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The role of combining immunotherapy with primary (Chemo)radiotherapy in curative treatment settings of the head and neck
Combination with Stereotactic Body Radiotherapy Offers a Promising Strategy to Overcome Resistance to Immunotherapy in A
Translating Knowledge About the Immune Microenvironment of Gastrointestinal Stromal Tumors into Effective Clinical Strat
Abscopal Effects and Immunomodulation in Skin Cancer Therapy.
Combining conventional therapy with immunotherapy: A risky business?
Personalized cancer vaccines and their integration with standard of care modalities.
Combining targeted therapy with immunotherapy. Can 1+1 equal more than 2?
Experimental Investigation of Hematological Toxicity After Radiation Therapy Combined With Immune Checkpoint Inhibitors.
Combining immunotherapies for the treatment of prostate cancer.
Time to abandon single-site irradiation for inducing abscopal effects.
Lung Cancer: Advances in Diagnosis and Management
Lighting up the fire in cold tumors to improve cancer immunotherapy by blocking the activity of the autophagy-related pr
Getting personal in metastatic melanoma: neoantigen-based vaccines as a new therapeutic strategy.
Targeted Therapies Combined With Immune Checkpoint Therapy.
Clinical outcomes and longitudinal circulating tumor DNA changes after treatment with nivolumab and olaparib in immunoth
Low-dose irradiation for reversing immunotherapy resistance: how to translate?
Radiotherapy for Melanoma: More than DNA Damage.
Current and Future Aspects of Immunotherapy for Esophageal and Gastric Malignancies.
Oligometastatic Melanoma Treated by Metastasectomy in Combination with Immune Checkpoint and BRAF Inhibitors: A Case Ser
Combination approaches in NSCLC involving immune checkpoint inhibitors.
Prospects for Treatment of Lung Cancer Using Activated Lymphocytes Combined with Other Anti-Cancer Modalities
Combining Radiation Therapy with Immune Checkpoint Blockade for Central Nervous System Malignancies.
Public Adverse Event Data Insights into the Safety of Pembrolizumab in Melanoma Patients.
Rationale for Combining Bispecific T Cell Activating Antibodies With Checkpoint Blockade for Cancer Therapy.
Modulation of CD8+ T Cell Responses by Radiotherapy-Current Evidence and Rationale for Combination with Immune Checkpoin
Retrospective Side Effect Profiling of the Metastatic Melanoma Combination Therapy Ipilimumab-Nivolumab Using Adverse Ev
The role of immunotherapy in small cell lung cancer.
Systemic treatments for metastatic cutaneous melanoma
HOOK1 Inhibits the Progression of Renal Cell Carcinoma via TGF‐<i>β</i> and TNFSF13B/VEGF‐A Axis
Poxvirus-based active immunotherapy synergizes with CTLA-4 blockade to increase survival in a murine tumor model by impr
Paracrine release of IL-2 and anti-CTLA-4 enhances the ability of artificial polymer antigen-presenting cells to expand
Role of radiotherapy in improving activity of immune-modulating drugs in advanced renal cancer: Biological rationale and
First-line immunotherapy in advanced non-small-cell lung cancer patients with ECOG performance status 2: results of an I
Primary and metastatic brain cancer genomics and emerging biomarkers for immunomodulatory cancer treatment
Advancing immunotherapy for early-stage triple-negative breast cancer
Lung cancer: current therapies and new targeted treatments
Regulatory T cells in cancer immunotherapy
Programmed cell death protein-1 inhibitor for the treatment of hepatocellular carcinoma: “A sharp sword”
NCCN Guidelines Insights: Non–Small Cell Lung Cancer, Version 2.2021
Gastric Cancer, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology
Neoantigen cancer vaccine augments anti-CTLA-4 efficacy.
A guide to cancer immunotherapy: from T cell basic science to clinical practice
Immunotherapy in colorectal cancer: rationale, challenges and potential
Head and neck squamous cell carcinoma
Advances in immunotherapy for hepatocellular carcinoma
Targeting EZH2 to overcome the resistance to immunotherapy in lung cancer
Tremelimumab plus Durvalumab in Unresectable Hepatocellular Carcinoma
First-Line Atezolizumab plus Chemotherapy in Extensive-Stage Small-Cell Lung Cancer
Overall Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma
Atezolizumab for First-Line Treatment of Metastatic Nonsquamous NSCLC
Macrophages impede CD8 T cells from reaching tumor cells and limit the efficacy of anti–PD-1 treatment
Combined Nivolumab and Ipilimumab in Melanoma Metastatic to the Brain
Nivolumab plus Ipilimumab versus Sunitinib in Advanced Renal-Cell Carcinoma
Dosing immunotherapy combinations: Analysis of 3,526 patients for toxicity and response patterns.
Novel immunotherapy combinations for genitourinary cancers.
Immunogenicity and antitumor efficacy of a novel human PD-1 B-cell vaccine (PD1-Vaxx) and combination immunotherapy with
Metastatic non-small cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
First report of overall survival for ipilimumab plus nivolumab from the phase III Checkmate 067 study in advanced melano
Side effect management during immune checkpoint blockade using CTLA-4 and PD-1 antibodies for metastatic melanoma - an u
Dahuang Fuzi Baijiang decoction restricts progenitor to terminally exhausted T cell differentiation in colorectal cancer
Regulation of programmed death‐ligand 1 expression in response to DNA damage in cancer cells: Implications for precision
Immune Checkpoint Inhibitors for the Treatment of Cancer: Clinical Impact and Mechanisms of Response and Resistance
Prophylactic IL-23 blockade uncouples efficacy and toxicity in dual CTLA-4 and PD-1 immunotherapy.
Genomic Profiling of Radiation-Induced Sarcomas Reveals the Immunologic Characteristics and Its Response to Immune Check
Combination Therapies to Improve the Efficacy of Immunotherapy in Triple-negative Breast Cancer
PD-1 Checkpoint Inhibitor Associated Autoimmune Encephalitis
Immune Checkpoint Inhibitors in the Treatment of Patients with Neuroendocrine Neoplasia
Novel immune checkpoint targets: moving beyond PD-1 and CTLA-4.
Combination of CTLA-4 and PD-1 blockers for treatment of cancer.
Combinatorial approach to cancer immunotherapy: strength in numbers.
Plinabulin, a novel small molecule clinical stage IO agent with anti-cancer activity, to prevent chemo-induced neutropen
Impact of prophylactic TNF blockade in the dual PD-1 and CTLA-4 immunotherapy efficacy and toxicity.
Phase II study of ipilimumab, nivolumab, and panitumumab in patients with <i>KRAS</i>/<i>NRAS</i>/<i>BRAF</i> wild-type
Complete Local and Abscopal Responses from a Combination of Radiation and Nivolumab in Refractory Hodgkin's Lymphom
Non-small cell lung cancer: current treatment and future advances
Use of Programmed Death Receptor-1 and/or Programmed Death Ligand 1 Inhibitors for the Treatment of Brain Metastasis of
Melanoma: Prognostic Factors and Factors Predictive of Response to Therapy
MATTERHORN: phase III study of durvalumab plus FLOT chemotherapy in resectable gastric/gastroesophageal junction cancer
Analysis of combination therapy of immune checkpoint inhibitors in osteosarcoma.
Immunotherapy in Malignant Pleural Mesothelioma.
Liver immunotolerance and hepatocellular carcinoma: Patho-physiological mechanisms and therapeutic perspectives.
Oncolytic viruses as engineering platforms for combination immunotherapy.
Fulminant Type 1 Diabetes Mellitus Accompanied by Positive Conversion of Anti-insulin Antibody after the Administration
Intratumoral delivery of PD-1/PD-L1 and CTLA-4 inhibitors for recurrent/refractory solid tumors: a proof-of-concept trea
Update on Programmed Death-1 and Programmed Death-Ligand 1 Inhibition in the Treatment of Advanced or Metastatic Non-Sma
Abstract 2951: NI-2901, an affinity-optimized CD47xPD-L1 bispecific antibody for dual immune checkpoint blockade
Desensitizing Effect of Intra-Tumoral GDF-15 on Immunotherapy in Patients With Advanced Non-Small Cell Lung Cancer.
Efficacy of PD-1/PD-L1 inhibitors in patients with non-small cell lung cancer and brain metastases: A real-world retrosp
Molecular characterization of clinical responses to PD-1/PD-L1 inhibitors in non-small cell lung cancer: Predictive valu
Diabetic ketoacidosis shortly after COVID-19 vaccination in a non-small-cell lung cancer patient receiving combination o
C-PLAN index as a prognostic factor for patients with previously untreated advanced non-small cell lung cancer who recei
The adverse events associated with combination immunotherapy in cancers: Challenges and chances.
TIM‐3 expression induces resistance to PD‐1 inhibitor in G‐CSF‐producing lung spindle cell carcinoma: A case report
Immune checkpoint inhibitors in advanced upper and lower tract urothelial carcinoma: a comparison of outcomes
Real‐world efficacy and toxicity of combined nivolumab and ipilimumab in patients with metastatic melanoma
Combination immunotherapy with interleukin‐2 surface‐modified tumor cell vaccine and programmed death receptor‐1 blockad
Nano-Immunoconjugates in Immune Checkpoint Blockade: A Dual Approach to Precision Immunotherapy and Real-Time Imaging.
A phase II trial of nivolumab followed by ipilimumab and nivolumab in advanced non‐clear‐cell renal cell carcinoma
Opportunities for using in silico-based extended dosing regimens for monoclonal antibody immune checkpoint inhibitors.
Investigation of poor predictive factors in extensive stage small cell lung cancer under etoposide‐platinum‐atezolizumab
Expression profiling of single cells and patient cohorts identifies multiple immunosuppressive pathways and an altered N
Erythema nodosum-like panniculitis mimicking disease recurrence: A novel toxicity from immune checkpoint blockade therap
Antipodoplanin antibody enhances the antitumor effects of CTLA-4 blockade against malignant mesothelioma by natural kill
CD20<sup>+</sup> tumor‐infiltrating immune cells and CD204<sup>+</sup> M2 macrophages are associated with prognosis in t
Immunotherapy and Novel Combinations in Oncology: Current Landscape, Challenges, and Opportunities
PD-L1 and IDO expression in cervical and vulvar invasive and intraepithelial squamous neoplasias: implications for combi
Complete response to pembrolizumab after initial progress in a patient with metastatic uveal melanoma
Dermatologic toxicity from immune checkpoint blockade therapy with an interstitial granulomatous pattern
The Immunosuppressive Microenvironment of Glioblastoma: Mechanisms, Clinical Challenges and Future Directions.
A new strategy for immunotherapy of microsatellite-stable (MSS)-type advanced colorectal cancer: Multi-pathway combinati
Toxicity and response to ipilimumab and nivolumab in older patients with metastatic melanoma: A multicentre retrospectiv
Particle Radiation Therapy With Immunotherapy for Advanced Hepatocellular Carcinoma: Emerging Evidence and Remaining Que
Targeting regulatory T cells in anti-PD-1/PD-L1 cancer immunotherapy.
A bi-adjuvant nanovaccine that potentiates immunogenicity of neoantigen for combination immunotherapy of colorectal canc
Tumor immunological phenotype signature-based high-throughput screening for the discovery of combination immunotherapy c
Microbiota-dependent activation of CD4+ T cells induces CTLA-4 blockade-associated colitis via Fcγ receptors.
A major responder to ipilimumab and nivolumab in metastatic uveal melanoma with concomitant autoimmunity
Engineering nanoparticles to locally activate T cells in the tumor microenvironment
Developing combination immunotherapies against cancer that make sense
A Combination of Anti-PD-L1 Treatment and Therapeutic Vaccination Facilitates Improved Retroviral Clearance via Reactiva
High antigen burden drives CD8+ T cell dysfunction in a mouse model of chronic hepatitis B virus infection
Parameters of Tumor Microenvironment Determine Effectiveness of Anti-PD-1/PD-L1 Therapy.
Susceptible loci associated with autoimmune disease as potential biomarkers for checkpoint inhibitor-induced immune-rela
Thyroid storm induced by combined nivolumab and ipilimumab immunotherapy in advanced non-small cell lung cancer
Severe thromboembolic phenomenon in the setting of pseudoprogression of melanoma brain metastases in response to combina
Treatment of atypical pulmonary carcinoid with combination ipilimumab and nivolumab.
Safety, immunogenicity, and clinical efficacy of durvalumab in combination with folate receptor alpha vaccine TPIV200 in
European Medicines Agency extension of indication to include the combination immunotherapy cancer drug treatment with ni
Phenotypic CD8 T cell profiling in chronic hepatitis B to predict HBV-specific CD8 T cell susceptibility to functional r
HHLA2 and PD-L1 co-expression predicts poor prognosis in patients with clear cell renal cell carcinoma
Targeting prognostic proinflammatory biomarkers to improve outcome on IO drugs
Granzyme B PET imaging of immune-mediated tumor killing as a tool for understanding immunotherapy response
Analysis of tumor-infiltrating NK and T cells highlights IL-15 stimulation and TIGIT blockade as a combination immunothe
458 Antitumor mechanisms of local radiation and combination immunotherapy in an immunologically cold model of neuroblast
Differential combination immunotherapy requirements for inflamed (warm) tumors versus T cell excluded (cool) tumors: eng
Combination checkpoint blockade for metastatic cutaneous malignancies in kidney transplant recipients.
Co-inhibitor expression on tumor infiltrating and splenic lymphocytes after dual checkpoint inhibition in a microsatelli
A highly stable multifunctional aptamer for enhancing antitumor immunity against hepatocellular carcinoma by blocking du
Development of cancer immunotherapy based on PD-1/PD-L1 pathway blockade.
A New Combination Immunotherapy in Advanced Melanoma.
Immuno-pharmacodynamics for evaluating mechanism of action and developing immunotherapy combinations.
[The role of immunooncology in the treatment of urothelial cancer].
Current status of immunotherapy in gastrointestinal malignancies.
Combination Immunotherapy for Hepatocellular Carcinoma: Where Are We Currently?
[Immunotherapy for renal cell carcinoma - current status].
Fulminant Myocarditis with Combination Immune Checkpoint Blockade
Immunotherapy in Advanced Non-Small Cell Lung Cancer
Cryoablation combined with dual immune checkpoint blockade enhances antitumor efficacy in hepatocellular carcinoma model
Future directions in Hodgkin lymphoma: checkpoint inhibitors and beyond.
The Prognostic Value of Albumin-Globulin Ratio and Eosinophil-Neutrophil Ratio in Patients with Advanced Tumors Undergoi
CTLA4 antagonists in phase I and phase II clinical trials, current status and future perspectives for cancer therapy.
Combination immunotherapy of oncolytic virus nanovesicles and PD-1 blockade effectively enhances therapeutic effects and
Neoadjuvant therapy for triple-negative breast cancer: potential predictive biomarkers of activity and efficacy of plati
Interleukin-33 in the Regulation of Autophagy and Apoptosis in Macrophages During Infection.
Single vs. combination immunotherapeutic strategies for glioma
Nanoparticle albumin bound-paclitaxel for treatment of advanced non-small cell lung cancer: an evaluation of the clinica
Nivolumab + relatlimab for the treatment of unresectable or metastatic melanoma.
Building on the anti-PD1/PD-L1 backbone: combination immunotherapy for cancer
Is there still a role for talimogene laherparepvec (T-VEC) in advanced melanoma? An indirect efficacy comparison of T-VE
Prostate cancer immunotherapy.
Basis for molecular diagnostics and immunotherapy for esophageal cancer.
Combining anti-cytotoxic T-lymphocyte antigen 4 (CTLA-4) and -programmed cell death protein 1 (PD-1) agents for cancer i
Pembrolizumab and other immune checkpoint inhibitors in locally advanced or metastatic Merkel Cell Carcinoma: safety and
Next-generation immunotherapy for solid tumors: combination immunotherapy with crosstalk blockade of TGFβ and PD-1/PD-L1
Immune checkpoint inhibitor resumption after discontinuation due to immune-related adverse events: a nomogram-based anal
New strategies to enhance the efficacy of PD-1/PD-L1 inhibitors in treating microsatellite stable colorectal cancer.
Overcoming toxicity challenges in immune checkpoint inhibitor treatment of high-risk metastatic cancers.
Checkpoint inhibitors in head and neck cancer
Nivolumab Plus Relatlimab: First Approval.
The Role of Anti-PD-1/PD-L1 in the Treatment of Skin Cancer
Melanoma Brain Metastases: An Update on the Use of Immune Checkpoint Inhibitors and Molecularly Targeted Agents.
Complete response to pembrolizumab in mismatch repair-deficient urothelial carcinoma with local recurrence and recurrent
Expression of costimulatory and inhibitory receptors in FoxP3+ regulatory T cells within the tumor microenvironment: Imp
Tumor-Activated Carrier-Free Prodrug Nanoparticles for Targeted Cancer Immunotherapy: Preclinical Evidence for Safe and
From immune checkpoints to vaccines: The past, present and future of cancer immunotherapy.
Combinatorial Cancer Immunotherapies.
Guiding immunotherapy combinations: Who gets what?
SY4-1 Combination immunotherapy using anti-PD-1/PD-L1 plus anti-CTLA-4 antibodies
Expert opinion on immunotherapy induced diabetes.
PD-L1 expression by immunohistochemistry in salivary duct carcinoma.
Overcoming Immunotherapy Resistance With Radiation Therapy and Dual Immune Checkpoint Blockade.
325P A phase II, open-label, single-center study of QL1706 plus platinum doublet chemotherapy with or without bevacizuma
Immunotherapy use outside clinical trial populations: never say never?
213P Prognostic significance of absolute lymphocyte count in patients with metastatic renal cell carcinoma treated with
Real-world evaluation of the effectiveness and predictive factors of anti-PD-1/PD-L1 inhibitors as the first-line therap
Salvage Surgery for Thoracic SMARCA4-Deficient Undifferentiated Tumor.
Breaking the mold: Overcoming resistance to immune checkpoint inhibitors.
Strategies for developing PD-1 inhibitors and future directions.
A novel bispecific nanobody with PD-L1/TIGIT dual immune checkpoint blockade.
PD-L1 antibody-modified plant-derived nanovesicles carrying a STING agonist for the combinational immunotherapy of melan
Mechanistic considerations in chemotherapeutic activity of caffeine.
[PD-L1 expression and PD-1/PD-L1 inhibitors in breast cancer].
Comparative druggability of PD-1/PD-L1 inhibitors (A56, HD10): Cross-species differences in PD-L1 exposure and efficacy.
Immunotherapy for extensive-stage small cell lung cancer: current status, challenges and future strategies.
CD8+ T cell exhaustion and cancer immunotherapy.
PAK4 inhibition improves PD1 blockade immunotherapy in prostate cancer by increasing immune infiltration.
Evaluation of TMB as a predictive biomarker in patients with solid cancers treated with anti-PD-1/CTLA-4 combination imm
Imaging immune checkpoint networks in cancer tissues with supermultiplexed SERS nanoprobes.
The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer
Clinical drug screening reveals clofazimine potentiates the efficacy while reducing the toxicity of anti-PD-1 and CTLA-4
Genomic Features of Response to Combination Immunotherapy in Patients with Advanced Non-Small-Cell Lung Cancer.
Combination Immunotherapy with CAR T Cells and Checkpoint Blockade for the Treatment of Solid Tumors.
Genomic Features of Response to Combination Immunotherapy in Lung Cancer.
Tumor-associated high endothelial venules mediate lymphocyte entry into tumors and predict response to PD-1 plus CTLA-4
PD-1-mediated inhibition of T cell activation: Mechanisms and strategies for cancer combination immunotherapy.
Assessing clonal changes in T cells over time following immunotherapy is a breeze with Cyclone.
Phenotypic characterization of tumor CTLA-4 expression in melanoma tissues and its possible role in clinical response to
Cutaneous immune-related adverse events to checkpoint inhibitors.
Combination Strategies on the Basis of Immune Checkpoint Inhibitors in Non-Small-Cell Lung Cancer: Where Do We Stand?
A combination of PD-1 and TIGIT immune checkpoint inhibitors elicits a strong anti-tumour response in mesothelioma.
Acute rhabdomyolysis with severe polymyositis following ipilimumab-nivolumab treatment in a cancer patient with elevated
How do I steer this thing? Using dendritic cell targeted vaccination to more effectively guide the antitumor immune resp
Metastatic Merkel cell carcinoma response to nivolumab.
Combination immunotherapy: a road map.
A New VISTA on combination therapy for negative checkpoint regulator blockade.
Targeting adenosine for cancer immunotherapy
Fatal enteric plexus neuropathy after one dose of ipilimumab plus nivolumab: a case report
Combination immunotherapy and radiotherapy causes an abscopal treatment response in a mouse model of castration resistan
A robust response to combination immune checkpoint inhibitor therapy in HPV-related small cell cancer: a case report
The age of enlightenment in melanoma immunotherapy
Quick efficacy seeking trial (QuEST1): a novel combination immunotherapy study designed for rapid clinical signal assess
Cryotherapy for nodal metastasis in NSCLC with acquired resistance to immunotherapy.
Characterization of immune responses to anti-PD-1 mono and combination immunotherapy in hematopoietic humanized mice imp
Immune induction strategies to enhance responses to PD-1 blockade: lessons from the TONIC trial
Anti-pancreatic tumor efficacy of a Listeria-based, Annexin A2-targeting immunotherapy in combination with anti-PD-1 ant
PD-L1 blockade engages tumor-infiltrating lymphocytes to co-express targetable activating and inhibitory receptors.
Response to combined ipilimumab and nivolumab after development of a nephrotic syndrome related to PD-1 monotherapy
Targeting interferon signaling and CTLA-4 enhance the therapeutic efficacy of anti-PD-1 immunotherapy in preclinical mod
Exploring the Role of Combination Immunotherapy in Metastatic Renal Cell Carcinoma
Immunotherapy in Older Adults With Advanced Cancers: Implications for Clinical Decision-Making and Future Research
Combination Immunotherapy Development in Melanoma.
Nonsurgical Management of Melanoma Brain Metastasis: Current Therapeutics, Challenges, and Strategies for Progress
Combination immunotherapy with IDO vaccine and PD-1 inhibitors in advanced NSCLC.
Pneumonitis in Patients Treated With Anti–Programmed Death-1/Programmed Death Ligand 1 Therapy
Neoadjuvant combination immunotherapy with ipilimumab (3 mg/kg or 10mg/kg) and high dose IFN-a2b in locally/regionally a
Neutrophil lymphocyte ratio (NLR) as a predictive biomarker for PD-1/PD-L1 directed therapy in metastatic non-small cell
NSABP FC-9: Phase II study of dual immune checkpoint blockade (ICB) with durvalumab (D) plus tremelimumab (T) following
LCCC 1525: Combination immunotherapy with cyclophosphamide plus pembrolizumab in patients with advanced triple negative
Comprehensive molecular profiling of metastatic melanoma to predict response to monotherapy and combination immunotherap
Current Therapy for Metastatic Head and Neck Cancer: Evidence, Opportunities, and Challenges
Effect of combination immunotherapy on tumor growth, survival, and intratumoral immune infiltration in transgenic murine
Cost-effectiveness of single versus dual immune checkpoint blockade for chemotherapy-refractory esophageal, GE junction,
Prognostic implications of tumor associated macrophages (TAMs) in soft tissue sarcoma.
A phase II clinical trial of ipilimumab/nivolumab combination immunotherapy in patients with rare upper gastrointestinal
Bone metastases treated with immune checkpoint inhibitors: A single center experience.
A phase II study of dual immune checkpoint blockade (ICB) plus androgen receptor (AR) blockade to enhance thymic T-cell
Tumor mutational burden (TMB) and response rates to immune checkpoint inhibitors (ICIs) targeting PD-1, CTLA-4, and comb
Combination immunotherapy with ipilimumab and nivolumab in patients with advanced biliary tract cancers.
Association between immune-related adverse events (irAEs) and clinical outcomes (CO) in advanced urothelial cancer patie
Correlation between circulating cell-free RNA biomarkers and response during combination immunotherapy in previously ref
Combination immunotherapy with ipilimumab and nivolumab in patients with rare gynaecological malignancies.
Expression patterns of PD-L1 and other immune checkpoint molecules in gastric cancer.
Interim results from the OPTIMAL trial: A phase II clinical trial of combination nivolumab, ipilimumab, and taxane in pa
The change of serum C-reactive protein levels during molecular-targeted treatments could predict the response to anti-PD
Immunotherapies for advanced hepatocellular carcinoma.
The New Immuno-Oncology-Based Therapies and Their Perspectives in Hepatocellular Carcinoma.
The Relationship Between Response Rate and Survival Benefits in Randomized Immunotherapy Studies.
Efficacy of immune checkpoint inhibitors along with chemotherapy in non-small cell lung cancer and the impact on adverse
Current and emerging options for patients with melanoma brain metastases.
[Immune combination possibilities in the first-line treatment of metastatic renal cell cancer].
Can Immune-related adverse events serve as clinical biomarkers of PD-1/PD-L1 inhibitor efficacy in Pan-Cancer Patients?
Immunotherapy for the treatment of breast cancer: checkpoint blockade, cancer vaccines, and future directions in combina
[Immuno-oncology--silver bullets or mass destruction weapons?].
Robotic-assisted cytoreductive partial nephrectomy for metastatic sarcomatoid renal cell carcinoma following dramatic re
Anti-PD1 antibody enhances the anti-tumor efficacy of MUC1-MBP fusion protein vaccine via increasing Th1, Tc1 activity a
PD-1 and TIGIT coexpressing CD8 + CD103 + tissue-resident memory cells in endometrial cancer as potential targets for im
Combined immunotherapy for metastatic triple-negative breast cancer based on PD-1/PD-L1 immune checkpoint blocking.
Exosomal PD-L1 in non-small cell lung Cancer: Implications for immune evasion and resistance to immunotherapy.
The current advances and future directions of PD-1/PD-L1 blockade in head and neck squamous cell carcinoma (HNSCC) in th
Combined prostate cancer vaccine plus immune checkpoint inhibition synergizes to eliminate prostate cancer.
Ansofaxine suppressed NSCLC progression by increasing sensitization to combination immunotherapy.
Myocarditis, Myositis, and Myasthenia Gravis: The Complexities of Treating Steroid-Refractory Triple M Syndrome.
Rational combination immunotherapeutic approaches for effective cancer treatment.
Autoimmune Cardiotoxicity of Cancer Immunotherapy.
Association of age with survival in older patients with cutaneous melanoma treated with immune checkpoint inhibitors.
Revealing anti-PD-1 resistance mechanisms in HCC: A path towards novel combination immunotherapies
FGF19/FGFR4-mediated elevation of ETV4 facilitates hepatocellular carcinoma metastasis by upregulating PD-L1 and CCL2.
Immune checkpoint inhibitors retain effectiveness in older patients with cutaneous metastatic melanoma.
Challenges of combination therapy with immune checkpoint inhibitors for hepatocellular carcinoma.
Combination immunotherapy for hepatocellular carcinoma.
Combination immunotherapy of glioblastoma with dendritic cell cancer vaccines, anti-PD-1 and poly I:C.
Targeted Therapy of Melanoma.
ES02.04 Concurrent, Sequential and Combination Immunotherapy Regimens in LA-NSCLC
Increased Response Rates to Salvage Chemotherapy Administered after PD-1/PD-L1 Inhibitors in Patients with Non-Small Cel
Autoimmune polyradiculitis due to combination immunotherapy with ipilimumab and nivolumab for the treatment of metastati
EP1.01-55 Neoantigen Deletion Leads to Hyperprogressive Disease (HPD) in Non-Small Cell Lung Cancer (NSCLC) Treated with
P2.11A.13 Cytokine Release Syndrome from Dual Immune Checkpoint Blockade in Non-Small Cell Lung Cancer: FAERS Analysis
Increased Response Rates to Salvage Chemotherapy Administered after PD-1/PD-L1 Inhibitors in Patients with Non-Small Cel
Discordant Response to Nivolumab Plus Ipilimumab and Identification of BRAF V600E Mutation in Biphasic Malignant Pleural
- **DOI:** 10.1016/j.jval.2019.09.554 - **Authors:** A. Bamrara, N. Mishra, S. Takyar - **Year:** 2019 - **Journal:** Va
PCN202 How Should VALUE be Attributed to the Constituent Parts of Combination Immunotherapy in NON-SMALL Cell LUNG Cance
Brief Report: Real-World Toxicity and Survival of Combination Immunotherapy in Pleural Mesothelioma-RIOMeso.
Immune checkpoint inhibitors in epidermal growth factor receptor mutant non-small cell lung cancer: Current controversie
Nivolumab plus ipilimumab: A promising first-line therapy for hepatocellular carcinoma.
Clinical value of neutrophil-to-lymphocyte ratio in patients with non-small-cell lung cancer treated with PD-1/PD-L1 inh
66 Early Experiences of the Use of Combination Immunotherapy for the Treatment of Malignant Mesothelioma from 2022–2023
Impact of senescence cell signature in patients with non-small cell carcinoma and melanoma receiving PD-L1/PD-1 inhibito
Tumor microenvironment and immune-related therapies of head and neck squamous cell carcinoma.
An oral cancer vaccine using a Bifidobacterium vector suppresses tumor growth in a syngeneic mouse bladder cancer model.
Neospora caninum as delivery vehicle for anti-PD-L1 scFv-Fc: A novel approach for cancer immunotherapy.
Akt inhibition enhances the antitumor efficacy of immune checkpoint blockades and radiotherapy in a syngeneic breast can
Interpretable systems biomarkers predict response to immune-checkpoint inhibitors.
PD-L1 expression predicts longer disease free survival in high risk head and neck cutaneous squamous cell carcinoma.
Complete response with neoadjuvant avelumab in Merkel cell carcinoma - A case report.
Dual CTLA-4 and PD-L1 Blockade Inhibits Tumor Growth and Liver Metastasis in a Highly Aggressive Orthotopic Mouse Model
Lymphocyte-activation gene 3 (LAG-3) as a promising immune checkpoint in cancer immunotherapy: From biology to the clini
Prospective role of PD-1/PD-L1 immune checkpoint inhibitors in GI cancer.
Tumor microenvironment changes leading to resistance of immune checkpoint inhibitors in metastatic melanoma and strategi
Predictors of Radiation Resistance and Novel Radiation Sensitizers in Head and Neck Cancers: Advancing Radiotherapy Effi
Adverse events of targeted anticancer therapies: what radiologists need to know.
[Sarcoid-like granulomatosis in cancer patients treated with immune checkpoints inhibitors].
Atypical metastatic lung cancer of the right ventricle on FDG PET/CT.
Combination immunotherapy of nivolumab plus ipilimumab in a lung cancer patient with Werner syndrome; a case report.
A multicenter randomized phase II study of nivolumab in combination with gemcitabine/cisplatin or ipilimumab as first-li
A phase III study (COSMIC-313) of cabozantinib (C) in combination with nivolumab (N) and ipilimumab (I) in patients (pts
Patient and treatment characteristics of emergency presentations due to immune-mediated toxicities.
Association of baseline neutrophil-to-eosinophil ratio (NER) and neutrophil-to-lymphocyte ratio (NLR) with response to c
Quantification of immune response after dual checkpoint inhibition in a microsatellite stable model of colorectal cancer
A phase II trial of durvalumab (MEDI4736) and tremelimumab with chemotherapy in metastatic EGFR mutant non-squamous non-
Deciphering primary and acquired immunotherapy resistance with whole genome and transcriptome analysis (WGTA).
Timing of immunotherapy-induced pneumonitis in patients with primary lung malignancy.
Dual immune checkpoint blockade in advanced well-differentiated neuroendocrine tumors, a phase II clinical trial.
Hospital admissions and subsequent outcomes from immune-related adverse events.
Systemic impact on tumor growth after combined immuno-thermal ablation in a murine model of colorectal cancer.
Efficacy and safety of QL1706, a novel dual immune checkpoint blockade containing a mixture of anti-PD1 IgG4 and anti-CT
An open-label, multicenter, adaptive, phase Ib/II study of QL1706 or QL1604 plus bevacizumab as first-line treatment in
Phase II evaluation of combination immunotherapy with CV301, N-803, bintrafusp alfa, and M9241 in patients with advanced
Phase 3 randomized, open-label, multicenter study of tremelimumab (T) and durvalumab (D) as first-line therapy in patien
Efficacy and safety of QL1706, a novel dual immune checkpoint blockade containing a mixture of anti-PD1 IgG4 and anti-CT
Development of a kidney cancer ex vivo tumor model and image-based artificial intelligence tool for precision immunother
Personalized precision combination therapies based on potential actionability and coalterations and therapeutic opportun
Patterns of immune-related adverse events (irAEs) in adolescent and young adult (AYA) patients with melanoma receiving i
The survival benefits and the risk of severe renal injury of immune checkpoint inhibitors in patients with cancer: The r
Overall survival after isolated hepatic perfusion in combination with ipilimumab and nivolumab in patients with uveal me
The pan-cancer landscape of SMARCA4 and SMARCB1 alterations in a large cohort of Chinese patients.
Combined treatment of durvalumab, bevacizumab and tremelimumab in subjects with hepatocellular carcinoma (HCC) or biliar
A phase 1/2 study of favezelimab in combination with pembrolizumab for anti–PD-1–naive relapsed or refractory (R/R) clas
Use of early circulating tumour DNA dynamics in patients with stage III melanoma receiving neoadjuvant combination immun
Topological heterogeneity of genomic and immunologic effects from combination immunotherapy treatment in the neoadjuvant
A randomized phase I/II study of neoadjuvant treatment with 177-Lutetium-PSMA-617 with or without ipilimumab in patients
Phase I dose escalation trial of STX-001, an LNP-encapsulated self-replicating mRNA expressing IL-12, in patients (pts)
Gotistobart in combination with pembrolizumab in patients with advanced melanoma who have progressed on PD-1 inhibitors
Advanced renal cell cancer combination immunotherapy clinical trial (ARCITECT; HCRN GU 22-587).
Neoadjuvant immunotherapy for patients with resectable stage III/IV cutaneous melanoma: A Swedish retrospective real-wor
Longitudinal plasma proteomic analysis: A monitoring strategy for NSCLC patients treated with immunotherapy.
NSABP FC-13 (EMPIRE): A phase II platform study of cemiplimab monotherapy or cemiplimab-based combinations in patients w
Impact of Bone Metastasis in Stage IV Non–Small Cell Lung Cancer Treated With Durvalumab and Tremelimumab With or Withou
SAT-239 Combination of Immune Check Point Inhibitors Causing Hypopituitarism
Management of Advanced Pleural Mesothelioma-At the Crossroads.
SUN-127 Diagnostic Challenges Associated with the Rising Incidence of Endocrine Toxicity in the Era of Combination Immun
Tumor-Naïve Circulating Tumor DNA as an Early Response Biomarker for Patients Treated With Immunotherapy in Early Phase
Spectrum of Clinical Presentations, Imaging Findings, and HLA Types in Immune Checkpoint Inhibitor-Induced Hypophysitis.
Tumor Immune Profiling-Based Neoadjuvant Immunotherapy for Locally Advanced Melanoma.
Research Progress of PD-1/PD-L1 Inhibitors in the Treatment of Advanced Gastric Carcinoma
Imaging evaluation of lung cancer treated with PD-1/PD-L1 inhibitors.
Encouraging specific biomarkers-based therapeutic strategies for hepatocellular carcinoma.
Preclinical Development of Ipilimumab and Nivolumab Combination Immunotherapy: Mouse Tumor Models, In Vitro Functional S
Abscopal effects observed in cancer radiation therapy and oncolytic virotherapy: an overview.
Optimal timing of steroid initiation in response to CTLA-4 antibody in metastatic cancer: A mathematical model.
Combination therapy for mCRPC with immune checkpoint inhibitors, ADT and vaccine: A mathematical model.
[Combined Regimens in Immunotherapy].
Elevated Liver Enzymes in a Patient With Hepatocellular Carcinoma on Immune Checkpoint Inhibitor Therapy: A Diagnostic a
PD-1/PD-L1 expression in pancreatic cancer and its implication in novel therapies
42 Intravital multiphoton microscopy of infiltrating T cell and tumor cell metabolism in a murine melanoma model
342 A phase 3 study (COSMIC-313) of cabozantinib in combination with nivolumab and ipilimumab in patients with previousl
Antitumor efficacy of combined CTLA4/PD-1 blockade without intestinal inflammation is achieved by elimination of FcγR in
457 KEYNOTE-495/KeyImPaCT: interim analysis of a randomized, biomarker-directed, phase 2 trial of pembrolizumab-based co
Combination anti-PD1 and ipilimumab therapy in patients with advanced melanoma and pre-existing autoimmune disorders.
Combination immunotherapy with nivolumab and ipilimumab in patients with rare gynecological malignancies: results of the
Characterization of the treatment-naive immune microenvironment in melanoma with <i>BRAF</i> mutation
Biomarker analysis from CheckMate 214: nivolumab plus ipilimumab versus sunitinib in renal cell carcinoma
Phase I trial of KN046, a novel bispecific antibody targeting PD-L1 and CTLA-4 in patients with advanced solid tumors
913 A murine gastric cancer YTN16 model for the rational design of combination immunotherapy
Multiomic molecular characterization of the response to combination immunotherapy in MSS/pMMR metastatic colorectal canc
Corticosteroid premedication on anti-tumor effect of immune checkpoint blockade in murine hepatocellular carcinoma model
Pancreatic cancer is feeling the heat
Unlocking the promise of innate biology through the HLA-G/ILT2/ILT4 pathway
Phase I study on neoadjuvant combination immunotherapy with mogamulizumab and nivolumab for solid tumors
553 Depletion of effector regulatory T cells drives major response to induction dual immune checkpoint blockade (ICB) in
[Strategies and perspectives for addressing immune checkpoint inhibitor resistance in the era of combination immunothera
1156 Small circular RNA vaccines for combination cancer immunotherapy
373 Dual immune checkpoint blockade enhances tumor-infiltrating lymphocyte expansion and survival in murine glioma model
Uncommon BRAF Mutations Associated with Durable Response to Immunotherapy in Patients with Metastatic Melanoma.
[Personalized modulation of tumor microimmune microenvironment for the development of effective combination immunotherap
Combination Immunotherapy Approaches for Pancreatic Cancer Treatment.
Prevalence of Epstein-Barr Virus Infection and Mismatch Repair Protein Deficiency and the Correlation of Immune Markers
LAG3 and PD1 Regulate CD8+ T Cell in Diffuse Large B-cell Lymphoma Patients
DNA Repair Deficiency in Breast Cancer: Opportunities for Immunotherapy.
Nivolumab and Ipilimumab Combination Immunotherapy for Patients with Metastatic Collecting Duct Carcinoma.
Pretreatment Neutrophil-to-Lymphocyte Ratio and Lactate Dehydrogenase Predict the Prognosis of Metastatic Cervical Cance
NXPH4 Used as a New Prognostic and Immunotherapeutic Marker for Muscle-Invasive Bladder Cancer.
Development of a Clinically Oriented Model to Predict Antitumor Effects after PD-1/PD-L1 Inhibitor Therapy
Hepatocellular Carcinoma: Current Therapeutic Algorithm for Localized and Advanced Disease
A Case of Immunotherapy-Induced Colitis Complicated by Perforation and Treated with Infliximab Postoperatively.
Associations of Clinical and Molecular Characteristics with the Response to Immune Checkpoint Blockade in Advanced Gastr
Durable Marked Response of Unresectable Esophageal Squamous Cell Carcinoma After Radiotherapy Alone Followed by Combinat
Data from Attenuation of Sialylation Augments Antitumor Immunity and Improves Response to Immunotherapy in Ovarian Cance
Landscape of Combination Immunotherapy and Targeted Therapy to Improve Cancer Management
Data from Attenuation of Sialylation Augments Antitumor Immunity and Improves Response to Immunotherapy in Ovarian Cance
Assessing Immune-Related Adverse Events of Efficacious Combination Immunotherapies in Preclinical Models of Cancer
Data from Attenuation of sialylation augments antitumor immunity and improves response to immunotherapy in ovarian cance
Attenuation of Sialylation Augments Antitumor Immunity and Improves Response to Immunotherapy in Ovarian Cancer.
Myeloid Cells Induce Infiltration and Activation of B Cells and CD4+ T Follicular Helper Cells to Sensitize Brain Metast
Data from Attenuation of Sialylation Augments Antitumor Immunity and Improves Response to Immunotherapy in Ovarian Cance
Data from Resistance to Radiotherapy and PD-L1 Blockade Is Mediated by TIM-3 Upregulation and Regulatory T-Cell Infiltra
Data from Bladder Preservation with Durvalumab plus Tremelimumab and Concurrent Radiotherapy in Patients with Localized
Data from Resistance to Radiotherapy and PD-L1 Blockade Is Mediated by TIM-3 Upregulation and Regulatory T-Cell Infiltra
Pan-Cancer Immunogenomic Perspective on the Tumor Microenvironment Based on PD-L1 and CD8 T-Cell Infiltration.
Characterization of a Pyroptosis-Related Signature for Prognosis Prediction and Immune Microenvironment Infiltration in
Mobilization of CD8+ T Cells via CXCR4 Blockade Facilitates PD-1 Checkpoint Therapy in Human Pancreatic Cancer.
Beyond Concurrent Chemoradiation: The Emerging Role of PD-1/PD-L1 Inhibitors in Stage III Lung Cancer.
Resistance to Radiotherapy and PD-L1 Blockade Is Mediated by TIM-3 Upregulation and Regulatory T-Cell Infiltration
Immunotherapy of Ipilimumab and Nivolumab in Patients with Advanced Neuroendocrine Tumors: A Subgroup Analysis of the CA
From Famine to Feast: Developing Early-Phase Combination Immunotherapy Trials Wisely
Timing of PD-1 Blockade Is Critical to Effective Combination Immunotherapy with Anti-OX40.
Synthetic High-density Lipoprotein Nanodiscs for Personalized Immunotherapy Against Gliomas
Single-cell Profiles and Prognostic Impact of Tumor-Infiltrating Lymphocytes Coexpressing CD39, CD103, and PD-1 in Ovari
Facts and Hopes in Immunotherapy of Soft-Tissue Sarcomas.
Association of Immune-Related Adverse Events, Hospitalization, and Therapy Resumption With Survival Among Patients With
Clinical Outcomes in Patients With Metastatic Lung Cancer Treated With PD-1/PD-L1 Inhibitors and Thoracic Radiotherapy.
Treatment Patterns and Attrition With Lines of Therapy for Advanced Urothelial Carcinoma in the US.
Emerging Role of Combination Immunotherapy in the First-line Treatment of Advanced Renal Cell Carcinoma
Single or combined immune checkpoint inhibitors compared to first-line platinum-based chemotherapy with or without bevac
Enhancing Triple Negative Breast Cancer Immunotherapy by ICG‐Templated Self‐Assembly of Paclitaxel Nanoparticles
Efficacy of Ipilimumab vs FOLFOX in Combination With Nivolumab and Trastuzumab in Patients With Previously Untreated ERB
Tumor Lysate‐Loaded Lipid Hybrid Nanovaccine Collaborated with an Immune Checkpoint Antagonist for Combination Immunothe
Durvalumab With or Without Tremelimumab for Patients With Metastatic Pancreatic Ductal Adenocarcinoma
Cocktail Strategy Based on Spatio-Temporally Controlled Nano Device Improves Therapy of Breast Cancer.
Ex Vivo Evaluation of Combination Immunotherapy Using Tumor-Microenvironment-on-Chip.
In Situ Cocktail Nanovaccine for Cancer Immunotherapy.
Intratumoral immunosuppression profiles in 11q-deleted neuroblastomas provide new potential therapeutic targets.
CD47 Blockade and Cowpea Mosaic Virus Nanoparticle In Situ Vaccination Triggers Phagocytosis and Tumor Killing
Combinatory Immunotherapy for Glioblastoma Treatment
Injectable Bioresponsive Gel Depot for Enhanced Immune Checkpoint Blockade.
Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next-Generatio
Artificial Transmembrane Oligopeptide-Integrated Interferon mRNA with Monoclonal Antibody to Improve Specificity and Eff
Strengthening the Combinational Immunotherapy from Modulating the Tumor Inflammatory Environment via Hypoxia‐Responsive
Modulatory effects of gut microbiome in cancer immunotherapy: A novel paradigm for blockade of immune checkpoint inhibit
Immunologic tumor microenvironment modulators for turning cold tumors hot
SHISA3 Reprograms Tumor‐Associated Macrophages Toward an Antitumoral Phenotype and Enhances Cancer Immunotherapy
Current status of immunotherapy against gastrointestinal cancers and its biomarkers: Perspective for precision immunothe
Peripheral blood clinical laboratory variables associated with outcomes following combination nivolumab and ipilimumab i
Effect of sex on the efficacy of patients receiving immune checkpoint inhibitors in advanced non-small cell lung cancer.
Highly expressed carbohydrate sulfotransferase 11 correlates with unfavorable prognosis and immune evasion of hepatocell
First‐line PD‐1/PD‐L1 inhibitors plus chemotherapy versus bevacizumab plus chemotherapy for advanced non‐squamous non‐sm
Smoking status combined with tumor mutational burden as a prognosis predictor for combination immune checkpoint inhibito
Cutaneous adverse events in 155 patients with metastatic melanoma consecutively treated with anti‐CTLA4 and anti‐PD1 com
Very Late Recurrence of Clear Cell Renal Cell Carcinoma With Pancreatic and Hepatic Metastases Showing Durable Response
Immune checkpoint inhibitor-induced myasthenia gravis, myocarditis, and myositis: A case report.
A Case Report of a Multisystemic Immune-Related Adverse Event Caused by Sintilimab in Combination With Thymosin Alpha-1.
Site‐specific response patterns, pseudoprogression, and acquired resistance in patients with melanoma treated with ipili
Neoadjuvant immunotherapy improves outlook in high‐risk melanoma
Rationalizing rules for immunotherapy combination trials: About time for precision immunotherapy.
Icaritin promotes tumor T-cell infiltration and induces antitumor immunity in mice.
Comparison between PD-1/PD-L1 inhibitors (nivolumab, pembrolizumab, and atezolizumab) in pretreated NSCLC patients: Evid
Safety and efficacy of immune checkpoint blockade in patients with advanced nonsmall cell lung cancer and brain metastas
Analysis of immune-related adverse events in gastrointestinal malignancy patients treated with immune checkpoint inhibit
An Efficient Combination Immunotherapy for Primary Liver Cancer by Harmonized Activation of Innate and Adaptive Immunity
Survival after neoadjuvant/induction combination immunotherapy vs combination platinum‐based chemotherapy for locally ad
Metastatic mucinous tubular and spindle cell carcinoma of the kidney responding to nivolumab plus ipilimumab.
Melanoma: Pathogenesis and Targeted Therapy.
Global Disproportionality Analysis of Adverse Event Reports on Interstitial Lung Diseases for Cancer-Targeted Therapies,
Gastric Carcinoma.
Combining nanomedicine and immune checkpoint therapy for cancer immunotherapy.
Systemic therapies in hepatocellular carcinoma: A revolution?
Immunotherapy Is Changing First-Line Treatment of Metastatic Renal-Cell Carcinoma.
Identification of fibrocyte cluster in tumors reveals the role in antitumor immunity by PD-L1 blockade.
Acute renal failure in patient with renal cell carcinoma after combination immune checkpoint inhibitor therapy
Clinically approved combination immunotherapy: Current status, limitations, and future perspective.
DISCERN: A Randomized Pilot Study Comparing Dual Versus Single Immune Checkpoint Blockade Plus Chemotherapy in PD-L1 Neg
Resistance to PD-1/PD-L1 immune checkpoint blockade in advanced non-small cell lung cancer.
Immunotherapy for head and neck cancer: Present and future.
The landscape of contemporary clinical trials for untreated metastatic clear cell renal cell carcinoma
A pathway-based mutation signature to predict the clinical outcomes and response to CTLA-4 inhibitors in melanoma.
Exploring the application of PD-1/PD-L1 inhibitors for ovarian cancer.
Enhancing programmed cell death protein 1 axis inhibition in head and neck squamous cell carcinoma: Combination immunoth
Immunotherapy for oncogenic-driven advanced non-small cell lung cancers: Is the time ripe for a change?
Cutaneous adverse events in lung cancer patients on the therapy based on PD-1/PD-L1 inhibitors: A prospective observatio
Cutaneous adverse effects of the immune checkpoint inhibitors.
Datasets for gene expression profiles of head and neck squamous cell carcinoma and lung cancer treated or not by PD1/PD-
Cancer immunotherapy: Opportunities and challenges in the rapidly evolving clinical landscape.
Immune checkpoint inhibitors for metastatic bladder cancer.
Targeted Therapy and Immunotherapy in Melanoma.
Tumour mutational burden as a biomarker for immunotherapy: Current data and emerging concepts.
Real-world outcomes with ipilimumab and nivolumab in advanced melanoma: a multicentre retrospective study.
PD-1/PD-L1 counterattack alliance: multiple strategies for treating triple-negative breast cancer
Ipilimumab plus nivolumab in patients with symptomatic melanoma brain metastasis requiring corticosteroids
Are immune checkpoint inhibitors a valid option for papillary renal cell carcinoma? A multicentre retrospective study.
Durable response to combination immunotherapy using nivolumab and ipilimumab in metastatic succinate dehydrogenase (SDH)
Immunologically active phenotype by gene expression profiling is associated with clinical benefit from PD-1/PD-L1 inhibi
Brain metastases from Merkel cell carcinoma: A nationwide retrospective study.
Circulating tumour DNA kinetics in recurrent/metastatic head and neck squamous cell cancer patients.
PP223 Single-cell RNA sequencing in metastatic lung cancer uncovers the efficacy of PD-1/PD-L1 inhibitors on immune cell
Prognostic significance of absolute lymphocyte count in patients with metastatic renal cell carcinoma receiving first-li
Nivolumab plus chemotherapy in first-line metastatic non-small-cell lung cancer: results of the phase III CheckMate 227
OP01-5 Combination immunotherapy targeting XBP1, CD138 and CS1 with cancer vaccine, checkpoint inhibitors, immune modula
Improving the Cost Efficiency of PD-1/PD-L1 Inhibitors for Advanced Urothelial Carcinoma: A Major Role for Precision Med
Predictive Role of Computed Tomography Texture Analysis in Patients with Metastatic Urothelial Cancer Treated with Progr
Research progress of tumor targeted drug delivery based on PD-1/PD-L1.
High pre-treatment neutrophil-to-lymphocyte ratio as a prognostic marker for worse survival in patients with recurrent/m
Programmed Death Receptor Ligand One Expression May Independently Predict Survival in Patients With Non-Small Cell Lung
Intracranial Control with Combined Dual Immune-Checkpoint Blockade and SRS for Melanoma and NSCLC Brain Metastases
Advanced endometrial cancer-The next generation of treatment: A society of gynecologic oncology journal club clinical co
Programmed death receptor-1/programmed death-ligand 1 inhibitors: Clinical progress and biomarker exploration in gastric
Clonal Deletion of Tumor-Specific T Cells by Interferon-γ Confers Therapeutic Resistance to Combination Immune Checkpoin
Targets for improving tumor response to radiotherapy.
Chimeric antigen receptor T cell therapy and other therapeutics for malignancies: Combination and opportunity.
PD-1/PD-L1 immune checkpoint blockade-based combinational treatment: Immunotherapeutic amplification strategies against
Peripheral Lymphocyte Count as a Surrogate Marker of Immune Checkpoint Inhibitor Therapy Outcomes in Patients with Non-S
Thinking Outside the Field: Two Cases of RT+ICI Synergy in Melanoma
Rational design of anti-GITR-based combination immunotherapy
The CD155/TIGIT Axis Promotes and Maintains Immune Evasion in Neoantigen-Expressing Pancreatic Cancer
Real-world outcomes with ipilimumab and nivolumab in advanced melanoma: a multicentre retrospective study.
Advancements in Stimulus-Responsive Co-Delivery Nanocarriers for Enhanced Cancer Immunotherapy.
Response to nivolumab combining radiotherapy and nimotuzumab in metastatic oral squamous cell carcinoma patient with str
Avelumab for the treatment of patients with Merkel cell carcinoma
The Emergence of Immune-checkpoint Inhibitors in Colorectal Cancer Therapy.
Recent Progress in Mutation-driven Therapy, Immunotherapy and Combination Therapy for the Treatment of Melanoma.
Recent Advances of Small Molecular Regulators Targeting G Protein- Coupled Receptors Family for Oncology Immunotherapy.
Immunotherapy in Combination with Chemotherapy for Triple-negative Breast Cancer.
Nivolumab and ipilimumab: immunotherapy for treatment of malignant melanoma.
Interview with Thomas Powles: The use of durvalumab in urothelial cancer - the latest strides in immuno-oncology.
Challenges faced when identifying patients for combination immunotherapy.
Combination immunotherapy in metastatic renal cell carcinoma. Are we leaving something back?
The Use of Combination Immunotherapies as Front-Line Therapy for Non-Small-Cell Lung Cancer
Development of shellfish allergy after exposure to dual immune checkpoint blockade.
Atypical patterns of response and progression in the era of immunotherapy combinations.
Dual immune checkpoint blockade in hepatocellular carcinoma: where do we stand?
Nivolumab Plus Ipilimumab in Non-Small-Cell Lung Cancer
Recent Clinical Trials of Immunotherapy in Non-Small-Cell Lung Cancer
Combination of bevacizumab and dual immunotherapy for extensive-disease small-cell lung cancer: a case report.
Successful Treatment of Immune Checkpoint Inhibitor–Induced Diabetes With Infliximab
PD-L1 ≥ 50% lung cancer refractory to PD-1 inhibition: the role of salvage chemo-immunotherapy combination.
The future of immunotherapy in advanced renal cell carcinoma: beyond PD-1/PD-L1 inhibitors.
Data from Dual immune checkpoint blockade induces analogous alterations in the dysfunctional CD8+ T cell and activated T
Data from Depletion of Effector Regulatory T Cells Associates with Major Response to Induction Dual Immune Checkpoint Bl
Data from Dual immune checkpoint blockade induces analogous alterations in the dysfunctional CD8+ T cell and activated T
Genetically Defined Syngeneic Mouse Models of Ovarian Cancer as Tools for the Discovery of Combination Immunotherapy
Dual Immune Checkpoint Blockade Induces Analogous Alterations in the Dysfunctional CD8+ T-cell and Activated Treg Compar
Clofazimine Reduces Side Effects from Dual Immune Checkpoint Blockade
A Phase I Trial of Regional Mesothelin-Targeted CAR T-cell Therapy in Patients with Malignant Pleural Disease, in Combin
Depletion of Effector Regulatory T Cells Associates with Major Response to Induction Dual Immune Checkpoint Blockade.
Data from CD4<sup>+</sup> T Cells Mediate MHC-Deficient Tumor Rejection and Endothelial Cell Reprogramming
Intratumoral STING Activation with T-cell Checkpoint Modulation Generates Systemic Antitumor Immunity
Intratumoral CD8+ T-cell Apoptosis Is a Major Component of T-cell Dysfunction and Impedes Antitumor Immunity
Predictive Biomarkers for Checkpoint Immunotherapy: Current Status and Challenges for Clinical Application.
Deep Sequencing of T-cell Receptor DNA as a Biomarker of Clonally Expanded TILs in Breast Cancer after Immunotherapy
Tumor Burden Affects Efficacy of Combination Immunotherapy
DGKA Mediates Resistance to PD-1 Blockade
Concurrent PD-1 Blockade Negates the Effects of OX40 Agonist Antibody in Combination Immunotherapy through Inducing T-ce
Site-Dependent Immune Escape Due to Impaired Dendritic Cell Cross-Priming
Immune Profiling and Quantitative Analysis Decipher the Clinical Role of Immune-Checkpoint Expression in the Tumor Immun
Tumor Cell–Intrinsic USP22 Suppresses Antitumor Immunity in Pancreatic Cancer
Abstract C064: Tumor Ecosystem and Microbiome Features Associated with Efficacy from Avelumab-based Multimodal Therapy i
Recent Advances in Systemic Therapy for Hepatocellular Carcinoma in an Aging Society: 2020 Update.
Incidence of Hyper Progressive Disease in Combination Immunotherapy and Anti-Programmed Cell Death Protein 1/Programmed
Abstract PR07: Developing syngeneic NOD tumor models to profile immunotoxicity and antitumor immunity in response to can
Interleukin 10-Mediated Response and Correlated Anemia in a Patient with Advanced Non-Small Cell Lung Carcinoma
Personalized Immuno-Oncology
Scientific Rationale for Combination Immunotherapy of Hepatocellular Carcinoma with Anti-PD-1/PD-L1 and Anti-CTLA-4 Anti
Chinese Multidisciplinary Expert Consensus on Immune Checkpoint Inhibitor-Based Combination Therapy for Hepatocellular C
Clinical Trials in Metastatic Uveal Melanoma: Immunotherapy.
Unusual Presentation of a Rare Case of Immunotherapy Combination-Induced Encephalitis: A Case Report.
Predictive Factors Associated with Long-Term Response to Combination Immunotherapy in Patients with Untreated Advanced N
Complete Remission of Metastatic Melanoma of the Scalp Following Treatment With Nivolumab Plus Relatlimab.
PD1/PDL-1 Inhibitors: Emerging Hope for Bladder Cancer
IMMUNOTHERAPY TREATMENT AGAINST CERVICAL CANCER.
Preclinical Evaluation and Pilot Clinical Study of CD137 PET Radiotracer for Noninvasive Monitoring Early Responses of I
Double Immune Checkpoint Blockade in Renal Cell Carcinoma
Neoadjuvant immunotherapy in breast cancer: a paradigm shift?
Genomic biomarkers to predict response to atezolizumab plus bevacizumab immunotherapy in hepatocellular carcinoma: Insig
Targeting CTLA-4 in Cancer: Biological Insights with a Focus on Renal Cell Carcinoma
Results of treatment of metastatic melanoma in real clinical practice: optimal choice and sequence of drug administratio
FcγR-Binding Is an Important Functional Attribute for Immune Checkpoint Antibodies in Cancer Immunotherapy.
AHCC®, a Standardized Extract of Cultured Lentinula Edodes Mycelia, Promotes the Anti-Tumor Effect of Dual Immune Checkp
Changes of peripheral T cell subsets in melanoma patients with immune-related adverse events.
Bispecific antibodies targeting CTLA-4: game-changer troopers in cancer immunotherapy.
A combined radio-immunotherapy regimen eradicates late-stage tumors in mice.
Heterogeneity and the tumor microenvironment in neuroendocrine prostate cancer
- **Journal:** Russian Journal of Cardiology - **Source:** semanticscholar - **Content Type:** Metadata only
Combination immune checkpoint inhibitor therapy nivolumab and ipilimumab associated with multiple endocrinopathies
Late-Onset Immunotherapy Toxicity and Delayed Autoantibody Changes: Checkpoint Inhibitor–Induced Raynaud's-Like Phe
Safety of Nivolumab plus Low-Dose Ipilimumab in Previously Treated Microsatellite Instability-High/Mismatch Repair-Defic
Prolonging Survival: The Role of Immune Checkpoint Inhibitors in the Treatment of Extensive-Stage Small Cell Lung Cancer
Dual targeting of TIGIT and VISTA in non-small-cell lung cancer immunotherapy.
The MHC-I-dependent neoantigen presentation pathway predicts response rate to PD-1/PD-L1 blockade.
Evidence for Early Stage Anti-Tumor Immunity Elicited by Spatially Fractionated Radiotherapy-Immunotherapy Combinations
Experience of using 1<sup>st</sup> line combination immunotherapy in patients with metastatic renal cell carcinoma
Enhancing cancer care with improved checkpoint inhibitors: a focus on PD-1/PD-L1.
Acute Interstitial Nephritis and Renal Tubular Acidosis Associated with Bispecific Anti-T Cell Immunoreceptor with Ig an
Health Care Resource Utilization and Costs in First-Line Treatments for Patients with Metastatic Melanoma in the United
[Renal injury during combination immunotherapy (ipilimumab + nivolumab) in patients with metastatic renal cell cancer wh
A multidisciplinary approach with immunotherapies for advanced hepatocellular carcinoma
The promising immune checkpoint LAG-3: from tumor microenvironment to cancer immunotherapy.
Current and future immunotherapy approaches in ovarian cancer
Companion diagnostics-a tool to improve pharmacotherapy.
Combination immunotherapy in metastatic urothelial cancer: time for the next step?
Plasma cytokines interleukin-18 and C-X-C motif chemokine ligand 10 are indicative of the anti-programmed cell death pro
Combination therapy for metastatic renal cell carcinoma.
Immunotherapy of patients with metastatic melanoma.
Rational combinations of immunotherapy for pancreatic ductal adenocarcinoma.
Patterns and genomic correlates of PD-L1 expression in patients with biliary tract cancers
A comprehensive pan-cancer analysis of CD274 gene amplification, tumor mutation burden, microsatellite instability, and
Response to the rechallenge of combination immunotherapy in a patient with late-stage gastric cancer: case report.
Immune checkpoint blockade for advanced non-small cell lung cancer: challenging clinical scenarios
Prolonged tumor response associated with sequential immune checkpoint inhibitor combination treatment and regorafenib in
Combinational immunotherapy based on immune checkpoints inhibitors in small cell lung cancer: is this the beginning to r
Shining light on advanced NSCLC in 2017: combining immune checkpoint inhibitors.
Immune checkpoint inhibitors for metastatic bladder cancer
Tumor mutation burden in lung cancer: a new predictive biomarker for immunotherapy or too soon to tell?
Efficacy and safety of anti-programmed cell death protein 1 antibody combination therapy in patients with advanced exper
Efficiency and toxicity of nab-paclitaxel and camrelizumab in the second or above line treatment of advanced non-small c
Measuring tumor mutation burden in non-small cell lung cancer: tissue versus liquid biopsy
Tumor mutational burden in non-small cell lung cancer-the pathologist's point of view.
Prognostic roles of hematological indicators in programmed cell death protein 1/programmed cell death ligand 1 inhibitor
Association between changes in thioredoxin reductase and other peripheral blood biomarkers with response to PD-1 inhibit
Incidence and severity of immune-related hepatitis after dual checkpoint therapy is linked to younger age independent of
Tumor mutational burden as predictive factor of response to immunotherapy
Association of thyroid transcription factor-1 (TTF-1) expression with efficacy of PD-1/PD-L1 inhibitors plus pemetrexed
Advances in clinical trials of targeted therapy and immunotherapy of lung cancer in 2018
Current situation of programmed cell death protein 1/programmed cell death ligand 1 inhibitors in advanced triple-negati
CD80 and CD86: expression and prognostic value in newly diagnosed glioblastoma
LAG-3 and PD-1/PD-L1 inhibitors might become a promising treatment for small cell lung cancer
Recent Advancements in Immunotherapy for the Treatment of Metastatic Breast Cancer.
The sound and surprise: overlapping meta-analyses on the topic of safety and efficacy of PD-1 and PD-L1 inhibitors in th
Novel Immune Modulatory Agents in the Treatment of Non-small Cell Lung Cancer.
Microfluidic Protocols for the Assessment of Anticancer Therapies in 3D Tumor-Stromal Cocultures.
[Modern concepts of systemic treatment for adjuvant and palliative treatment of locally advanced or metastasized esophag
Breast Cancer Immunotherapy: A Team Science Approach.
[Advanced bladder cancer : From chemo- to immunotherapy].
HER2-Positive Breast Cancer Immunotherapy: A Focus on Vaccine Development.
Progress of PD-1/PD-L1 inhibitor combination therapy in immune treatment for HER2-positive tumors.
[Immunotherapy as modern tumor treatment].
Peri-tumor administration of controlled release anti-CTLA-4 synergizes with systemic anti-PD-1 to induce systemic antitu
TIGIT: a novel immunotherapy target moving from bench to bedside.
Testing Cancer Immunotherapeutics in a Humanized Mouse Model Bearing Human Tumors.
Mechanistic insights into immune checkpoint inhibitor-related hypophysitis: a form of paraneoplastic syndrome.
Modeling tumour heterogeneity of PD-L1 expression in tumour progression and adaptive therapy.
Immune checkpoint inhibitor-induced hepatitis injury: risk factors, outcomes, and impact on survival.
Anti-PD-1/PD-L1 immunotherapy in conversion treatment of locally advanced hepatocellular carcinoma.
Exploring novel immunotherapy in advanced esophageal squamous cell carcinoma: Is targeting TIGIT an answer?
Combination therapy with PD-1 or PD-L1 inhibitors for cancer.
Predictive factors in the treatment of oral squamous cell carcinoma using PD-1/PD-L1 inhibitors.
Emerging combination immunotherapy strategies for breast cancer: dual immune checkpoint modulation, antibody–drug conjug
Comparative safety and survival outcomes of immune checkpoint inhibitors in brain metastases from lung cancer: a propens
Effectiveness of PD-1/PD-L1 inhibitors in the treatment of lung cancer: Brightness and challenge.
Immunotherapy for Gastric Cancer: A Focus on Immune Checkpoints.
ESIRA, a novel framework integrating efficacy and safety for evaluating first-line treatments in advanced hepatocellular
Combination immunotherapy strategies for glioblastoma.
Complete response of hereditary leiomyomatosis and renal cell cancer (HLRCC)-associated renal cell carcinoma to nivoluma
Checkpoint Inhibitors for the Treatment of Renal Cell Carcinoma.
Tumor Mutation Burden as a Potential Biomarker for PD-1/PD-L1 Inhibition in Advanced Non-small Cell Lung Cancer.
Mathematical Modelling and Optimization of Medication Regimens for Combination Immunotherapy of Breast Cancer.
Clinical Development of PD-1/PD-L1 Inhibitors in Breast Cancer: Still a Long Way to Go.
Systemic Management of Advanced Adrenocortical Carcinoma.
Immune Checkpoint Inhibitor Toxicity.
Treating Colorectal Cancer with Immunotherapy: Implications for Single versus Combination Therapy.
Role of CTLA Inhibition in Management of Non-Small Cell Lung Cancer.
Recent Advances in Systemic Therapies for Advanced Hepatocellular Carcinoma
Combination Immunotherapy in Non-small Cell Lung Cancer.
Spectrum and Clinical Activity of PD-1/PD-L1 Inhibitors: Regulatory Approval and Under Development.
The Treatment Landscape of Advanced Hepatocellular Carcinoma.
Immune Checkpoint Inhibitors in Locally Advanced, Unresectable, and Metastatic Upper Gastrointestinal Malignancies.
Application of Immune Checkpoint Inhibitors in Gynecological Cancers: What Do Gynecologists Need to Know before Using Im
Increase in Efficacy of Checkpoint Inhibition by Cytokine-Induced-Killer Cells as a Combination Immunotherapy for Renal
Neoadjuvant Immunotherapy for Muscle-Invasive Bladder Cancer.
Injectable Polypeptide Hydrogel Depots Containing Dual Immune Checkpoint Inhibitors and Doxorubicin for Improved Tumor I
[Advances in immunotherapy for neuroendocrine neoplasms].
[Role of PD-1/PD-L1 in microenvironment of breast cancer].
Research advances in radiotherapy combined with immune checkpoint blockade
Genetic characteristics of platinum-sensitive ovarian clear cell carcinoma
Screening for the drugs that increase the efficacy of poly(ADP-ribose) polymerase inhibitor by the FDA-approved compound
Molecular cytometry identifies a wide range of translationally relevant markers in tumor and peripheral immune cells of
CTLA‑4 blockade combined with 5‑aza‑2'‑deoxycytidine enhances the killing effect of MAGE‑A family common antigen pe
The combination therapy with the cytotoxic T lymphocyte-associated antigen-4 and programmed death 1 antibody-induced ast
Bronchiolitis obliterans after combination immunotherapy with pembrolizumab and ipilimumab
Current and emerging trends in prostate cancer immunotherapy.
Genomic Sequencing for Bladder Urothelial Carcinoma and Its Clinical Implications for Immunotherapy
Current trends in the treatment of malignant melanoma
COMBINATION IMMUNOTHERAPY IN METASTATIC RENAL CELL CARCINOMA
Immunotherapy in Advanced Lung Cancer.
Immunotherapy in Cancer Treatment: Harnessing the Power of the Immune System
NCCN Guidelines Updates: Management of Metastatic Colorectal Cancer.
Role of Immunotherapy in the Treatment of Squamous Cell Carcinoma of the Anal Canal
The Potential Applicability of Single-Domain Antibodies (VHH): From Checkpoint Blockade to Infectious Disease Therapy
Author Response: DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen
eLife Assessment: DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen
DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation
eLife Assessment: DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen
DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation
DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation
DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation
Advanced fumarate hydratase-deficient renal cell carcinoma responding to combination immune checkpoint inhibitors.
Combination immunotherapy: a road map The Harvard community has made this article openly available. Please share how thi
Combination immunotherapy in renal cell carcinoma.
Characteristics of the immune microenvironment associated with RRM2 expression and its application to PD-L1/PD-1 inhibit
[Combination Therapy of Immune Checkpoint Inhibitors].
Future Research Goals in Immunotherapy.
Favorable clinical impact of histological subtype with non-small cell carcinoma-not otherwise specified in patients with
ABCB11 accumulated in immature tertiary lymphoid structures participates in xenobiotic metabolic process and predicts re
Cancer immunotherapy: A paradigm shift in the treatment of advanced urologic cancers.
The impact of CDCA5 expression on the immune microenvironment and its potential utility as a biomarker for PD-L1/PD-1 in
The co-inhibitory immune checkpoint proteins B7-H1(PD-L1) and B7-H4 in high grade glioma: From bench to bedside.
Combination of CTLA-4 blockade with MUC1 mRNA nanovaccine induces enhanced anti-tumor CTL activity by modulating tumor m
A signature of enhanced proliferation associated with response and survival to anti-PD-L1 therapy in early-stage non-sma
A2AR as a key target for immune microenvironment remodeling in prostate cancer.
Combination Immunotherapy of MUC1 mRNA Nano-vaccine and CTLA-4 Blockade Effectively Inhibits Growth of Triple Negative B
Neoadjuvant combination immunotherapy in MSI/dMMR colorectal cancer.
Development and Preliminary Clinical Activity of PD-1-Guided CTLA-4 Blocking Bispecific DART Molecule
Immunotherapy for Prostate Cancer-Why Now?
HLA-A*03 and response to immune checkpoint blockade in cancer: an epidemiological biomarker study.
Thermosensitive Hydrogel-Mediated Chemo-Photothermal Combined Immunotherapy for Triple-Negative Breast Cancer.
Programmable Porous Silicon Microparticles for Temporally Staged Drug Delivery in Combination Cancer Immunotherapy.
Subcutaneous Nanodisc Vaccination with Neoantigens for Combination Cancer Immunotherapy
Physical- and Chemical-Dually ROS-Responsive Nano-in-Gel Platforms with Sequential Release of OX40 Agonist and PD-1 Inhi
In Situ Transformable Photothermal Targeting Chimeras for Spatiotemporally Controllable Protein Degradation and Combinat
Catalytic Intermolecular Asymmetric [2π + 2σ] Cycloadditions of Bicyclo[1.1.0]butanes: Practical Synthesis of Enantioenr
Multifunctional Lipid Bilayer Nanocarriers for Cancer Immunotherapy in Heterogeneous Tumor Microenvironments, Combining
The future of cancer treatment: immunomodulation, CARs and combination immunotherapy
Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune res
Programmed cell death ligand-1 expression in tumor and immune cells is associated with better patient outcome and decrea
Dissecting the mechanisms of immune checkpoint therapy
Approaches to treat immune hot, altered and cold tumours with combination immunotherapies.
Immunotherapy for ovarian cancer: towards a tailored immunophenotype-based approach
Optimizing combination immunotherapy in lung cancer.
Neoadjuvant versus adjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma.
First-in-human phase I open-label study of the anti–TIM-3 monoclonal antibody INCAGN02390 in patients with select advanc
Advanced Renal Cell Cancer Combination Immunotherapy Clinical Trial (ARCITECT; HCRN GU 22-587)
Computed Tomography Texture Analysis for Predicting Clinical Outcomes in Patients With Metastatic Renal Cell Carcinoma T
A lipid/PLGA nanocomplex to reshape tumor immune microenvironment for colon cancer therapy
The quadruple immunotherapy for colorectal cancer (QuICC) trial for mismatch repair-proficient metastatic colorectal can
Advancement of anti‐LAG ‐3 in cancer therapy
Dual blockade of CXCL12‐CXCR4 and PD‐1–PD‐L1 pathways prolongs survival of ovarian tumor–bearing mice by prevention of i
Plasma sPD-L1 and VEGF levels are associated with the prognosis of NSCLC patients treated with combination immunotherapy
MP21-03 CD-70 BLOCKADE AS A NOVEL IMMUNOTHERAPY FOR THE TREATMENT OF CLEAR-CELL RENAL CELL CARCINOMA
Bronchiolitis after Combination Immunotherapy With Ipilimumab and Nivolumab in a Melanoma Patient.
New therapies for brain metastases: an update.
Current and future drug combination strategies based on programmed death-1/programmed death-ligand 1 inhibitors in non-s
Autoimmune Myocarditis Caused by Immune Checkpoint Inhibitors Treated With Antithymocyte Globulin
Breast cancer immunology and immunotherapy: targeting the programmed cell death protein-1/programmed cell death protein
Combination immunotherapies implementing adoptive T-cell transfer for advanced-stage melanoma
New-onset toxicity with programmed death-1 inhibitor rechallenge.
Immunotargeted therapy in melanoma: patient, provider preferences, and willingness to pay at an academic cancer center.
Adjuvant systemic therapy in high-risk melanoma.
Successful treatment with intralesional talimogene laherparepvec in two patients with immune checkpoint inhibitor-refrac
Immune privilege: failure of immunotherapy in controlling metastatic cutaneous melanoma to the eye.
Durable Responses in Patients With Advanced Cholangiocarcinoma on Sequential Dual-agent Immunotherapy After Progressing
Targeting the programmed cell death-1 pathway in breast and ovarian cancer
Combination Immunotherapy for Pancreatic Cancer Appears Promising in Johns Hopkins Platform Trial
New strategies for the management of triple-negative breast cancer.
Emerging Nonsurgical Therapies for Locally Advanced and Metastatic Nonmelanoma Skin Cancer
NRF2–COX2–PGE2 axis drives immune cold tumors and predicts resistance to combination immunotherapy in hepatocellular car
Development of Poliosis Following Checkpoint Inhibitor Treatment for Cutaneous Melanoma.
First-line combination immunotherapy for metastatic non-small cell lung cancer
Insight of pancreatic cancer: recommendations for improving its therapeutic efficacy in the next decade
Neuron - specific enolase predicts the prognosis in advanced small cell lung cancer patients treated with first-line PD-
Combination immunotherapy in genitourinary malignancies.
Advances in treatment of metastatic renal cell carcinoma.
Indoleamine-2,3-Dioxygenase in Non–Small Cell Lung Cancer: A Targetable Mechanism of Immune Resistance Frequently Coexpr
Sarcomatoid and Rhabdoid Renal Cell Carcinoma: Clinical, Pathologic, and Molecular Genetic Features.
Immunotherapy in kidney cancer
Depletion of effector regulatory T cells drives major response to induction dual immune checkpoint blockade
Combined PD-L1 and TIM-3 blockade improves the expansion of fit human CD8+ antigen-specific T cells for adoptive immunot
Tumour neoantigen heterogeneity thresholds provide a time window for combination immunotherapy.
Impact of PD‐L1, transforming growth factor‐β expression and tumor‐infiltrating CD8+ T cells on clinical outcome of pati
Real-world evidence in metastatic renal cell carcinoma.
Nomogram for Predicting Survival Post-Immune Therapy in Cholangiocarcinoma Based on Inflammatory Biomarkers
Temozolomide overcoming resistance to immune checkpoint inhibitors in relapsed/refractory metastatic melanoma? Insights
D-dimer levels predict the treatment efficacy and prognosis of esophageal squamous cell carcinoma treated with PD-1/PD-L
Evaluation of immune checkpoint inhibitor-associated hepatotoxic adverse events: A pharmacovigilance analysis based on t
SMARCB1/INI-1-Deficient sinonasal carcinoma demonstrates a poor prognosis but favorable clinical outcomes after PD-1/PD-
Cutaneous Immune-Related Adverse Events (irAEs) to Immune Checkpoint Inhibitors: A Dermatology Perspective on Management
Combination of immunotherapy with targeted therapies in advanced non-small cell lung cancer (NSCLC).
The regulation of the PD-1/PD-L1 pathway in imiquimod-induced chronic psoriasis itch and itch sensitization in mouse.
Effectiveness of fourth-line dual immunotherapy in hepatocellular carcinoma with simultaneous steroid administration for
The evolving immuno-oncology landscape in advanced lung cancer: first-line treatment of non-small cell lung cancer.
Current Clinical Progress of PD-1/PD-L1 Immunotherapy and Potential Combination Treatment in Non-Small Cell Lung Cancer.
Dramatic response of refractory metastatic squamous cell carcinoma of the skin with cetuximab/pembrolizumab.
Combination targeted and immune therapy in the treatment of advanced melanoma: a valid treatment option for patients?
Radiotherapy may augment response to immunotherapy in metastatic uveal melanoma patients.
Management of metastatic cutaneous melanoma: updates in clinical practice.
The progress and challenge of anti-PD-1/PD-L1 immunotherapy in treating non-small cell lung cancer.
Retrospective study of the combination of TP and PF regimens with or without immune checkpoint inhibitors for the first-
The efficacy of combination immunotherapy with ipilimumab plus nivolumab in metastatic myxofibrosarcoma.
Efficacy and safety of nab-paclitaxel or combined nab-paclitaxel and immune checkpoint inhibitors in relapsed small-cell
Current status and advances of immunotherapy in nasopharyngeal carcinoma.
Intratumoral Administration of the Immunotherapeutic Combination Anti-ctla4, Anti-cd137 and Anti-ox40: Comparison to Sys
DSP-7888, a Novel Cocktail Design of WT1 Peptide Vaccine, and Its Combinational Immunotherapy with Immune Checkpoint-Blo
Bronchoscopic intratumoural therapies for non-small cell lung cancer
The influence of radiation in the context of developing combination immunotherapies in cancer
Combination immunotherapy strategies for triple-negative breast cancer: current progress and barriers within the pharmac
Safety evaluation of durvalumab for the treatment of non-small-cell lung cancer.
Harnessing the immune system for the treatment of melanoma: current status and future prospects.
Combination immunotherapy for pancreatic cancer: challenges and future considerations.
Atezolizumab for the treatment of non-small cell lung cancer
Immunotherapy of High Risk Non-Muscle Invasive Bladder Cancer.
First-line immune checkpoint inhibitor-based combinations in unresectable hepatocellular carcinoma: current management a
Highlighting novel targets in immunotherapy for liver cancer
Insights into the mechanisms of serplulimab: a distinctive anti-PD-1 monoclonal antibody, in combination with a TIGIT or
Patterns of immune-related adverse events in patients treated for various cancer types with immune checkpoint inhibitors
Durvalumab for the treatment of non-small cell lung cancer
CD47 is a direct target of SNAI1 and ZEB1 and its blockade activates the phagocytosis of breast cancer cells undergoing
Therapeutic efficacy of combined vaccination against tumor pericyte-associated antigens DLK1 and DLK2 in mice.
Combined immune checkpoint blockade increases CD8+CD28+PD-1+ effector T cells and provides a therapeutic strategy for pa
Generation of highly activated, antigen-specific tumor-infiltrating CD8+ T cells induced by a novel T cell-targeted immu
Angiotensin-converting enzyme (ACE) inhibitor prescription affects non-small-cell lung cancer (NSCLC) patients response
Combinatorial immunotherapeutic approaches to restore the function of anergic tumor-reactive cytotoxic CD8+ T cells.
Overcoming the resistance of hepatocellular carcinoma to PD-1/PD-L1 inhibitor and the resultant immunosuppression by CD3
Cancer vaccines: Enhanced immunogenic modulation through therapeutic combinations.
Firing up the cold tumors by targeting Vps34.
Combination immunotherapy with ipilimumab and nivolumab in patients with advanced adrenocortical carcinoma: a subgroup a
PD-1/PD-L1 immune checkpoint inhibitors in glioblastoma: clinical studies, challenges and potential
Combination Immunotherapy of Oncolytic Flu-Vectored Virus and Programmed Cell Death 1 Blockade Enhances Antitumor Activi
DNA damage response as biomarkers informing a precision medicine approach to bladder cancer: what are the next steps?
Combination immunotherapy for cancer.
Defining the optimal murine models to investigate immune checkpoint blockers and their combination with other immunother
Immune escape to PD-L1/PD-1 blockade: seven steps to success (or failure)
Design and conduct of early clinical studies of immunotherapy agent combinations: recommendations from the task force on
Early peripheral T-cell responses predict oncological outcome to checkpoint immune blockade in metastatic melanoma
SP6.1.4 Novel methods to enhance anti-tumour immunity in oesophageal adenocarcinoma; hypofractionated radiotherapy may b
Combined programmed cell death protein 1 and cytotoxic T-lymphocyte associated protein 4 blockade in an international co
72206 - Overall Survival after Isolated Hepatic Perfusion in Combination with Ipilimumab and Nivolumab in Patients with
P537 Steroid use in patients with immune checkpoint inhibitor colitis
Hyperthermic Intrathoracic Chemotherapy (HITOC) Improves Malignant Pleural Mesothelioma Control Through a Tumor Specific
Unresectable cardiac metastasis from melanoma responds well to combination immunotherapy-a case report.
Current status and perspectives of immune checkpoint inhibitors for colorectal cancer.
First-line nivolumab plus ipilimumab with or without chemotherapy for Japanese patients with non-small cell lung cancer:
Modeling the effects of combination immunotherapy on triple-negative breast cancer in syngeneic mice from PET imaging of
The present status and future prospects of peptide-based cancer vaccines.
Role of dendritic cell metabolic reprogramming in tumor immune evasion.
TAMI-23. ANTIBODY COCKTAIL IMMUNOTHERAPY FOR GLIOBLASTOMA BY DUAL TARGETING OF IL-6 AND CD40
IMMU-19. EVALUATING EFFECTS OF REVERSING DISTINCT FACETS OF IMMUNOSUPPRESSION IN EXPERIMENTAL GBM
KS05.5.A REPETITIVE INTRACRANIAL INJECTION OF NATURAL KILLER CELLS ENGINEERED WITH A HER2-TARGETED CHIMERIC ANTIGEN RECE
HGG-01. DURABLE RESPONSE TO IMMUNOTHERAPY IN AN ADOLESCENT PATEINT WITH CONSTITUTIONAL MISMATCH REPAIR DEFICIENCY CMMRD
MMAP-07 IMPACT OF SINGLE AND DUAL IMMUNE CHECKPOINT BLOCKADE ON RISK OF RADIATION NECROSIS AMONG PATIENTS WITH BRAIN MET
RTHP-10. IMPACT OF COMBINATION IMMUNOTHERAPY WITH TUMOR TREATING FIELDS THERAPY IN A GLIOMA COHORT
TMIC-63. DUAL IMMUNE CHECKPOINT BLOCKADE IN A NOVEL EGFR-DRIVEN MURINE GLIOMA MODEL INCREASES PERIPHERAL T CELL PROLIFER
Adverse neurologic events of immune checkpoint inhibitor monotherapy vs. combination therapy for melanoma.
CTIM-12. DUAL IMMUNE CHECKPOINT BLOCKADE FOR SURGICALLY ACCESSIBLE RECURRENT GLIOBLASTOMA: CLINICAL AND MOLECULAR OUTCOM
47TCF1+ CD4+ T cells mediate response to anti-CTLA-4 therapy in a sarcomatoid RCC mouse model
Circulating Tumor DNA Predicts Outcome from First-, but not Second-line Treatment and Identifies Melanoma Patients Who M
Transcriptomic Profiling of MSI-H/dMMR Gastrointestinal Tumors to Identify Determinants of Responsiveness to Anti–PD-1 T
PD-1 Inhibitors: Do they have a Future in the Treatment of Glioblastoma?
Modification of Extracellular Matrix Enhances Oncolytic Adenovirus Immunotherapy in Glioblastoma
Capturing Hyperprogressive Disease with Immune-Checkpoint Inhibitors Using RECIST 1.1 Criteria
Designing Clinical Trials for Combination Immunotherapy: A Framework for Glioblastoma
Circulating Tumor Cell Subtypes and T-cell Populations as Prognostic Biomarkers to Combination Immunotherapy in Patients
Combination Immunotherapy with Cytotoxic T-Lymphocyte-Associated Antigen-4 and Programmed Death Protein-1 Inhibitors Pre
Intratumoral CD16+ macrophages are associated with clinical outcomes of patients with metastatic melanoma treated with c
Eganelisib, a First-in-Class PI3Kγ Inhibitor, in Patients with Advanced Solid Tumors: Results of the Phase 1/1b MARIO-1
Abstract 566: High dimensional single cell analysis predicts response to anti-PD-1 immunotherapy
Abstract 3678: Muc4 nanovaccine and checkpoint blockade based combination immunotherapy for pancreatic cancer
Abstract 3778: Combination immunotherapy intercepts murine pancreatic cancer progression
Abstract 2766: Resistance to radiotherapy and PD-L1 blockade is mediated by TIM-3 upregulation in anti-PD-L1 refractory
Abstract 2822: Low intestinal microbial diversity is associated with severe immune-related adverse events and lack of re
Abstract 611: PD-1-based combination immunotherapy reinvigorates CD8+ T cells in metastatic pancreatic cancer patients w
Abstract 4843: TP53-stabilization with APR-246 enhances antitumor effects of immune checkpoint blockade in preclinical m
Abstract 2778: Mapping the extracellular pH gradient of colorectal cancer after immuno-thermal ablation
Abstract 4286: TGF-β signature is a therapeutic biomarker for combination immunotherapy for hepatocellular carcinoma
Abstract 2257: Phase II study of dual immune checkpoint blockade (ICB) with durvalumab (Durva) plus tremelimumab (T) fol
Abstract CT078: Tumor mutational burden (TMB) as a biomarker for clinical benefit from dual immune checkpoint blockade w
Abstract CT077: Nivolumab (nivo) + ipilimumab (ipi) vs platinum-doublet chemotherapy (PT-DC) as first-line (1L) treatmen
Abstract 6189: Development of an anti hepatocellular carcinoma CAR T strategy targeting PDL1
Abstract 2389: In vivo multiphoton autofluorescence imaging is sensitive to CD8 T cell and tumor cell metabolic changes
Abstract CT520: The safety summary of the phase 1a/b trial of QL1706, a novel dual immune checkpoint blockade containing
Abstract 519: Hyperprogression in follicular thyroid cancer treated with combination immunotherapy
Abstract CT180: Safety and efficacy of vibostolimab (vibo) plus pembrolizumab (pembro) and coformulation of vibo/pembro
Abstract 4393: Tumor volumetric analysis to correlate disease burden with response to dual immune checkpoint blockade in
Abstract 2281: Dual immune checkpoint blockade induces analogous alterations in the dysfunctional CD8+ T cell and activa
Abstract 88: Novel cell-based bioassays enable preclinical animal studies during immuno-oncology drug development
Abstract B12: Immune checkpoint blockade to improve T cell infiltration and function in colorectal cancer
Abstract 6642: Rapid tissue donation identifies LAG3 as a potential therapeutic target for ALK fusion positive lung canc
Abstract CT037: Nivolumab plus ipilimumab vs chemotherapy as first-line treatment for advanced gastric cancer/gastroesop
Abstract 6464: Spatial mapping of the tumor microenvironment for combination therapy design
Abstract B058: VEGF inhibition enhances immune checkpoint blockade efficacy in ovarian cancer
Abstract C064: Chronic platinum exposure induces cell-intrinsic type1 interferon/STING pathway activation in homologous
- **DOI:** 10.1158/1538-7445.panca22-c013 - **Authors:** Noah Cheng, N. Markosyan, R. Vonderheide - **Year:** 2022 - **J
Abstract OT1-18-04: A phase II study of dual immune checkpoint blockade (ICB) plus bicalutamide to enhance thymic T-cell
Abstract A098: Single nuclear profiling reveals type I IFN-mediated immune remodeling in platinum-refractory HRD-mutant
Abstract IA005: Generating T cell responses against pancreatic cancer
Abstract 2257: Phase II study of dual immune checkpoint blockade (ICB) with durvalumab (Durva) plus tremelimumab (T) fol
Abstract OT2-08-02: SOLTI-1907 ATREZZO: Targeting hormonal receptor negative (HR-) or PAM50 non-luminal disease with ate
Abstract 4843: TP53-stabilization with APR-246 enhances antitumor effects of immune checkpoint blockade in preclinical m
Abstract 4491: Association of intratumoral immunologic profile with overall survival in metastatic pancreatic cancer pat
Abstract 4063: Single cell immune profiling of patients with advanced biliary cancers treated with combination checkpoin
Abstract PO3-06-09: A phase II study of nivolumab plus ipilimumab and androgen receptor antagonist bicalutamide to stimu
Targeting of CD40 and PD-L1 Pathways Inhibits Progression of Oral Premalignant Lesions in a Carcinogen-induced Model of
Abstract P1-16-08: Response to subsequent therapy after dual immune checkpoint blockade in metastatic breast cancer
Abstract CT102: APACHE: An open label, randomized, phase II study of Durvalumab (Durva), alone or in combination with Tr
Artificial Intelligence-Detected Tumor-Infiltrating Lymphocytes and Outcomes in Anti-PD-1-Based Treated Melanoma.
Nivolumab and Ipilimumab in Advanced Mismatch Repair-Deficient/Microsatellite Instability-High Noncolorectal Cancers: A
Anti-CTLA-4 m2a Antibody Exacerbates Cardiac Injury in Experimental Autoimmune Myocarditis Mice By Promoting Ccl5-Neutro
Immunostimulatory TLR7 agonist-nanoparticles together with checkpoint blockade for effective cancer immunotherapy.
Eosinophil may be a predictor of immune-related adverse events induced by different immune checkpoint inhibitor types: A
Systemic therapy for Asian patients with advanced BRAF V600-mutant melanoma in a real-world setting: A multi-center retr
Design and Characterization of Prodrugged Anti-CTLA-4 Antibodies.
Toxicity and efficacy of Gamma Knife radiosurgery for brain metastases in melanoma patients treated with immunotherapy o
Endocrine-related adverse events associated with immune-checkpoint inhibitors in patients with melanoma.
TERT mutations correlate with higher TMB value and unique tumor microenvironment and may be a potential biomarker for an
Enhanced CTLA-4 blockade anti-tumor immunity with APG-157 combination in a murine head and neck cancer.
Timing and type of immune checkpoint therapy affect the early radiographic response of melanoma brain metastases to ster
Determinants of overall survival in patients with metastatic uveal melanoma.
Local checkpoint inhibition of CTLA-4 as a monotherapy or in combination with anti-PD1 prevents the growth of murine bla
Unravelling T cell exhaustion through co-inhibitory receptors and its transformative role in cancer immunotherapy.
Dual CTLA-4 and PD-1 checkpoint blockade using CS1002 and CS1003 (nofazinlimab) in patients with advanced solid tumors:
Combined anti-PD-1 and anti-CTLA-4 checkpoint blockade: Treatment of melanoma and immune mechanisms of action.
Bempegaldesleukin (BEMPEG; NKTR-214) efficacy as a single agent and in combination with checkpoint-inhibitor therapy in
NK- and T-cell subsets in malignant mesothelioma patients: Baseline pattern and changes in the context of anti-CTLA-4 th
Immune checkpoint inhibitors in advanced nasopharyngeal carcinoma: Beyond an era of chemoradiation?
Hematological toxicities in immune checkpoint inhibitors: A pharmacovigilance study from 2014 to 2019.
Dendritic Cell Derived-Extracellular Vesicles Engineered to Express Interleukin-12 and Anti-CTLA-4 on Their Surface for
Paradoxical Effect of Myosteatosis on the Immune Checkpoint Inhibitor Response in Metastatic Renal Cell Carcinoma.
Ileus in patients treated with immune checkpoint inhibitors: A retrospective, pharmacovigilance study using Food and Dru
Skin Reactions to Immune Checkpoint Inhibitors.
Immunotherapy in Lung Cancer: Are the Promises of Long-Term Benefit Finally Met?
Personalized Therapy of Small Cell Lung Cancer.
Immunotherapy in Lung Cancer.
Monoclonal Antibodies to CTLA-4 with Focus on Ipilimumab.
Immune Therapy for Sarcomas.
Inhibition of SRC family kinases facilitates anti-CTLA4 immunotherapy in head and neck squamous cell carcinoma.
Immune checkpoint inhibitors enhance cytotoxicity of cytokine-induced killer cells against human myeloid leukaemic blast
Immune-modulating properties of ionizing radiation: rationale for the treatment of cancer by combination radiotherapy an
Indoleamine 2,3-dioxygenase provides adaptive resistance to immune checkpoint inhibitors in hepatocellular carcinoma.
Immune checkpoint inhibitors reverse tolerogenic mechanisms induced by melanoma targeted radionuclide therapy.
The expression of MHC class II molecules on murine breast tumors delays T-cell exhaustion, expands the T-cell repertoire
The glucocorticoids prednisone and dexamethasone differentially modulate T cell function in response to anti-PD-1 and an
Enhanced anti-tumor efficacy of checkpoint inhibitors in combination with the histone deacetylase inhibitor Belinostat i
Occurrence of type 1 and type 2 diabetes in patients treated with immunotherapy (anti-PD-1 and/or anti-CTLA-4) for metas
Antisense targeting of CD47 enhances human cytotoxic T-cell activity and increases survival of mice bearing B16 melanoma
Disruption of CTLA-4 expression on peripheral blood CD8 + T cell enhances anti-tumor efficacy in bladder cancer.
Development of immunotherapy in bladder cancer: present and future on targeting PD(L)1 and CTLA-4 pathways.
CTLA-4 Blockade Suppresses Progression of Residual Tumors and Improves Survival After Insufficient Radiofrequency Ablati
Specific T-cell immune responses against colony-forming cells including leukemic progenitor cells of AML patients were i
Evaluation of the efficacy of immunotherapy for non-resectable mucosal melanoma.
Low dose novel PARP-PI3K inhibition via nanoformulation improves colorectal cancer immunoradiotherapy.
Impact of immune-related adverse event severity on overall survival in patients with advanced NSCLC receiving immune che
Prussian blue nanoparticle-based photothermal therapy combined with checkpoint inhibition for photothermal immunotherapy
Breaking immune evasion in breast cancer by targeting COX-2/PGE2 pathway.
Combination of immune checkpoint blockade in metastatic colorectal cancers with microsatellite instability: A new standa
Integrating CTLA-4/PD-1 blockade into cervical cancer management: Results of COMPASSION-16.
Phototherapy using immunologically modified carbon nanotubes to potentiate checkpoint blockade for metastatic breast can
Improved tumor accumulation and therapeutic efficacy of CTLA-4-blocking antibody using liposome-encapsulated antibody: I
Oncolytic herpes virus G47Δ works synergistically with CTLA-4 inhibition via dynamic intratumoral immune modulation.
Oncolytic vaccinia virus expressing non-secreted decoy-resistant IL-18 mutein elicits potent antitumor effects with enha
Optimal radiation dose to induce an abscopal effect by combining carbon-ion radiotherapy and anti-CTLA4 antibody.
CD103 blockade impair anti-CTLA-4 immunotherapy in oral cancer.
[Immune-related adverse events after immune checkpoints inhibitors in 2019: An update].
The impact of PD-L1 as a biomarker of cancer responses to combo anti-PD-1/CTLA-4.
Immune checkpoint inhibitors-induced systemic capillary leak syndrome: A report of two cases.
Immune checkpoints and cancer development: Therapeutic implications and future directions.
Clinical experience with CTLA-4 blockade for cancer immunotherapy: From the monospecific monoclonal antibody ipilimumab
Ophthalmic Immune-Related Adverse Events after Anti-CTLA-4 or PD-1 Therapy Recorded in the American Academy of Ophthalmo
In vitro-irradiated cancer vaccine enhances anti-tumor efficacy of radiotherapy and PD-L1 blockade in a syngeneic murine
Clinical presentation of immune checkpoint inhibitor-induced inflammatory arthritis differs by immunotherapy regimen.
Cancer immunotherapy with check point inhibitor can cause autoimmune adverse events due to loss of Treg homeostasis.
Tumor mutation burden in the prognosis and response of lung cancer patients to immune-checkpoint inhibition therapies.
Mixing it up: boosting responses with immunotherapy combinations.
Combination therapy: Future directions of immunotherapy in small cell lung cancer.
Anti-CTLA-4 and anti-PD-1 immunotherapies repress tumor progression in preclinical breast and colon model with independe
T-cell immunotherapy for melanoma.
Immunosuppressive Myeloid Cells' Blockade in the Glioma Microenvironment Enhances the Efficacy of Immune-Stimulator
Synergy of Immune Checkpoint Blockade with a Novel Synthetic Consensus DNA Vaccine Targeting TERT.
Synergistic effects of combined immunotherapy strategies in a model of multifocal hepatocellular carcinoma.
DNA-Based Delivery of Checkpoint Inhibitors in Muscle and Tumor Enables Long-Term Responses with Distinct Exposure.
Fc-optimized anti-CTLA-4 antibodies increase tumor-associated high endothelial venules and sensitize refractory tumors t
[Not Available].
4-1BB+ Tregs and inhibitory progenitor exhausted T cells confer resistance to anti-PD-L1 and anti-CTLA-4 combination the
ICOS Costimulation at the Tumor Site in Combination with CTLA-4 Blockade Therapy Elicits Strong Tumor Immunity.
[Not Available].
[Not Available].
[Not Available].
[First line treatment of non-oncogene-addicted metastatic non-small cell lung cancer].
Cationic Peptide Conjugation Enhances Intratumoral Retention and Antitumor Efficacy of Immune Checkpoint Blockade Antibo
A Folate Receptor β-Targeted TLR7 Agonist Significantly Augments Checkpoint Inhibitor Potencies by Reprogramming Tumor-A
Design, Synthesis, and T Cell Checkpoint Combination Potential Of First-In-Class DGKα/ζ Inhibitor BMS-986408.
Immunotherapy in Melanoma: Highlights for the General Practitioner.
Gut microbiota modulation of chemotherapy efficacy and toxicity.
Combining immune check-point blockade and cryoablation in an immunocompetent hormone sensitive murine model of prostate
Safety profiles of anti-CTLA-4 and anti-PD-1 antibodies alone and in combination.
TP53 Mutation as Potential Negative Predictor for Response of Anti-CTLA-4 Therapy in Metastatic Melanoma.
The microbial metabolite desaminotyrosine enhances T-cell priming and cancer immunotherapy with immune checkpoint inhibi
Tumour mutational burden as a biomarker in patients with mismatch repair deficient/microsatellite instability-high metas
Evolution and recurrence of gastrointestinal immune-related adverse events induced by immune checkpoint inhibitors.
Checkpoint inhibitors in chronic kidney failure and an organ transplant recipient.
Stereotactic radiosurgery and anti-PD-1 + CTLA-4 therapy, anti-PD-1 therapy, anti-CTLA-4 therapy, BRAF/MEK inhibitors, B
MEK inhibition may increase survival of NRAS-mutated melanoma patients treated with checkpoint blockade: Results of a re
Real-world efficacy of anti-PD-1 antibody or combined anti-PD-1 plus anti-CTLA-4 antibodies, with or without radiotherap
Associations between patient and disease characteristics and severe adverse events during immune checkpoint inhibitor tr
Neoadjuvant immunotherapy is reshaping cancer management across multiple tumour types: The future is now!
Second- and third-generation drugs for immuno-oncology treatment-The more the better?
Outcome of melanoma patients with elevated LDH treated with first-line targeted therapy or PD-1-based immune checkpoint
Seasonal patterns of toxicity in melanoma patients treated with combination anti-PD-1 and anti-CTLA-4 immunotherapy.
Improved clinical outcomes with low-dose anti-CTLA-4 (Nurulimab) plus anti-PD-1 (Prolgolimab) vs. anti-PD-1 monotherapy
Thyroid Immune-Related Adverse Events in Patients with Cancer Treated with anti-PD1/anti-CTLA4 Immune Checkpoint Inhibit
Age effects of distinct immune checkpoint blockade treatments in a mouse melanoma model.
MOVIE: a phase I, open-label, multicenter study to evaluate the safety and tolerability of metronomic vinorelbine combin
Neoadjuvant Therapies for Bladder Cancer in Cisplatin-ineligible Patients: What Options Do We Have?
Anti-PD-1 alone or in combination with anti-CTLA-4 for advanced melanoma patients with liver metastases.
CRISPR knock out CTLA-4 enhances the anti-tumor activity of cytotoxic T lymphocytes.
Unique Cytologic Features of Thyroiditis Caused by Immune Checkpoint Inhibitor Therapy for Malignant Melanoma.
Characterizing immune checkpoint inhibitor-related cutaneous adverse reactions: A comprehensive analysis of FDA adverse
Selective activation of pro-anti-CTLA-4 antibody maintains therapeutic efficacy and reduces immune-related adverse event
Combining Dual Checkpoint Immunotherapy with Ablative Radiation to All Sites of Oligometastatic Non-Small Cell Lung Canc
Nivolumab plus ipilimumab combination therapy in cancer: Current evidence to date.
PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 Pat
Anti-vascular endothelial growth factor treatment potentiates immune checkpoint blockade through a BAFF- and IL-12-depen
Immune checkpoint blockade in melanoma: Advantages, shortcomings and emerging roles of the nanoparticles.
Cordycepin synergizes with CTLA-4 blockade to remodel the tumor microenvironment for enhanced cancer immunotherapy.
Unleashing the Power of immune Checkpoints: A new strategy for enhancing Treg cells depletion to boost antitumor immunit
Dermatologic infections in cancer patients treated with checkpoint inhibitors.
Oncolytic microgels with regulated antibody release augment tumor immunotherapy.
Anti-CTLA-4 antibody self-presented dendritic cell nanovesicles boost the immunotherapy of hepatocellular carcinoma afte
Analyzing the relationship between the efficacy of first-line immune checkpoint inhibitors and cumulative sun damage in
Enhancement of antitumor immunity by CTLA-4 antisense oligonucleotides with CpG motif in mice.
Blockade of CTLA-4 increases anti-tumor response inducing potential of dendritic cell vaccine.
Characterization of liver injury induced by cancer immunotherapy using immune checkpoint inhibitors.
Combined immunotherapy: CTLA-4 blockade potentiates anti-tumor response induced by transcutaneous immunization.
Immunologic effects of locoregional therapies for unresectable hepatocellular carcinoma.
A Commotion in the Skin: Developing Melanoma Immunotherapies.
Burden of grade 3 or 4 liver injury associated with immune checkpoint inhibitors.
The Emerging Role of Surgery for Patients With Advanced Melanoma Treated With Immunotherapy.
Immune checkpoint inhibitor-induced interstitial lung disease with and without CTLA-4 regimen in non-small cell lung can
Pathological findings of immunotherapy-induced nephrotoxicity in a humanized immune system mouse model.
A multicenter, open-label phase Ib/II study of cadonilimab (anti PD-1 and CTLA-4 bispecific antibody) monotherapy in pre
Immune checkpoint blockade in small cell lung cancer.
Antitumor Immunity Augmented by Combining Radiofrequency Ablation with Anti-CTLA-4 Therapy in a Subcutaneous Murine Hepa
Systemic anti-CTLA-4 and intravesical Bacille-Calmette-Guerin therapy in non-muscle invasive bladder cancer: Is there a
Energy status dictates PD-L1 protein abundance and anti-tumor immunity to enable checkpoint blockade.
Intracranial administration of anti-PD-1 and anti-CTLA-4 immune checkpoint-blocking monoclonal antibodies in patients wi
MiR-138 exerts anti-glioma efficacy by targeting immune checkpoints.
Fc-enhanced anti-CTLA-4, anti-PD-1, doxorubicin, and ultrasound-mediated blood-brain barrier opening: A novel combinator
First-line PD-1 +/- CTLA-4 blockade in patients with deficient mismatch repair and/or microsatellite instability-high me
Immune Checkpoint Inhibitor-related New-onset Thyroid Dysfunction: A Retrospective Analysis Using the US FDA Adverse Eve
Mechanisms of immune-related adverse events during the treatment of cancer with immune checkpoint inhibitors.
Blocking CTLA-4 promotes pressure overload-induced heart failure via activating Th17 cells.
Novel therapeutic agents in the management of brain metastases.
Side-effects of checkpoint inhibitor-based combination therapy.
DZ-2384 has a superior preclinical profile to taxanes for the treatment of triple-negative breast cancer and is synergis
Cancer Stem Cell Vaccination With PD-L1 and CTLA-4 Blockades Enhances the Eradication of Melanoma Stem Cells in a Mouse
Tumor Regression and Cure Depends on Sustained Th1 Responses.
Sarcoidosis Following Anti-PD-1 and Anti-CTLA-4 Therapy for Metastatic Melanoma.
Checkpoint inhibitors and gastrointestinal immune-related adverse events.
Immune Checkpoint Inhibitor-induced Bilateral Vestibulopathy.
Development of Bell's Palsy After Treatment With Ipilimumab and Nivolumab for Metastatic Melanoma: A Case Report.
Type 1 diabetes induced by immune checkpoint inhibitors.
Rapid and Complete Response to Combination Anti-CTLA-4 and Anti-PD-1 Checkpoint Inhibitor Therapy in a Patient With Stag
Conception and viable twin pregnancy in a patient with metastatic melanoma while treated with CTLA-4 and PD-1 checkpoint
Generalized morphoea in the setting of combined immune checkpoint inhibitor therapy for metastatic melanoma: A case repo
Safety of immune checkpoint inhibitors in Chinese patients with melanoma.
Immune Checkpoint Inhibitors-Related Cardiotoxicity.
Immune-related adverse events in cancer patients treated with immune checkpoint inhibitors: A single-center experience.
Programmed cell death-1 pathway inhibitors in genitourinary malignancies: specific side-effects and their management.
What Is on the Horizon for Novel Immunotherapies in Lung Cancer?
Inhibitors of Cytotoxic T Lymphocyte Antigen 4 and Programmed Death 1/Programmed Death 1 Ligand for Metastatic Melanoma,
Reprogramming Intrahepatic Cholangiocarcinoma Immune Microenvironment by Chemotherapy and CTLA-4 Blockade Enhances Anti-
Coordinated macrophage and T cell interactions mediate response to checkpoint blockade in colorectal cancer.
High Antigenicity for Treg Cells Confers Resistance to PD-1 Blockade Therapy via High PD-1 Expression in Treg Cells.
Melanoma therapy: Check the checkpoints.
LAG-3 : recent developments in combinational therapies in cancer.
Immune checkpoint molecules in acute myeloid leukaemia: managing the double-edged sword.
Rechallenge with checkpoint inhibitors in metastatic melanoma.
Activated CTLA-4-independent immunosuppression of Treg cells disturbs CTLA-4 blockade-mediated antitumor immunity.
A combination of lymphatic drug delivery of anti-CTLA-4 antibody and local radiotherapy for solid-tumor treatment.
Fc Effector Function of Immune Checkpoint Blocking Antibodies in Oncology.
The cyclin-dependent kinase inhibitor AT7519 is a human RORγt agonist.
Management of side effects of immune checkpoint blockade by anti-CTLA-4 and anti-PD-1 antibodies in metastatic melanoma.
Application of a patient-centered reverse translational systems-based approach to understand mechanisms of an adverse dr
Pan-Cancer Landscape of B- and T-Lymphocyte Attenuator: Implications for Potential Immunotherapy Combinations.
Discrepant CD3+ TILs in PD-L1-Negative NSCLC: Favorable Outcome in an Elderly Patient Treated With Nivolumab, Ipilimumab
Longitudinal monitoring of tumor response to immune checkpoint inhibitors using noninvasive diffuse reflectance spectros
[Advances in Immunotherapy of Malignant Melanoma].
The Era of Checkpoint Blockade in Lung Cancer: Taking the Brakes Off the Immune System.
[Immunotherapy of Renal Cell Carcinoma].
Recurrent Pneumonitis in Patients with Melanoma Treated with Immune Checkpoint Inhibitors.
Clinical heterogeneity of hypophysitis secondary to PD-1/PD-L1 blockade: insights from four cases.
Management of Adverse Events Following Treatment With Anti-Programmed Death-1 Agents.
New Clinical Approaches and Emerging Evidence on Immune-Checkpoint Inhibitors as Anti-Cancer Therapeutics: CTLA-4 and PD
Incidence of Thyroid Function Test Abnormalities in Patients Receiving Immune-Checkpoint Inhibitors for Cancer Treatment
[Management of immune-related adverse events during treatment with immune checkpoint inhibitors].
Checkpoint inhibitors in squamous cell carcinoma of the head and neck: History and new perspectives.
Metastatic lesion of a choroidal melanoma located in the head of pancreas.
Non-small cell lung cancer with MET exon 14 skipping alteration responding to immunotherapy: a case report.
Pulmonary metastasectomy in the era of targeted therapy and immunotherapy.
Emerging insights into STK11, KEAP1 and KRAS mutations: implications for immunotherapy in patients with advanced non-sma
First case report of immune checkpoint inhibitor-related pneumonitis triggered by bispecific antibody (anti-PD-L1 and an
Emerging Immunotargets and Immunotherapies in Prostate Cancer.
Combining Radiotherapy with Immunocheckpoint Inhibitors or CAR-T in Renal Cell Carcinoma.
CTLA-4: As an Immunosuppressive Immune Checkpoint in Breast Cancer.
Combined KIT and CTLA-4 Blockade in Patients with Refractory GIST and Other Advanced Sarcomas: A Phase Ib Study of Dasat
Anti-CTLA-4 Immunotherapy Does Not Deplete FOXP3+ Regulatory T Cells (Tregs) in Human Cancers.
Immunotherapy of Melanoma: Facts and Hopes.
In Situ Vaccination after Accelerated Hypofractionated Radiation and Surgery in a Mesothelioma Mouse Model.
Circulating Cytokines Predict Immune-Related Toxicity in Melanoma Patients Receiving Anti-PD-1-Based Immunotherapy.
Probody Therapeutics: An Emerging Class of Therapies Designed to Enhance On-Target Effects with Reduced Off-Tumor Toxici
Targeting PD-1 or PD-L1 in Metastatic Kidney Cancer: Combination Therapy in the First-Line Setting.
Immune Checkpoint Inhibitor-induced Reinvigoration of Tumor-infiltrating CD8+ T Cells is Determined by Their Differentia
Clinical and Molecular Predictors of Response to Immune Checkpoint Inhibitors in Patients with Advanced Esophagogastric
A Phase II Basket Trial of Dual Anti-CTLA-4 and Anti-PD-1 Blockade in Rare Tumors SWOG S1609: Vulvar Cancers.
Predictive Immune-Checkpoint Blockade Classifiers Identify Tumors Responding to Inhibition of PD-1 and/or CTLA-4.
A Population-Level Real-World Analysis and Single-Center Validation of Melanoma Brain Metastasis Epidemiology following
Anti-KIT Monoclonal Antibody Treatment Enhances the Antitumor Activity of Immune Checkpoint Inhibitors by Reversing Tumo
SWOG/NCI Phase II Dual Anti-CTLA-4/PD-1 Blockade in Rare Tumors: Nonepithelial Ovarian Cancer.
Macrophage-Derived CXCL9 and CXCL10 Are Required for Antitumor Immune Responses Following Immune Checkpoint Blockade.
The Exportin-1 Inhibitor Selinexor Exerts Superior Antitumor Activity when Combined with T-Cell Checkpoint Inhibitors.
Checkpoint Inhibitors Boost Power of Antibody-Drug Conjugate.
Novel Chimeric CTLA-4 B-cell Epitope Peptide Vaccines Demonstrate Effective Antitumor Immunity with/without PD1/PDL1 Blo
Microneedle-mediated Intratumoral Delivery of Anti-CTLA-4 Promotes cDC1-dependent Eradication of Oral Squamous Cell Carc
A Single-Arm Phase 2 Trial of Doxorubicin Plus Zalifrelimab (Anti-CTLA-4 Antibody) and Balstilimab (Anti-PD-1 Antibody)
Suppression of Metastases Using a New Lymphocyte Checkpoint Target for Cancer Immunotherapy.
PD-1, CTLA-4 Point to Drug Response.
Coxsackievirus A21 Synergizes with Checkpoint Inhibitors.
Vaccines Combined with Immune Checkpoint Antibodies Promote Cytotoxic T-cell Activity and Tumor Eradication.
Interferon-γ Production by Peripheral Lymphocytes Predicts Survival of Tumor-Bearing Mice Receiving Dual PD-1/CTLA-4 Blo
A2AR Antagonism with CPI-444 Induces Antitumor Responses and Augments Efficacy to Anti-PD-(L)1 and Anti-CTLA-4 in Precli
Tumor-Specific Inhibition of In Situ Vaccination by Distant Untreated Tumor Sites.
Combining Local Immunotoxins Targeting Mesothelin with CTLA-4 Blockade Synergistically Eradicates Murine Cancer by Promo
Antibody-Mediated Phosphatidylserine Blockade Enhances the Antitumor Responses to CTLA-4 and PD-1 Antibodies in Melanoma
Glioblastoma Eradication Following Immune Checkpoint Blockade in an Orthotopic, Immunocompetent Model.
Entinostat Converts Immune-Resistant Breast and Pancreatic Cancers into Checkpoint-Responsive Tumors by Reprogramming Tu
An Artificial Antigen-Presenting Cell Delivering 11 Immune Molecules Expands Tumor Antigen-Specific CTLs in Ex Vivo and
Stromal Fibroblasts Mediate Anti-PD-1 Resistance via MMP-9 and Dictate TGFβ Inhibitor Sequencing in Melanoma.
Autoantibody Development under Treatment with Immune-Checkpoint Inhibitors.
Anti-PD-1-Induced Pneumonitis Is Associated with Persistent Imaging Abnormalities in Melanoma Patients.
Anti-CTLA-4 Activates Intratumoral NK Cells and Combined with IL15/IL15Rα Complexes Enhances Tumor Control.
Radiotherapy and CTLA-4 Blockade Shape the TCR Repertoire of Tumor-Infiltrating T Cells.
Dual PD-1 and CTLA-4 Checkpoint Blockade Promotes Antitumor Immune Responses through CD4+Foxp3- Cell-Mediated Modulation
Targeted Delivery of IL2 to the Tumor Stroma Potentiates the Action of Immune Checkpoint Inhibitors by Preferential Acti
Intermittent MEK Inhibition with GITR Costimulation Rescues T-cell Function for Increased Efficacy with CTLA-4 Blockade
Blockade of CTLA-4 and PD-1 Enhances Adoptive T-cell Therapy Efficacy in an ICOS-Mediated Manner.
Preclinical Characterization of Relatlimab, a Human LAG-3-Blocking Antibody, Alone or in Combination with Nivolumab.
IL2/Anti-IL2 Complex Combined with CTLA-4, But Not PD-1, Blockade Rescues Antitumor NK Cell Function by Regulatory T-cel
Myeloid Cells Orchestrate Systemic Immunosuppression, Impairing the Efficacy of Immunotherapy against HPV+ Cancers.
Inhibition of Tryptophan-Dioxygenase Activity Increases the Antitumor Efficacy of Immune Checkpoint Inhibitors.
Anti-CTLA4 Therapy Leads to Early Expansion of a Peripheral Th17 Population and Induction of Th1 Cytokines.
Nonredundant Immune Checkpoints Direct Therapeutic Resistance to Chemoimmunotherapy in Pancreatic Ductal Adenocarcinoma.
VISTA Targeting of T-cell Quiescence and Myeloid Suppression Overcomes Adaptive Resistance.
Reprogramming the Intrahepatic Cholangiocarcinoma Immune Microenvironment by Chemotherapy and CTLA-4 Blockade Enhances A
Removal of Interstitial Hyaluronan Facilitates Subcutaneous Administration and Lymphatic Delivery of Anti-CTLA4 and Impr
Immune Checkpoint Inhibition in Hepatocellular Carcinoma: Basics and Ongoing Clinical Trials.
Effects of Combination of Anti-CTLA-4 and Anti-PD-1 on Gastric Cancer Cells Proliferation, Apoptosis and Metastasis.
Systemic Therapy for Hepatocellular Carcinoma: 2017 Update.
Immuno-Oncology in Hepatocellular Carcinoma: 2017 Update.
Intratumoral DNA-based delivery of checkpoint-inhibiting antibodies and interleukin 12 triggers T cell infiltration and
Nanobody-based bispecific antibody engagers targeting CTLA-4 or PD-L1 for cancer immunotherapy.
Prophylactic TNF blockade uncouples efficacy and toxicity in dual CTLA-4 and PD-1 immunotherapy.
Robust prediction of response to immune checkpoint blockade therapy in metastatic melanoma.
Preoperative ipilimumab plus nivolumab in locoregionally advanced urothelial cancer: the NABUCCO trial.
Intratumoral follicular regulatory T cells curtail anti-PD-1 treatment efficacy.
Efficacy of CTLA-4 checkpoint therapy is dependent on IL-21 signaling to mediate cytotoxic reprogramming of PD-1+CD8+ T
CTLA-4 and PD-1 dual blockade induces SIV reactivation without control of rebound after antiretroviral therapy interrupt
Neoadjuvant PD-L1 plus CTLA-4 blockade in patients with cisplatin-ineligible operable high-risk urothelial carcinoma.
Radiotherapy induces responses of lung cancer to CTLA-4 blockade.
CTLA-4 blockade drives loss of Treg stability in glycolysis-low tumours.
Is earlier better for melanoma checkpoint blockade?
Single-cell transcriptomic analyses reveal distinct immune cell contributions to epithelial barrier dysfunction in check
Treatment- and immune-related adverse events of immune checkpoint inhibitors in advanced lung cancer.
Anti-CTLA-4 antibodies drive myeloid activation and reprogram the tumor microenvironment through FcγR engagement and typ
[Management of adverse events in immune oncology - Practical aspects of immune-related adverse events during immune onco
Cancer immunotherapy-associated hypophysitis.
[Immunooncology in Urologic Cancers: Current Status].
Five-Year Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma
Hypothyroidism in Cancer Patients on Immune Checkpoint Inhibitors with anti-PD1 Agents: Insights on Underlying Mechanism
Immune checkpoint blockade enhances chemophototherapy in a syngeneic pancreatic tumor model.
Anti-PD-1/anti-CTLA-4 efficacy in melanoma brain metastases depends on extracranial disease and augmentation of CD8+ T c
Bifidobacterium can mitigate intestinal immunopathology in the context of CTLA-4 blockade.
Differential control of human Treg and effector T cells in tumor immunity by Fc-engineered anti-CTLA-4 antibody.
Differential effects of PD-1 and CTLA-4 blockade on the melanoma-reactive CD8 T cell response.
Combining microenvironment normalization strategies to improve cancer immunotherapy
Thiopurine therapy enhances immune checkpoint inhibitor efficacy in low-mutational burden melanoma: A promising anticanc
TLR1/2 ligand enhances antitumor efficacy of CTLA-4 blockade by increasing intratumoral Treg depletion.
Generating tumor-selective conditionally active biologic anti-CTLA4 antibodies via protein-associated chemical switches.
pH-dependent dissociation from CTLA-4 in early endosomes improves both safety and antitumor activity of anti-CTLA-4 anti
Post-immunotherapy CTLA-4 Ig treatment improves antitumor efficacy.
Anti-CTLA-4 generates greater memory response than anti-PD-1 via TCF-1.
A small-sized protein binder specific for human PD-1 effectively suppresses the tumour growth in tumour mouse model.
LILRB4 expression in chronic myelomonocytic leukemia and myelodysplastic syndrome based on response to hypomethylating a
Ocular Adverse Events Induced by Immune Checkpoint Inhibitors: A Comprehensive Pharmacovigilance Analysis.
Immunological Characteristics of Colitis Associated with Anti-CTLA-4 Antibody Therapy.
[CTIA-4 blockade therapy; biology and clinical activity].
[Clinical Significance of Ipilimumab and the Combination Therapy as Immune Checkpoint Inhibitor].
Combination therapy of cytotoxic t-lymphocyte-associated antigen 4 (ctla-4) and programmed death 1 (pd 1) blocker, check
Combination Controversies: Checkpoint Inhibition Alone or in Combination for the Treatment of Melanoma?
Direct suppression of autoaggressive CD8+ T cells with CD80/86 blockade in CD8+ T cell-mediated polymyositis models of m
[Development of immune checkpoint inhibitor in colorectal cancer].
[Immune checkpoint (PD-1 and CTIA-4) signal inhibitors for gynecologic oncology; up to date].
[Efficacy and Management of Adverse Events of Ipilimumab Including Combination Therapy with Nivolumab].
[Endocrinopathies induced by immune checkpoint inhibitors].
[Immune Checkpoint Inhibitor Related Enterocolitis].
[Immune checkpoint antibodies increase survival in patients with metastatic melanoma].
Integrin signaling gene alterations and outcomes of cancer patients receiving immune checkpoint inhibitors.
[Immunotherapy with immune checkpoint inhibitor and skin toxicity].
[Progression of immunotherapy in gastric cancer].
[Understanding Tumor Immunity by Immune Genome Profiling of the Cancer Tissue].
Trends in the treatment of advanced hepatocellular carcinoma: immune checkpoint blockade immunotherapy and related combi
[The development status of the next-generation immune checkpoint inhibitors].
Clinical assessment of immune-related adverse events.
Multiple autoimmune side effects of immune checkpoint inhibitors in a patient with metastatic melanoma receiving pembrol
Sustained clinico-radiologic response to anti-cytotoxic T lymphocyte antigen 4 antibody therapy in metastatic myxoid lip
Current status of treatment with immune checkpoint inhibitors for gastrointestinal, hepatobiliary, and pancreatic cancer
Pharmacovigilance study on the reporting frequency of atrial fibrillation with immune checkpoint inhibitors: insights fr
High CTLA-4 transcriptomic expression correlates with high expression of other checkpoints and with immunotherapy outcom
A Single-Arm Multi-Center Phase II Clinical Trial of Cadonilimab (anti-PD-1/CTLA-4) in Combination with or without Conve
Advances in immunotherapy for colorectal cancer: overcoming resistance in mismatch repair-proficient tumors.
The MEK inhibitor selumetinib complements CTLA-4 blockade by reprogramming the tumor immune microenvironment.
Thrombocytopenia in patients with melanoma receiving immune checkpoint inhibitor therapy.
Inflammation-induced hypoparathyroidism triggered by combination immune checkpoint blockade for melanoma.
Metastatic uveal melanoma showing durable response to anti-CTLA-4 and anti-PD-1 combination therapy after experiencing p
Current landscape and future of dual anti-CTLA4 and PD-1/PD-L1 blockade immunotherapy in cancer; lessons learned from cl
Case series of cancer patients who developed cholecystitis related to immune checkpoint inhibitor treatment.
The CTLA-4 x OX40 bispecific antibody ATOR-1015 induces anti-tumor effects through tumor-directed immune activation.
A whole-blood RNA transcript-based gene signature is associated with the development of CTLA-4 blockade-related diarrhea
Non-invasive biomarkers derived from the extracellular matrix associate with response to immune checkpoint blockade (ant
Distinct predictive biomarker candidates for response to anti-CTLA-4 and anti-PD-1 immunotherapy in melanoma patients.
Tumor mutation burden and circulating tumor DNA in combined CTLA-4 and PD-1 antibody therapy in metastatic melanoma - re
Endocrine toxicity of immune checkpoint inhibitors: a real-world study leveraging US Food and Drug Administration advers
Immunogenicity of prostate cancer is augmented by BET bromodomain inhibition.
Recovery from secondary adrenal insufficiency in a patient with immune checkpoint inhibitor therapy induced hypophysitis
Efficacy of metformin in combination with immune checkpoint inhibitors (anti-PD-1/anti-CTLA-4) in metastatic malignant m
Immune checkpoint inhibitor-related acral vasculitis.
Rescue therapy for patients with anti-PD-1-refractory Merkel cell carcinoma: a multicenter, retrospective case series.
Immune microenvironment modulation unmasks therapeutic benefit of radiotherapy and checkpoint inhibition.
Emerging Strategies in Systemic Therapy for the Treatment of Melanoma.
TLR9 activation cooperates with T cell checkpoint blockade to regress poorly immunogenic melanoma.
Corticosteroids for Immune-Related Adverse Events and Checkpoint Inhibitor Efficacy: Analysis of Six Clinical Trials.
Endocrine Toxicity of Cancer Immunotherapy Targeting Immune Checkpoints.
Survival Outcomes After Metastasectomy in Melanoma Patients Categorized by Response to Checkpoint Blockade.
Ipilimumab: an investigational immunotherapy for glioblastoma.
Biliary disorders associated with immune checkpoint inhibitors: a pharmacovigilance analysis of the FDA adverse event re
Management of metastatic melanoma with combinations including PD-1 inhibitors.
Immune checkpoint inhibitors in gynecologic cancers with lessons learned from non-gynecologic cancers.
PD-1 checkpoint blockade alone or combined PD-1 and CTLA-4 blockade as immunotherapy for lung cancer?
Recent developments with immunotherapy for hepatocellular carcinoma.
Current knowledge of Ipilimumab and its use in treating non-small cell lung cancer.
Immunotherapy for small cell lung cancer: mechanisms of resistance.
The safety of talimogene laherparepvec for the treatment of advanced melanoma.
Hypophysitis related to immune checkpoint inhibitors: An intriguing adverse event with many faces.
Predictive biomarkers of response to immune checkpoint inhibitors in melanoma.
Immune checkpoint inhibitor-related gastrointestinal adverse events: a disproportionality analysis based on the FAERS da
Tremelimumab for the treatment of hepatocellular carcinoma.
Selecting immuno-oncology-based drug combinations - what should we be considering?
Novel immunotherapy in the treatment of advanced non-small cell lung cancer.
PI3Kγ inhibition drives M1 macrophage differentiation and synergizes with PD-L1 blockade to improve survival in poorly i
Therapy implications of the role of interleukin-2 in cancer.
Genomic and transcriptional changes in IFNγ pathway genes are putative biomarkers of response to ipilimumab immunotherap
Ex-vivo assessment of drug response on breast cancer primary tissue with preserved microenvironments.
Cadonilimab, a tetravalent PD-1/CTLA-4 bispecific antibody with trans-binding and enhanced target binding avidity.
Combined use of microwave ablation and cell immunotherapy induces nonspecific immunity of hepatocellular carcinoma model
Development of a mechanism of action-reflective, dual target cell-based reporter bioassay for a bispecific monoclonal an
A functional antibody cross-reactive to both human and murine cytotoxic T-lymphocyte-associated protein 4 via binding to
Immune checkpoint inhibitors for unresectable malignant pleural mesothelioma.
A B cell-derived gene expression signature associates with an immunologically active tumor microenvironment and response
PD-1 and LAG-3 blockade improve anti-tumor vaccine efficacy.
Tumor membrane-based vaccine immunotherapy in combination with anti-CTLA-4 antibody confers protection against immune ch
Next-generation CTLA-4 targeting molecules and combination therapy: promising strategies for improving cancer immunother
Reprogramming the immunosuppressive tumor microenvironment results in successful clearance of tumors resistant to radiat
CD40 agonism improves anti-tumor T cell priming induced by the combination of radiation therapy plus CTLA4 inhibition an
Predicting the response to CTLA-4 blockade by longitudinal noninvasive monitoring of CD8 T cells.
Myeloid-targeting immunotherapies overcome inhibitory barriers in immune-evasive neuroblastoma.
An Oncolytic Adenovirus Targeting Transforming Growth Factor β Inhibits Protumorigenic Signals and Produces Immune Activ
Radiotherapy and immunology.
Distinct Cytokine Signatures in Thyroiditis Induced by PD-1 or CTLA-4 Blockade: Insights from a New Mouse Model.
Clinical outcomes of melanoma brain metastases treated with stereotactic radiosurgery and anti-PD-1 therapy, anti-CTLA-4
Short-term CTLA-4 blockade directly followed by PD-1 blockade in advanced melanoma patients: a single-center experience.
Thyroid Toxicity Following Immune Checkpoint Inhibitor Treatment in Advanced Cancer.
Immune checkpoint inhibitors in advanced renal cell carcinoma: experience to date and future directions.
Safety of resuming anti-PD-1 in patients with immune-related adverse events (irAEs) during combined anti-CTLA-4 and anti
T cells isolated from patients with checkpoint inhibitor-resistant melanoma are functional and can mediate tumor regress
Neoadjuvant immune checkpoint inhibitors for patients with resectable stage III/IV melanoma: a nationwide real-life stud
Checkpoint Inhibitor Colitis Shows Drug-Specific Differences in Immune Cell Reaction That Overlap With Inflammatory Bowe
Immune checkpoint inhibitor-based combinations: is dose escalation mandatory for phase I trials?
Colon Immune-Related Adverse Events: Anti-CTLA-4 and Anti-PD-1 Blockade Induce Distinct Immunopathological Entities.
Immune checkpoint inhibition in ovarian cancer.
Differential shaping of T cell responses elicited by heterologous ChAd68/self-amplifying mRNA SIV vaccine in macaques in
T cell checkpoint regulators in the heart.
Human endogenous retrovirus-H long terminal repeat-associating 2: an emerging immune checkpoint for cancer immunotherapy
Immune-related adverse events in various organs caused by immune checkpoint inhibitors.
Efficacy and safety data for checkpoint inhibitors in advanced melanoma under real-life conditions: A monocentric study
New insight in endocrine-related adverse events associated to immune checkpoint blockade.
[Dermatologic toxicities of immune checkpoint inhibitors].
Improving cancer immunotherapy via co-delivering checkpoint blockade and thrombospondin-1 downregulator.
Subcutaneous inoculation position affects the immune environment in CT26 carcinomas.
Combination therapy with immune checkpoint inhibitors in colorectal cancer: Challenges, resistance mechanisms, and the r
Reinstating immunogenicity using bispecific anti-checkpoint/agent inhibitors.
Manipulation of tumor microenvironment by induction of immunogenic cell death and immune check point inhibitors for enha
[Autoimmune hypophysitis associated with new anti-cancer immunotherapies].
Immune checkpoint inhibitors win the 2018 Nobel Prize.
Cross-Disease myeloid remodeling along the GMP-TAM axis predicts immunotherapy response in glioma.
[What is the place of the combinations for immunotherapy with chemotherapy or with other immune checkpoint inhibitors?].
[Immune checkpoints inhibitors: Recent data from ASCO's meeting 2017 and perspectives].
[Checkpoint inhibitors-induced hypophysitis].
[Rheumatic immune adverse events related to immune checkpoint inhibitors-(IrAEs related to ICI)].
[Current advances in immunotherapy in ovarian cancer].
PD-1/PD-L1 checkpoint blockades in non-small cell lung cancer: New development and challenges.
Immunotherapy for hepatocellular carcinoma.
[Brain tumor immunotherapy: Illusion or hope?].
Dual blockade of PD-1 and CTLA-4 generates long-lasting immunity against irradiated glioblastoma.
Immune checkpoint Ab enhances the antigen-specific anti-tumor effects by modulating both dendritic cells and regulatory
Multiomic profiling of checkpoint inhibitor-treated melanoma: Identifying predictors of response and resistance, and mar
Treg-mediated acquired resistance to immune checkpoint inhibitors.
Carbon ion irradiation plus CTLA4 blockade elicits therapeutic immune responses in a murine tumor model.
Anti-PD-1/L1 lead-in before MAPK inhibitor combination maximizes antitumor immunity and efficacy.
Prior anti-CTLA-4 therapy impacts molecular characteristics associated with anti-PD-1 response in advanced melanoma.
Distinct Immune Cell Populations Define Response to Anti-PD-1 Monotherapy and Anti-PD-1/Anti-CTLA-4 Combined Therapy.
Overcoming tyrosine kinase inhibitor resistance in lung cancer brain metastasis with CTLA4 blockade.
Macrophage Polarization Contributes to Glioblastoma Eradication by Combination Immunovirotherapy and Immune Checkpoint B
Bringing immunotherapy to clinical practice in dMMR/MSI-high colon cancer.
Combination anti-PD-1 and anti-CTLA-4 therapy generates waves of clonal responses that include progenitor-exhausted CD8+
Pulmonary Toxicities from Checkpoint Immunotherapy for Malignancy.
Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer.
Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade.
The Histone Methyltransferase Ezh2 Controls Mechanisms of Adaptive Resistance to Tumor Immunotherapy.
Distinct CD8+ T cell dynamics associate with response to neoadjuvant cancer immunotherapies.
Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy.
Checkpoint inhibitors (CPI) and autoimmune chronic inflammatory diseases (ACIDs): tolerance and loss of tolerance in the
Anti-drug antibodies to LMB-100 are enhanced by mAbs targeting OX40 and CTLA4 but not by mAbs targeting PD1 or PDL-1.
A Phase III Study of Durvalumab (MEDI4736) With or Without Tremelimumab for Previously Treated Patients With Advanced NS
Itaconate transporter SLC13A3 confers immunotherapy resistance via alkylation-mediated stabilization of PD-L1.
Regimen Selection for Chemoimmunotherapy in Nonsquamous Non-Small Cell Lung Cancer with Low PD-L1 Expression: A Multicen
Retrospective study of the incidence of sarcoidosis-like reaction in patients treated with immunotherapy.
Immune signatures predicting responses to immunomodulatory antibody therapy.
RANK/RANKL signaling inhibition may improve the effectiveness of checkpoint blockade in cancer treatment.
Combined immune checkpoint blockade (anti-PD-1/anti-CTLA-4): Evaluation and management of adverse drug reactions.
Immunotherapy of colorectal cancer: Challenges for therapeutic efficacy.
Indoleamine 2,3-dioxygenase (IDO) inhibitors and cancer immunotherapy.
RIG-I activating immunostimulatory RNA boosts the efficacy of anticancer vaccines and synergizes with immune checkpoint
Immune Checkpoint Inhibitors and Cardiac Toxicity: An Emerging Issue.
Long-lasting Complete Remission Following Immunotherapy With Anti-PD1 Plus Anti-CTLA4 in a Polymetastatic Patient With N
Tumor Stroma Infiltrating T Cells Predict the Efficacy of Anti-CTLA-4 Antibody in NSCLC.
The role of nivolumab in melanoma.
Low-dose Radiation Improves Tumor Immune Microenvironment, Enhancing the Effects of Anti-CTLA-4 Therapy.
Phase III study of nivolumab alone or combined with ipilimumab as immunotherapy versus standard of care in resectable he
Ipilimumab after progression on anti-PD-1 treatment in advanced melanoma.
Clinical and economic outcomes associated with treatment sequences in patients with BRAF-mutant advanced melanoma.
RaPiDS (GOG-3028): randomized Phase II study of balstilimab alone or in combination with zalifrelimab in cervical cancer
Sequential treatment approaches in the management of BRAF wild-type advanced melanoma: a cost-effectiveness analysis.
Volume increase of spleen in melanoma patients undergoing immune checkpoint blockade.
Oncolytic herpes simplex virus immunovirotherapy in combination with immune checkpoint blockade to treat glioblastoma.
Depleting tumor-associated Tregs via nanoparticle-mediated hyperthermia to enhance anti-CTLA-4 immunotherapy.
Curing tumor-bearing mice by shifting a Th2 to a Th1 anti-tumor response.
Perioperative Immune Checkpoint Blockade for Muscle-Invasive and Metastatic Bladder Cancer.
The emerging role of immune checkpoint inhibition in malignant lymphoma.
Checkpoint Inhibitors.
TIGIT and CD96: new checkpoint receptor targets for cancer immunotherapy.
Prognostic effect of coexisting TP53 and ZFHX3 mutations in non-small cell lung cancer patients treated with immune chec
Prodrugs of paclitaxel improve in situ photo-vaccination.
Anti-CTLA-4 synergizes with dendritic cell-targeted vaccine to promote IL-3-dependent CD4+ effector T cell infiltration
Combination LIGHT overexpression and checkpoint blockade disrupts the tumor immune environment impacting colorectal live
BET inhibition sensitizes innate checkpoint inhibitor resistant melanoma to anti-CTLA-4 treatment.
Antibody-mediated neutralization of soluble MIC significantly enhances CTLA4 blockade therapy.
Resident Kupffer cells and neutrophils drive liver toxicity in cancer immunotherapy.
Regulatory T cell control of systemic immunity and immunotherapy response in liver metastasis.
Combined antiangiogenic and anti–PD-L1 therapy stimulates tumor immunity through HEV formation
Dual targeting of CTLA-4 and CD47 on Treg cells promotes immunity against solid tumors.
Addition of interleukin-2 overcomes resistance to neoadjuvant CTLA4 and PD1 blockade in ex vivo patient tumors.
MHC proteins confer differential sensitivity to CTLA-4 and PD-1 blockade in untreated metastatic melanoma.
Case of anti-Zic4 antibody-mediated cerebellar toxicity induced by dual checkpoint inhibition in head and neck squamous
Soluble CTLA-4 mutants ameliorate immune-related adverse events but preserve efficacy of CTLA-4- and PD-1-targeted immun
Autoimmune complications of immunotherapy: pathophysiology and management.
Intratumoral expression of IL-7 and IL-12 using an oncolytic virus increases systemic sensitivity to immune checkpoint b
Cardiotoxicity of immune checkpoint inhibitors.
Efficacy of immune checkpoint inhibitors for in-transit melanoma.
Combining BRAF inhibition with oncolytic herpes simplex virus enhances the immune-mediated antitumor therapy of BRAF-mut
Pickering emulsions with ethiodized oil and nanoparticles for slow release of intratumoral anti-CTLA4 immune checkpoint
Survival after checkpoint inhibitors for metastatic acral, mucosal and uveal melanoma.
Blood-based kinase activity profiling: a potential predictor of response to immune checkpoint inhibition in metastatic c
Combined CTLA-4 and PD-L1 blockade in patients with chemotherapy-naïve metastatic castration-resistant prostate cancer i
Nomogram to predict the outcomes of patients with microsatellite instability-high metastatic colorectal cancer receiving
Chemoradiation triggers antitumor Th1 and tissue resident memory-polarized immune responses to improve immune checkpoint
In situ vaccination at a peripheral tumor site augments response against melanoma brain metastases.
Pre-existing immune status associated with response to combination of sipuleucel-T and ipilimumab in patients with metas
Modeling resistance of colorectal peritoneal metastases to immune checkpoint blockade in humanized mice.
Releasing the brakes of tumor immunity with anti-PD-L1 and pushing its accelerator with L19-IL2 cures poorly immunogenic
OncoVEXmGM-CSFexpands tumor antigen-specific CD8+ T-cell response in preclinical models.
Combining CTLA-4 and angiopoietin-2 blockade in patients with advanced melanoma: a phase I trial.
Defects in the necroptosis machinery are a cancer resistance mechanism to checkpoint inhibitor immunotherapy.
Oncolytic virus expressing PD-1 inhibitors activates a collaborative intratumoral immune response to control tumor and s
Differential requirements for CD4+ T cells in the efficacy of the anti-PD-1+LAG-3 and anti-PD-1+CTLA-4 combinations in m
Efficacy and predictive biomarkers of immunotherapy in Epstein-Barr virus-associated gastric cancer.
Combining toll-like receptor agonists with immune checkpoint blockade affects antitumor vaccine efficacy.
Phase II basket trial of dual anti-CTLA-4 and anti-PD-1 blockade in rare tumors (DART) SWOG S1609: the desmoid tumors.
Constitutive reduction in the checkpoint inhibitor, CTLA-4, does not accelerate SLE in NZM 2328 mice.
TG6050, an oncolytic vaccinia virus encoding interleukin-12 and anti-CTLA-4 antibody, favors tumor regression via profou
XTX101, a tumor-activated, Fc-enhanced anti-CTLA-4 monoclonal antibody, demonstrates tumor-growth inhibition and tumor-s
Targeted inhibition of Aurora kinase A promotes immune checkpoint inhibition efficacy in human papillomavirus-driven can
Identification of anti-TIM-3 based checkpoint inhibitor combinations with activity in immunotherapy refractory melanoma
Local and distant response to intratumoral immunotherapy assessed by immunoPET in mice.
[Immune checkpoint inhibitors and allogeneic hematopoietic stem cell transplantation].
Impact of tumor localization on antitumor immunity with conditionally activated CTLA-4 blockade.
ROSE12, a novel anti-CTLA-4 FcγRs binding-enhanced antibody activated by extracellular adenosine triphosphate, shows tum
Targeting MARCO in combination with anti-CTLA-4 leads to enhanced melanoma regression and immune cell infiltration via m
Immune Toxicity with Checkpoint Inhibition for Metastatic Melanoma: Case Series and Clinical Management.
Neutralization of Tumor Acidity Improves Antitumor Responses to Immunotherapy.
Synthetic DNA-Encoded Monoclonal Antibody Delivery of Anti-CTLA-4 Antibodies Induces Tumor Shrinkage In Vivo.
PolyI:C and CpG Synergize with Anti-ErbB2 mAb for Treatment of Breast Tumors Resistant to Immune Checkpoint Inhibitors.
In Situ Tumor Vaccination by Combining Local Radiation and Tumor-Specific Antibody or Immunocytokine Treatments.
CD27 Agonism Plus PD-1 Blockade Recapitulates CD4+ T-cell Help in Therapeutic Anticancer Vaccination.
Immunostimulatory Monoclonal Antibodies and Immunomodulation: Harvesting the Crop.
CTLA-4 Limits Anti-CD20-Mediated Tumor Regression.
A Novel Murine GITR Ligand Fusion Protein Induces Antitumor Activity as a Monotherapy That Is Further Enhanced in Combin
Clinical characteristics of gastrointestinal immune-related adverse events of immune checkpoint inhibitors and their ass
[Protective effect and mechanism of Lactobacillus rhamnosus on immune checkpoint inhibitors related colitis in mice].
Colonic Perforation After Treatment With Nivolumab in Esophageal Cancer: A Case Report.
Immunotherapy for esophageal cancer: Where are we now and where can we go.
[Immunocheckpoint inhibition in head and neck squamous cell carcinoma: the current status and progress].
[Roles of Programmed Cell Death-1/Programmed Cell Death-ligand 1 and Cytotoxic T-lymphocyte-associated Protein 4 Signali
Combined PD-1 and CTLA-4 Blockade Increases the Risks of Multiple Pituitary Hormone Deficiency and Isolated Adrenocortic
Control of Memory Phenotype T Lymphocyte Homeostasis: Role of Costimulation.
Bispecific anti-PD-1/CTLA-4 antibody for advanced solid tumors.
Skin toxicity associated with immune checkpoint inhibitors based on the FDA adverse event reporting system 2011 - 2023 d
Immunotherapy of head and neck squamous cell carcinoma (HNSCC). Immune checkpoint blockade.
Immunotherapy combinations and chemotherapy sparing schemes in first line non-small cell lung cancer.
[Immune checkpoint‑targeted cancer immunotherapies].
Immune Checkpoint Inhibitor-Induced Upper Gastrointestinal Tract Inflammation Shows Morphologic Similarities to, but Is
Update on immunotherapy for renal cancer.
Histopathologic Characterization of Myocarditis Associated With Immune Checkpoint Inhibitor Therapy.
Role of Immunotherapy in the Management of Locally Advanced and Recurrent/Metastatic Cervical Cancer.
Safety and Efficacy of Checkpoint Inhibition in Patients With Melanoma and Preexisting Autoimmune Disease : A Cohort Stu
AdAPT-001, an oncolytic adenovirus armed with a TGF-β trap, overcomes in vivo resistance to PD-L1-immunotherapy.
The clinical added value of the addition of anti-CTL-4 to anti-PD-1 alone is questionable and clearly increasing toxicit
Pneumatosis intestinalis in cancer patients who received immune checkpoint inhibitors.
Docetaxel treatment together with CTLA-4 knockdown enhances reduction of cell viability and amplifies apoptosis stimulat
Combining forces: the promise and peril of synergistic immune checkpoint blockade and targeted therapy in metastatic mel
Immune checkpoint inhibitors and radiosurgery for newly diagnosed melanoma brain metastases.
The combination of stereotactic radiosurgery with immune checkpoint inhibition or targeted therapy in melanoma patients
Neuroimmunological adverse events associated with immune checkpoint inhibitor: a retrospective, pharmacovigilance study
Radiation necrosis with stereotactic radiosurgery combined with CTLA-4 blockade and PD-1 inhibition for treatment of int
Thyroid disorders induced by checkpoint inhibitors.
Management of V600E and V600K BRAF-Mutant Melanoma.
[18F]FDG-PET/CT Imaging for Response Characterisation of Experimental Melanomas to Anti-PD-L1/Anti-CTLA-4 Immunotherapy.
Immunotherapy for the Treatment of Uveal Melanoma: Current Status and Emerging Therapies.
Immunotherapy in Small Cell Lung Cancer Treatment: a Promising Headway for Future Perspective.
Endocrine, Sexual Function, and Infertility Side Effects of Immune Checkpoint Inhibitor Therapy for Genitourinary Cancer
Immune checkpoint inhibitor-associated new-onset hypophysitis: a retrospective analysis using the FAERS.
Enlighting the Shadow for Advanced Hepatocellular Carcinoma: Immunotherapy with Immune Checkpoint Inhibitors.
The Role of BRAF-Targeted Therapy for Advanced Melanoma in the Immunotherapy Era.
Construction of Genetically Modified Lactococcus lactis Producing Anti-human-CTLA-4 Single-Chain Fragment Variable.
Dermatologic Reactions to Immune Checkpoint Inhibitors : Skin Toxicities and Immunotherapy.
Combinatorial Therapies in Melanoma: MAPK Inhibitors and Beyond.
Metastatic Melanoma: Recent Therapeutic Progress and Future Perspectives.
Immune checkpoint inhibitor-associated pituitary adverse events: an observational, retrospective, disproportionality stu
Adverse Event Profiles of Anti-CTLA-4 and Anti-PD-1 Monoclonal Antibodies Alone or in Combination: Analysis of Spontaneo
Iparomlimab and Tuvonralimab: First Approval.
Anti-CTLA-4 antibody-functionalized dendritic cell-derived exosomes targeting tumor-draining lymph nodes for effective i
A phase II basket trial of dual anti-CTLA-4 and anti-PD-1 blockade in rare tumors (DART) SWOG S1609: durable responses a
Safety of combining thoracic radiation therapy with concurrent versus sequential immune checkpoint inhibition.
Oncolytic Newcastle disease virus expressing a checkpoint inhibitor as a radioenhancing agent for murine melanoma.
Evaluating Toxicity and Interaction Outcomes of Systemic Therapy and Stereotactic Ablative Radiation Therapy for Oligome
Impact of body composition on outcomes from anti-PD1 +/- anti-CTLA-4 treatment in melanoma.
DNA exonuclease Trex1 regulates radiotherapy-induced tumour immunogenicity
Radiobiology of stereotactic ablative radiotherapy (SABR): perspectives of clinical oncologists
Lung cancer immunotherapy: progress, pitfalls, and promises
Immunotherapy Plus Cryotherapy: Potential Augmented Abscopal Effect for Advanced Cancers
Front-Line ICI-Based Combination Therapy Post-TKI Resistance May Improve Survival in NSCLC Patients With EGFR Mutation
The Role of Immunotherapy to Overcome Resistance in Viral-Associated Head and Neck Cancer.
Table_1_FOLFOXIRI/Bevacizumab Plus Nivolumab as First-Line Treatment in Metastatic Colorectal Cancer RAS/BRAF Mutated: S
Prognostic and predictive value of YTHDF1 and YTHDF2 and their correlation with tumor-infiltrating immune cells in non-s
Metabolic barriers in non-small cell lung cancer with LKB1 and/or KEAP1 mutations for immunotherapeutic strategies.
An oral cancer vaccine using Bifidobacterium vector augments combination of anti-PD-1 and anti-CTLA-4 antibodies in mous
Association of PD-L1 positivity with Epstein Barr virus infection and microsatellite instability in gastric carcinomas w
Spatial transcriptomics reveals tumor microenvironment heterogeneity in EBV positive diffuse large B cell lymphoma
Prolonged response to dual immune checkpoint blockade in patients with advanced solid tumors: a case series.
Immune checkpoint blockade in triple negative breast cancer influenced by B cells through myeloid-derived suppressor cel
Immunologic correlates in a CIC::DUX4 fusion-positive sarcoma responsive to dual immune checkpoint blockade.
COX-2 expression positively correlates with PD-L1 expression in human melanoma cells
Immunotherapy for glioblastoma: the promise of combination strategies.
Aplastic anemia secondary to nivolumab and ipilimumab in a patient with metastatic melanoma: a case report.
The Dual Blockade of the TIGIT and PD-1/PD-L1 Pathway as a New Hope for Ovarian Cancer Patients
Clinical Outcomes in Fibrolamellar Hepatocellular Carcinoma Treated with Immune Checkpoint Inhibitors
Combination Immunotherapy in Prostate Cancer.
Merkel Cell Carcinoma-Update on Diagnosis, Management and Future Perspectives.
Immunotherapy for Glioblastoma: A Focus on PD-1/PD-L1 Inhibitors.
Correction: Preclinical Development of Ipilimumab and Nivolumab Combination Immunotherapy: Mouse Tumor Models, In Vitro
Overexpression of PD-1 and CD39 in tumor-infiltrating lymphocytes compared with peripheral blood lymphocytes in triple-n
- **DOI:** 10.14738/bjhr.1202.18696 - **Authors:** Tahir Abbas, V. Sundaram - **Year:** 2025 - **Journal:** British Jour
Recent advances in immunotherapy in cancer treatment.
Progress of Immune Checkpoint Inhibitors Therapy for pMMR/MSS Metastatic Colorectal Cancer.
Complete Response Associated With Combination Treatment Regorafenib and Sintilimab in a Sorafenib-refractory Hepatocellu
Nivolumab plus ipilimumab combination therapy for the first-line treatment NSCLC: evidence to date
Thymosin α1 Combined with PD-1/PD-L1 Inhibitor Plus Chemotherapy in Platinum-Resistant Recurrent Ovarian Cancer : A Retr
Tumor immunophenotyping-derived signature identifies prognosis and neoadjuvant immunotherapeutic responsiveness in gastr
Immune checkpoint inhibitors: the new frontier in non&ndash;small cell lung cancer treatment
Resistance Mechanism of PD-1/PD-L1 Blockade in the Cancer-Immunity Cycle.
Clinical utility of nivolumab in the treatment of advanced melanoma.
Immune Therapeutics in the Treatment of Advanced Gastric and Esophageal Cancer
Prospects for personalized combination immunotherapy for solid tumors based on adoptive cell therapies and immune checkp
Two Malignancies With Differential Responses to Immune Checkpoint Inhibitors: A Case Report.
Cytoreductive Nephrectomy After Combination of Nivolumab Plus Ipilimumab for Mucinous Tubular and Spindle Cell Carcinoma
Analysis of synergistic effects of PD-1 inhibitors and CTLA-4 inhibitors in HCC immunotherapy
STING activation reprograms tumor vasculatures and synergizes with VEGFR2 blockade.
Successful Treatment of Sarcomatoid Carcinoma Using Nivolumab Plus Ipilimumab Combination Immunotherapy: a Case Report
Metabolism and senescence in the immune microenvironment of osteosarcoma: focus on new therapeutic strategies
Clinical value of M1 macrophage-related genes identification in bladder urothelial carcinoma and in vitro validation
Influence of T Cell Coinhibitory Molecules on CD8+ Recall Responses
TIGIT and PD-1 Immune Checkpoint Pathways Are Associated With Patient Outcome and Anti-Tumor Immunity in Glioblastoma
Case Report: Thrombotic-Thrombocytopenic Purpura Following Ipilimumab and Nivolumab Combination Immunotherapy for Metast
Immunotherapy in cervical cancer: From the view of scientometric analysis and clinical trials
Limitations and potential of immunotherapy in ovarian cancer
Incorporation of Combination Immunotherapy into the Treatment Paradigms of Gastrointestinal Cancers
Current and emerging therapies for first line treatment of metastatic clear cell renal cell carcinoma
Plasma GDF15 levels associated with circulating immune cells predict the efficacy of PD-1/PD-L1 inhibitor treatment and
Strategies for treating the cold tumors of cholangiocarcinoma: core concepts and future directions.
Prognostic and Immunological Significance of TIPARP in Pancreatic Cancer.
Efficacy of dual checkpoint-blockade in solid tumors, part 1
Dual immune checkpoint blockade in gastroesophageal tumors: never say never
PD-L1 Tumor Expression as a Predictive Biomarker of Immune Checkpoint Inhibitors' Response and Survival in Advanced
Effective Combination Immunotherapy with Oncolytic Adenovirus and Anti-PD-1 for Treatment of Human and Murine Ovarian Ca
Immune Checkpoint Inhibitors' Associated Renal Toxicity: A Series of 12 Cases.
The Cellular and Molecular Immunotherapy in Prostate Cancer.
Cautious optimism-the current role of immunotherapy in gastrointestinal cancers.
[Dual Immunotherapy in Advanced Non-small Cell Lung Cancer: the Progress and Clinical Application].
Clinical outcomes and influencing factors of PD-1/PD-L1 in hepatocellular carcinoma.
The efficacy of third generation anti‑HER2 chimeric antigen receptor T�cells in combination with PD1 blockade against ma
Combined treatment of HCC with CTLA-4 inhibitors and PD-1/PD-L1 inhibitors: mechanisms, progress and challenges
Nivolumab in the treatment of thoracic cancer — new possibilities
Progress in Target-Therapy with Breast Cancer
Immunotherapy in Advanced Lung Cancer Treatment
Immune Escape and Immune Checkpoint-associated Therapies in the Tumour Microenvironment of Head and Neck Squamous Cell C
Cancer immunotherapy is accompanied by distinct metabolic patterns in primary and secondary lymphoid organs observed by
Surveilling the Potential for Precision Medicine-driven PD-1/PD-L1-targeted Therapy in HNSCC.
A Case of Immune-Mediated Pneumonitis Associated With Dual Nivolumab and Ipilimumab Immunotherapy Treatment.
Programmed Cell Death Protein 1 (PD-1) and Programmed Cell Death Ligand 1 (PD-L1) Immunotherapy: A Promising Breakthroug
The future of cancer treatment: immunomodulation, CARs and combination immunotherapy.
Detecting Early Response to Immune Checkpoint Blockade by Multimodal Molecular Imaging
Radio-Immune Response Modelling for Spatially Fractionated Radiotherapy
Distributed Biomarker Discovery for Immuno-Oncology
PD-1 inhibitor plus oncolytic vaccinia virus is a safe and effective treatment option for metastatic renal cell carcinom
Intradermal DNA vaccination combined with dual CTLA-4 and PD-1 blockade provides robust tumor immunity in murine melanom
Inosine shapes PD-1 blockade responses and synergizes with dual PD-1/CTLA-4 immunotherapy to enhance antitumor immunity.
Acute interstitial nephritis related to immune checkpoint inhibitors.
Interdependent IL-7 and IFN-γ signalling in T-cell controls tumour eradication by combined α-CTLA-4+α-PD-1 therapy.
Combining intratumoral Treg depletion with androgen deprivation therapy (ADT): preclinical activity in the Myc-CaP model
A novel mouse model for checkpoint inhibitor-induced adverse events.
Toxicological and pharmacological assessment of AGEN1884, a novel human IgG1 anti-CTLA-4 antibody.
CTLA-4 immunotherapy exposes differences in immune response along with different tumor progression in colorectal cancer.
m6A regulator-mediated methylation modification patterns and tumor microenvironment infiltration characterization in hep
BRAF inhibitors: resistance and the promise of combination treatments for melanoma.
Clinical features, diagnostic challenges, and management strategies in checkpoint inhibitor-related pneumonitis.
Combination Strategies of Checkpoint Immunotherapy in Metastatic Breast Cancer.
Successful treatment of synchronous double lung and colon cancers using immune checkpoint inhibitors.
Sequential JAK inhibition enhances antitumor immunity after combined anti-PD-1 and anti-CTLA4.
Predictive biomarkers of immunotherapy response with pharmacological applications in solid tumors.
Checkpoint blockade immunotherapy reshapes the high-dimensional phenotypic heterogeneity of murine intratumoural neoanti
Cancer cell plasticity defines response to immunotherapy in cutaneous squamous cell carcinoma.
Different tumour-resident memory T-cell subsets regulate responses to anti-PD-1 and anti-CTLA-4 cancer immunotherapies.
A reappraisal of CTLA-4 checkpoint blockade in cancer immunotherapy.
Intratumoral CD40 activation and checkpoint blockade induces T cell-mediated eradication of melanoma in the brain.
Plasma proteome profiling reveals dynamic of cholesterol marker after dual blocker therapy.
CMV serostatus is associated with improved survival and delayed toxicity onset following anti-PD-1 checkpoint blockade.
NLRC5/CITA expression correlates with efficient response to checkpoint blockade immunotherapy.
Nanobody-based CTLA4 inhibitors for immune checkpoint blockade therapy of canine cancer patients.
Baseline antibody profiles predict toxicity in melanoma patients treated with immune checkpoint inhibitors.
ICON: a randomized phase IIb study evaluating immunogenic chemotherapy combined with ipilimumab and nivolumab in patient
Transfer learning between preclinical models and human tumors identifies a conserved NK cell activation signature in ant
Tumor microenvironmental modification by the current target therapy for head and neck squamous cell carcinoma.
[Immune-related adverse events of immune checkpoint inhibitors].
Thyrotoxicosis and Adrenocortical Hormone Deficiency During Immune-checkpoint Inhibitor Treatment for Malignant Melanoma
[Dendritic cell and cancer immune checkpoint].
[Clinical practice and mechanism of endocrinological adverse events associated with immune checkpoint inhibitors].
Immunotherapeutic Innovations in Clear Cell Renal Cell Carcinoma: Current Strategies and Future Directions.
[Immune-related adverse events by immune checkpoint inhibitors].
Combined VLA-4-Targeted Radionuclide Therapy and Immunotherapy in a Mouse Model of Melanoma.
Quantitative CD3 PET Imaging Predicts Tumor Growth Response to Anti-CTLA-4 Therapy.
PD-1 Blockade Promotes Emerging Checkpoint Inhibitors in Enhancing T Cell Responses to Allogeneic Dendritic Cells.
A Gene Panel for Early Identification of Future Responders to Immune Checkpoint Blockade.
TGFβ2 Induces the Soluble Isoform of CTLA-4 - Implications for CTLA-4 Based Checkpoint Inhibitor Antibodies in Malignant
Characterization of a novel potency endpoint for the evaluation of immune checkpoint blockade in humanized mice.
The bladder cancer immune micro-environment in the context of response to immune checkpoint inhibition.
A surprising complete response to cadonilimab in a primary metastatic cervical cancer: a case report.
Development of caninized anti-CTLA-4 antibody as salvage combination therapy for anti-PD-L1 refractory tumors in dogs.
Immune Checkpoint Inhibition for Pancreatic Ductal Adenocarcinoma: Current Limitations and Future Options.
Holistic Approach to Immune Checkpoint Inhibitor-Related Adverse Events.
Immune checkpoint inhibitors associated cardiovascular immune-related adverse events.
Adenosine receptors on the immuno-oncology expressway: TIME, perspectives, and translation.
Beyond CTLA-4 and PD-1 Inhibition: Novel Immune Checkpoint Molecules for Melanoma Treatment.
Tumors Resistant to Checkpoint Inhibitors Can Become Sensitive after Treatment with Vascular Disrupting Agents.
Tumor Treating Fields (TTFields) Concomitant with Immune Checkpoint Inhibitors Are Therapeutically Effective in Non-Smal
Lymphocyte T Subsets and Outcome of Immune Checkpoint Inhibitors in Melanoma Patients: An Oncologist's Perspective
Nivolumab and Ipilimumab Acting as Tormentors of Advanced Tumors by Unleashing Immune Cells and Associated Collateral Da
Pseudomonas Exotoxin Immunotoxins and Anti-Tumor Immunity: From Observations at the Patient's Bedside to Evaluation
Releasing the brakes: the role of immune checkpoint inhibitors in laryngeal cancer.
Analysis of the TCRβ repertoire characteristics when combining radiotherapy and immunotherapy in cancer.
Current status of immune checkpoint inhibitors in treatment of non-small cell lung cancer.
Immune-Checkpoint Inhibitors-Induced Type 1 Diabetes Mellitus: From Its Molecular Mechanisms to Clinical Practice.
Current Status and Future Direction of Immunotherapy in Hepatocellular Carcinoma: What Do the Data Suggest?
Immunotherapy of melanoma.
Immunological Agents Used in Cancer Treatment.
TGF-β inhibition combined with cytotoxic nanomedicine normalizes triple negative breast cancer microenvironment towards
Influence of Microbiome and Antibiotics on the Efficacy of Immune Checkpoint Inhibitors.
Immunotherapy-Induced Anterior Hypophysitis.
An Uncommon Case of Myocarditis Secondary to Durvalumab Plus Tremelimumab.
Evaluation of CTLA-4 and PD-L1 Expression in Thyroid Carcinoma and Its Prognostic Significance.
Combination checkpoint inhibitors for treatment of non-small-cell lung cancer: an update on dual anti-CTLA-4 and anti-PD
Case report: Fatal overwhelming post-splenectomy infection in a patient with metastatic angiosarcoma treated with immuno
Advances in immunotherapy for thyroid malignancies: from molecular targets to clinical outcomes.
225Actinium-armed antibody targeting CCR8+ regulatory T cells synergizes with immunotherapy to promote tumor rejection i
PD-1 and CTLA-4 serve as major gatekeepers for effector and cytotoxic T-cell potentiation by limiting a CXCL9/10-CXCR3-I
Current Advances in Checkpoint Inhibitors: Lessons from Non-Central Nervous System Cancers and Potential for Glioblastom
Anti-PD-1 and Anti-CTLA-4 Therapies in Cancer: Mechanisms of Action, Efficacy, and Limitations.
Current status of clinical trial research and application of immune checkpoint inhibitors for non-small cell lung cancer
Immune Checkpoint Inhibitors in the Treatment of HCC.
Overcoming the cardiac toxicities of cancer therapy immune checkpoint inhibitors.
LAG3 immune inhibitors: a novel strategy for melanoma treatment.
Cadonilimab (PD-1/CTLA-4 bispecific antibody) combination therapy for driver gene-negative advanced NSCLC: a single-cent
Clinical Insights Into Novel Immune Checkpoint Inhibitors.
The Role of Immunotherapy in the Treatment of Adrenocortical Carcinoma.
Interplay between Tumor Mutational Burden and Mutational Profile and Its Effect on Overall Survival: A Pilot Study of Me
Lung Cancer Immunotherapy: Beyond Common Immune Checkpoints Inhibitors.
The Immune Landscape and Immunotherapeutic Strategies in Platinum-Refractory Testicular Germ Cell Tumors.
Targeting Multiple Receptors to Increase Checkpoint Blockade Efficacy.
Molecular Mechanisms of Cutaneous Immune-Related Adverse Events (irAEs) Induced by Immune Checkpoint Inhibitors.
Stoking an anti-liver cancer immune response with cryoablation plus an intratumoral TLR9 agonist and dual checkpoint inh
Beyond checkpoint inhibitors: the three generations of immunotherapy.
Janus kinase inhibitor overcomes resistance to immune checkpoint inhibitor treatment in peritoneal dissemination of gast
Mapping endocrine toxicity spectrum of immune checkpoint inhibitors: a disproportionality analysis using the WHO adverse
The suppressive effect of co-inhibiting PD-1 and CTLA-4 expression on H22 hepatomas in mice.
Immune checkpoint inhibitors therapy in older patients (≥ 70 years) with metastatic melanoma: a multicentre study.
Page, David B.
David.page2@providence.org
Immunotherapy in Triple-Negative Breast Cancer: Present and Future
ViewKatsuki, Shohei
skatsuki@sahs.med.osaka-u.ac.jp
Radiation Dose Escalation is Crucial in Anti-CTLA-4 Antibody Therapy to Enhance Local and Distant Antitumor Effect in Mu
ViewSilvestris, Nicola
n.silvestris@oncologico.bari.it
The Role of V-Domain Ig Suppressor of T Cell Activation (VISTA) in Cancer Therapy: Lessons Learned and the Road Ahead.
ViewCeleste; Tartour, Eric
eric.tartour@aphp.fr
Soluble CD27 differentially predicts resistance to anti-PD1 alone but not with anti-CTLA-4 in melanoma.
ViewAscierto, Paolo A; Bruzzi
paolo.ascierto@gmail.com
The great debate at "Melanoma Bridge 2018", Naples, December 1st, 2018.
ViewGlen; Schmidt-Wolf, Ingo G H
Ingo.Schmidt-Wolf@ukbonn.de
Anti-CD40 predominates over anti-CTLA-4 to provide enhanced antitumor response of DC-CIK cells in renal cell carcinoma.
ViewRapoport, Bernardo Leon
bernardo.rapoport@up.ac.za
Editorial: Management of Immune-Related Adverse Events for Patients Undergoing Treatment With Checkpoint Inhibitors.
Viewbo.zhu@tmmu.edu.cn
Type I interferon-mediated tumor immunity and its role in immunotherapy
m.j.m.vaneijs-2@umcutrecht.nl
Toxicity-specific peripheral blood T and B cell dynamics in anti-PD-1 and combined immune checkpoint inhibition
KFLAHERTY@mgh.harvard.edu
Mechanisms of resistance to immune checkpoint inhibitors
glenn_dranoff@dfci.harvard.edu
Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints
huangmingxin2001@sina.com
PD-1 and TIGIT Are Highly Co-Expressed on CD8+ T Cells in AML Patient Bone Marrow
tengfeifei16@126.com
Efficacy and Safety of Anti-PD-1 Plus Anlotinib in Patients With Advanced Non–Small-Cell Lung Cancer After Previous Syst
julian.steininger@uniklinikum-dresden.de
Systemic Therapy of Metastatic Melanoma: On the Road to Cure
hiro.sato@gunma-u.ac.jp
A Promising Treatment Strategy for Lung Cancer: A Combination of Radiotherapy and Immunotherapy
giulia.martini@unicampania.it
How Immunotherapy Has Changed the Continuum of Care in Hepatocellular Carcinoma
daniele.lavacchi@yahoo.it
Immune Checkpoint Inhibitors in the Treatment of Renal Cancer: Current State and Future Perspective
geoffrey.bryant@mssm.edu
Overcoming Oncogenic Mediated Tumor Immunity in Prostate Cancer
aneta.cheda@wihe.pl
Effects of a Unique Combination of the Whole-Body Low Dose Radiotherapy with Inactivation of Two Immune Checkpoints and/
p.ascierto@istitutotumori.na.it
Perspectives in melanoma: Meeting report from the Melanoma Bridge (30 November–2 December, 2017, Naples, Italy)
jliu@stat.harvard.edu
Comprehensive analyses of tumor immunity: implications for cancer immunotherapy
chenxiaofengnjmu@163.com
Current Progress and Future Perspectives of Immune Checkpoint Inhibitors in Biliary Tract Cancer
vera.hirsh@muhc.mcgill.ca
New developments in the treatment of advanced squamous cell lung cancer: focus on afatinib
marina.bacac@roche.com
Combination of T-Cell Bispecific Antibodies With PD-L1 Checkpoint Inhibition Elicits Superior Anti-Tumor Activity
xurh@sysucc.org.cn
Gastric cancer treatment: recent progress and future perspectives
xlzeng915@gmu.edu.cn
Overcoming immune evasion with innovative multi-target approaches for glioblastoma
yichen_zhou_mds@163.com
An update on the clinical trial research of immunotherapy for glioblastoma.
drsongliang@163.com
Advances in PD-1 and CTLA-4 dual-target immunotherapy for ovarian cancer.
Wufeng03@126.com
New dimensions of PD-1/PD-L1 inhibitor combination therapy in cancer treatment: current advances and future perspectives
liwei10@suda.edu.cn
Multi-omics analyses inform mechanisms of immunotherapy response in pancreatic cancer
fengbincn@126.com
The impact of immunotherapy on the prognosis of small cell carcinoma of the esophagus: a propensity score-matched analys
zhaochen0115@126.com
Reprogramming the immunosuppressive breast cancer microenvironment: integrating cellular, metabolic, and stromal targets
guanxg@ciac.ac.cn
Dual checkpoint blockade of PD-1 and Tim-3 by engineered hybrid nanovesicles for enhanced cancer immunotherapy
thangavel.chellappagounder@jefferson.edu
Editorial: Unveiling the next generation of cancer immunity & immunotherapy.
jianghaihui@bjmu.edu.cn
Editorial: Combination immunotherapy and immune response assessment of brain tumours.
zhangpeng@link.cuhk.edu.hk
PRKAR1B as an oncogenic biomarker for diagnostic and prognostic stratification of tumor immunity, proliferation, and mig
kennethto@cuhk.edu.hk
Immunotherapy in Treating EGFR-Mutant Lung Cancer: Current Challenges and New Strategies
fangjian5555@yeah.net
Immune-Related Adverse Events and Their Association With the Effectiveness of PD-1/PD-L1 Inhibitors in Non-Small Cell Lu
ann_silk@dfci.harvard.edu
A phase Ib study of interleukin-2 plus pembrolizumab for patients with advanced melanoma.
yongyuan@scu.edu.cn
Overcoming resistance to PD-1/PD-L1 inhibitors in esophageal cancer.
tingting.huang@ki.se
An Update on the Immunotherapy for Oropharyngeal Squamous Cell Carcinoma
dimitrios.mougiakakos@med.ovgu.de
TIGIT signaling and its influence on T cell metabolism and immune cell function in the tumor microenvironment
imyh00@skku.edu
Lymphocyte-activating gene 3 expression in tumor cells predicts immune checkpoint inhibitor response in triple negative
wangny@jlu.edu.cn
Comparison analysis of PD-1/PD-L1 inhibitors plus lenvatinib or gemcitabine/cisplatin as first-line treatment for patien
samantha.low3@nhs.scot
Case report: A rare case of immunotherapy induced isolated left CN VI palsy in a patient with unresectable melanoma.
liyongdoctor@126.com
Immunotherapy in the perioperative management of esophageal squamous cell carcinoma: recent developments.
fengxiushan2004@126.com
CIK-augmented anti-PD1/CTLA4 immunotherapy eradicates chemo-resistant ovarian cancer via tripartite mechanistic synergy.
gaofengwei@scu.edu.cn
Case Report: Dual checkpoint inhibition with bevacizumab yields dramatic response in synchronous double primary HCC and
fulw@mail.sysu.edu.cn
PD-1/PD-L1 Based Combinational Cancer Therapy: Icing on the Cake.
chaymaker@mdanderson.org
Next-Generation Immunotherapies to Improve Anticancer Immunity.
kimmel.85@osu.edu
Modular Nanobody Conjugates with Controlled Topology Using Genetically Encoded Non-canonical Amino Acids
xitao18@hotmail.com
Combined SEP and anti-PD-L1 antibody produces a synergistic antitumor effect in B16-F10 melanoma-bearing mice
georgina.long@sydney.edu.au
Neoadjuvant triplet immune checkpoint blockade in newly diagnosed glioblastoma
yue.liu@antibodytherapeutics.com
Fc-competent multispecific PDL-1/TIGIT/LAG-3 antibodies potentiate superior anti-tumor T cell response
zhongzhenwei@oricell.com
Development of a bispecific antibody targeting PD-L1 and TIGIT with optimal cytotoxicity
mdpagel2@wisc.edu
Potentiation of immune checkpoint blockade with an ITPP radiosensitizer studied with oxygen saturation measurements from
koie.takuya.h2@f.gifu-u.ac.jp
Efficacy and safety of combination immunotherapy for treating advanced non-clear cell renal cell carcinoma: A multicente
teh.bin.tean@singhealth.com.sg
Spatial transcriptomics reveal topological immune landscapes of Asian head and neck angiosarcoma
Heather.McArthur@cshs.org
Immunotherapy in Breast Cancer: the New Frontier.
ruwang@mail.ccmu.edu.cn
Exploring the frontiers: tumor immune microenvironment and immunotherapy in head and neck squamous cell carcinoma
huwenjian_7707@163.com
Unraveling the immunomodulatory role of TIM-3 in head and neck squamous cell carcinoma: implications for targeted therap
Alexander.Vanakkooi@melanoma.org.au
Neoadjuvant Immune Checkpoint Inhibitor Therapy in Melanoma: Efficacy, Safety and Timing.
Bertram.bengsch@uniklinik-freiburg.de
Incidence and severity of immune-related hepatitis after dual checkpoint therapy is linked to younger age independent of
shenjie2008nju@163.com
Multiplex immunohistochemistry to explore the tumor immune microenvironment in HCC patients with different GPC3 expressi
weiqinjiang@zju.edu.cn
Soluble PD-L1: a potential dynamic predictive biomarker for immunotherapy in patients with proficient mismatch repair co
hnagano@yamaguchi-u.ac.jp
Predictive biomarkers for the efficacy of peptide vaccine treatment: based on the results of a phase II study on advance
sbucktrout@parkerici.org
Recent advances in immunotherapies: from infection and autoimmunity, to cancer, and back again.
Tian.Zhang2@Duke.edu
Association of baseline neutrophil-to-eosinophil ratio with response to nivolumab plus ipilimumab in patients with metas
Joannakefas@nhs.net
Small vessel vasculitis and dry gangrene secondary to combined CTLA-4 and PD-1 blockade in malignant mesothelioma
egaughan@virginia.edu
Severe combined cardiac and neuromuscular toxicity from immune checkpoint blockade: an institutional case series.
wangjing@cicams.ac.cn
PD-1/PD-L1 Inhibitor-Associated Myocarditis: Epidemiology, Characteristics, Diagnosis, Treatment, and Potential Mechanis
zhengyuli@scu.edu.cn
Positive clinical outcomes following therapy with programmed cell death protein 1/programmed cell death ligand 1 inhibit
jiangyu@pumc.edu.cn
Editorial: Toxicity Mechanism and Clinical Features of PD-1/PD-L1 Inhibitors in Treatment of Cancer, Volume I.
xifengliu@126.com
Exosome CTLA-4 Regulates PTEN/CD44 Signal Pathway in Spleen Deficiency Internal Environment to Promote Invasion and Meta
sallyma1201@163.com
A network comparison on efficacy and safety profiling of PD-1/PD-L1 inhibitors in first-line treatment of advanced non-s
yizhang@zzu.edu.cn
Drug resistance mechanism and reversal strategy in lung cancer immunotherapy.
wangtingyaoli@foxmail.com
Concurrent immune checkpoint blockade for enhanced cancer immunotherapy utilizing engineered hybrid nanovesicles.
zarema.albakova14@gmail.com
Impaired Heat Shock Protein Expression in Activated T Cells in B-Cell Lymphoma.
annelies.janssens@uza.be
Recent Advances of Immune Checkpoint Inhibition and Potential for (Combined) TIGIT Blockade as a New Strategy for Malign
laurent.gorvel@inserm.fr
Endometrial Carcinoma: Immune Microenvironment and Emerging Treatments in Immuno-Oncology.
aerman@onko-i.si
The Prognostic and Predictive Value of Human Gastrointestinal Microbiome and Exosomal mRNA Expression of PD-L1 and IFNγ
lisda.suteja@nccs.com.sg
Establishment and Characterization of Humanized Mouse NPC-PDX Model for Testing Immunotherapy
nageshwar.budha@beigene.com
Targeting TIGIT for Immunotherapy of Cancer: Update on Clinical Development
okuno.scott@mayo.edu
A Retrospective Analysis of the Efficacy of Immunotherapy in Metastatic Soft-Tissue Sarcomas
david.tai.w.m@singhealth.com.sg
Rationale of Immunotherapy in Hepatocellular Carcinoma and Its Potential Biomarkers.
dbansal@wustl.edu
Immunotherapy and Immunotherapy Combinations in Metastatic Castration-Resistant Prostate Cancer.
stanislav.pantelyushin@uzh.ch
Cross-Reactivity and Functionality of Approved Human Immune Checkpoint Blockers in Dogs
ramonmello@med.up.pt
Mutations Associated with No Durable Clinical Benefit to Immune Checkpoint Blockade in Non-S-Cell Lung Cancer.
matthew.tucker@vumc.org
Predicting Response to Immunotherapy in Metastatic Renal Cell Carcinoma.
piero.delboccio@unich.it
Phenotypic and Proteomic Analysis Identifies Hallmarks of Blood Circulating Extracellular Vesicles in NSCLC Responders t
miguel.torralba@uah.es
Anti-PD-1/PD-L1 Based Combination Immunotherapy to Boost Antigen-Specific CD8+ T Cell Response in Hepatocellular Carcino
elena.shklovskaya@mq.edu.au
Tumor MHC Expression Guides First-Line Immunotherapy Selection in Melanoma.
gkim@aumc.ac.kr
Combination Immunotherapies to Overcome Intrinsic Resistance to Checkpoint Blockade in Microsatellite Stable Colorectal
nkarin@technion.ac.il
Chemokines in the Landscape of Cancer Immunotherapy: How They and Their Receptors Can Be Used to Turn Cold Tumors into H
alessandra.raimondi@istitutotumori.mi.it
TremelImumab and Durvalumab Combination for the Non-OperatIve Management (NOM) of Microsatellite InstabiliTY (MSI)-High
andrew.hendifar@cshs.org
Immunotherapy Updates in Advanced Hepatocellular Carcinoma
katy.beckermann@vumc.org
Emerging Targets in Clear Cell Renal Cell Carcinoma.
fyao@mail.hzau.edu.cn
Immunotherapeutic Approaches for Treating Hepatocellular Carcinoma.
yangd@mail.nih.gov
Regression and Eradication of Triple-Negative Breast Carcinoma in 4T1 Mouse Model by Combination Immunotherapies
christina.bruss@ukr.de
Immune Checkpoint Profiling in Humanized Breast Cancer Mice Revealed Cell-Specific LAG-3/PD-1/TIM-3 Co-Expression and El
li.shenduo@mayo.edu
Heterogeneous Expression of PD-L1, B7x, B7-H3, and HHLA2 in Pulmonary Sarcomatoid Carcinoma and the Related Regulatory S
rajana@mail.nih.gov
Immunotherapy for Thymomas and Thymic Carcinomas: Current Status and Future Directions
amedeonuzzo@gmail.com
Immune Checkpoint Inhibitor Rechallenge in Renal Cell Carcinoma: Current Evidence and Future Directions
ewakalinka@wp.pl
Double Guard Efficiency and Safety-Overcoming Resistance to Immunotherapy by Blocking or Stimulating Several Immune Chec
percylee@coh.org
Novel Immunotherapeutics for the Treatment of Non-Small Cell Lung Cancer (NSCLC) Resistant to PD-1/PD-L1 Inhibitors.
maofuling@tmu.edu.cn
Immune Checkpoint Therapy for Thymic Carcinoma
gantumur.battogtokh@howard.edu
Recent Developments in Combination Immunotherapy with Other Therapies and Nanoparticle-Based Therapy for Triple-Negative
sercan.on@ege.edu.tr
Real-World Treatment Patterns and Survival in Uveal Melanoma: A Multicenter Cohort Study by the Turkish Oncology Group (
katharine.collier@osumc.edu
Emerging Immunotherapy Approaches for Advanced Clear Cell Renal Cell Carcinoma.
namrata.anand@bsd.uchicago.edu
Bridging Immune Evasion and Vascular Dynamics for Novel Therapeutic Frontiers in Hepatocellular Carcinoma.
ptriozzi@wakehealth.edu
Metabolic Implications of Immune Checkpoint Proteins in Cancer.
t.gambichler@klinikum-bochum.de
Rapid Melanoma Death of an Adult Male with Congenital Bathing Trunk Nevus despite Initiation of Combination Immunotherap
gracelfu@szu.edu.cn
[Research Progress in Immunosuppressive Tumor Microenvironment of Gastrointestinal Cancer].
gavitt.woodard@yale.edu
Increased Lymphocyte Infiltration in NSCLC Neoadjuvant Chemo-Immunotherapy Non-responders: A Biomarker of T-Cell Dysfunc
ytakahashi@radonc.med.osaka-u.ac.jp
Radiation enhanced the local and distant anti-tumor efficacy in dual immune checkpoint blockade therapy in osteosarcoma.
Ahmad.Tarhini@moffitt.org
CTLA-4 blockade and interferon-α induce proinflammatory transcriptional changes in the tumor immune landscape that corre
gennadiy.zelinskyy@uni-due.de
Combination immunotherapy with anti-PD-L1 antibody and depletion of regulatory T cells during acute viral infections res
ytakahashi@sahs.med.osaka-u.ac.jp
Radiation therapy enhances systemic antitumor efficacy in PD-L1 therapy regardless of sequence of radiation in murine os
fskoulidis@mdanderson.org
CTLA4 blockade abrogates KEAP1/STK11-related resistance to PD-(L)1 inhibitors
qlgao@tjh.tjmu.edu.cn
Harnessing the potential of HLA-G in cancer therapy: advances, challenges, and prospects
lianyu-chen@alu.fudan.edu.cn
Combination immunotherapy in hepatocellular carcinoma: synergies among immune checkpoints, TKIs, and chemotherapy.
khyoung@mdanderson.org
PD-1/PD-L1 Blockade: Have We Found the Key to Unleash the Antitumor Immune Response?
johan.park0@gmail.com
Combination of PD-1/PD-L1 and CTLA-4 inhibitors in the treatment of cancer - a brief update.
tangying@gzucm.edu.cn
OX40 signaling in cancer immunotherapy: mechanisms of action, translational applications, and therapeutic perspectives.
zhouyichan@163.com
Various Uses of PD1/PD-L1 Inhibitor in Oncology: Opportunities and Challenges.
alexandr.bazhin@med.uni-muenchen.de
Dendritic Cells in Anticancer Vaccination: Rationale for Ex Vivo Loading or In Vivo Targeting.
martina.delsignore@uniupo.it
Determinants of Response to Immune Checkpoint Blockade in Pleural Mesothelioma: Molecular, Immunological, and Clinical P
norihiro.imai@gmail.com
Decision-Making Biomarkers Guiding Therapeutic Strategies in Hepatocellular Carcinoma: From Prediction to Personalized C
f_alrumaihi@qu.edu.sa
Cancer Vaccines: Molecular Mechanisms, Clinical Progress, and Combination Immunotherapies with a Focus on Hepatocellular
jheo@pusan.ac.kr
Therapeutic Strategies for Hepatocellular Carcinoma: Current Advances and Future Perspectives.
sunjin@syphu.edu.cn
Inhibition of Post-Surgery Tumour Recurrence via a Sprayable Chemoimmunotherapy Gel Releasing PD-L1 Antibody and Platele
wangling2016uw@126.com
The Updated Status and Future Direction of Immunotherapy Targeting B7-H1/PD-1 in Osteosarcoma
jonathan.zager@moffitt.org
Combination Atezolizumab, Cobimetinib, and Vemurafenib as a Treatment Option in BRAF V600 Mutation-Positive Melanoma: Pa
ruantingyan165@163.com
Total T Cell Density and Expression of T Memory Stem Cell Markers are Associated with Better Prognosis in Colon Cancer
praveen-vikas@uiowa.edu
The clinical promise of immunotherapy in triple-negative breast cancer
yousef-zakharia@uiowa.edu
Spotlight on nivolumab in the treatment of renal cell carcinoma: design, development, and place in therapy.
rizzo.alessandro179@gmail.com
Immune-Based Combination Therapies for Advanced Hepatocellular Carcinoma.
nseetharamu@northwell.edu
New PD-L1 inhibitors in non-small cell lung cancer – impact of atezolizumab
nick.pavlakis@sydney.edu.au
An Update on Emerging Therapeutic Options for Malignant Pleural Mesothelioma.
gehong616@126.com
Immune checkpoint inhibitors in esophageal squamous cell carcinoma: progress and opportunities.
drzhuhui@163.com
PD-1/PD-L1 blockades in non-small-cell lung cancer therapy.
huyi_0912@126.com
Clinical observation of immune checkpoint inhibitors in the treatment of advanced pancreatic cancer: a real-world study
huangzy@tjh.tjmu.edu.cn
Complete Response to the Sequential Treatment with Regorafenib Followed by PD-1 Inhibitor in a Sorafenib-Refractory Hepa
ramondemello@gmail.com
Potential role of immunotherapy in advanced non-small-cell lung cancer.
hrsmasuda@yahoo.co.jp
Successful Response to Nivolumab Plus Ipilimumab Therapy in a Hemodialysis Patient With Metastatic Renal Cell Carcinoma.
joseph.dolina@pfizer.com.
Linked CD4+/CD8+ T cell neoantigen vaccination overcomes immune checkpoint blockade resistance and enables tumor regress
lida@bjtth.org
Prognostic and predictive value of an immune infiltration signature in diffuse lower-grade gliomas.
i.samoylenko@ronc.ru
Efficacy and safety of nurulimab+prolgolimab with continued prolgolimab therapy compared to prolgolimab alone as first-l
yuelillin@163.com
Biomimetic nanoparticles for tumor immunotherapy
songdong@jlu.edu.com
Transglutaminase 2 in breast cancer metastasis and drug resistance.
anyue_cmu@163.com
Establishment and Validation of a Genetic Label Associated With M2 Macrophage Infiltration to Predict Survival in Patien
jingshan_huang@126.com
Determination of a prediction model for therapeutic response and prognosis based on chemokine signaling-related genes in
kamal.khanna@nyumc.org
Combination Immunotherapy: Taking Cancer Vaccines to the Next Level
chencheng@suda.edu.cn
IL36 Cooperates With Anti-CTLA-4 mAbs to Facilitate Antitumor Immune Responses
yongqin@mdanderson.org
Hypoxia-Driven Immunosuppressive Metabolites in the Tumor Microenvironment: New Approaches for Combinational Immunothera
huang@tju.edu.cn
Research Progress and Applications of Multivalent, Multispecific and Modified Nanobodies for Disease Treatment
Valerie.chew.s.p@singhealth.com.sg
Combinational Immunotherapy for Hepatocellular Carcinoma: Radiotherapy, Immune Checkpoint Blockade and Beyond
jbell@ohri.ca
Oncolytic virus driven T-cell-based combination immunotherapy platform for colorectal cancer.
heyingchun@hnucm.edu.cn
Hyperthermia combined with immune checkpoint inhibitor therapy in the treatment of primary and metastatic tumors
xhyang4933@vip.sina.com
Immunological Classification of Tumor Types and Advances in Precision Combination Immunotherapy.
yhua@shsmu.edu.cn
Immune Microenvironment in Osteosarcoma: Components, Therapeutic Strategies and Clinical Applications
zhaoht@pumch.cn
Efficacy and safety of lenvatinib combined with PD-1/PD-L1 inhibitors plus Gemox chemotherapy in advanced biliary tract
shuomingluo@csu.edu.cn
Characterization of immune checkpoint inhibitor-associated fulminant type 1 diabetes associated with autoantibody status
zhongxiangyu@hrbmu.edu.com
Tertiary lymphoid structures in pancreatic cancer: a new target for immunotherapy
donlonn@tcd.ie
The future of combination immunotherapy in oesophageal adenocarcinoma.
justin.david@bms.com
Comprehensive immunophenotyping of solid tumor-infiltrating immune cells reveals the expression characteristics of LAG-3
akcheung@hkbu.edu.hk
Anti-PD1 does not improve pyroptosis induced by γδ T cells but promotes tumor regression in a pleural mesothelioma mouse
shao_qx@ujs.edu.cn
Hierarchical transcriptional network governing heterogeneous T cell exhaustion and its implications for immune checkpoin
xiangy@pumch.cn
The anti-PD-1 era of cervical cancer: achievement, opportunity, and challenge
baozhenjnu@126.com
Overcoming cold tumors: a combination strategy of immune checkpoint inhibitors
zyzhang@cmu.edu.cn
Immunotherapy of osteosarcoma based on immune microenvironment modulation
fang_li@tongji.edu.cn
Single‐cell dissection of cervical cancer reveals key subsets of the tumor immune microenvironment
jacob.stein@unc.edu
Maximizing Immunotherapy in Sarcoma Using Histology, Biomarkers and Novel Approaches
patel@ucsd.edu
Rapid onset type 1 diabetes with anti-PD-1 directed therapy.
Lucie.Heinzerling@uk-erlangen.de
Real world experience in low-dose ipilimumab in combination with PD-1 blockade in advanced melanoma patients.
wayne_marasco@dfci.harvard.edu
Chimeric antigen receptor T cells secreting anti-PD-L1 antibodies more effectively regress renal cell carcinoma in a hum
tkuo@mdanderson.org
Improving radiotherapy in cancer treatment: Promises and challenges
liym@lzu.edu.cn
The advances in immunotherapy for hepatocellular carcinoma
hrgarber@mdanderson.org
Durvalumab and tremelimumab before surgery in patients with hormone receptor positive, HER2-negative stage II-III breast
julita.kulbacka@umw.edu.pl
TIM-3 as a promising target for cancer immunotherapy in a wide range of tumors
claudia.maletzki@med.uni-rostock.de
Combined vaccine-immune-checkpoint inhibition constitutes a promising strategy for treatment of dMMR tumors
Krishna.S.Gunturu@lahey.org
Immune checkpoint inhibitors: immune-related adverse events, healthcare utilization, and costs among commercial and Medi
dyyyliuyan@163.com
Immunotherapy for the treatment of advanced nasopharyngeal carcinoma: a promising new era.
pashtoon-kasi@uiowa.edu
Immune Checkpoint Inhibitors in Metastatic Colorectal Cancer: Current Status, Recent Advances, and Future Directions
Bruna.Pellini@moffitt.org
Immune Checkpoint Inhibitors and Chemoradiation for Limited-Stage Small Cell Lung Cancer
alfredo.addeo@hcuge.ch
Current Approaches to Neoadjuvant Immunotherapy in Resectable Non-small Cell Lung Cancer
dirk.schadendorf@uk-essen.de
The Latest Option: Nivolumab and Relatlimab in Advanced Melanoma
yuanjiahu@um.edu.mo
A target map of clinical combination therapies in oncology: an analysis of clinicaltrials.gov.
lucy.corke@uhn.ca
New Strategies and Combinations to Improve Outcomes in Immunotherapy in Metastatic Non-Small-Cell Lung Cancer.
francesco.massari@aosp.bo.it
Is There a Role for Immunotherapy in Prostate Cancer?
m.yerolatsite@gmail.com
Exploring a Rarity: Incidence of and Therapeutic Approaches for Neurological Complications and Hypophysitis in Cancer Pa
cmoh@gist.ac.kr
Combination Immunotherapy Using Oncolytic Virus for the Treatment of Advanced Solid Tumors.
jennifer.peil@uk-koeln.de
New Therapeutic Approaches for Conjunctival Melanoma-What We Know So Far and Where Therapy Is Potentially Heading: Focus
michela.guardascione@cro.it
Immune Checkpoint Inhibitors as Monotherapy or Within a Combinatorial Strategy in Advanced Hepatocellular Carcinoma
tanaka.masatake.656@m.kyushu-u.ac.jp
Advances in Systemic Therapy for Hepatocellular Carcinoma and Future Prospects.
luon11@nankai.edu.cn
Rationale and Clinical Research Progress on PD-1/PD-L1-Based Immunotherapy for Metastatic Triple-Negative Breast Cancer.
chiara.riganti@unito.it
Strategies to Overcome Resistance to Immune-Based Therapies in Osteosarcoma
christian.linares@nhs.net
Hallmarks of the Tumour Microenvironment of Gliomas and Its Interaction with Emerging Immunotherapy Modalities
narayanan.sadagopan@medstar.net
Recent Progress in Systemic Therapy for Advanced Hepatocellular Carcinoma
jhlee0811@yuhs.ac
Combining Cancer Vaccines with Immunotherapy: Establishing a New Immunological Approach.
hajjc@mskcc.org
Radiation and Immune Checkpoint Inhibitors: Combination Therapy for Treatment of Hepatocellular Carcinoma.
bo.gao@health.nsw.gov.au
Small-Cell Lung Cancer-An Update on Targeted and Immunotherapies.
a.zaravinos@euc.ac.cy
Immune Cytolytic Activity and Strategies for Therapeutic Treatment
giovanni.brandi@unibo.it
Improvements in Systemic Therapies for Advanced Malignant Mesothelioma.
mark.qian@takeda.com
Development of a Highly Sensitive Hybrid LC/MS Assay for the Quantitative Measurement of CTLA-4 in Human T Cells.
mathilde.bausart@uclouvain.be
Combination of DNA Vaccine and Immune Checkpoint Blockades Improves the Immune Response in an Orthotopic Unresectable Gl
Raluca-Ileana.Mincu@uk-essen.de
ECG Changes in Melanoma Patients Undergoing Cancer Therapy-Data From the ECoR Registry.
samir.dalia@mercy.net
- **Authors:** Karri, Veera Venkata Satyanarayana Reddy, Dalia, Samir - **Year:** 2025 - **Journal:** Tumor Discovery -
yuko.oya.710@gmail.com
It might be a dead end: immune checkpoint inhibitor therapy in EGFR-mutated NSCLC.
gzzhouqing@126.com
[First-line Combination Immunotherapy in Advanced Non-small Cell Lung Cancer].
liaozhengyin@163.com
Current progress and prospect of immune checkpoint inhibitors in hepatocellular carcinoma.
xiujuanqu@yahoo.com
[Research Progress of Adverse Events Related to PD-1/PD-L1 Inhibitors Based Combination Therapy].
cgridelli@libero.it
Untitled
zhuyaqi@pku.org.cn
Immune Checkpoint Inhibitors for Triple-Negative Breast Cancer
XiaofengLu@stu.xjtu.edu.cn
Combination Strategies for PD-1-Based Immunotherapy in Breast Cancer
sheng.tong@uky.edu
Spatially confined genome editing enables localized combination immunotherapy.
xuanlixuepumc@126.com.
PD-1/PD-L1 Inhibitor - Related Adverse Events and Their Management in Breast Cancer.
hexiaoyun@csu.edu.cn
Comprehensive analysis of prognostic value and immune infiltration of IAPs family in hepatocellular carcinoma
RSULLIVAN7@mgh.harvard.edu.
Phase 1b Study of Tovorafenib, Plozalizumab or Vedolizumab Plus Standard-of-Care Immune Checkpoint Inhibitors in Patient
ramburuth@gmail.com
Thyroid Storm and Type 1 Diabetes Mellitus Induced by Combined Ipilimumab and Nivolumab Immunotherapy: A Case Report.
chandan.sanghera14@imperial.ac.uk
Immunotherapy - Strategies for Expanding Its Role in the Treatment of All Major Tumor Sites.
sunnan@vip.126.com
Nivolumab plus ipilimumab: a potential regimen to rewrite treatment guidelines for ESCC
xingxiaofang@bjmu.edu.cn
Tumor-infiltrating immune cell profiles and changes associate with additional trastuzumab in preoperative chemotherapy f
xieweimin@gxmu.edu.cn
Oncolytic adenoviruses synergistically enhance anti-PD-L1 and anti-CTLA-4 immunotherapy by modulating the tumour microen
xingxing.zang@einsteinmed.edu
The immune checkpoint B7x expands tumor-infiltrating Tregs and promotes resistance to anti-CTLA-4 therapy
aurelien.marabelle@gustaveroussy.fr
PD-Loma: a cancer entity with a shared sensitivity to the PD-1/PD-L1 pathway blockade.
drenouf@bccancer.bc.ca
The CCTG PA.7 phase II trial of gemcitabine and nab-paclitaxel with or without durvalumab and tremelimumab as initial th
achapuis@fredhutch.org
Acquired cancer resistance to combination immunotherapy from transcriptional loss of class I HLA
isabelle.ray-coquard@lyon.unicancer.fr
Neoadjuvant immune checkpoint blockade before chemoradiation for cervical squamous carcinoma (GINECO window-of-opportuni
chendm29@mail.sysu.edu.cn
Resistance to anti-LAG-3 plus anti-PD-1 therapy in head and neck cancer is mediated by Sox9+ tumor cells interaction wit
jatoi@uthscsa.edu
Hypothesis: can the abscopal effect explain the impact of adjuvant radiotherapy on breast cancer mortality?
katharina.hopp@cuanschutz.edu
Immune Checkpoint Activity Regulates Polycystic Kidney Disease Progression
joseph.dolina@pfizer.com
Linked CD4 + /CD8 + T cell neoantigen vaccination overcomes immune checkpoint blockade resistance and enables tumor regr
pankaj-singh@ouhsc.edu
DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation.
Adil.Daud@ucsf.edu
Partially exhausted tumor-infiltrating lymphocytes predict response to combination immunotherapy.
huangb48@mail.sysu.edu.cn
Crosstalk of disulfidptosis-related subtypes identifying a prognostic signature to improve prognosis and immunotherapy r
taoka.rikiya@kagawa-u.ac.jp
Enfortumab vedotin promotes PD-L1 expression in urothelial carcinoma via NF-κB and STAT3 pathways highlighting mechanism
h.matsushita@aichi-cc.jp
Association between effector-type regulatory T cells and immune checkpoint expression on CD8+ T cells in malignant ascit
tiankangguo2019@163.com
Immune checkpoint blockade in the treatment of malignant tumor: current statue and future strategies.
hanymarei@mans.edu.eg
Cancer immunotherapy with immune checkpoint inhibitors (ICIs): potential, mechanisms of resistance, and strategies for r
xu.bei2@zs-hospital.sh.cn
Immunotherapy of thymic epithelial tumors: molecular understandings and clinical perspectives
Harriet.Kluger@yale.edu
A bedside to bench study of anti-PD-1, anti-CD40, and anti-CSF1R indicates that more is not necessarily better
maiselka@umd.edu
Plasmacytoid dendritic cells mediate CpG-ODN induced increase in survival in a mouse model of lymphangioleiomyomatosis.
mengliesu@xjtu.edu.cn
Musculoskeletal adverse events induced by immune checkpoint inhibitors: a large-scale pharmacovigilance study.
c.blank@nki.nl
Concomitant targeting of programmed death-1 (PD-1) and CD137 improves the efficacy of radiotherapy in a mouse model of h
patrycja.guzik@psi.ch
Promising potential of [177Lu]Lu-DOTA-folate to enhance tumor response to immunotherapy-a preclinical study using a syng
kamait@dokkyomed.ac.jp
Increased expression of adenosine 2A receptors in metastatic renal cell carcinoma is associated with poorer response to
juanita.lopez@icr.ac.uk
Combining DNA damaging therapeutics with immunotherapy: more haste, less speed.
asandler@childrensnational.org
PD-L1 checkpoint inhibition and anti-CTLA-4 whole tumor cell vaccination counter adaptive immune resistance: A mouse neu
changhua.ji2@pfizer.com
Inhibition of immune checkpoints PD-1, CTLA-4, and IDO1 coordinately induces immune-mediated liver injury in mice.
carina.hage@roche.com
Characterizing responsive and refractory orthotopic mouse models of hepatocellular carcinoma in cancer immunotherapy.
wada.teiji.fv@daiichisankyo.co.jp
[Fam-] trastuzumab deruxtecan (DS-8201a)-induced antitumor immunity is facilitated by the anti-CTLA-4 antibody in a mous
mmartins@med.miami.edu
Vaccine protection against rectal acquisition of SIVmac239 in rhesus macaques.
felix.herr@med.uni-muenchen.de
Contrast-enhanced ultrasound with VEGFR2-targeted microbubbles for monitoring combined anti-PD-L1/anti-CTLA-4 immunother
jtchen@jlu.edu.cn
Targeting immune checkpoints in malignant glioma.
inge.marie.svane@regionh.dk
Influence of ipilimumab on expanded tumour derived T cells from patients with metastatic melanoma.
luheshin@medimmune.com
Transformation of the tumour microenvironment by a CD40 agonist antibody correlates with improved responses to PD-L1 blo
raberj@ohsu.edu
Neuroinflammatory and cognitive consequences of combined radiation and immunotherapy in a novel preclinical model.
thomas.gruber@i-med.ac.at
Cblb-deficient T cells are less susceptible to PD-L1-mediated inhibition.
Mocikat@helmholtz-muenchen.de
Potent CD4+ T cell-associated antitumor memory responses induced by trifunctional bispecific antibodies in combination w
rxzhang@gdpu.edu.cn
Immune checkpoint inhibitors: breakthroughs in cancer treatment.
zhangyi02@xinhuamed.com.cn
Photodynamic Therapy Using RGD-Functionalized Quantum Dots Elicit a Potent Immune Response in a Syngeneic Mouse Model of
susu_mail@126.com
Clinical Significance and Molecular Annotation for PD-L1 Negative Advanced Non-Small Cell Lung Cancer with Sensitivity t
annamaria.digiacomo@unisi.it
From Co-Stimulation to Co-Inhibition: A Continuum of Immunotherapy Care Toward Long-Term Survival in Melanoma.
lawrence.fong@medicine.ucsf.edu.
Tumor-conditional anti-CTLA4 uncouples antitumor efficacy from immunotherapy-related toxicity.
j.g.borst@lumc.nl.
PD-1 or CTLA-4 blockade promotes CD86-driven Treg responses upon radiotherapy of lymphocyte-depleted cancer in mice.
dhodapkar@yale.edu
Early B cell changes predict autoimmunity following combination immune checkpoint blockade.
emeffre@stanford.edu.
CTLA-4 blockade shifts the B cell repertoire toward autoimmunity.
paul.walker@unige.ch.
Treating ICB-resistant glioma with anti-CD40 and mitotic spindle checkpoint controller BAL101553 (lisavanbulin).
masu@email.unc.edu.
Combination central tolerance and peripheral checkpoint blockade unleashes antimelanoma immunity.
darao@bwh.harvard.edu.
Pretreatment naive T cells are associated with severe irAE following PD-1/CTLA-4 checkpoint blockade for melanoma.
yumin_@126.com
The appropriate frequency and function of decidual Tim-3+CTLA-4+CD8+ T cells are important in maintaining normal pregnan
nikolaus.wagner@med.uni-tuebingen.de
S100B and LDH as early prognostic markers for response and overall survival in melanoma patients treated with anti-PD-1
simona.romano@unina.it
Alternative macrophage polarisation associated with resistance to anti-PD1 blockade is possibly supported by the splicin
Mark.Maurer@AlpineImmuneSciences.com
The engineered CD80 variant fusion therapeutic davoceticept combines checkpoint antagonism with conditional CD28 costimu
jlee@mdanderson.org
Genomic landscape associated with potential response to anti-CTLA-4 treatment in cancers.
xkliulang1314@163.com
Oncolytic peptide LTX-315 plus an anti-CTLA-4 antibody induces a synergistic anti-cancer immune response in residual tum
yzhang@ihv.umaryland.edu
Hijacking antibody-induced CTLA-4 lysosomal degradation for safer and more effective cancer immunotherapy.
hongguangxia@zju.edu.cn
Hsc70 promotes anti-tumor immunity by targeting PD-L1 for lysosomal degradation.
hongliu1014@csu.edu.cn
CD137L promotes immune surveillance in melanoma via HLTF regulation.
nathalie.chaput@gustaveroussy.fr
Systemic short chain fatty acids limit antitumor effect of CTLA-4 blockade in hosts with cancer.
daniel.hargboel.madsen@regionh.dk
β-adrenergic signaling blockade attenuates metastasis through activation of cytotoxic CD4 T cells.
ajtackett@uams.edu
Indicators of responsiveness to immune checkpoint inhibitors.
riki0716okita@yahoo.co.jp
Characterizing soluble immune checkpoint molecules and TGF-β1,2,3 in pleural effusion of malignant pleural mesothelioma.
ian.frew@uniklinik-freiburg.de
Characterisation of an autochthonous mouse ccRCC model of immune checkpoint inhibitor therapy resistance.
shlee119@skku.edu
Dissecting transcriptome signals of anti-PD-1 response in lung adenocarcinoma.
tazuma-tky@umin.ac.jp
Serum alanine aminotransferase as an early marker of outcomes in patients receiving anti-PD-1 or anti-CTLA-4 antibody.
Kevin.thierry@etu.univ-lyon1.fr
[Treg cell contribution to anti-CTLA-4 therapeutic effect].
ehenske@bwh.harvard.edu.
TSC2-deficient tumors have evidence of T cell exhaustion and respond to anti-PD-1/anti-CTLA-4 immunotherapy.
padsharma@mdanderson.org.
Modulation of EZH2 expression in T cells improves efficacy of anti-CTLA-4 therapy.
kroemer@orange.fr.
Ketogenic diet and ketone bodies enhance the anticancer effects of PD-1 blockade.
harriet.kluger@yale.edu.
Decoy-resistant IL-18 reshapes the tumor microenvironment and enhances rejection by anti-CTLA-4 in renal cell carcinoma.
zhaohang@jlu.edu.cn
Histone acetylation risk model predicts prognosis and guides therapy selection in glioblastoma: implications for chemoth
lauris.auch@gmail.com
Adverse drug events of immune checkpoint inhibitors - a retrospective, descriptive real-world data analysis.
jroszik@mdanderson.org
Novel algorithmic approach predicts tumor mutation load and correlates with immunotherapy clinical outcomes using a defi
john.tentler@cuanschutz.edu
RX-5902, a novel β-catenin modulator, potentiates the efficacy of immune checkpoint inhibitors in preclinical models of
wangfeng16@sjtu.edu.cn
The role of T cell trafficking in CTLA-4 blockade-induced gut immunopathology.
xiangyq@sysucc.org.cn
Efficacy and safety of cadonilimab (PD-1/CTLA-4 bispecific) in combination with chemotherapy in anti-PD-1-resistant recu
s.kiaie@renap.ir
Nano-immunotherapy: overcoming delivery challenge of immune checkpoint therapy.
JWeidhaas@mednet.ucla.edu
Germline microRNA-based signatures predict toxicity and response to anti-CTLA-4 therapy.
kyra.mccarty@duke.edu
Use of PULSAR (personalized ultra-fractionated stereotactic adaptive radiotherapy) as consolidation with immune checkpoi
macharya@uci.edu
Immune checkpoint inhibition perturbs neuro-immune homeostasis and impairs cognitive function.
kbarakat@ualberta.ca
Targeting cytotoxic lymphocyte antigen 4 (CTLA-4) in breast cancer.
angelo.paci@gustaveroussy.fr
Immune checkpoint-targeted antibodies: a room for dose and schedule optimization?
ivan.pourmir@aphp.fr
Soluble TIM-3, likely produced by myeloid cells, predicts resistance to immune checkpoint inhibitors in metastatic clear
lnorian@uab.edu
Therapeutic Time-restricted Feeding Reduces Renal Tumor Bioluminescence in Mice but Fails to Improve Anti-CTLA-4 Efficac
h_saijo@h-keiaikai.or.jp
Anti-CTLA-4 Antibody Might Be Effective Against Non-small Cell Lung Cancer With Large Size Tumor.
k.s.rallis@smd16.qmul.ac.uk
T-cell-based Immunotherapies for Haematological Cancers, Part A: A SWOT Analysis of Immune Checkpoint Inhibitors (ICIs)
ivoutsadakis@nosm.ca
Immune Blockade Inhibition in Breast Cancer.
gabriel.surdacki@wp.pl
The role of immune checkpoint inhibitors in prostate cancer.
octavian.bucur@ivb.ro
Thyroid-related adverse events induced by immune checkpoint inhibitors.
n.maurea@istitutotumori.na.it
Immune checkpoint inhibitor therapy increases systemic SDF-1, cardiac DAMPs Fibronectin-EDA, S100/Calgranulin, galectine
hejia63@yeah.net
Metabolic and Nutritional Disorders Following the Administration of Immune Checkpoint Inhibitors: A Pharmacovigilance St
Apatel11@mdanderson.org
Mucocutaneous adverse events to immune checkpoint inhibitors.
s.m.vanderleij@umcutrecht.nl
Differences in checkpoint-inhibitor-induced hypophysitis: mono- versus combination therapy induced hypophysitis.
ms.vd.heijden@nki.nl
The Tumor Immune Landscape and Architecture of Tertiary Lymphoid Structures in Urothelial Cancer.
PeiPei.Chong@taylors.edu.my
Editorial: Differential Efficacy of Immune Checkpoint Inhibitors due to Age and Sex Factors.
giuseppe.bronte@irst.emr.it
Case Report: Circulating Myeloid-Derived Suppressive-Like Cells and Exhausted Immune Cells in Non-Small Cell Lung Cancer
jack_elias@brown.edu
CHI3L1 enhances melanoma lung metastasis via regulation of T cell co-stimulators and CTLA-4/B7 axis.
rouzeh.korangy@nih.gov
Checkpoint Inhibitors Modulate Plasticity of Innate Lymphoid Cells in Peripheral Blood of Patients With Hepatocellular C
Tanja.Fetter@ukbonn.de
Severe autoimmune hemolytic anemia following immunotherapy with checkpoint inhibitors in two patients with metastatic me
simon.dovedi@astrazeneca.com
Impact of CTLA-4 checkpoint antibodies on ligand binding and Transendocytosis.
m.guida@oncologico.bari.it
Case report: Is severe toxicity the price to pay for high sensitivity to checkpoint inhibitors immunotherapy in desmopla
zhengmin@sysucc.org.cn
The comparison of efficacy and safety between cadonilimab (PD-1/CTLA-4) and anti-PD-1 inhibitors in patients with recurr
marek.wojtukiewicz@umb.edu.pl
Inhibitors of immune checkpoints-PD-1, PD-L1, CTLA-4-new opportunities for cancer patients and a new challenge for inter
zhaoailin@wchscu.cn
Dual blockade immunotherapy targeting PD-1/PD-L1 and CTLA-4 in lung cancer.
dsshin@mednet.ucla.edu
Key Players of the Immunosuppressive Tumor Microenvironment and Emerging Therapeutic Strategies.
lina6678@163.com
Beyond monotherapy: multimodal strategies integrating immune checkpoint inhibitors in lymphoma management.
amtsumura@ucdavis.edu
Checkpoint inhibition in hematologic malignancies.
jgolay@fondazionefrom.it
Combined Anti-Cancer Strategies Based on Anti-Checkpoint Inhibitor Antibodies.
mdeligiorgi@yahoo.com
The Continuum of Thyroid Disorders Related to Immune Checkpoint Inhibitors: Still Many Pending Queries.
mbros@uni-mainz.de
Immunomodulatory Properties of Immune Checkpoint Inhibitors-More than Boosting T-Cell Responses?
p.altevogt@dkfz.de
Modern Aspects of Immunotherapy with Checkpoint Inhibitors in Melanoma.
ondrej.kodet@lf1.cuni.cz
The Abscopal Effect in the Era of Checkpoint Inhibitors.
fabiomorandi@gaslini.org
HLA-G and Other Immune Checkpoint Molecules as Targets for Novel Combined Immunotherapies.
carlos.hernandez.saez@navarra.es
Systemic Blood Immune Cell Populations as Biomarkers for the Outcome of Immune Checkpoint Inhibitor Therapies.
mazorr@Medimmune.com
SS1P Immunotoxin Induces Markers of Immunogenic Cell Death and Enhances the Effect of the CTLA-4 Blockade in AE17M Mouse
tommaso.tartaglione@unicatt.it
Molecular and Genetic Immune Biomarkers of Primary and Immune-Therapy Induced Hypophysitis: From Laboratories to the Cli
rohulla.vaseq@ukbonn.de
Revising the Landscape of Cytokine-Induced Killer Cell Therapy in Lung Cancer: Focus on Immune Checkpoint Inhibitors.
jacek.glajzer@uk-erlangen.de
Investigation of the CTLA-4-CD28 Axis in Oral Squamous Cell Carcinoma.
f.huemer@salk.at
miRNA-Based Therapeutics in the Era of Immune-Checkpoint Inhibitors.
marcin.schmidt@up.poznan.pl
The Tumor and Host Immune Signature, and the Gut Microbiota as Predictive Biomarkers for Immune Checkpoint Inhibitor Res
lfwang_2@sina.com
Targeting CD47 Enhances the Efficacy of Anti-PD-1 and CTLA-4 in an Esophageal Squamous Cell Cancer Preclinical Model.
sjha@yonsei.ac.kr
Immune Checkpoint Inhibitors in 10 Years: Contribution of Basic Research and Clinical Application in Cancer Immunotherap
jmackiewicz@biocontract.com
Programmed cell death 1 checkpoint inhibitors in the treatment of patients with advanced melanoma.
tiborbakacs@gmail.com
Complete Remission of Vocal Cord Cancer Treated With Low-Dose Ipilimumab Plus Nivolumab Combined With Interleukin-2 and
liuzimin301@126.com
Combination of cadonilimab (PD-1/CTLA-4 bispecific antibody) and apatinib as salvage therapy achieves partial response i
ronald.anderson@up.ac.za
Immune Dysregulation in Cancer Patients Undergoing Immune Checkpoint Inhibitor Treatment and Potential Predictive Strate
katrin.goepfert@unimedizin-mainz.de
Rational Combination of Parvovirus H1 With CTLA-4 and PD-1 Checkpoint Inhibitors Dampens the Tumor Induced Immune Silenc
johanna.matull@uk-essen.de
Durable Complete Response in a Melanoma Patient With Unknown Primary, Associated With Sequential and Severe Multi-Organ
mar.christodoulou@euc.ac.cy
Editorial: Immune-checkpoint inhibitors in anti-cancer armamentarium: a double-edged sword in risk of developing autoimm
euiho.kim@ip-korea.org
Mechanisms underlying response and resistance to immune checkpoint blockade in cancer immunotherapy.
zhaobin@pumch.cn
Immune Checkpoint Inhibitor-Associated Tumor Lysis Syndrome: A Real-World Pharmacovigilance Study.
wuxinan@boe.com.cn
Cardiac arrhythmias associated with immune checkpoint inhibitors: A comprehensive disproportionality analysis of the FDA
w.c.f.w.meijers@umcg.nl
The role of immune checkpoints in cardiovascular disease.
youruxu2008@163.com
Hepatitis-related adverse events associated with immune checkpoint inhibitors in cancer patients: an observational, retr
bertrand.routy@umontreal.ca
Tumor Infiltrating Lymphocytes Signature as a New Pan-Cancer Predictive Biomarker of Anti PD-1/PD-L1 Efficacy.
mehmet.a.bilen@emory.edu
Inflammatory Markers in Cancer Immunotherapy.
yanluo2018@cqu.edu.cn
Delayed immune-related adverse events profile associated with immune checkpoint inhibitors: a real-world analysis.
julie.vackova@natur.cuni.cz
CD80 Expression on Tumor Cells Alters Tumor Microenvironment and Efficacy of Cancer Immunotherapy by CTLA-4 Blockade.
wturbitt@uab.edu
Diet-Induced Obesity Impairs Outcomes and Induces Multi-Factorial Deficiencies in Effector T Cell Responses Following An
chu.peiyi@msa.hinet.net
Cure the Incurable? Recent Breakthroughs in Immune Checkpoint Blockade for Hepatocellular Carcinoma.
s.said@qu.edu.qa
Breaking Barriers: The Promise and Challenges of Immune Checkpoint Inhibitors in Triple-Negative Breast Cancer.
tuba.gide@sydney.edu.au
Clinical and Molecular Heterogeneity in Patients with Innate Resistance to Anti-PD-1 +/- Anti-CTLA-4 Immunotherapy in Me
chuzhh@mail.sysu.edu.cn
Expression Pattern and Prognostic Value of CTLA-4, CD86, and Tumor-Infiltrating Lymphocytes in Rectal Cancer after Neoad
a.khammari@chu-caen.fr
Severe Late-Onset Grade III-IV Adverse Events under Immunotherapy: A Retrospective Study of 79 Cases.
mhong32@uwo.ca
Addressing the Elephant in the Immunotherapy Room: Effector T-Cell Priming versus Depletion of Regulatory T-Cells by Ant
snawrocki@arizona.edu
Current Landscape of Immune Checkpoint Inhibitors for Metastatic Urothelial Carcinoma: Is There a Role for Additional T-
patel069@umn.edu
Success of Checkpoint Blockade Paves the Way for Novel Immune Therapy in Malignant Pleural Mesothelioma.
nathan.holland@ttuhsc.edu
The Heart of the Matter: Immune Checkpoint Inhibitors and Immune-Related Adverse Events on the Cardiovascular System.
marine.valery@gustaveroussy.fr
Immunotherapy and Hepatocellular Cancer: Where Are We Now?
rodrigohorta@ufmg.br
Checkpoint Inhibitors in Dogs: Are We There Yet?
patrizia.farci@nih.gov
Identification of Two Distinct Immune Subtypes in Hepatitis B Virus (HBV)-Associated Hepatocellular Carcinoma (HCC).
alicja.walewska@umb.edu.pl
Effects of Combinatory In Vitro Treatment with Immune Checkpoint Inhibitors and Cytarabine on the Anti-Cancer Immune Mic
sara-liss@wp.pl
Current Treatment of Melanoma Brain Metastases.
cdsmith@apogee-biotech.com
Opaganib Downregulates N-Myc Expression and Suppresses In Vitro and In Vivo Growth of Neuroblastoma Cells.
gloria.mittica@ircc.it
Immune Checkpoint Inhibitors: A New Opportunity in the Treatment of Ovarian Cancer?
yyang9@mdanderson.org
CD103+ cDC1 Dendritic Cell Vaccine Therapy for Osteosarcoma Lung Metastases.
pshariatpanahi@ut.ac.ir
Distinct Dynamics of Migratory Response to PD-1 and CTLA-4 Blockade Reveals New Mechanistic Insights for Potential T-Cel
nour.alsaleh@students.kasralainy.edu.eg
Immune Checkpoint Molecules in Hodgkin Lymphoma and Other Hematological Malignancies.
yujiang.fang@dmu.edu
From Bench to Bladder: The Rise in Immune Checkpoint Inhibition in the Treatment of Non-Muscle Invasive Bladder Cancer.
dawid.groth@umb.edu.pl
Differential Response of MDA-MB-231 and MCF-7 Breast Cancer Cells to In Vitro Inhibition with CTLA-4 and PD-1 through Ca
aharui@mednet.ucla.edu
Hyaluronidase Enhances Targeting of Hydrogel-Encapsulated Anti-CTLA-4 to Tumor Draining Lymph Nodes and Improves Anti-Tu
spadaro@unina.it
Innate Immune Modulation by GM-CSF and IL-3 in Health and Disease.
tfujimura1@med.tohoku.ac.jp
Immunotherapy for Melanoma: The Significance of Immune Checkpoint Inhibitors for the Treatment of Advanced Melanoma.
alessandro.antonelli@med.unipi.it
Autoimmune Endocrine Dysfunctions Associated with Cancer Immunotherapies.
julian.schardt@insel.ch
[The use of immune checkpoint inhibitors in routine oncology].
jlysaght@tcd.ie
Nutrient deprivation and hypoxia alter T cell immune checkpoint expression: potential impact for immunotherapy.
david.pinato@imperial.ac.uk
Immunotherapy in Hepatocellular Carcinoma.
gerlig.widmann@i-med.ac.at
Imaging Features of Toxicities by Immune Checkpoint Inhibitors in Cancer Therapy.
mariagrazia.castagna@unisi.it
Baseline serum TSH levels predict the absence of thyroid dysfunction in cancer patients treated with immunotherapy.
ligd@zzu.edu.cn
A Novel CTLA-4 affinity peptide for cancer immunotherapy by increasing the integrin αvβ3 targeting.
yings@zju.edu.cn
ARIH1 signaling promotes anti-tumor immunity by targeting PD-L1 for proteasomal degradation.
yangxinfu@tsinghua.edu.cn
A next-generation anti-CTLA-4 probody mitigates toxicity and enhances anti-tumor immunity in mice.
kristina.young@providence.org
Optimizing Timing of Immunotherapy Improves Control of Tumors by Hypofractionated Radiation Therapy.