rats with Sciatic Nerve Crush Injury.
Potentials of autophagy enhancing natural products in the treatment of Parkinson disease.
Targeting PI3K/AKT/mTOR-mediated autophagy for tumor therapy.
Parthenolide ameliorates bilirubin-induced neuronal cell injury by mediating autophagy.
Circ-FoxO3 alleviates APOE4-induced brain pathology through FoxO3-mediated autophagy.
Deconvoluting the relationships between autophagy and metastasis for potential cancer therapy.
Parkin Overexpression Ameliorates PrP106-126-Induced Neurotoxicity via Enhanced Autophagy in N2a Cells.
CD47 signaling in aging and age-related diseases: mechanisms, challenges, and therapeutic opportunities.
S-palmitoylation in ferroptosis: molecular mechanisms, modulators, and interplay with autophagy.
Harnessing the FOXO-SIRT1 axis: insights into cellular stress, metabolism, and aging.
BRI3 Orchestrates Lipid Metabolism and Autophagy in Glioblastoma: Implications for Tumor Cell Resilience.
Aging and age‐related diseases: from mechanisms to therapeutic strategies
Rapamycin Protects Sepsis-Induced Cognitive Impairment in Mouse Hippocampus by Enhancing Autophagy.
Pparα activation stimulates autophagic flux through lipid catabolism-independent route.
Autophagy Suppresses Ferroptosis by Degrading TFR1 to Alleviate Cognitive Dysfunction in Mice with SAE.
Hesperetin ameliorates mitochondrial dysfunction in acute kidney injury by mediating autophagy and inhibiting the cGAS-S
Genistein protects against ox-LDL-induced senescence through enhancing SIRT1/LKB1/AMPK-mediated autophagy flux in HUVECs
Curcumin promotes functional recovery after spinal cord injury by enhancing autophagic flux and attenuating apoptosis.
Enhanced Autophagy Contributes to Protective Effects of GM1 Ganglioside Against Aβ1-42-Induced Neurotoxicity and Cogniti
Exogenous CGRP Regulates Apoptosis and Autophagy to Alleviate Traumatic Brain Injury Through Akt/mTOR Signalling Pathway
Melatonin Enhances Autophagy and Reduces Apoptosis to Promote Locomotor Recovery in Spinal Cord Injury via the PI3K/AKT/
Role of AMPK in atherosclerosis via autophagy regulation.
Knockdown of miR-372 Inhibits Nerve Cell Apoptosis Induced by Spinal Cord Ischemia/Reperfusion Injury via Enhancing Auto
Parkin Protects Against Misfolded SOD1 Toxicity by Promoting Its Aggresome Formation and Autophagic Clearance.
The Neuroprotective Effect of Erythropoietin on Rotenone-Induced Neurotoxicity in SH-SY5Y Cells Through the Induction of
Chronic Exercise Protects Against Cognitive Deficits in an Alzheimer's Disease Model by Enhancing Autophagy and Red
Berberine can be a Potential Therapeutic Agent in Treatment of Huntington's Disease: A Proposed Mechanistic Insight
Tempol Mitigates Cisplatin-Induced Retinopathy by Modulating ER Stress, Enhancing Autophagy, and Preserving Neurotrophic
Mitochondria: the indispensable players in innate immunity and guardians of the inflammatory response
Metformin activates chaperone-mediated autophagy and improves disease pathologies in an Alzheimer disease mouse model
Triptonide Mediates Apoptosis and Autophagy via ROS/p38 MAPK Activation and mTOR/NF-κB Inhibition in Nasopharyngeal Carc
UFMylation: A Potential Modification for Neurological Diseases.
Inhibition of the P2Y2 Receptor Promotes Facial Nerve Function by Enhancing Neuron Autophagy.
Dermal Fibroblasts-derived Exosomes Alleviated Bronchopulmonary Dysplasia in Neonatal Rats Partially by Regulating Autop
Neuroprotective Strategies for Neurological Disorders by Natural Products: An update
Hydroxychloroquine Prevents High-altitude Cerebral Edema by Inhibiting Endothelial Claudin-5 Autophagic Degradation.
Cell Death Mechanisms in Stroke and Novel Molecular and Cellular Treatment Options
Role of Autophagy and Mitophagy in Neurodegenerative Disorders.
Therapeutic Applications of Natural Flavonoids Against Alzheimer's Disease-like Pathology: Special Focus on PI3K/Ak
Androgen receptor inhibition alleviated inflammation in experimental autoimmune myocarditis by increasing autophagy in m
Rifampicin Suppresses Amyloid-β Accumulation Through Enhancing Autophagy in the Hippocampus of a Lipopolysaccharide-Indu
TGM6 variants in Parkinson's disease: clinical findings and functional evidence.
Oxidative Stress, Synaptic Dysfunction, and Alzheimer’s Disease
The Amyloid-β Oligomer Hypothesis: Beginning of the Third Decade
Propionate alleviates palmitic acid-induced endoplasmic reticulum stress by enhancing autophagy in calf hepatic cells.
Effectiveness of Nicotinamide Phosphoribosyltransferase/Pre-B Cell Colony-enhancing Factor/Visfatin in preventing High G
PINK1, Parkin, and Mitochondrial Quality Control: What can we Learn about Parkinson’s Disease Pathobiology?
Luteolin and Exercise Combination Therapy Ameliorates Amyloid-β1-42 Oligomers-Induced Cognitive Impairment in AD Mice by
Protein Quality Control Pathways at the Crossroad of Synucleinopathies
Repurposing Drugs in Oncology (ReDO)—chloroquine and hydroxychloroquine as anti-cancer agents
Inhibition of miR-497 improves functional outcome after ischemic stroke by enhancing neuronal autophagy in young and age
Curcumin attenuates cognitive impairment by enhancing autophagy in chemotherapy.
Corrigendum to "Curcumin attenuates cognitive impairment by enhancing autophagy in chemotherapy" [Neurobiology
RIT2 regulates autophagy lysosomal pathway induction and protects against α-synuclein pathology in a cellular model of P
Role and molecular regulatory mechanisms of Hippo signaling pathway in Caenorhabditis elegans and mammalian cell models
Interplay of neuropeptide Y and autophagy in Alzheimer's disease: Therapeutic perspectives and mechanistic insights
Rapamycin ameliorates age-related hearing loss in C57BL/6J mice by enhancing autophagy in the SGNs.
Polysaccharide alleviates neurodegeneration and behavioral deficit by enhancing mitochondrial autophagy in chronic metha
Potential of plant-derived peptides for the improvement of memory and cognitive function.
Pseudoginsenoside-F11 reduces cognitive impairment and white matter injury in vascular dementia by alleviating autophagy
Autophagy in hemorrhagic stroke: Mechanisms and clinical implications.
Demethylzeylasteral ameliorates podocyte damage in murine lupus by inhibiting inflammation and enhancing autophagy.
Timosaponin B-II attenuates cerebral ischemia injury by enhancing Parkin-mediated mitophagy.
Stress endurance mediates the healthspan-promoting effect of two newly described iridoid glycosides from Verbascum nigru
Importance of ROS-mediated autophagy in determining apoptotic cell death induced by physapubescin B.
Blocking T-type calcium channels disrupts spermatogenesis in vivo and adversely affects spermatocytes in vitro by impair
The autophagy-NAD axis in longevity and disease.
Effects of long-term fluoride exposure on cognitive ability and the underlying mechanisms: Role of autophagy and its ass
Age-related macular degeneration and neurodegenerative disorders: Shared pathways in complex interactions.
The Autophagy-Lysosomal Pathway in Neurodegeneration: A TFEB Perspective.
Osthole protects H9c2 cardiomyocytes against trastuzumab-induced damage by enhancing autophagy through the p38MAPK/mTOR
Rifampicin attenuates rotenone-treated microglia inflammation via improving lysosomal function.
Autophagy activated by GR/miR-421-3p/mTOR pathway as a compensatory mechanism participates in chondrodysplasia induced b
Bovine parainfluenza type 3 virus induces incomplete autophagy to promote viral replication by activated beclin1 in vitr
The FoxO-Autophagy Axis in Health and Disease.
Inflammation as a central mechanism in Alzheimer's disease
The induction of AMPK-dependent autophagy leads to P53 degradation and affects cell growth and migration in kidney cance
Human endogenous retrovirus W family envelope protein (ERVWE1) regulates macroautophagy activation and micromitophagy in
Reducing lipofuscin accumulation and cardiomyocytic senescence of aging heart by enhancing autophagy.
Staying young at heart: autophagy and adaptation to cardiac aging.
Hernandezine promotes cancer cell apoptosis and disrupts the lysosomal acidic environment and cathepsin D maturation.
HSPB8 promoted intrahepatic cholangiocarcinoma progression by enhancing epithelial-mesenchymal transition and autophagy.
Increased expression of DRAM1 confers myocardial protection against ischemia via restoring autophagy flux.
The reduction of imidazole propionate induced by intermittent fasting promotes recovery of peripheral nerve injury by en
NVP-BEZ235 enhances autophagy and ameliorates cognitive deficits by targeting tauopathies.
Paeoniflorin alleviates depression by inhibiting the activation of NLRP3 inflammasome via promoting mitochondrial autoph
Alkaline Phosphatase and ATG4B Sequentially Activated Fluorescent Probe for Cancer Cell-Specific Live Imaging of Autopha
Advances in Plant Polysaccharides as Antiaging Agents: Effects and Signaling Mechanisms.
Autophagy Promotes Memory Formation.
Lycopene Regulates Macrophage Immune Response through the Autophagy Pathway Mediated by RIPK1.
Alginate-Derived Mannuronate Oligosaccharide Attenuates Tauopathy through Enhancing Autophagy.
Ginsenoside-Rh2 Promotes Functional Recovery after Spinal Cord Injury by Enhancing TFEB-Mediated Autophagy.
Conjugation with Phenylalanine Enhances Autophagy-Inducing Activity of (-)-Epigallocatechin Gallate in Hepatic Cells.
Designed Polymer Micelle for Clearing Amyloid Protein Aggregates via Up-Regulated Autophagy.
Dysregulation of Host Histone Acetylation by Acinetobacter baumannii: A Novel Mechanism for Autophagy Inhibition and Bac
Ferroptosis Induced by Pollutants: An Emerging Mechanism in Environmental Toxicology.
An Efficient Regioselective Synthesis of 8-Formylhomoisoflavonoids with Neuroprotective Activity by Enhancing Autophagy.
miR-873-5p Suppression Reinvigorates Aging Mesenchymal Stem Cells and Improves Cardiac Repair after Myocardial Infarctio
Rhynchophylla total alkaloid rescues autophagy, decreases oxidative stress and improves endothelial vasodilation in spon
Nuclear ULK1 promotes cell death in response to oxidative stress through PARP1.
The far-reaching scope of neuroinflammation after traumatic brain injury
Targeting phospholipase D in cancer, infection and neurodegenerative disorders
Corynoxine B derivative CB6 prevents Parkinsonian toxicity in mice by inducing PIK3C3 complex-dependent autophagy.
CDDO-Im ameliorates osteoarthritis and inhibits chondrocyte apoptosis in mice via enhancing Nrf2-dependent autophagy.
New therapeutics beyond amyloid-β and tau for the treatment of Alzheimer’s disease
Lonicerin promotes wound healing in diabetic rats by enhancing blood vessel regeneration through Sirt1-mediated autophag
Luteolin alleviates cognitive impairment in Alzheimer’s disease mouse model via inhibiting endoplasmic reticulum stress-
Exosomes derived from BMSCs ameliorate cyclophosphamide-induced testosterone deficiency by enhancing the autophagy of Le
Autophagy-targeting modulation to promote peripheral nerve regeneration.
Davunetide promotes structural and functional recovery of the injured spinal cord by promoting autophagy.
PSPH promotes colorectal cancer growth by triggering autophagy through AMPK-ULK1 activation and enhancing tumor immune e
Effects of stem cell therapy on preclinical stroke.
Resveratrol alleviates intestinal mucosal barrier dysfunction in dextran sulfate sodium-induced colitis mice by enhancin
Trehalose delays postmenopausal osteoporosis by enhancing AKT/TFEB pathway‑dependent autophagy flow in rats.
Dysregulated mTOR signaling in Alzheimer's disease: Linking pathogenic mechanisms to emerging therapeutic strategie
Current and Future Treatments in Alzheimer Disease: An Update
Obestatin attenuated methamphetamine-induced PC12 cells neurotoxicity via inhibiting autophagy and apoptosis.
Enhancing Lysosomal Activation Restores Neural Stem Cell Function During Aging.
Lifestyle factors and high-risk atherosclerosis: Pathways and mechanisms beyond traditional risk factors
Loss of Autophagy Causes Increased Apoptosis of Tibial Plateau Chondrocytes in Guinea Pigs with Spontaneous Osteoarthrit
Microglia TFEB activation attenuates Alzheimer's disease pathology by enhancing autophagy-lysosomal function.
The mitochondrial uncoupling effects of nitazoxanide enhances cellular autophagy and promotes the clearance of α-synucle
Melatonin modulates autophagy, mitochondria and antioxidant in the liver and brain of Perccottus glenni during recovery
microRNA-125b-1-3p mediates autophagy via the RRAGD/mTOR/ULK1 signaling pathway and mitigates atherosclerosis progressio
VMP1 enhances autophagy to mitigate cardiac fibroblast activation and reduce post-ischemia-reperfusion fibrosis.
HGF protected against diabetic nephropathy via autophagy-lysosome pathway in podocyte by modulating PI3K/Akt-GSK3β-TFEB
Triclosan-induced neuroinflammation develops caspase-independent and TNF-α signaling pathway associated necroptosis in N
Bisphenol A increases TLR4-mediated inflammatory response by up-regulation of autophagy-related protein in lung of adole
Effect of trehalose on mortality and disease severity in ICU-admitted patients: Protocol for a triple-blind, randomized,
Galangin alleviated myocardial ischemia-reperfusion injury by enhancing autophagic flux and inhibiting inflammation.
Mangiferin prevents diabetic nephropathy progression and protects podocyte function via autophagy in diabetic rat glomer
Pioglitazone protects tubular cells against hypoxia/reoxygenation injury through enhancing autophagy via AMPK-mTOR signa
Naringenin reduces oxidative stress and necroptosis, apoptosis, and pyroptosis in random-pattern skin flaps by enhancing
Novel prospects in targeting neurodegenerative disorders via autophagy.
Metformin attenuates diabetes-induced tau hyperphosphorylation in vitro and in vivo by enhancing autophagic clearance.
Restoring autophagy flux by rolipram attenuates ototoxicity in Hearing loss.
Saponins of Panax japonicus ameliorates cardiac aging phenotype in aging rats by enhancing basal autophagy through AMPK/
First evidence of the protective role of melatonin in counteracting cadmium toxicity in the rat ovary via the mTOR pathw
Dihydrolipoic acid enhances autophagy and alleviates neurological deficits after subarachnoid hemorrhage in rats.
SIRT1 suppresses cellular senescence and inflammatory cytokine release in human dermal fibroblasts by promoting the deac
Dexmedetomidine enhances Mitophagy via PINK1 to alleviate hippocampal neuronal Pyroptosis and improve postoperative cogn
Pramipexole improves cognitive deficits and synaptic plasticity impairments in 3xTg-AD mice through enhancing autophagy.
Clemastine attenuates AD-like pathology in an AD model mouse via enhancing mTOR-mediated autophagy.
Jujuboside A ameliorates high fat diet and streptozotocin induced diabetic nephropathy via suppressing oxidative stress,
Targeting LKB1-AMPK-SIRT1-induced autophagy and mitophagy pathways improves cerebrovascular homeostasis in APP/PS1 mice.
Cladrin alleviates dexamethasone-induced apoptosis of osteoblasts and promotes bone formation through autophagy inductio
Gefitinib facilitates PINK1/Parkin-mediated mitophagy by enhancing mitochondrial recruitment of OPTN.
Grass Carp Reovirus triggers autophagy enhancing virus replication via the Akt/mTOR pathway.
KDM1A-mediated upregulation of METTL3 ameliorates Alzheimer's disease via enhancing autophagic clearance of p-Tau t
Mito-Tempo suppresses autophagic flux via the PI3K/Akt/mTOR signaling pathway in neuroblastoma SH-SY5Y cells.
Quercetin attenuated ropivacaine-induced neurotoxicity in SH-SY5Y cells through upregulating Pim1 and enhancing autophag
Host immunity and intracellular bacteria evasion mechanisms: Enhancing host-directed therapies with drug delivery system
Orchestrating AMPK/mTOR signaling to initiate melittin-induced mitophagy: A neuroprotective strategy against Parkinson&#
Progesterone suppresses Aβ42-induced neuroinflammation by enhancing autophagy in astrocytes.
Kirenol attenuates pressure overload-induced heart failure by enhancing autophagy in macrophages.
Tau-Centric Targets and Drugs in Clinical Development for the Treatment of Alzheimer’s Disease
Role of ROS and RNS Sources in Physiological and Pathological Conditions
Intracerebral Hemorrhage, Oxidative Stress, and Antioxidant Therapy
Multifaceted Roles of GSK‐3 in Cancer and Autophagy‐Related Diseases
Recent Advances of the NLRP3 Inflammasome in Central Nervous System Disorders
Rutin as a Potent Antioxidant: Implications for Neurodegenerative Disorders
The Role of Oxidative Stress, Mitochondrial Function, and Autophagy in Diabetic Polyneuropathy
<i>Cannabis sativa</i> L. and Nonpsychoactive Cannabinoids: Their Chemistry and Role against Oxidative Stress, Inflammat
Current Research Therapeutic Strategies for Alzheimer’s Disease Treatment
Oxidant/Antioxidant Imbalance in Alzheimer’s Disease: Therapeutic and Diagnostic Prospects
Autophagy Modulation in Cancer: Current Knowledge on Action and Therapy
Neuroprotective Mechanisms of Resveratrol in Alzheimer’s Disease: Role of SIRT1
Electroacupuncture Preconditioning Improves Myocardial Infarction Injury via Enhancing AMPK-Dependent Autophagy in Rats.
Recent Insights into the Mitochondrial Role in Autophagy and Its Regulation by Oxidative Stress
The Role of the Antioxidant Response in Mitochondrial Dysfunction in Degenerative Diseases: Cross-Talk between Antioxida
Oxidative Stress-Mediated Blood-Brain Barrier (BBB) Disruption in Neurological Diseases
Beneficial Role of Phytochemicals on Oxidative Stress and Age-Related Diseases
Ginsenoside Rg1 Alleviates Podocyte EMT Passage by Regulating AKT/GSK3 β/β-Catenin Pathway by Restoring Autophagic Activ
Protective Effect of Metformin against Hydrogen Peroxide-Induced Oxidative Damage in Human Retinal Pigment Epithelial (R
Liraglutide, a TFEB-Mediated Autophagy Agonist, Promotes the Viability of Random-Pattern Skin Flaps.
Autophagy in Age-Related Macular Degeneration: A Regulatory Mechanism of Oxidative Stress.
Mesenchymal Stem Cells Attenuate Diabetic Lung Fibrosis via Adjusting Sirt3-Mediated Stress Responses in Rats.
Rapamycin Inhibited Pyroptosis and Reduced the Release of IL-1β and IL-18 in the Septic Response.
Fucoidan Inhibits NLRP3 Inflammasome Activation by Enhancing p62/SQSTM1-Dependent Selective Autophagy to Alleviate Ather
Ginkgolide B Protects Cardiomyocytes from Angiotensin II-Induced Hypertrophy via Regulation of Autophagy through SIRT1-F
Targeting Mitochondrial Biogenesis with Polyphenol Compounds
Gastrodin Promotes the Survival of Random-Pattern Skin Flaps via Autophagy Flux Stimulation.
Enriched Environment-Induced Neuroprotection against Cerebral Ischemia-Reperfusion Injury Might Be Mediated via Enhancin
Protective Effect of Photobiomodulation against Hydrogen Peroxide-Induced Oxidative Damage by Promoting Autophagy throug
Metformin Ameliorates D-Galactose-Induced Senescent Human Bone Marrow-Derived Mesenchymal Stem Cells by Enhancing Autoph
miR-149 Alleviates Ox-LDL-Induced Endothelial Cell Injury by Promoting Autophagy through Akt/mTOR Pathway.
Protective Effect of Keluoxin against Diabetic Nephropathy in Type 2 Diabetic Mellitus Models.
ADSCs Combined with Melatonin Promote Peripheral Nerve Regeneration through Autophagy.
Histone Deacetylase Inhibitors Reduce Cysts by Activating Autophagy in Polycystic Kidney Disease.
Protective Mechanism of Berberine on Human Retinal Pigment Epithelial Cells against Apoptosis Induced by Hydrogen Peroxi
Ischemic Preconditioning Alleviates Mouse Renal Ischemia/Reperfusion Injury by Enhancing Autophagy Activity of Proximal
Down-Regulation of Lncrna MALAT1 Attenuates Neuronal Cell Death Through Suppressing Beclin1-Dependent Autophagy by Regul
Dihydrotanshinone I Increase Amyloid-β Clearance and Decrease Tau Phosphorylation via Enhancing Autophagy.
AntimiR-30b Inhibits TNF-α Mediated Apoptosis and Attenuated Cartilage Degradation through Enhancing Autophagy.
Sestrin-Mediated Inhibition of Stress-Induced Intervertebral Disc Degradation Through the Enhancement of Autophagy.
Critical Reanalysis of the Mechanisms Underlying the Cardiorenal Benefits of SGLT2 Inhibitors and Reaffirmation of the N
Preliminary Study on Platelet-Rich Plasma Enhancing Autophagy Level and Promoting Hair Growth in Androgenetic Alopecia M
Cyclovirobuxine D Brain-Targeted Liposomes Improve Cerebral Ischemia-Reperfusion Injury via Anti-Oxidant Stress and Acti
microRNA-378 promotes autophagy and inhibits apoptosis in skeletal muscle.
Ablation of huntingtin in adult neurons is nondeleterious but its depletion in young mice causes acute pancreatitis
Therapeutic Strategy for Targeting Aggressive Malignant Gliomas by Disrupting Their Energy Balance
Reactive oxygen species trigger Parkin/PINK1 pathway–dependent mitophagy by inducing mitochondrial recruitment of Parkin
Novel therapeutic strategies for stroke: The role of autophagy.
Placenta-derived mesenchymal stem cells protect against diabetic kidney disease by upregulating autophagy-mediated SIRT1
SLC35D3 increases autophagic activity in midbrain dopaminergic neurons by enhancing BECN1-ATG14-PIK3C3 complex formation
TPT1 (tumor protein, translationally-controlled 1) negatively regulates autophagy through the BECN1 interactome and an M
Wild-type rabies virus induces autophagy in human and mouse neuroblastoma cell lines.
Autophagy impairment with lysosomal and mitochondrial dysfunction is an important characteristic of oxidative stress-ind
Emerging connections between RNA and autophagy.
Dietary spermidine for lowering high blood pressure.
Mask mitigates MAPT- and FUS-induced degeneration by enhancing autophagy through lysosomal acidification.
Anti- and pro-microbial roles of autophagy in plant-bacteria interactions.
HIPK3 modulates autophagy and HTT protein levels in neuronal and mouse models of Huntington disease.
Electroacupuncture ameliorates beta-amyloid pathology and cognitive impairment in Alzheimer disease via a novel mechanis
Phosphoproteome-based kinase activity profiling reveals the critical role of MAP2K2 and PLK1 in neuronal autophagy.
Proteasome dysfunction induces excessive proteome instability and loss of mitostasis that can be mitigated by enhancing
STYK1 promotes autophagy through enhancing the assembly of autophagy-specific class III phosphatidylinositol 3-kinase co
CDKN1B/p27 regulates autophagy via the control of Ragulator and MTOR activity in amino acid-deprived cells.
High-throughput screening of functional deubiquitinating enzymes in autophagy.
Autophagy-dependent regulation of skeletal muscle regeneration and strength by a RHOGEF.
Regorafenib induces lethal autophagy arrest by stabilizing PSAT1 in glioblastoma
Coronavirus interactions with the cellular autophagy machinery.
Treatments targeting autophagy ameliorate the age-related macular degeneration phenotype in mice lacking APOE (apolipopr
Stimulation of synaptic activity promotes TFEB-mediated clearance of pathological MAPT/Tau in cellular and mouse models
Regulation of LC3B levels by ubiquitination and proteasomal degradation.
Celastrol, a TFEB (transcription factor EB) agonist, is a promising drug candidate for Alzheimer disease.
Excitation-transcription coupling via synapto-nuclear signaling triggers autophagy for synaptic turnover and long-lastin
Targeting MCL1 to induce mitophagy is a potential therapeutic strategy for Alzheimer disease.
TTR (transthyretin) leads the autophagy disaster relief team against TARDBP/TDP-43 proteinopathy.
LYECs: lysosome-enhancing compounds as potential therapeutic approaches for Alzheimer disease.
Modeling Huntington disease through microRNA-mediated neuronal reprogramming identifies age-associated autophagy dysfunc
Optogenetic manipulation of lysosomal physiology and autophagic activity.
PINK1-dependent NFKB signaling contributes to amyloid pathology in Alzheimer disease.
Aerobic exercise attenuates autophagy-lysosomal flux deficits by ADRB2/β2-adrenergic receptor-mediated V-ATPase assembly
Involvement of acetylation of ATG4B in controlling autophagy induction.
CircEPS15, as a sponge of MIR24-3p ameliorates neuronal damage in Parkinson disease through boosting PINK1-PRKN-mediated
Enhancing neuronal reticulophagy: a strategy for combating aging and APP toxicity.
R406 and its structural analogs reduce SNCA/α-synuclein levels via autophagic degradation.
MCOLN/TRPML channels in the regulation of MTORC1 and autophagy.
TRIM27 elicits protective immunity against tuberculosis by activating TFEB-mediated autophagy flux.
HSPA8 regulates anti-bacterial autophagy through liquid-liquid phase separation.
Favorably against the odds - autophagy control despite advanced amyloid- ß toxicity.
Autophagy-enhancing strategies to promote intestinal viral resistance and mucosal barrier function in SARS-CoV-2 infecti
VAMP8 stabilization by DRAM1 enables autophagosome-lysosome fusion and promotes metastatic extravasation.
Shaping proteostasis at the cellular, tissue, and organismal level
Chaperone-Mediated Autophagy Regulates Hypoxic Pathology in Cardiomyocytes.
The deubiquitinase USP45 inhibits autophagy through actin regulation by Coronin 1B.
TRIMming down Mycobacterium tuberculosis replication: TRIM32 is required for bacterial ubiquitination and autophagy indu
lncRNA H19 promotes glioblastoma multiforme development by activating autophagy by sponging miR-491-5p.
Deacetylation of HSC70 by SIRT2 promotes chaperone mediated autophagy.
N-degron-mediated ATG8 isoform switching controls plant thermotolerance.
Vascular smooth muscle cell death, autophagy and senescence in atherosclerosis
Astragaloside IV attenuates IL-1β secretion by enhancing autophagy in H1N1 infection.
Riptortus pedestris effector induces autophagy through interaction with ATG8, enhancing insect feeding.
A novel and translational role for autophagy in antisense oligonucleotide trafficking and activity.
Cyclodextrin has conflicting actions on autophagy flux in vivo in brains of normal and Alzheimer model mice.
Role of gut microbiota and nutrients in amyloid formation and pathogenesis of Alzheimer disease
Metformin promotes angiogenesis by enhancing VEGFa secretion by adipose-derived stem cells via the autophagy pathway.
Melatonin pretreatment alleviates renal ischemia-reperfusion injury by promoting autophagic flux via TLR4/MyD88/MEK/ERK/
Lithium targeting of AMPK protects against cisplatin-induced acute kidney injury by enhancing autophagy in renal proxima
Nobiletin-mediated autophagy mitigates nanoplastic-induced toxicity in human intestinal Caco-2 cells.
The Effects of Metformin on Weight Loss, Cardiovascular Health, and Longevity.
Mood-stabilizing effects of rapamycin and its analog temsirolimus: relevance to autophagy.
Tamoxifen for amyotrophic lateral sclerosis: A randomized double-blind clinical trial.
Nitrate Promotes the Survival of Diabetic Skin Flaps by Enhancing Autophagy Through the AMPK Signaling Pathway.
C1q/TNF-Related Protein 9 Inhibits THP-1 Macrophage Foam Cell Formation by Enhancing Autophagy.
The Role of Psychological Stress on Heart Autophagy in Mice With Heart Failure.
Enhancing Autophagy Protects Against Sepsis-Induced Neuromuscular Dysfunction Associated with Qualitative Changes to Ace
Autophagy controls mesenchymal stem cell properties and senescence during bone aging.
Antagonizing peroxisome proliferator-activated receptor γ facilitates M1-to-M2 shift of microglia by enhancing autophagy
Poly (ADP-ribose) polymerase 1 inhibition prevents neurodegeneration and promotes α-synuclein degradation via transcript
Transcription factor EB enhances autophagy and ameliorates palmitate-induced insulin resistance at least partly via upre
Recent developments of HDAC inhibitors: Emerging indications and novel molecules
Methionine metabolism and methyltransferases in the regulation of aging and lifespan extension across species
AdipoRon promotes amyloid-β clearance through enhancing autophagy via nuclear GAPDH-induced sirtuin 1 activation in Alzh
Clemastine attenuates subarachnoid haemorrhage pathology in a mouse model via Nrf2/SQSTM1-mediated autophagy.
Activation of transient receptor potential vanilloid 1 ameliorates tau accumulation-induced synaptic damage and cognitiv
Stabilisation of PRCP by deubiquitinase-targeting chimera (DUBTAC) to replenish autophagy for ameliorating pathological
Hsa_circ_0072309 enhances autophagy and TMZ sensitivity in glioblastoma.
Inhibition of Salt-Inducible Kinase 2 Protects Motor Neurons From Degeneration in ALS by Activating Autophagic Flux and
Signaling pathways and defense mechanisms of ferroptosis
Compartment-Dependent Degradation of Mutant Huntingtin Accounts for Its Preferential Accumulation in Neuronal Processes.
G2019S-LRRK2 Expression Augments -Synuclein Sequestration into Inclusions in Neurons
Restoration of Sleep and Circadian Behavior by Autophagy Modulation in Huntington's Disease.
Leptin and leptin resistance in obesity: current evidence, mechanisms and future directions.
Autophagy-Induced Drug Resistance in Liver Cancer.
Health benefits of resveratrol administration
Arbutin inhibits inflammation and apoptosis by enhancing autophagy via SIRT1.
[Antidepressants as additional drugs for human brain gliomas].
Enhancing autophagy protects platelets in immune thrombocytopenia patients.
Decreased expression of adenosine receptor 2B confers cardiac protection against ischemia via restoring autophagic flux.
GOLPH3 promotes glioma progression by enhancing PHB2-mediated autophagy.
Osteopontin-integrin signaling positively regulates neuroplasticity through enhancing neural autophagy in the peri-infar
Sauchinone augments cardiomyocyte viability by enhancing autophagy proteins -PI3K, ERK(1/2), AMPK and Beclin-1 during ea
Tetrahydrocurcumin reduces oxidative stress-induced apoptosis via the mitochondrial apoptotic pathway by modulating auto
Triptolide Promotes the Clearance of α-Synuclein by Enhancing Autophagy in Neuronal Cells.
CORM-3 mitigates osteoarthritis by anti-inflammation and enhancing autophagy via inhibiting MAPK and mTOR pathways.
SKP-SCs transplantation alleviates 6-OHDA-induced dopaminergic neuronal injury by modulating autophagy.
Neuronal autosis is Na+/K+-ATPase alpha 3-dependent and involved in hypoxic-ischemic neuronal death.
Targeting ANXA7/LAMP5-mTOR axis attenuates spinal cord injury by inhibiting neuronal apoptosis via enhancing autophagy i
PIAS1 alleviates diabetic peripheral neuropathy through SUMOlation of PPAR-γ and miR-124-induced downregulation of EZH2/
Metformin protects retinal ganglion cells in a preclinical model of retinal ischemia/reperfusion injury and stabilizes v
Leucine regulates autophagy via acetylation of the mTORC1 component raptor.
Autophagy controls differentiation of Drosophila blood cells by regulating Notch levels in response to nutrient availabi
Intranasal drug delivery of small interfering RNA targeting Beclin1 encapsulated with polyethylenimine (PEI) in mouse br
Toxoplasma GRA16 attenuates Tau hyperphosphorylation and enhances autophagy in thrombin-treated HT-22 hippocampal neuron
Prominent action of butyrate over β-hydroxybutyrate as histone deacetylase inhibitor, transcriptional modulator and anti
2-Hydroxypropyl-gamma-cyclodextrin overcomes NPC1 deficiency by enhancing lysosome-ER association and autophagy.
Enhancing DOX efficacy against NSCLC through UDCA-mediated modulation of the TGF-β/MAPK autophagy pathways.
Molecular docking as a tool for the discovery of molecular targets of nutraceuticals in diseases management
Inhibition of autophagic flux differently modulates cannabidiol-induced death in 2D and 3D glioblastoma cell cultures.
Endosomal microautophagy is activated by specific cellular stresses in trout hepatocytes.
Nimbolide inhibits pancreatic cancer growth and metastasis through ROS-mediated apoptosis and inhibition of epithelial-t
The cellular adaptor GULP1 interacts with ATG14 to potentiate autophagy and APP processing.
CircCEMIP promotes anoikis-resistance by enhancing protective autophagy in prostate cancer cells.
Curcumin controls the senescence of adipose-derived mesenchymal stem cells via the FoxO3/autophagy signaling pathway to
LncRNA GTF3C1 promotes diabetic corneal wound healing by regulating GABARAP and PTEN to augment autophagy.
PINK1/PARKIN signalling in neurodegeneration and neuroinflammation
Melatonin alleviates senile osteoporosis by regulating autophagy and enhancing fracture healing in aged mice.
Sodium Orthovanadate Mitigates Nonalcoholic Fatty Liver Disease by Enhancing Autophagy.
Correction: Duhuo Jisheng Decoction regulates intracellular zinc homeostasis by enhancing autophagy via PTEN/Akt/mTOR pa
Safety, health improvement and well-being during a 4 to 21-day fasting period in an observational study including 1422 s
SlATG8f modulates tomato thermotolerance and fruit quality, correlating with changes in autophagy and heat shock-related
RTA408 alleviates retinal ganglion cells damage in mouse glaucoma by inhibiting excessive autophagy.
Autophagy regulates MK-2206-induced LDL receptor expression and cholesterol efflux pathways.
Effect of pyrroloquinoline quinone on skin aging in Bmi-1 KO mice and underlying mechanisms.
Life-Long Aerobic Exercise is a Non-Pharmacological Approach for Inducing Autophagy and Delaying Muscle Atrophy in the A
Metformin mitigates osteoarthritis progression by modulating the PI3K/AKT/mTOR signaling pathway and enhancing chondrocy
Clearance of cerebral Aβ in Alzheimer’s disease: reassessing the role of microglia and monocytes
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
Tau and neuroinflammation in Alzheimer’s disease: interplay mechanisms and clinical translation
APOE in the bullseye of neurodegenerative diseases: impact of the APOE genotype in Alzheimer’s disease pathology and bra
Molecular and cellular pathways contributing to brain aging
Protein misfolding and mitochondrial dysfunction in glaucoma.
Microglia and programmed cell death in spinal cord injury: beyond apoptosis.
Microglia in Alzheimer’s disease: pathogenesis, mechanisms, and therapeutic potentials
Small Heat Shock Proteins, Big Impact on Protein Aggregation in Neurodegenerative Disease
The comparative effectiveness of metformin and risperidone in a rat model of valproic acid-induced autism, Potential rol
Towards understanding mRNA-binding protein specificity: lessons from post-transcriptional regulation of ATG mRNA during
FUS pathology in ALS is linked to alterations in multiple ALS-associated proteins and rescued by drugs stimulating autop
The citrus flavonoid "Nobiletin" impedes STZ-induced Alzheimer's disease in a mouse model through regulat
Topical rapamycin reduces markers of senescence and aging in human skin: an exploratory, prospective, randomized trial
Mitochondrial Quality Control and Disease: Insights into Ischemia-Reperfusion Injury
Neuroprotective Autophagic Flux Induced by Hyperbaric Oxygen Preconditioning is Mediated by Cystatin C.
Metformin carbon nanodots promote odontoblastic differentiation of dental pulp stem cells by pathway of autophagy.
Assessing Autophagy in Muscle Stem Cells.
A heterozygous p.S143P mutation in LMNA associates with proteasome dysfunction and enhanced autophagy-mediated degradati
CHNQD-00603 Promotes Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells by the miR-452-3p-Mediated Autopha
Enhancing autophagy and energy metabolism in the meniscus can delay the occurrence of PTOA in ACLT rat.
Activating Transcription Factor-5 Knockdown Reduces Aggressiveness of Mammary Tumor Cells and Attenuates Mammary Tumor G
Autophagy Enhancing Contributes to the Organ Protective Effect of Alpha-Lipoic Acid in Septic Rats.
Autophagy and Host Defense in Nontuberculous Mycobacterial Infection
Targeting Microglial α-Synuclein/TLRs/NF-kappaB/NLRP3 Inflammasome Axis in Parkinson’s Disease
The lncRNA HOTAIRM1 regulates the degradation of PML-RARA oncoprotein and myeloid cell differentiation by enhancing the
HIV-1 Nef is released in extracellular vesicles derived from astrocytes: evidence for Nef-mediated neurotoxicity.
Oridonin induces autophagy via inhibition of glucose metabolism in p53-mutated colorectal cancer cells
PolyMetformin combines carrier and anticancer activities for in vivo siRNA delivery
Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis
mTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseases
Melatonin induces autophagy in neuroblastoma by alleviating Pak2‑mediated endoplasmic reticulum stress.
Atorvastatin reduces calcification in valve interstitial cells via the NF-κB signalling pathway by promoting Atg5-mediat
<i>Tremella fuciformis</i> polysaccharide: enhancing ischemic hypoxic adaptation of mesenchymal stem cells.
Metformin induces cell cycle arrest, apoptosis and autophagy through ROS/JNK signaling pathway in human osteosarcoma
Metformin in aging and aging-related diseases: clinical applications and relevant mechanisms
Mitochondrial Dysfunction as a Driver of Cognitive Impairment in Alzheimer’s Disease
Suffruticosol B Is an Osteogenic Inducer through Osteoblast Differentiation, Autophagy, Adhesion, and Migration.
Neuroprotection of Andrographolide against Neurotoxin MPP+-Induced Apoptosis in SH-SY5Y Cells via Activating Mitophagy,
Phosphorylated Tau in Alzheimer’s Disease and Other Tauopathies
Protective Effects of Ambroxol on Aβ and α-Synuclein-Induced Neurotoxicity Through Glucocerebrosidase Activation in HT-2
Bromodomain and Extraterminal Domain (BET) Protein Inhibition Hinders Glioblastoma Progression by Inducing Autophagy-Dep
Impact of Benzo(a)pyrene and Pyrene Exposure on Activating Autophagy and Correlation with Endoplasmic Reticulum Stress i
p.Phe508del-CFTR Trafficking: A Protein Quality Control Perspective Through UPR, UPS, and Autophagy.
Osthole Suppresses Knee Osteoarthritis Development by Enhancing Autophagy Activated via the AMPK/ULK1 Pathway.
Role of Autophagy on Heavy Metal-Induced Renal Damage and the Protective Effects of Curcumin in Autophagy and Kidney Pre
The Emerging Role of Autophagy as a Target of Environmental Pollutants: An Update on Mechanisms.
From Microcirculation to Aging-Related Diseases: A Focus on Endothelial SIRT1.
Pharmaceutical Agents for Targeting Autophagy and Their Applications in Clinics.
Autophagic Degradation of GPX4 Mediates Ferroptosis During Sheep Sperm Cryopreservation.
Puerarin promotes the viability and differentiation of MC3T3-E1 cells by enhancing LC3B-mediated autophagy through downr
KLF2 alleviates endothelial cell injury and inhibits the formation of THP‑1 macrophage‑derived foam cells by activating
Spermidine mitigates lipopolysaccharide-induced acute lung injury by enhancing autophagic flux.
Orexin A induces autophagy in HCT-116 human colon cancer cells through the ERK signaling pathway.
Formononetin may protect aged hearts from ischemia/reperfusion damage by enhancing autophagic degradation.
Chloroquine promotes gefitinib‑induced apoptosis by inhibiting protective autophagy in cutaneous squamous cell carcinoma
Critical Roles and Molecular Mechanisms of Chaperone-Mediated Autophagy in Infections.
Nanoparticles: Taking a Unique Position in Medicine
Therapeutic potential of natural medicines in diabetic kidney disease: restoring lipid homeostasis via lipophagy modulat
Pterostilbene attenuates osteoarthritis progression through p53-dependent autophagy activation: evidence from network an
Exploring bioactive phytochemicals as ULK1 activators for enhancing cytoprotective autophagy in amyotrophic lateral scle
Enhancing Autophagy Diminishes Aberrant Ca2+ Homeostasis and Arrhythmogenesis in Aging Rabbit Hearts.
Using Zebrafish to Dissect the Interaction of Mycobacteria with the Autophagic Machinery in Macrophages.
The Degradation of TMEM166 by Autophagy Promotes AMPK Activation to Protect SH-SY5Y Cells Exposed to MPP.
CXCR3 Inhibition Blocks the NF-κB Signaling Pathway by Elevating Autophagy to Ameliorate Lipopolysaccharide-Induced Inte
PLEKHM1 Overexpression Impairs Autophagy and Exacerbates Neurodegeneration in rAAV-α-Synuclein Mice.
Mitophagy in Parkinson’s Disease: From Pathogenesis to Treatment
The UPR preserves mature oligodendrocyte viability and function in adults by regulating autophagy of PLP.
Long non-coding RNA LINC00470 in serum derived exosome: a critical regulator for proliferation and autophagy in glioma c
CTCF-activated FUCA1 functions as a tumor suppressor by promoting autophagy flux and serum α-L-fucosidase serves as a po
Ceria-Zirconia nanoparticles reduce intracellular globotriaosylceramide accumulation and attenuate kidney injury by enha
The exosome journey: from biogenesis to uptake and intracellular signalling
Omega-3 polyunsaturated fatty acid attenuates traumatic brain injury-induced neuronal apoptosis by inducing autophagy th
TFE3 fusion proteins promote the progression of TFE3 rearranged renal cell carcinoma via enhancing chaperone-mediated li
Heat-killed probiotic Levilactobacillus brevis MKAK9 and its exopolysaccharide promote longevity by modulating aging hal
Alcohol-associated liver disease
The role of mitochondria in aging
Reduction of Spermine Synthase Suppresses Tau Accumulation Through Autophagy Modulation in Tauopathy.
Autophagy and Diabetic Encephalopathy: Mechanistic Insights and Potential Therapeutic Implications.
Inhibition of Drp1/Fis1 interaction slows progression of amyotrophic lateral sclerosis
HO-1 induced autophagy protects against IL-1 β-mediated apoptosis in human nucleus pulposus cells by inhibiting NF-κB.
Circular RNA EIF6 (Hsa_circ_0060060) sponges miR-144-3p to promote the cisplatin-resistance of human thyroid carcinoma c
Enhancing the retrograde axonal transport by curcumin promotes autophagic flux in N2a/APP695swe cells.
Role of FOXO1 in aldosterone-induced autophagy: a compensatory protective mechanism related to podocyte injury.
Salidroside Ameliorates Ultraviolet-Induced Keratinocyte Injury by Inducing SIRT1-Dependent Autophagy.
Melanin@PLGA/Nuciferine Nanoparticles for Enhanced Photothermal Therapy of Hepatocellular Carcinoma by Promoting Autopha
Oridonin Alleviates LPS-Induced Depression by Inhibiting NLRP3 Inflammasome via Activation of Autophagy.
Therapeutic Mechanisms of Berberine to Improve the Intestinal Barrier Function via Modulating Gut Microbiota, TLR4/NF-κ
TLR7 Stimulation With Imiquimod Induces Selective Autophagy and Controls Mycobacterium tuberculosis Growth in Mouse Macr
The role of ATG16L1 in Crohn's disease and the structural alteration mechanisms and functional consequences of the
Getah virus triggers ROS-mediated autophagy in mouse Leydig cells.
Role of mTOR-Regulated Autophagy in Synaptic Plasticity Related Proteins Downregulation and the Reference Memory Deficit
Enhancing autophagy mitigates LPS-induced neuroinflammation by inhibiting microglial M1 polarization and neuronophagocyt
Suppressor of Cytokine Signaling 2 Regulates Retinal Pigment Epithelium Metabolism by Enhancing Autophagy.
Usp14 down-regulation corrects sleep and circadian dysfunction of a Drosophila model of Parkinson's disease.
Regulation of adult neurogenesis: the crucial role of astrocytic mitochondria.
HMGB1 Promotes Resistance to Doxorubicin in Human Hepatocellular Carcinoma Cells by Inducing Autophagy via the AMPK/mTOR
Alisol A 24-Acetate and Alisol B 23-Acetate Induced Autophagy Mediates Apoptosis and Nephrotoxicity in Human Renal Proxi
GZ17-6.02 kills prostate cancer cells in vitro and in vivo.
Eugenol Attenuates Cerebral Ischemia-Reperfusion Injury by Enhancing Autophagy via AMPK-mTOR-P70S6K Pathway.
Pentapeptide Protects INS-1 Cells From hIAPP-Mediated Apoptosis by Enhancing Autophagy Through mTOR Pathway.
Catalpol Ameliorates Podocyte Injury by Stabilizing Cytoskeleton and Enhancing Autophagy in Diabetic Nephropathy.
Pterostilbene, An Active Constituent of Blueberries, Suppresses Proliferation Potential of Human Cholangiocarcinoma via
Pseudoginsenoside F11 Enhances the Viability of Random-Pattern Skin Flaps by Promoting TFEB Nuclear Translocation Throug
Traditional Chinese Medication Tongxinluo Attenuates Lipidosis in Ox-LDL-Stimulated Macrophages by Enhancing Beclin-1-In
Insights into the role of mitophagy in lung cancer: current evidence and perspectives.
Platelet derived growth factor promotes the recovery of traumatic brain injury by inhibiting endoplasmic reticulum stres
Bushen Huoxue formula attenuates lipid accumulation evoking excessive autophagy in premature ovarian insufficiency rats
Autophagy Inhibition Enhances the Anti-Tumor Activity of Methylseleninic Acid in Cisplatin-Resistance Human Lung Adenoca
Targeting autophagy: polydatin's role in inducing cell death in AML.
Neuroprotective Effects of Phosphodiesterase Inhibitors on Sestrin-2 (SESN2) Expression and Autophagy in Alzheimer'
Recent advances in the mechanisms of NLRP3 inflammasome activation and its inhibitors
Chronic Caffeine Treatment Protects Against α-Synucleinopathy by Reestablishing Autophagy Activity in the Mouse Striatum
Dexmedetomidine Alleviated Endoplasmic Reticulum Stress via Inducing ER-phagy in the Spinal Cord of Neuropathic Pain Mod
Dexmedetomidine Protects Against Lipopolysaccharide-Induced Acute Kidney Injury by Enhancing Autophagy Through Inhibitio
PI3K/AKT Signal Pathway: A Target of Natural Products in the Prevention and Treatment of Alzheimer’s Disease and Parkins
Hyperosmolarity-Induced Oxidative Stress Leads to Senescence in Human Corneal Epithelial Cells (HCEPC) via DNA Damage, M
Ketogenic Diet in Alzheimer’s Disease
LINC00470 represses cell autophagy and cisplatin sensitivity of glioma via suppressing PTEN expression.
Yun; Zhang, Wei
zhangweisdu@gmail.com
Early administration of trimetazidine attenuates diabetic cardiomyopathy in rats by alleviating fibrosis, reducing apopt
Viewdingdingdang9770@163.com
FGF21 augments autophagy in random-pattern skin flaps via AMPK signaling pathways and improves tissue survival.
xuehao@sdu.edu.cn
Hypoxic glioma-derived exosomes promote M2-like macrophage polarization by enhancing autophagy induction.
efzhang@zju.edu.cn
NEDD4L binds the proteasome and promotes autophagy and bortezomib sensitivity in multiple myeloma.
fuyang@zzu.edu.cn
CircSEC24B activates autophagy and induces chemoresistance of colorectal cancer via OTUB1-mediated deubiquitination of S
hf-liu@263.net
Regulation of TFEB activity and its potential as a therapeutic target against kidney diseases.
litao19850827@126.com
Exosomal circTGFBR2 promotes hepatocellular carcinoma progression via enhancing ATG5 mediated protective autophagy.
wanghua@ahmu.edu.cn
Autophagy deficiency promotes M1 macrophage polarization to exacerbate acute liver injury via ATG5 repression during agi
maocaiping@suda.edu.cn
LncRNA HOTAIR regulates autophagy and proliferation mechanisms in premature ovarian insufficiency through the miR-148b-3
yuding@fudan.edu.cn
Degradation of lipid droplets by chimeric autophagy-tethering compounds
sunjin@syphu.edu.cn
Engineered bacterial outer membrane vesicles encapsulating oncolytic adenoviruses enhance the efficacy of cancer virothe
linda.partridge@ucl.ac.uk
Enhancing autophagy by redox regulation extends lifespan in Drosophila.
albers.mark@mgh.harvard.edu
Machine learning identifies candidates for drug repurposing in Alzheimer’s disease
blume.yaroslav@nas.gov.ua
Autophagy formation, microtubule disorientation, and alteration of ATG8 and tubulin gene expression under simulated micr
laura.bonfili@unicam.it
Microbiota modulation counteracts Alzheimer’s disease progression influencing neuronal proteolysis and gut hormones plas
sbarmada@umich.edu
TDP43 nuclear export and neurodegeneration in models of amyotrophic lateral sclerosis and frontotemporal dementia
yurui@nbu.edu.cn
Sinularin induces autophagy-dependent cell death by activating ULK1 and enhancing FOXO3-ATG4A axis in prostate cancer ce
kimtwins72@catholic.ac.kr
HMGB1 mediated autophagy and apoptosis in human nucleus pulposus cells; chloroquine amplified apoptosis by inhibiting au
kimhyunjin@skku.edu
Two specific interactions of GATE16 with TRPML3 and RAB33B regulate autophagy.
jixuemeng@nankai.edu.cn
Radiosensitizing effects of Withaferin A in gastric cancer cells via autophagy Inhibition and mitochondrial disruption.
vellai@falco.elte.hu
The small molecule AUTEN-99 (autophagy enhancer-99) prevents the progression of neurodegenerative symptoms.
hhcheng@whu.edu.cn
The germline-enriched Ppp1r36 promotes autophagy.
shenlinghong@sjtu.edu.cn
Exercise-derived peptide confers protection against septic cardiomyopathy by enhancing CCAAT/enhancer binding protein β-
sxyangg@21cn.com
N4-acetylcytidine-mediated SOAT1 upregulation aggravates heart failure by inducing NCOA4-dependent ferroautophagy and fe
byan@njmu.edu.cn
Human Amniotic Mesenchymal Stromal Cells Promote Bone Regeneration via Regulating Ameloblastoma-Derived-Bone Marrow Mese
haoxj@mail.kib.ac.cn
Design of 20-deoxyingenol-esters-based PKC agonists and their lysosome biogenesis-enhancing activity.
jan.gunst@kuleuven.be
Toward nutrition improving outcome of critically ill patients: How to interpret recent feeding RCTs?
hubb@mail2.sysu.edu.cn
Resveratrol-βcd inhibited premature ovarian insufficiency progression by regulating granulosa cell autophagy.
xpzhou@xzhmu.edu.cn
YAP promotes autophagy and progression of gliomas via upregulating HMGB1.
brzhang@zju.edu.cn
Metformin attenuates plaque-associated tau pathology and reduces amyloid-β burden in APP/PS1 mice.
lihao1427@163.com
Modulation of PI3K/AKT/mTOR signaling pathway by combined stem cell and phytochemical treatment improves metabolic and r
chinsiokfong@ppukm.ukm.edu.my
Is targeting autophagy mechanism in cancer a good approach? The possible double-edge sword effect
zhengmg113@126.com
Trehalose enhances macrophage autophagy to promote myelin debris clearance after spinal cord injury.
waiho.tang@gwcmc.org
Exosomes: biogenesis, biologic function and clinical potential
lvlingchun@medmail.com.cn
Quercetin improves myocardial ischemia-reperfusion injury by regulating macrophage M2 polarization through Bcl-2/Beclin-
yztan@shmu.edu.cn
Growth differentiation factor 11 alleviates oxidative stress-induced senescence of endothelial progenitor cells via acti
m-Ala@student.tums.ac.ir
Sestrin2 in cancer: a foe or a friend?
zhangdongliang@mail.ccmu.edu.cn
Puerarin relives inflammation, bone destruction and facilitates osteogenic differentiation in periodontitis by enhancing
jianghai0318@163.com
METTL21C mediates autophagy and formation of slow-twitch muscle fibers in mice after exercise.
amylo@hku.hk
Lutein Attenuates Both Apoptosis and Autophagy upon Cobalt (II) Chloride-Induced Hypoxia in Rat Műller Cells.
huqin@shsmu.edu.cn.
Mitochondria in Ischemic Stroke: New Insight and Implications
bhuang@ahau.edu.cn
Acetylation dynamics of MrATG4 governing autophagy-mediated conidiation in an entomopathogenic fungus.
ionyango@genciabiotech.com
Mitochondrial Dysfunction in Alzheimer’s Disease and the Rationale for Bioenergetics Based Therapies
yaozhaohui2004@126.com.
TBC1D15 Inhibits Autophagy of Microglia through Maintaining the Damaged Swelling Lysosome in Alzheimer's Disease.
marco.cordani@imdea.org
Targeting autophagy using metallic nanoparticles: a promising strategy for cancer treatment
eran.elinav@weizmann.ac.il
Inflammasome activation and regulation: toward a better understanding of complex mechanisms
e.f.fang@medisin.uio.no
Amelioration of Alzheimer’s disease pathology by mitophagy inducers identified via machine learning and a cross-species
gaojiehighclea@smmu.edu.cn
Autophagy-modulating biomaterials: multifunctional weapons to promote tissue regeneration.
jintai_yu@fudan.edu.cn
Tauopathies: new perspectives and challenges
Christopher.Morrone@camh.ca
Proteostasis failure exacerbates neuronal circuit dysfunction and sleep impairments in Alzheimer's disease.
i.rea@qub.ac.uk
Age and Age-Related Diseases: Role of Inflammation Triggers and Cytokines
gcenini@gmail.com
Mitochondria as Potential Targets in Alzheimer Disease Therapy: An Update
tsmin@jejunu.ac.kr
Nanocurcumin: A Promising Candidate for Therapeutic Applications
lin_wang@hust.edu.cn
The Role of NLRP3 Inflammasome in Alzheimer’s Disease and Potential Therapeutic Targets
gbstokin@alumni.ucsd.edu
Neuroinflammation in Alzheimer’s Disease
alexander.bartelt@med.uni-muenchen.de
Cardiac proteostasis in obesity and cardiovascular disease.
M.Cordeiro@ucl.ac.uk
Glaucoma: the retina and beyond
r.sullivan@ucl.ac.uk
Spinocerebellar ataxia: an update
shubinguo@126.com
ATGL deficiency aggravates pressure overload-triggered myocardial hypertrophic remodeling associated with the proteasome
yangye876@sina.com
Echinacoside protects against MPTP/MPP+-induced neurotoxicity via regulating autophagy pathway mediated by Sirt1.
rritzel@som.umaryland.edu
Functional and transcriptional profiling of microglial activation during the chronic phase of TBI identifies an age-rela
mitoma@tokyo-med.ac.jp
Consensus Paper. Cerebellar Reserve: From Cerebellar Physiology to Cerebellar Disorders.
p.noisa@sut.ac.th
Cannabidiol Enhances SIRT1 and Autophagy for the Maintenance of Human Mesenchymal Stem Cells.
ckumsta@sbpdiscovery.org
Monitoring Autophagy in Human Aging: Key Cell Models and Insights.
rgzhai@uchicago.edu
Regulation of proteostasis by sleep through autophagy in Drosophila models of Alzheimer's disease.
zhangmt66@ustc.edu.cn
Lamotrigine Enhances Autophagy and Reduces Post-Traumatic Spinal Neural Injury in Mice.
yechenyi@zju.edu.cn
Upregulation of Parkin Accelerates Osteoblastic Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells and Bone R
ludan.2007@163.com
Inhibition of PDE1-B by Vinpocetine Regulates Microglial Exosomes and Polarization Through Enhancing Autophagic Flux for
Drqi@163.com
Doxorubicin induces cardiotoxicity by enhancing autophagy via mTOR signaling in hiPSC- and hESC-derived cardiomyocytes.
xli3@umc.edu
Direct Cardiac Actions of Sodium-Glucose Cotransporter 2 Inhibition Improve Mitochondrial Function and Attenuate Oxidati
zhaoheyong@126.com
LRP6 Knockdown Ameliorates Insulin Resistance via Modulation of Autophagy by Regulating GSK3β Signaling in Human LO2 Hep
mtan@health.southalabama.edu
Diverse Roles of Mitochondria in Immune Responses: Novel Insights Into Immuno-Metabolism
tavernarakis@imbb.forth.gr
The Role of Mitophagy in Innate Immunity
qianyang@fmmu.edu.cn
Regulation of ER stress-induced autophagy by GSK3β-TIP60-ULK1 pathway.
angela.rizzo@ifo.gov.it
Pharmacological activation of SIRT6 triggers lethal autophagy in human cancer cells.
weitang@sdu.edu.cn
PGRN acts as a novel regulator of mitochondrial homeostasis by facilitating mitophagy and mitochondrial biogenesis to pr
drjinzj@163.com
Apatinib-induced protective autophagy and apoptosis through the AKT–mTOR pathway in anaplastic thyroid cancer
bin.xie@kennedy.ox.ac.uk
Sirt3 suppresses calcium oxalate-induced renal tubular epithelial cell injury via modification of FoxO3a-mediated autoph
angelo.poletti@unimi.it
Dual role of autophagy on docetaxel-sensitivity in prostate cancer cells.
ghu@njmu.edu.cn
The effect of fluoxetine on astrocyte autophagy flux and injured mitochondria clearance in a mouse model of depression.
pengwenna@csu.edu.cn
Platelet rich plasma alleviates OGD/R injury in N2a cell by enhancing autophagy through the miR‑223/PAQR3 pathway.
meijinyu@ahmu.edu.cn
Shufengjiedu capsules protect against neuronal loss in olfactory epithelium and lung injury by enhancing autophagy in ra
psong@it.ncgm.go.jp
A circadian rhythm-restricted diet regulates autophagy to improve cognitive function and prolong lifespan.
shenm2015@njau.edu.cn.
FOXO1-mediated nuclear sequestration of STAT3 and AKT1 triggers FOXO3-dependent autophagic death in hypoxic granulosa ce
hu.lijuan@zs-hospital.sh.cn
SIRT6 ameliorates LPS-induced apoptosis and tight junction injury in ARDS through the ERK1/2 pathway and autophagy.
xuli@cmu.edu.cn.
Ursolic Acid Alleviates Mitotic Catastrophe in Podocyte by Inhibiting Autophagic P62 Accumulation in Diabetic Nephropath
chensmalldragon@163.com
Heterophyllin B enhances transcription factor EB-mediated autophagy and alleviates pyroptosis and oxidative stress after
jiahonglu@um.edu.mo
Enhancing autophagy maturation with CCZ1-MON1A complex alleviates neuropathology and memory defects in Alzheimer disease
qinyueqiu@ymun.edu.cn
Unlocking the Therapeutic Potential: Harnessing miR-125a-5p To Enhance Autophagy and Apoptosis in Pancreatic Cancer thro
huixie@csu.edu.cn
Inhibition of miR-331-3p and miR-9-5p ameliorates Alzheimer's disease by enhancing autophagy.
andrea.rasola@unipd.it
Hexokinase 2 in Cancer: A Prima Donna Playing Multiple Characters
fengzh@cinj.rutgers.edu
The Regulation of Ferroptosis by Tumor Suppressor p53 and its Pathway
ines.ripa@cbm.csic.es
Interplay between Autophagy and Herpes Simplex Virus Type 1: ICP34.5, One of the Main Actors.
schachner@dls.rutgers.edu
Functional Relationships between L1CAM, LC3, ATG12, and Aβ.
yhni@ntu.edu.tw
Tat-Beclin-1 Peptide Ameliorates Metabolic Dysfunction-Associated Steatotic Liver Disease by Enhancing Hepatic Autophagy
eesposito@unime.it
CK and LRRK2 Involvement in Neurodegenerative Diseases.
zhuxujun@njau.edu.cn
Interaction Between CsATG8f and CsRAP2.12 Modulates Antioxidant Defense and Hypoxia Response During Submergence in Camel
zhangzhidong@swun.edu.cn
Non-Structural Protein V of Canine Distemper Virus Induces Autophagy via PI3K/AKT/mTOR Pathway to Facilitate Viral Repli
schlett.katalin@ttk.elte.hu
Comparative Analysis of Two Autophagy-Enhancing Small Molecules (AUTEN-67 and -99) in a Drosophila Model of Spinocerebel
anazambrano17@hotmail.com
Molecular Mechanisms and Therapeutic Perspectives of Gut Microbiota, Autophagy, and Apoptosis in Cholangiocarcinoma Path
hongyu@hznu.edu.cn
Conditional Overexpression of Neuritin in Supporting Cell Protects Cochlear Hair Cell and Delays Age-Related Hearing Los
wenzhang1968@163.com
Cholestane-3β,5α,6β-triol Induces Multiple Cell Death in A549 Cells via ER Stress and Autophagy Activation.
zhoup0520@163.com
Inhibitory Effects of Ginsenoside Rb1 on Early Atherosclerosis in ApoE-/- Mice via Inhibition of Apoptosis and Enhancing
dingfei@ntu.edu.cn
Pyrroloquinoline Quinone Inhibits Rotenone-Induced Microglia Inflammation by Enhancing Autophagy.
kouxianjuan@126.com
Nutraceutical or Pharmacological Potential of Moringa oleifera Lam.
Arunas.Savickas@lsmuni.lt
Flavonoids as Anticancer Agents
choidk@kku.ac.kr
Dioscin-Mediated Autophagy Alleviates MPP+-Induced Neuronal Degeneration: An In Vitro Parkinson's Disease Model.
agata.poniewierska-baran@usz.edu.pl
Resveratrol, Piceatannol, Curcumin, and Quercetin as Therapeutic Targets in Gastric Cancer-Mechanisms and Clinical Impli
xuxy53@mail2.sysu.edu.cn
Bioactivity, Health Benefits, and Related Molecular Mechanisms of Curcumin: Current Progress, Challenges, and Perspectiv
chinkokyong@ppukm.ukm.edu.my
Therapeutic Effects of Olive and Its Derivatives on Osteoarthritis: From Bench to Bedside.
shanzhongguo@nwafu.edu.cn
Diosgenin Targets CaMKK2 to Alleviate Type II Diabetic Nephropathy through Improving Autophagy, Mitophagy and Mitochondr
trangnguyen@khu.ac.kr
Autophagy-Enhancing Properties of Hedyotis diffusa Extracts in HaCaT Keratinocytes: Potential as an Anti-Photoaging Cosm
renatanowak@umlub.pl
Biological Activity of Berberine—A Summary Update
jhsheng@zju.edu.cn
5'-tiRNA-Lys maintains intestinal epithelial homeostasis by EWSR1-dependent suppression of miR-125a and autophagy a
panrong_0131@126.com
Ononin alleviates H2O2-induced cardiomyocyte apoptosis and improves cardiac function by activating the AMPK/mTOR/autopha
pyang@jlu.edu.cn
Rapamycin regulates the balance between�cardiomyocyte apoptosis and autophagy in chronic heart failure by inhibiting mTO
dengzhouming@foxmail.com
AMP-activated protein kinase stimulates osteoblast differentiation and mineralization through autophagy induction.
yjyangjj@126.com
Larixyl acetate, a TRPC6 inhibitor, attenuates pressure overload‑induced heart failure in mice.
zacharyzhou@suda.edu.cn
Vitamin D induces autophagy of pancreatic β-cells and enhances insulin secretion.
changlongli@scu.edu.cn
Rapamycin promotes the anticancer action of dihydroartemisinin in breast cancer MDA-MB-231 cells by regulating expressio
rashad_hussain@urmc.rochester.edu
Neurodegenerative Diseases: Regenerative Mechanisms and Novel Therapeutic Approaches
A.Mueller@med.uni-muenchen.de
Recent Advances in Understanding the Pathogenesis of Rheumatoid Arthritis: New Treatment Strategies
ttian@bjtu.edu.cn
mTOR Signaling in Cancer and mTOR Inhibitors in Solid Tumor Targeting Therapy
mvbulck@iib.uam.es
Novel Approaches for the Treatment of Alzheimer’s and Parkinson’s Disease
balbensi@sbrc.ca
Alzheimer’s Disease Pathogenesis: Role of Autophagy and Mitophagy Focusing in Microglia
md.rezaulislam100ds@gmail.com
Role of Phenolic Compounds in Human Disease: Current Knowledge and Future Prospects
caizhiyou@ucas.ac.cn
Role of AMPK in autophagy.
hhuang@mail.ncyu.edu.tw
Intra-Articular Injection of (-)-Epigallocatechin 3-Gallate to Attenuate Articular Cartilage Degeneration by Enhancing A
duliyin2016@163.com
Estrogen Regulates Glucose Metabolism in Cattle Neutrophils Through Autophagy.
lxiang@zju.edu.cn
Arctigenin from Fructus arctii Exhibits Antiaging Effects via Autophagy Induction, Antioxidative Stress, and Increase in
qijianhua@zju.edu.cn
Procyanidin A1 from Peanut Skin Exerts Anti-Aging Effects and Attenuates Senescence via Antioxidative Stress and Autopha
Roberto.Bernabei@unicatt.it
Mitochondrial Dysfunction, Oxidative Stress, and Neuroinflammation: Intertwined Roads to Neurodegeneration
ruiwang@yorku.ca
Hydrogen Sulfide (H2S) Metabolism, Iron Overload, and Apoptosis-Autophagy Equilibrium in Vascular Smooth Muscle Cells.
taketani@tokushima-u.ac.jp
Identification of Dietary Phytochemicals Capable of Enhancing the Autophagy Flux in HeLa and Caco-2 Human Cell Lines.
jfuentes@unex.es
Role of TFEB in Huntington's Disease.
huang817@cgmh.org.tw
Therapeutic Potential of Nutritional Aryl Hydrocarbon Receptor Ligands in Gut-Related Inflammation and Diseases.
litie@ccucm.edu.cn
The Mechanism of Acupuncture Regulating Autophagy: Progress and Prospect.
jixiong.xu@ncu.edu.cn
Mesenchymal Stem Cell-Derived Exosomes miR-143-3p Attenuates Diabetic Kidney Disease by Enhancing Podocyte Autophagy via
aalattar@ut.edu.sa
Computational and Experimental Approaches Exploring the Role of Hesperetin in Improving Autophagy in Rat Diabetic Retino
d.cervia@unitus.it
Pathological Defects in a Drosophila Model of Alzheimer's Disease and Beneficial Effects of the Natural Product Lis
david.romeo-guitart@inserm.fr
Endogenous Mechanisms of Neuroprotection: To Boost or Not to Boost.
liuw079@csu.edu.cn
Reversal of Myofibroblast Apoptosis Resistance and Collagen Deposition by Phaseoloidin-Induced Autophagy Attenuates Pulm
alessandra.ferraresi@med.uniupo.it
Cancer-Associated Fibroblast-Derived IL-6 Determines Unfavorable Prognosis in Cholangiocarcinoma by Affecting Autophagy-
nicoletta.bianchi@unife.it
Molecular Mechanisms of Drug Resistance in Clear Cell Renal Cell Carcinoma.
Erinna.Lee@latrobe.edu.au
BECLIN1: Protein Structure, Function and Regulation
yzhu@suda.edu.cn
Activation of Nrf2 in Astrocytes Suppressed PD-Like Phenotypes via Antioxidant and Autophagy Pathways in Rat and Drosoph
hozawa@tohoku-mpu.ac.jp
Chaperone-Mediated Autophagy in Neurodegenerative Diseases and Acute Neurological Insults in the Central Nervous System.
sukumaran@uthscsa.edu
Calcium Signaling Regulates Autophagy and Apoptosis
Stefan.Ryter@proterris.com
Heme Oxgenase-1, a Cardinal Modulator of Regulated Cell Death and Inflammation.
laura.j.smith@ucl.ac.uk
GBA Variants and Parkinson Disease: Mechanisms and Treatments
dutta.shamit@mayo.edu
Structural and Functional Perspectives of Optineurin in Autophagy, Immune Signaling, and Cancer.
yongweon_yi@dankook.ac.kr
From Orange to Oncology: Anti-Inflammatory and Anti-Cancer Mechanisms of Sinensetin
safwa.sorour@fmed.bu.edu.eg
Mesenchymal Stem Cell-Derived Exosomes Ameliorated Diabetic Nephropathy by Autophagy Induction through the mTOR Signalin
mkusaczuk@wp.pl
Tauroursodeoxycholate—Bile Acid with Chaperoning Activity: Molecular and Cellular Effects and Therapeutic Perspectives
hcyang@mail.ypu.edu.tw
The Redox Role of G6PD in Cell Growth, Cell Death, and Cancer
cwang@ocean.ag
Autophagy in Chronic Kidney Diseases
Sarika_Srivastava@vtc.vt.edu
The Mitochondrial Basis of Aging and Age-Related Disorders
wuw21@lzu.edu.cn
Ghrelin in Focus: Dissecting Its Critical Roles in Gastrointestinal Pathologies and Therapies.
hjkang90@unist.ac.kr
TonEBP Promotes β-Cell Survival under ER Stress by Enhancing Autophagy.
a.sierra@ikerbasque.org
Autophagy and Microglia: Novel Partners in Neurodegeneration and Aging
antonio.palumbopiccionello@unipa.it
Heat Shock Proteins in Alzheimer’s Disease: Role and Targeting
lees@inha.ac.kr
Autophagy in Neurodegenerative Diseases: A Hunter for Aggregates
r.martins@ecu.edu.au
Activate or Inhibit? Implications of Autophagy Modulation as a Therapeutic Strategy for Alzheimer's Disease.
katja.badanjak@uni.lu
The Contribution of Microglia to Neuroinflammation in Parkinson’s Disease
kunnumakkara@iitg.ac.in
Targeting AKT/mTOR in Oral Cancer: Mechanisms and Advances in Clinical Trials
zhixiangxu@fudan.edu.cn.
HSPB2 facilitates neural regeneration through autophagy for sensorimotor recovery after traumatic brain injury.
leimsh@163.com
Salidroside protects endothelial cells against LPS-induced inflammatory injury by inhibiting NLRP3 and enhancing autopha
huakeqinjiaoshou1@126.com
Elevated VAMP8 expression promotes cervical cancer progression by enhancing autophagy via HIF-1 pathway.
fuhailong1979@163.com
Huc-MSCs-derived exosomes attenuate inflammatory pain by regulating microglia pyroptosis and autophagy via the miR-146a-
wangyefu@whu.edu.cn
Integral membrane protein 2A inhibits cell growth in human breast cancer via enhancing autophagy induction.
rjshenying8@163.com
Promoting collateral formation in type 2 diabetes mellitus using ultra-small nanodots with autophagy activation and ROS
shenyanping@suda.edu.cn
Isoginkgetin-loaded reactive oxygen species scavenging nanoparticles ameliorate intervertebral disc degeneration via enh
wangxiumei75@aliyun.com
HAS-CIRCpedia-5280 sponges miR-4712-5p inhibited colon cancer autophagyinduced by human beta-defensin-1.
Juergen.Fritsch@ukr.de
Loss of ADAM15 prevents necroptosis induction by partial RIPK1 degradation due to enhanced TNF-R1 surface expression and
yangxl28@mail.sysu.edu.cn
Targeting RPA promotes autophagic flux and the antitumor response to radiation in nasopharyngeal carcinoma.
liqunjiao@sina.cn
Annexin A1 protects against cerebral ischemia–reperfusion injury by modulating microglia/macrophage polarization via FPR
fengxiaojun@ahmu.edu.cn
Transcranial direct current stimulation exerts neuroprotective effects in Parkinson's disease by restoring Mlst8-me
xiongbo@zju.edu.cn
Supplementation of spermidine enhances the quality of postovulatory aged porcine oocytes.
wangdongdong@sdu.edu.cn
Pbk positively regulates myoblast differentiation and muscle regeneration via enhancing AMPK/ULK1 mediated myogenic auto
caoyang@mail.sysu.edu.cn
Klotho enhances bone regenerative function of hPDLSCs via modulating immunoregulatory function and cell autophagy.
zhaopeng871@126.com
Bufei Yishen formula protects the airway epithelial barrier and ameliorates COPD by enhancing autophagy through the Sirt
GonzalesM20@uthscsa.edu.
Biological aging processes underlying cognitive decline and neurodegenerative disease
saeid.ghavami@umanitoba.ca
Unlocking a New Path: An Autophagometer that Measures Flux Using a Non-Fluorescent Immunohistochemistry Method.
steve.finkbeiner@gladstone.ucsf.edu
The Autophagy Lysosomal Pathway and Neurodegeneration
cetosta@unb.br
The adaptation of SARS-CoV-2 to humans.
linxianchu@zjsmyy.com
KLF5 Alleviates Excessive Autophagy-Induced Podocyte Injury by Enhancing ITCH-Mediated Ubiquitination of ACTR2.
fanjin@njmu.edu.cn
Neural stem cell small extracellular vesicle-based delivery of 14-3-3t reduces apoptosis and neuroinflammation following
jialiudl@aliyun.com
Lumbar puncture-administered resveratrol inhibits STAT3 activation, enhancing autophagy and apoptosis in orthotopic rat
yangxs@dlmedu.edu.cn
Deglycosylated EpCAM regulates proliferation by enhancing autophagy of breast cancer cells via PI3K/Akt/mTOR pathway.
budanova@tcd.ie
Sesn-1 is required for lifespan extension during caloric deprivation in C. elegans through inhibition of mTORC1 and acti
wdle@sibs.ac.cn
Advances in autophagy for Parkinson's disease pathogenesis and treatment.
jingzhao@sdu.edu.cn
The ROS/NF-κB/NR4A2 pathway is involved in H2O2 induced apoptosis of resident cardiac stem cells via autophagy.
zwsun@ccmu.edu.cn
Amorphous silica nanoparticles trigger vascular endothelial cell injury through apoptosis and autophagy via reactive oxy
zxxie@whu.edu.cn
Inhibition of autophagy contributes to the toxicity of cadmium telluride quantum dots in Saccharomyces cerevisiae.
duanruicpu@163.com
AVE 0991 Suppresses Astrocyte-Mediated Neuroinflammation of Alzheimer's Disease by Enhancing Autophagy.
hwanwoopark@konyang.ac.kr
Hepatocyte-Targeted Epicatechin Nanoparticles Promote Autophagy and Enhance Mitochondrial Function in Metabolic Dysfunct
agnieszka.lukomska@wum.edu.pl
Dual role of complement in neuronal repair.
limin@hkbu.edu.hk
Bromo-protopine, a novel protopine derivative, alleviates tau pathology by activating chaperone-mediated autophagy for A
bdtao@cmu.edu.cn
Updated insights into the NLRP3 inflammasome in postoperative cognitive dysfunction: emerging mechanisms and treatments.
lengyf@lzu.edu.cn
Propofol Ameliorates ox-LDL-Induced Endothelial Damage Through Enhancing Autophagy via PI3K/Akt/m-TOR Pathway: A Novel T
ligenmo@163.com
Autophagy regulates inflammation in intracerebral hemorrhage: Enemy or friend?
kongliang0115@126.com
TIGAR Attenuates High Glucose-Induced Neuronal Apoptosis via an Autophagy Pathway.
stabdullah@iiim.res.in
Pharmacological Activation of Autophagy Restores Cellular Homeostasis in Ultraviolet-(B)-Induced Skin Photodamage.
zhangju@nankai.edu.cn
The HeyL-Aromatase Axis Promotes Cancer Stem Cell Properties by Endogenous Estrogen-Induced Autophagy in Castration-Resi
Luhy@zjcc.org.cn
Role of Borneol Induced Autophagy in Enhancing Radiosensitivity of Malignant Glioma.
abbes.belkhiri@vanderbilt.edu
AXL Promotes Metformin-Induced Apoptosis Through Mediation of Autophagy by Activating ROS-AMPK-ULK1 Signaling in Human E
jinyangtmmu@sina.com
RAC3 Inhibition Induces Autophagy to Impair Metastasis in Bladder Cancer Cells via the PI3K/AKT/mTOR Pathway.
yij@lzu.edu.cn
Parthenolide and arsenic trioxide co-trigger autophagy-accompanied apoptosis in hepatocellular carcinoma cells.
Jun.Hou@hli.ubc.ca
Mangiferin Enhanced Autophagy via Inhibiting mTORC1 Pathway to Prevent High Glucose-Induced Cardiomyocyte Injury.
drqiubo@sohu.com
Mingmu Xiaomeng Tablets Restore Autophagy and Alleviate Diabetic Retinopathy by Inhibiting PI3K/Akt/mTOR Signaling.
yuls@zju.edu.cn
The Drug-Resistance Mechanisms of Five Platinum-Based Antitumor Agents
xupeng@gzucm.edu.cn
Sanqi Oral Solution Ameliorates Renal Ischemia/Reperfusion Injury via Reducing Apoptosis and Enhancing Autophagy: Involv
changbc1970@126.com
Vildagliptin Attenuates Myocardial Dysfunction and Restores Autophagy via miR-21/SPRY1/ERK in Diabetic Mice Heart.
g.chiellini@bm.med.unipi.it
New Insights into the Potential Roles of 3-Iodothyronamine (T1AM) and Newly Developed Thyronamine-Like TAAR1 Agonists in
weiyanggaoi@126.com
Positive Effect of Andrographolide Induced Autophagy on Random-Pattern Skin Flaps Survival.
jihongwu@fudan.edu.cn
Paeonol Induces Protective Autophagy in Retinal Photoreceptor Cells.
cuixh@tongji.edu.cn
HLH-30/TFEB modulates autophagy to improve proteostasis in Aβ transgenic Caenorhabditis elegans.
lilong@nbu.edu.cn
Micronized Palmitoylethanolamide Ameliorates Methionine- and Choline-Deficient Diet-Induced Nonalcoholic Steatohepatitis
minzhouzhang@aliyun.com
Tongguan Capsule Mitigates Post-myocardial Infarction Remodeling by Promoting Autophagy and Inhibiting Apoptosis: Role o
eycaojie@scut.edu.cn
Enhanced tumor suppression in colorectal cancer via berberine-loaded PEG-PLGA nanoparticles.
xinguang@scu.edu.cn
Xanthohumol alleviates oxidative stress and impaired autophagy in experimental severe acute pancreatitis through inhibit
xuyaozhang@fudan.edu.cn
Enhancing antitumor efficacy of CLDN18.2-directed antibody-drug conjugates through autophagy inhibition in gastric cance
wanghao@nanoctr.cn
A self-destructive nanosweeper that captures and clears amyloid β-peptides
fanjiao@301hospital.com.cn
MLN4924 inhibits macrophage foam cell formation by enhancing autophagy and regulating metabolic phenotype.
meixifan@jzmu.edu.cn
Resveratrol inhibits LPS-induced apoptosis in VSC4.1 motoneurons through enhancing SIRT1-mediated autophagy.
huangjh@fmmu.edu.cn
Epothilone B Facilitates Peripheral Nerve Regeneration by Promoting Autophagy and Migration in Schwann Cells.
hemachandra.reddy@ttuhsc.edu
Amyloid Beta and Phosphorylated Tau-Induced Defective Autophagy and Mitophagy in Alzheimer’s Disease