Chemical Strategies With Documented Efficacy For P

A Reversible Protecting Group for the Amide Bond in Peptides. Use in the Synthesis of ′Difficult Sequences′.

T. Johnson; M. Quibell; D. Owen et al.

N-terminal engineering of amyloid-β-binding Affibody molecules yields improved chemical synthesis and higher binding aff

Lindgren, Joel; Wahlström, Anna; Danielsson, Jens et al.

Synthesis of of beta-amyloid precursor peptide and presenilin segments.

Baláspiri, L; Langel, U

Depsipeptide methodology for solid-phase peptide synthesis: circumventing side reactions and development of an automated

Coin, Irene; Dölling, Rudolf; Krause, Eberhard et al.

Combining a polar resin and a pseudo‐proline to optimize the solid‐phase synthesis of a ‘difficult sequence’

G. Cremer; Hanane Tariq; A. Delmas

Investigation of crudes of synthesis of [Leu31, Pro34]-neuropeptide Y by capillary zone electrophoresis/mass spectrometr

Zaramella, A; Curcuruto, O; Hamdan, M et al.

Using a sterically restrictive amino acid as a 19F NMR label to monitor and to control peptide aggregation in membranes.

Wadhwani, Parvesh; Bürck, Jochen; Strandberg, Erik et al.

Sequence-assisted peptide synthesis (SAPS).

Due Larsen, B; Holm, A

Sequence-independent control of peptide conformation in liposomal vaccines for targeting protein misfolding diseases.

Hickman, David T; López-Deber, María Pilar; Ndao, Dorin Mlaki et al.

Synthesis of Abeta[1-42] and its derivatives with improved efficiency.

Zarándi, Márta; Soós, Katalin; Fülöp, Lívia et al.

Synthesis of disubstituted amino acids and peptide inhibitors of amyloid beta aggregation

G. McCandless

Difficult sequence含有ペプチド合成における新規“O-アシルイソペプチド法”の開発：O–N分子内アシル転位反応によるアミロイドベータペプチド(Aβ)1-42の合成

洋平 相馬; 良雄 林; 陽介 千代森 et al.

A New Generation of Reversible Backbone‐Amide Protection for the Solid Phase Synthesis of Difficult Sequences.

John Howe; M. Quibell; T. Johnson

An efficient solid-phase strategy for the construction of chemokines.

McNamara, J F; Lombardo, H; Pillai, S K et al.

The synthesis and spectroscopic analysis of the neurotoxic prion peptide 106-126: Comparative use of manual Boc and Fmoc

M. Jobling; C. Barrow; A. White et al.

O-Allyl protection in the Fmoc-based synthesis of difficult PNA.

Altenbrunn, Frank; Seitz, Oliver

Solid-phase peptide synthesis: from standard procedures to the synthesis of difficult sequences.

Coin, Irene; Beyermann, Michael; Bienert, Michael

A Novel Method for the Synthesis of Difficult Sequence-Containing Peptides via O-Acyl Isopeptides : The Use of O-N Intra

Youhei Sohma; M. Sasaki; Tooru Kimura et al.

Chemistry of alpha-hydroxymethylserine: problems and solutions.

Stasiak, Marcin; Słomczyńska, Urszula; Olma, Aleksandra et al.

‘O-Acyl isopeptide method’ for the efficient synthesis of difficult sequence-containing peptides: use of ‘O-acyl isodipe

Youhei Sohma; A. Taniguchi; M. Skwarczynski et al.

“Difficult Sequences” and Solvation of Peptide Chains in Solid-Phase Peptide Synthesis

M. Narita; Shôkichi Ôuchi

Solid phase synthesis of hydrophobic difficult sequence peptides on BDDMA‐PS support

P. K. Ajikumar; K. Devaky

Some 'difficult sequences' made easy. A study of interchain association in solid-phase peptide synthesis.

Hyde, C; Johnson, T; Owen, D et al.

'Click peptide': a novel 'O-acyl isopeptide method' for peptide synthesis and chemical biology-orien

Sohma, Youhei; Taniguchi, Atsuhiko; Yoshiya, Taku et al.

Aggregation of resin-bound peptides during solid-phase peptide synthesis. Prediction of difficult sequences.

Krchnák, V; Flegelová, Z; Vágner, J

Lytic peptides with improved stability and selectivity designed for cancer treatment.

Chen, Long; Tu, Zhigang; Voloshchuk, Natalya et al.

Use of Fmoc-N-(2-hydroxy-4-methoxybenzyl)amino acids in peptide synthesis.

Zeng, W; Regamey, P O; Rose, K et al.

An improved solid-phase synthesis of a difficult-sequence peptide using hexafluoro-2-propanol.

S. Milton; R. C. Milton

Syntheses of Difficult Hydrophobic Sequences Using 2-(4-Nitrophenyl)sulfonylethoxycarbonyl(Nsc)-N α-(2-hydroxy- 4-methox

H. J. Lee; W. Chweh; Young-Deug Kim et al.

Special Issue – Tribute to Bruce Merrifield

S. Kent; P. Alewood

An Efficient Approach for the Synthesis of Salmon Calcitonin Using Oxazolidine Dipeptides

W. Chweh; H. J. Lee; Young-Deug Kim et al.

Recent progress in the improvement of the coupling efficiency of "difficult sequences" in peptide synthesis.

Han, Xiang; Wang, De-xin

The depsipeptide method for solid-phase synthesis of difficult peptides.

Coin, Irene

Optimization of solid-phase synthesis of difficult peptide sequences via comparison between different improved approache

Abdel Rahman, S; El-Kafrawy, A; Hattaba, A et al.

A new detector for fully automatic peptide synthesis.

Fox, J E; Newton, R; Stroud, C H

Development of a coarse-grained protein model and molecular dyanmics studies of amyloid-[beta] peptide aggregation

Wei Han

Use of the Hmb backbone-protecting group in the synthesis of difficult sequences.

Simmonds, R G

N,O-bisFmoc derivatives of N-(2-hydroxy-4-methoxybenzyl)-amino acids: useful intermediates in peptide synthesis.

Johnson, T; Quibell, M; Sheppard, R C

High‐yield, solid‐phase synthesis of humanin, an Alzheimer's disease associated, novel 24‐mer peptide which contain

A. Evangelou; C. Zikos; E. Livaniou et al.

Pseudo-prolines (psi Pro) for accessing "inaccessible" peptides.

Mutter, M; Nefzi, A; Sato, T et al.

Organic Chemistry and Medicinal Chemistry Based on α‐Hydroxy‐β‐Amino Acids

Y. Hayashi; Y. Kiso

Amino acid structure and "difficult sequences" in solid phase peptide synthesis.

Bedford, J; Hyde, C; Johnson, T et al.

Solid-phase synthesis of the lipopeptide Myr-HBVpreS/2-78, a hepatitis B virus entry inhibitor.

Schieck, Alexa; Müller, Thomas; Schulze, Andreas et al.

Improving Internal Peptide Dynamics in the Coarse-Grained MARTINI Model: Toward Large-Scale Simulations of Amyloid- and

Seo, Mikyung; Rauscher, Sarah; Pomès, Régis et al.

Microwave-assisted synthesis of difficult sequence-containing peptides using the isopeptide method.

W. Hussein; Tzu-yu Liu; I. Toth et al.

Design strategies for anti-amyloid agents.

Mason, Jody M; Kokkoni, Nicoleta; Stott, Kelvin et al.

SPPS of difficult sequences. A comparison of chemical conditions, synthetic strategies and on-line monitoring.

Dettin, M; Pegoraro, S; Rovero, P et al.

Reverse-phase HPLC of the hydrophobic pulmonary surfactant proteins: detection of a surfactant protein C isoform contain

Gustafsson, M; Curstedt, T; Jörnvall, H et al.

Amyloid beta-peptide aggregation. What does it result in and how can it be prevented?

Nerelius, Charlotte; Johansson, Jan; Sandegren, Anna

Chemical synthesis and biological evaluation of an antimicrobial peptide gonococcal growth inhibitor.

Wade, John D; Lin, Feng; Hossain, Mohammed Akhter et al.

Difficult Peptides

Miranda, Maria Terêsa Machini de; Liria, Cleber Wanderlei; Remuzgo, César

A Reversible Protecting Group for the Amide Bond in Peptides. Use in the Synthesis of ′Difficult Sequences′.

T. Johnson; M. Quibell; D. Owen et al.

S-acyl isopeptide method: use of allyl-type protective group for improved preparation of thioester-containing S-acyl iso

Yoshiya, Taku; Hasegawa, Yuka; Kawamura, Wakana et al.

Application of the O-N intramolecular acyl migration reaction in medicinal chemistry.

Skwarczynski, Mariusz; Kiso, Yoshiaki

Amino acid bromides: their N-protection and use in the synthesis of peptides with extremely difficult sequences.

DalPozzo, Alma; Ni, Minghong; Muzi, Laura et al.

O-アシルイソペプチド法を基盤とした“Click Peptide” の開発:アルツハイマー病に関連するdifficult sequence含有Aβ1-42変異体の合成

洋平 相馬; 陽介 千代森; 敦彦 谷口 et al.

Fourier Transform Infrared Spectroscopic Studies of Peptides: Potentials and Pitfalls

Haris, Parvez I.

新規 S-アシルイソペプチド法を用いた difficult sequence 含有ペプチドの効率的合成

縫 伊藤; 拓 吉矢; 徹子 木村 et al.

Ethyl 2-cyano-2-(2-nitrobenzenesulfonyloxyimino)acetate (o-NosylOXY): a recyclable coupling reagent for racemization-fre

Dev, Dharm; Palakurthy, Nani Babu; Thalluri, Kishore et al.

Novel and efficient synthesis of difficult sequence-containing peptides through O-N intramolecular acyl migration reacti

Youhei Sohma; M. Sasaki; Y. Hayashi et al.

Peptidomimetics based on ring-fused 2-pyridones : probing pilicide function in uropathogenic E. coli and identification

V. Åberg

Microwave-Assisted Solid-Phase Synthesis of Pseudopeptide Containing Reduced Amide Bond

Mi-Sun Park; Shim Hyeung-Soo; Cho Won-Mi et al.

Comparative syntheses of peptides and peptide thioesters derived from mouse and human prion proteins.

Sebestík, Jaroslav; Zawada, Zbigniew; Safařík, Martin et al.

Amyloid-beta as a "difficult sequence" in solid phase peptide synthesis.

A. Tickler; A. Clippingdale; J. Wade

Development of O-acyl isopeptide method.

Youhei Sohma; Taku Yoshiya; A. Taniguchi et al.

Synthesis of oligopeptides through O-acyl isopeptide method.

H. S. Lalithamba; H. Hemantha; V. Sureshbabu

Recent progress in the improvement of the coupling efficiency of "difficult sequences" in peptide synthesis.

Han, Xiang; Wang, De-xin

"O-Acyl Isopeptide Method" for the Synthesis of Difficult Sequence-Containing Peptides : Application to the Sy

Youhei Sohma; Y. Hayashi; Yousuke Chiyomori et al.

Synthesis of humanin and its derivatives to treat traumatic brain injury in mice

David Meridor

Amyloidogenic peptides for design of inhibitors of peptide aggregation and as templates for new bionanomaterials

R. Elgersma

Peptide synthesis on chitin.

Neugebauer, W; Williams, R E; Barbier, J R et al.

A New Generation of Reversible Backbone‐Amide Protection for the Solid Phase Synthesis of Difficult Sequences.

John Howe; M. Quibell; T. Johnson

Aqueous microwave-assisted solid-phase peptide synthesis using Fmoc strategy: in-water synthesis of "difficult sequ

Hojo, Keiko; Ichikawa, Hideki; Hara, Asaki et al.

Synthesis of ‘difficult’ peptide sequences: application of a depsipeptide technique to the Jung–Redemann 10- and 26-mers

L. A. Carpino; E. Krause; C. D. Sferdean et al.

Difficult couplings in stepwise solid phase peptide synthesis: predictable or just a guess?

van Woerkom, W J; van Nispen, J W

Facile synthesis of alpha,alpha-diisobutylglycine and anchoring its derivatives onto PAL-PEG-PS resin.

Yanwen Fu; M. Etienne; R. Hammer

Improved preparation of amyloid-beta peptides using DBU as Nalpha-Fmoc deprotection reagent.

Tickler, A K; Barrow, C J; Wade, J D

The ‘O‐acyl isopeptide method’ for the synthesis of difficult sequence‐containing peptides: application to the synthesis

Youhei Sohma; Y. Hayashi; Maiko Kimura et al.

Reversal of aggregation using β-breaker dipeptide containing peptides: Application to Aβ(1-40) self-assembly and its inh

Nadimpally, Krishna Chaitanya; Paul, Ashim; Mandal, Bhubaneswar

Peptidosteroid tweezers revisited: DNA binding through an optimised design

L. Carrette; T. Morii; A. Madder

Three Decades of Amyloid Beta Synthesis: Challenges and Advances

Kasim, Johanes K.; Kavianinia, Iman; Harris, Paul W. R. et al.

Recent Progress in the Chemical Synthesis of Class II and S-Glycosylated Bacteriocins

Bédard, François; Biron, Éric

Corrin Ring Modification in Peptide Drug Development - a Brief History of "Corrination".

Cham, Nancy; Doyle, Robert P

Challenges and Perspectives in Chemical Synthesis of Highly Hydrophobic Peptides.

Mueller, Lena K; Baumruck, Andreas C; Zhdanova, Hanna et al.