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A Simple Method to Reduce both Lactic Acid and Ammonium Production in Industrial Animal Cell Culture
Impact of fluidic agitation on human pluripotent stem cells in stirred suspension culture.
The effect of supplementing pony diets with yeast on 2. The faecal microbiome.
Enhanced recombinant factor VII expression in Chinese hamster ovary cells by optimizing signal peptides and fed-batch me
Optimal design of dynamic experiments for scalar-on-function linear models with application to a biopharmaceutical study
Selection of chemically defined media for CHO cell fed-batch culture processes.
High cysteine concentrations in cell culture media lead to oxidative stress and reduced bioprocess performance of recomb
Modular development enables rapid design of media for alternative hosts
Dietary supplementation of selenium nanoparticle improves the vitellogenesis and fecundity of female zebrafish.
Influences of Short-Term Fasting and Carbohydrate Supplementation on Gut Immunity and Mucosal Morphology in Mice.
Purification and Analytics of a Monoclonal Antibody from Chinese Hamster Ovary Cells Using an Automated Microbioreactor
Oleanolic Acid Regulates Intestinal Cell Proliferation and Protein Synthesis Capacity in Piglets via the Bile Acid-TGR5/
Using MVDA with Stoichiometric Balances to Optimize Amino Acid Concentrations in Chemically Defined CHO Cell Culture Med
Leucine supplementation at the onset of high-fat feeding does not prevent weight gain or improve glycemic regulation in
Cysteine Attenuates Intestinal Inflammation by Regulating the Gut Microbiota and TLR4-JNK/MAPK-NF-κB Pathway in Piglets
Rapid development of clone-specific, high-performing perfusion media from established feed supplements.
Iron supplementation in the diets of hybrid catfish (Ictalurus punctatus × I. furcatus) juveniles affected haematocrit l
Cottonseed hydrolysate supplementation alters metabolic and proteomics responses in Chinese hamster ovary cell cultures
Rosmarinic acid enhances CHO cell productivity and proliferation through activation of the unfolded protein response and
Insight into the roles of tyrosine on rCHO cell performance in fed-batch cultures.
Secondary feed filtration and storage conditions influence trace element availability and process performance at 2000 L
Utilization of Cottonseed Meal Protein Hydrolysate by Crustaceans: Insights on Growth Performance, Protein Turnover, and
3 Modulation of glycolysis alters histone acetylation and gene expression in bovine blastocysts produced invitro
Effects of Tyrosine and Tryptophan in Rats with Diet-Induced Obesity
A comparative analysis of recombinant Fab and full‐length antibody production in Chinese hamster ovary cells
Uncovering new poloxamer attributes significantly impacting mammalian cell growth performance
Autophagy-inducing peptide increases CHO cell monoclonal antibody production in batch and fed-batch cultures.
Administration of EPA improves lipopolysaccharide-induced intestinal dysfunction in turbot (Scophthalmus maximus L.) thr
Nitrogen supplementation ameliorates product quality and quantity during high cell density bioreactor studies of Pichia
Increased MSX level improves biological productivity and production stability in multiple recombinant GS CHO cell lines
Identification of novel inhibitory metabolites and impact verification on growth and protein synthesis in mammalian cell
Dietary Supplementation of a Mixture of Nucleotides, β-Glucan and Vitamins C and E Improved the Growth and Health Perfor
Exploitation of the ribosomal protein L10 R98S mutation to enhance recombinant protein production in mammalian cells
EGCG improves recombinant protein productivity in Chinese hamster ovary cell cultures via cell proliferation control
N-Glycosylation modulators for targeted manipulation of glycosylation for monoclonal antibodies.
Protective effects of dietary icariin on lipopolysaccharide-induced acute oxidative stress and hepatopancreas injury in
Effects of cysteine, asparagine, or glutamine limitations in Chinese hamster ovary cell batch and fed-batch cultures.
A statistical approach to improve compound screening in cell culture media.
Effects of dietary deoiled soy lecithin supplementation on milk production and fatty acid digestibility in Holstein dair
Effect of different cell culture media on the production and glycosylation of a monoclonal antibody from a CHO cell line
Metabolic engineering of CHO cells to prepare glycoproteins.
Deciphering Metabolic Pathways in High-Seeding-Density Fed-Batch Processes for Monoclonal Antibody Production: A Computa
Methionine metabolism and the effectiveness of its use as a feed additive
Analysis of Transformed Upstream Bioprocess Data Provides Insights into Biological System Variation.
Process‐induced cell cycle oscillations in CHO cultures: Online monitoring and model‐based investigation
Oxidative stress‐alleviating strategies to improve recombinant protein production in CHO cells
4-(2,5-Dimethyl-1H-pyrrol-1-yl)-N-(2,5-dioxopyrrolidin-1-yl) benzamide improves monoclonal antibody production in a Chin
Effects of pyruvate on primary metabolism and product quality for a high-density perfusion process.
Engineering Oxidative Stress Resistance in CHO Cell Factories
Comprehensive stable-isotope tracing of glucose and amino acids identifies metabolic by-products and their sources in CH
A rapid, simple and sensitive microfluidic chip electrophoresis mass spectrometry method for monitoring amino acids in c
Process development for an inducible rituximab-expressing Chinese hamster ovary cell line.
Application of a curated genome-scale metabolic model of CHO DG44 to an industrial fed-batch process.
Dietary L-Lysine Requirement of Coho Salmon (Oncorhynchus kisutch) Alevins
- **DOI:** 10.25687/1996-6733.prodanimbiol.2018.3.65-74 - **Authors:** Макар З.Н., Черепанов Г.Г. - **Year:** 2018 - **J
Studies to Prevent Degradation of Recombinant Fc-Fusion Protein Expressed in Mammalian Cell Line and Protein Characteriz
Kinetic modeling of Chinese hamster ovary cell culture: factors and principles.
Effect of dietary N-carbamylglutamate on development of ovarian follicles via enhanced angiogenesis in the chicken.
Recent advances in culture medium design for enhanced production of monoclonal antibodies in CHO cells: A comparative st
Development of a chemically defined platform fed-batch culture media for monoclonal antibody-producing CHO cell lines wi
The study of ameliorative effect of dietary supplementation of vitamin C, vitamin E, and tryptophan on Labeo rohita (Cyp
Combination of histidine, lysine, methionine, and leucine promotes β-casein synthesis via the mechanistic target of rapa
Effects of Glutamine Supplementation on Atlantic Salmon Salmo salar Metabolic Performance at High Temperatures.
Enhancing CHO cell productivity through a dual selection system using Aspg and Gs in glutamine free medium.
Modulation of nutrient precursors for controlling metabolic inhibitors by genome-scale flux balance analysis.
Computer-Aided Strategies for Determining the Amino Acid Composition of Medium for Chinese Hamster Ovary Cell-Based Biom
Exploring metabolic effects of dipeptide feed media on CHO cell cultures by in silico model-guided flux analysis.
Dietary taurine modulates hepatic oxidative status, ER stress and inflammation in juvenile turbot (Scophthalmus maximus
Amino acid supplementation for enhancing recombinant protein production in E. coli.
Effect of N-acetyl cysteine and glycine supplementation on growth performance, glutathione synthesis, anti-oxidative and
Translational landscape and protein biogenesis demands of the early secretory pathway in Komagataella phaffii
Cell culture media for recombinant protein expression in Chinese hamster ovary (CHO) cells: History, key components, and
48 The impact of leucine supplementation in milk replacer on muscle proteome and metabolism in neonatal dairy calves
Feeding strategy impacts heterologous protein production in Yarrowia lipolytica fed-batch cultures-Insight into the role
Methionine and valine activate the mammalian target of rapamycin complex 1 pathway through heterodimeric amino acid tast
Development of a chemically defined platform fed-batch culture media for monoclonal antibody-producing CHO cell lines wi
Performance and Milk Composition of Nubian Goats as Affected by Increasing Level of Nannochloropsis oculata Microalgae.
Feedback control of two supplemental feeds during fed-batch culture on a platform process using inline Raman models for
Effects of encapsulated cinnamaldehyde on growth performance, intestinal digestive and absorptive functions, meat qualit
Use of novel cystine analogs to decrease oxidative stress and control product quality.
Correlation and Predictive Modeling of Extracellular Cell Culture Metabolites to Drug Product Titer and Cellular Viabili
Beyond tyrosine feeding: A novel fed-batch cultivation strategy based on tyrosine metabolic engineering in recombinant C
Automated Raman feed-back control of multiple supplemental feeds to enable an intensified high inoculation density fed-b
Metabolic Network Modelling of Chinese Hamster Ovary (CHO) Culture Bioreactors Operated as Microbial Cell Factories
Nutrient-sensing kinase signaling in bovine immune cells is altered during the postpartum nutrient deficit: A possible r
Dietary Histidine, Threonine, or Taurine Supplementation Affects Gilthead Seabream (Sparus aurata) Immune Status.
Dietary propylene glycol mitigates cold stress and improves physio-metabolic responses in Pangasianodon hypophthalmus (S
Potential Applications of Yeast Biomass Derived from Small-Scale Breweries
Modulation of nutrient precursors for controlling metabolic inhibitors by genome-scale flux balance analysis.
Stress-induced increase of monoclonal antibody production in CHO cells.
Improved cultivation of Chinese hamster ovary cells in bioreactor with reciprocal mixing.
Dietary supplementation with lysine (protein) in late pregnancy does not enhance mammary development in multiparous sows
Role of lipoic acid (Thioctic acid) in improving vitality of different tissue culture cells
Supplementation Strategies for Tuning Glycosylation of Monoclonal Antibodies and Enhancing Growth in Mammalian Cell Cult
Effect of in ovo Feeding of Graded Levels of L-glutamine on Blood Biochemistry, Colour and Texture of Selected Muscles,
Elucidating uptake and metabolic fate of dipeptides in CHO cell cultures using 13C labeling experiments and kinetic mode
DL-methionyl-DL-methionine as an efficient methionine source for promoting zootechnical performance and methionine-relat
Multi-Omics Reveals Impact of Hypoxia on Lactate Metabolic Switch and Monoclonal Antibody Production in CHO Fed-Batch Cu
Enhancing recombinant antibody yield in Chinese hamster ovary cells.
Novel Kv7.1 missense mutation Lys422Glu leads to the development of LQT syndrome
Dietary ribose supplementation improves flesh quality through purine metabolism in gibel carp (Carassius auratus gibelio
Effect of organic selenium dietary supplementation on quality and fertility of cryopreserved chicken sperm.
Sulforaphane attenuates HFD-induced enteritis in yellow river carp by restoring immune homeostasis, repairing intestinal
S-Sulfocysteine - Investigation of cellular uptake in CHO cells.
Effects of dietary serine addition to a high plant protein diet on growth performance, body composition, hepatosomatic h
Optimization of amino acid composition in CHO cell perfusion medium using definitive screening design and 1H NMR-based c
Multivariate data analysis of growth medium trends affecting antibody glycosylation
Too Much of a Good Thing: Rethinking Feed Formulation and Feeding Practices for Zinc in Swine Diets to Achieve One Healt
Perfusion culture of Chinese Hamster Ovary cells for bioprocessing applications.
Therapeutic modulation of Alzheimer’s disease with biological (HUCBS) and pharmacological (LISPRO) approaches
Evaluation of Cellular Mechanisms Involved in Recombinant Antibody Expression in Transiently Transfected Chinese Hamster
Effect of dietary supplementation or cessation of magnesium-based alkalizers on milk fat output in dairy cows under milk
Monitoring Intracellular Metabolite Dynamics in Saccharomyces cerevisiae during Industrially Relevant Famine Stimuli
Impact of dietary Lactobacillus supplementation on intramuscular fat deposition and meat quality of Sunit sheep.
Supplementation with Major Royal-Jelly Proteins Increases Lifespan, Feeding, and Fecundity in Drosophila.
Thrombomodulin is essential for recombinant Fc-fusion protein production in Chinese hamster ovary cells via multiple sig
NAD+ supplementation improves mAb productivity in CHO cells via a glucose metabolic shift
A Systematic Approach to Time-series Metabolite Profiling and RNA-seq Analysis of Chinese Hamster Ovary Cell Culture
High-Throughput Platform Development for Chinese Hamster Ovary (CHO) Cell Culture Performance Enhancement Using Small Mo
Parallelized microscale fed-batch cultivation in online-monitored microtiter plates: implications of media composition a
Development and application of quantitative liquid chromatography – mass spectrometry techniques to facilitate enhanced
Evaluation of dietary arginine supplementation to increase placental nutrient transporters in aged mares
13 C Flux Analysis Reveals that Rebalancing Medium Amino Acid Composition can Reduce Ammonia Production while Preserving
Feeding strategy impacts heterologous protein production in Yarrowia lipolytica fed-batch cultures-Insight into the role
Impact of iron raw materials and their impurities on CHO metabolism and recombinant protein product quality
Branched-Chain Amino Acids Target miR-203a/fosb Axis to Promote Skeletal Muscle Growth in Common Carp (Cyprinus carpio)
Transcriptomic Analysis of Pichia pastoris (Komagataella phaffii) GS115 During Heterologous Protein Production Using a H
First record of geophagy in Jungle Babbler (Turdoides striata) prior to egg-laying: an instinct for calcium supplement.
Elevated endoplasmic reticulum pH is associated with high growth and bisAb aggregation in CHO cells.
High cell density transient transfection of CHO cells for TGF‐β1 expression
Impact of cell culture media additives on IgG glycosylation produced in Chinese hamster ovary cells
Deciphering the determinants of recombinant protein expression across the human secretome.
Compartmentalized Proteomic Profiling Outlines the Crucial Role of the Classical Secretory Pathway during Recombinant Pr
Evaluation of artificial signal peptides for secretion of two lysosomal enzymes in CHO cells
Effects of hydrogen peroxide and l-tryptophan on antioxidative potential, apoptosis, and mammalian target of rapamycin s
Serum-Free Medium for Recombinant Protein Expression in Chinese Hamster Ovary Cells.
Effect of cell culture medium additives on color and acidic charge variants of a monoclonal antibody.
A metabolic network-based approach for developing feeding strategies for CHO cells to increase monoclonal antibody produ
Restoring In Vivo-Like Membrane Lipidomics Promotes Exosome Trophic Behavior from Human Placental Mesenchymal Stromal/St
Optimization of a mAb production process with regard to robustness and product quality using quality by design principle
Principles and approach to developing mammalian cell culture media for high cell density perfusion process leveraging es
A natural bioactive feed additive alters expression of genes involved in inflammation in whole blood of healthy Angus he
Data-driven modeling of the degradation of recombinant proteins in Chinese hamster ovary cells
Mitochondrial Hyperfusion Via Metabolic Sensing of Regulatory Amino Acids
Expression of Human Erythropoietin Containing 2 Additional N-Link in CHO-K1 Cells under Different Culture Conditions
Characterization of the Ubiquitin-Modified Proteome of Recombinant Chinese Hamster Ovary Cells in Response to Endoplasmi
67 Effect of Different Dietary Protein Sources on Skeletal Muscle Growth Characteristics and Satellite Cell Mitotic Acti
Effects of Dietary Glycine Supplementation on Growth Performance, Immunological, and Erythrocyte Antioxidant Parameters
Establishment and optimization of a high-throughput mimic perfusion model in ambr® 15.
Amino Acid Transport Associated to Cluster of Differentiation 98 Heavy Chain (CD98hc) Is at the Cross-road of Oxidative
Inferring secretory and metabolic pathway activity from omic data with secCellFie.
Nutrient Optimization Reduces Phosphorylation and Hydroxylation Level on an Fc-Fusion Protein in a CHO Fed-Batch Process
The contributions of individual galactosyltransferases to protein specific N-glycan processing in Chinese Hamster Ovary
Whole‐cell <i>Escherichia coli</i> lactate biosensor for monitoring mammalian cell cultures during biopharmaceutical pro
S-adenosylmethionine and methylthioadenosine boost cellular productivities of antibody forming Chinese hamster ovary cel
Transcriptome Analysis Suggests Dietary Tributyrin Enhances Feeding Intensity via Modulating Steroid Biosynthesis in Man
Preventing pyruvate kinase muscle expression in Chinese hamster ovary cells curbs lactogenic behavior by altering glycol
Deciphering Metabolic Pathways in High-Seeding-Density Fed-Batch Processes for Monoclonal Antibody Production: A Computa
Explainable AI for CHO cell culture media optimization and prediction of critical quality attribute.
Impacts of feeding milk replacer supplemented with increasing concentrations of choline on feed intake, growth, and scou
Towards Autonomous Process Control—Digital Twin for CHO Cell-Based Antibody Manufacturing Using a Dynamic Metabolic Mode
Controlling the time evolution of mAb N-linked glycosylation, Part I: Microbioreactor experiments.
Fecal Microbiota and Performance of Dairy Cattle from a West Mexican Family Dairy Farm Supplemented with a Fiber-Degradi
In silico model-based characterization of metabolic response to harsh sparging stress in fed-batch CHO cell cultures.
Bioprocess development of antibody-drug conjugate production for cancer treatment
Rapid development of clone‐specific, high‐performing perfusion media from established feed supplements
Metabolic engineering of CHO cells towards cysteine prototrophy and systems analysis of the ensuing phenotype.
Production and Purification of Antibodies in Chinese Hamster Ovary Cells.
Tuning monoclonal antibody galactosylation using Raman spectroscopy-controlled lactic acid feeding.
Effects and mechanisms of animal-free hydrolysates on recombination protein yields in CHO cells.
Self-control design reveals varied lactation and metabolic responses to rumen-protected methionine in dairy cows
Antioxidant effect of thiazolidine molecules in cell culture media improves stability and performance.
Supplementation of Methionine Dipeptide Enhances the Milking Performance of Lactating Dairy Cows
The Various Roles of Fatty Acids
Toward Machine Learning-Guided CHO Bioprocess and Media Optimization for Improved Titer and Glycosylation.
Optimization of Culture Conditions to Improve Follicle-Stimulating Hormone Production by CHO-DG44 Cells in Serum-Free Me
Affecting HEK293 Cell Growth and Production Performance by Modifying the Expression of Specific Genes.
Mechanistic insights into sodium citrate-induced metabolic rewiring for enhanced S-adenosylmethionine synthesis via tran
Increased recombinant AAV production by HEK293 cells using small molecule chemical additives
Influence of dietary resveratrol supplementation on integrity and colloidal characteristics of Myofibrillar proteins in
Effect of food supplementation on in vitro embryo production and growth performance in prepubertal Nelore heifers.
Safety and efficacy of l‐arginine produced by fermentation using Corynebacterium glutamicum KCCM 10741P for all animal s
Overexpression of the regulatory subunit of glutamate-cysteine ligase enhances monoclonal antibody production in CHO cel
Screening Strategies for High-Yield Chinese Hamster Ovary Cell Clones
Recombinase-Mediated Cassette Exchange-Based CRISPR Activation Screening Identifies Hyperosmotic Stress-Resistant Genes
Transcriptome Adaptation of the Ovine Mammary Gland to Dietary Supplementation of Extruded Linseed.
Comprehensive manipulation of glycosylation profiles across development scales.
Integrated Serum Metabolome and Gut Microbiome to Decipher Chicken Amino Acid Improvements Induced by Medium-Chain Monog
Semi-continuous scale-down models for clone and operating parameter screening in perfusion bioreactors.
Soft-sensors application for automated feeding control in high-throughput mammalian cell cultures.
Transferability of miRNA-technology to bioprocessing: Influence of cultivation mode and media.
Recent advances in fed-batch microscale bioreactor design.
Heterotrophically Ultrahigh-Cell-Density Cultivation of a High Protein-Yielding Unicellular Alga Chlorella With a Novel
Evaluation of feed strategy for high quality biosimilar IgG production in CHO cell fed-batch process
Impact of S-sulfocysteine on fragments and trisulfide bond linkages in monoclonal antibodies.
Citrulline production and protein homeostasis.
Dietary stevioside supplementation increases feed intake by altering the hypothalamic transcriptome profile and gut micr
Impact of maternal antioxidant supplementation on ovarian development in prepuberal Iberian pig offspring.
An unconventional uptake rate objective function approach enhances applicability of genome-scale models for mammalian ce
Systems biology and metabolic modeling for cultivated meat: A promising approach for cell culture media optimization and
Addressing amino acid-derived inhibitory metabolites and enhancing CHO cell culture performance through DOE-guided media
CHO stable pool fed-batch process development of SARS-CoV-2 spike protein production: Impact of aeration conditions and
Capillary and microchip electrophoresis method development for amino acid monitoring during biopharmaceutical cultivatio
Adaptation process of engineered cell line FCHO/IL-24 stably secreted rhIL-24 in serum-free suspension culture.
A multimodal digital microfluidic testing platform for antibody-producing cell lines.
Assessment of fed-batch cultivation strategies for an inducible CHO cell line.
Seryl-tRNA synthetase-mediated essential amino acids regulate β-casein synthesis via cell proliferation and mammalian ta
Genome-Scale Modeling of CHO Cells Unravel the Critical Role of Asparagine in Cell Culture Feed Media.
Effects of Organic Selenium Supplementation on Growth, Accumulation, Haematology and Histopathology of Juvenile Barramun
Integrated Transcriptomic Analyses of Liver and Mammary Gland Tissues Reveals the Regulatory Mechanism Underlying Dairy
A novel method based on nonparametric regression with a Gaussian kernel algorithm identifies the critical components in
Enhanced production of recombinant proteins by a small molecule protein synthesis enhancer in combination with an antiox
Effects of monensin feeding on performance, nutrient utilisation and enteric methane production in growing buffalo heife
Updated transient gene expression protocol and the development of a small-scale transient gene expression protocol -eval
Metabolic analysis of the asparagine and glutamine dynamics in an industrial Chinese hamster ovary fed‐batch process
Metabolic status, reproductive, and productive performances of transition dairy cows as affected by dietary rumen-protec
Poria cocos Polysaccharide Delays Aging by Enhancing the Antioxidant Ability and Suppressing the Expression of the Branc
Principles and approach to developing mammalian cell culture media for high cell density perfusion process leveraging es
Differential expression of microRNAs in recombinant Chinese hamster ovary cells treated with sodium butyrate using digit
Quantifying the impact of cell culture media on CHO cell growth and protein production.
Effects of fat supplementation on plasma glucose, insulin and fatty acid analysis in ponies maintained on a forage-based
Different feeding strategies can affect growth performance and rumen functions in Gangba sheep as revealed by integrated
Glycosylation Flux Analysis of Immunoglobulin G in Chinese Hamster Ovary Perfusion Cell Culture
Effects of Ala-Gln feeding strategies on growth, metabolism, and crowding stress resistance of juvenile Cyprinus carpio
Metabolomic characterization of monoclonal antibody-producing Chinese hamster lung (CHL)-YN cells in glucose-controlled
Effects of Supplementation of Branched-Chain Amino Acids to Reduced-Protein Diet on Skeletal Muscle Protein Synthesis an
Strategies to improve CHO cell culture performance: Targeted deletion of amino acid catabolism and apoptosis genes paire
From Cell Clones to Recombinant Protein Product Heterogeneity in Chinese Hamster Ovary Cell Systems.
Mechanisms driving the lactate switch in Chinese hamster ovary cells
Serum-Free and Protein-Free Media for the Cultivation of Recombinant Chinese Hamster Ovary (CHO) Cell Lines.
Optimized quantification of fatty acids in complex media using advanced analytical techniques.
Two industrial media reveal a mitochondrial disfunction in CHO cell cultures co-fed with glucose and lactic acid.
Epigenetic regulation of gene expression in Chinese Hamster Ovary cells in response to the changing environment of a bat
Preventing pyruvate kinase muscle expression in Chinese hamster ovary cells curbs lactogenic behavior by altering glycol
Using Metabolomics to Identify Cell Line-Independent Indicators of Growth Inhibition for Chinese Hamster Ovary Cell-base
Engineer Medium and Feed for Modulating N-Glycosylation of Recombinant Protein Production in CHO Cell Culture.
Fine-Tuning of Postprandial Responses via Feeding Frequency and Leucine Supplementation Affects Dietary Performance in T
The use of 'Omics technology to rationally improve industrial mammalian cell line performance.
High cysteine concentrations in cell culture media lead to oxidative stress and reduced bioprocess performance of recomb
High Nutritional Conditions Influence Feeding Plasticity in Pristionchus pacificus and Render Worms Non-Predatory.
Mineral nutrition and bone health in salmonids
Evaluation of the Role of Soybean Lecithin, Egg Yolk Lecithin, and Krill Oil in Promoting Ovarian Development in the Fem
Genome-scale functional genomics screening highlights genes impacting protein fucosylation in Chinese hamster ovary cell
Arginine Relieves the Inflammatory Response and Enhances the Casein Expression in Bovine Mammary Epithelial Cells Induce
Effects of selenium supplementation on chemical composition and aromatic profiles of cow milk and its derived cheese.
Increased recombinant adeno‐associated virus production by HEK293 cells using small molecule chemical additives
Effects of Dietary Supplementation of Coenzyme Q10 on Growth Performance, Biochemical and Physiological Attributes of Ra
Real‐time amino acid and glucose monitoring system for the automatic control of nutrient feeding in CHO cell culture usi
Digital Twins and Their Role in Model-Assisted Design of Experiments.
Chemical inhibitors of hexokinase‐2 enzyme reduce lactate accumulation, alter glycosylation processing, and produce alte
Arginine Supply Impacts the Expression of Candidate microRNA Controlling Milk Casein Yield in Bovine Mammary Tissue
FACTORS AFFECTING CHINESE HAMSTER OVARY CELL PROLIFERATION AND VIABILITY
Crosstalk Between Protein Restriction and Fasting and Its Impacts on Growth, Digestive Enzymes, Immunity, Antioxidant Ac
Folate deficiency and over-supplementation causes impaired folate metabolism: Regulation and adaptation mechanisms in Ca
Choline Supplementation Normalizes Fetal Adiposity and Reduces Lipogenic Gene Expression in a Mouse Model of Maternal Ob
Hybrid modeling for in silico optimization of a dynamic perfusion cell culture process.
Protective role of l‐threonine against cadmium toxicity in Saccharomyces cerevisiae
A theoretical estimate for nucleotide sugar demand towards Chinese Hamster Ovary cellular glycosylation.
Decoding Complexity in Metabolic Networks using Integrated Mechanistic and Machine Learning Approaches
Raman‐based dynamic feeding strategies using real‐time glucose concentration monitoring system during adalimumab produci
Improved Performance in Mammalian Cell Perfusion Cultures by Growth Inhibition.
Carnitine in Human Muscle Bioenergetics: Can Carnitine Supplementation Improve Physical Exercise?
Effects of vitamin A supplementation on ovarian development of Astyanax lacustris (Teleostei: Characidae) during the non
Effects of dietary N-carbamylglutamate supplementation on milk production performance, nutrient digestibility and blood
Expression in CHO cells of a bacterial biosynthetic pathway producing a small non-ribosomal peptide aldehyde prevents pr
Differential effects of bioreactor process variables and purification on the human recombinant lysosomal enzyme β-glucur
Modeling the Effect of Amino Acids and Copper on Monoclonal Antibody Productivity and Glycosylation: A Modular Approach.
Optimization of parameters affecting on CHO cell culture producing recombinant erythropoietin.
Combination of dextran sulfate and recombinant trypsin on aggregation of Chinese hamster ovary cells.
Dietary Sodium Butyrate Supplementation Enhances Silkworm Silk Yield by Simultaneously Promoting Larval Growth and Silk
Effect of cell culture medium additives on color and acidic charge variants of a monoclonal antibody.
Real‐time quantification and supplementation of bioreactor amino acids to prolong culture time and maintain antibody pro
Composition and colour indices of sheep’s bulk-tank milk are influenced by production practices
Attenuating apoptosis in Chinese hamster ovary cells for improved biopharmaceutical production
Proteomics Profiling of Chimeric-Truncated Tissue Plasminogen activator Producing- Chinese Hamster Ovary Cells Cultivate
Enzyme capacity-based genome scale modelling of CHO cells.
Dietary Chromium Picolinate Supplementation Affects Growth, Whole-Body Composition, and Gene Expression Related to Gluco
Effects of dietary supplementation of Bacillus subtilis DSM 32315 on growth, immune response and acute ammonia stress to
Transcriptome Analysis of CHO Cell Size Increase During a Fed-Batch Process
Positive effects of dietary supplementation of three probiotics on milk yield, milk composition and intestinal flora in
Pre-stage perfusion and ultra-high seeding cell density in CHO fed-batch culture: a case study for process intensificati
Unraveling the metabolic and machinery constraints on protein secretion through a novel systems biology framework
Profiling the dynamic changes in the phosphoproteome of Chinese hamster ovary cells
A statistical approach to improve compound screening in cell culture media
Dietary zinc source impacts intestinal morphology and oxidative stress in young broilers
Boosting Productivity for Advanced Biomanufacturing by Re-Using Viable Cells.
Dietary supplementation with curcumin nanomicelles, curcumin, and turmeric affects growth performance and silver nanopar
Optimization of Key Factors in Serum Free Medium for Production of Human Recombinant GM-CSF Using Response Surface Metho
Low-cost food-grade alternatives for serum albumins in FBS-free cell culture media.
Quantitative Proteomics Revealed the Molecular Regulatory Network of Lysine and the Effects of Lysine Supplementation on
Use of High-Throughput Automated Microbioreactor System for Production of Model IgG1 in CHO Cells.
Parallel experimental design and multivariate analysis provides efficient screening of cell culture media supplements to
Interaction of supplementary L-carnitine and dietary energy levels on feed utilization and blood constituents in New Zea
Therapeutic glycoprotein production in mammalian cells
Identification of octopus peptide and its promotion of β-casein synthesis in a mouse mammary epithelial cell line.
Cysteine in cell culture media induces acidic IgG1 species by disrupting the disulfide bond network.
Use of single analytic tool to quantify both absolute N‐glycosylation and glycan distribution in monoclonal antibodies
Monitoring utilizations of amino acids and vitamins in culture media and Chinese hamster ovary cells by liquid chromatog
A Metabolomics Approach to Increasing Chinese Hamster Ovary (CHO) Cell Productivity
Leucine can modulate the expression of proteins related to protein degradation signalling under mTOR inhibition in C2C12
A nutrition algorithm to optimize feed and medium composition using genome-scale metabolic models.
Tracking dipeptides at work-uptake and intracellular fate in CHO culture.
Cell-culture process optimization via model-based predictions of metabolism and protein glycosylation.
An automated high inoculation density fed‐batch bioreactor, enabled through N‐1 perfusion, accommodates clonal diversity
Metabolic responses and pathway changes of mammalian cells under different culture conditions with media supplementation
Successful Inclusion of High Vegetable Protein Sources in Feed for Rainbow Trout without Decrement in Intestinal Health
Culture media optimization for Chinese hamster ovary cell growth and expression of recombinant varicella-zoster virus gl
Characterisation of the Scs system that confers copper tolerance in Salmonella enterica serovar Typhimurium
Effects of Dietary Inosine 5'-Monophosphate Supplementation on the Growth Performance and Salinity and Oxidative St
Animal‐cell culture media: History, characteristics, and current issues
Leucine and Mammalian Target of Rapamycin-Dependent Activation of Muscle Protein Synthesis in Aging.
Enhancement of anti-TNFα monoclonal antibody production in CHO cells through the use of UCOE and DHFR elements in vector
The biological role of chromium is the rationale, experience and prospects of its application to cattle
Methionine Metabolism Alters Oxidative Stress Resistance via the Pentose Phosphate Pathway
Computer-Aided Strategies for Determining the Amino Acid Composition of Medium for Chinese Hamster Ovary Cell-Based Biom
Systematic development of temperature shift strategies for Chinese hamster ovary cells based on short duration cultures
Overexpression of G6PDH does not affect the behavior of HEK-293 clones stably expressing interferon-α2b
Effects of an herbal adaptogen feed-additive on feeding-related hypothalamic neuropeptides in chronic cyclic heat-stress
Improvement of growth rates through nucleoside media supplementation of CHO clones.
Continuous optical in‐line glucose monitoring and control in CHO cultures contributes to enhanced metabolic efficiency w
Integrating real-time OUR monitoring with adaptive feeding for enhanced antibody production.
Immune response, productivity and quality of milk from grazing goats as affected by dietary polyunsaturated fatty acid s
Restricted feeding regimens improve white striping associated muscular defects in broiler chickens.
Differential gene expression of a feed-spiked super-producing CHO cell line.
Long-Term Feeding with Curcumin Affects the Growth, Antioxidant Capacity, Immune Status, Tissue Histoarchitecture, Immun
Exploring the capabilities of fluorometric online monitoring on chinese hamster ovary cell cultivations producing a mono
Repeated fed-batch strategy and metabolomic analysis to achieve high docosahexaenoic acid productivity in Crypthecodiniu
Valeric acid induces cell cycle arrest at G1 phase in CHO cell cultures and improves recombinant antibody productivity.
Multivariate data analysis of process parameters affecting the growth and productivity of stable Chinese hamster ovary c
Relation between feeding behaviour and energy metabolism in pigs fed diets enriched in dietary fibre and wheat aleurone.
Process intensification to produce a difficult-to-express therapeutic enzyme by high cell density perfusion or enhanced
Enzyme-treated soy protein supplementation in low protein diet enhanced immune function of immune organs in on-growing g
Improved recombinant protein production by regulation of transcription and protein transport in Chinese hamster ovary ce
Development of Saccharomyces cerevisiae as a recombinant antibody factory
Accelerating Biologics Manufacturing by Upstream Process Modelling
Effects of Feeding Coenzyme Q10-Ubiquinol on Plasma Coenzyme Q10 Concentrations and Semen Quality in Stallions.
In-silico media optimization for continuous cultures using genome scale metabolic networks: The case of CHO-K1.
Physiological Functions of Threonine in Animals: Beyond Nutrition Metabolism
199 Supplemental arginine affects intestinal gene expression and serum concentration of amino acids of heat stress pigs
Impact of probiotic Bacillus sp. dietary supplementation on pancreatic and intestinal activities in seabream Sparus aura
Chlorella vulgaris Extract as a Serum Replacement That Enhances Mammalian Cell Growth and Protein Expression.
Compartment-specific metabolome labeling enables the identification of subcellular fluxes that may serve as promising me
Optimization of a transient antibody expression platform towards high titer and efficiency.
High-Throughput Screening Identifies Two Novel Small Molecule Enhancers of Recombinant Protein Expression
ManNAc attenuates Man5 glycoform abundance through GNE-mediated metabolic channeling of UDP-GlcNAc to N-glycosylation mo
Characterization of Monoclonal Antibody Glycan Heterogeneity Using Hydrophilic Interaction Liquid Chromatography-Mass Sp
Progress in fed-batch culture for recombinant protein production in CHO cells
Genetic mechanisms underlying feed utilization and implementation of genomic selection for improved feed efficiency in d
Effects of branched-chain amino acids on glucose uptake and lactose synthesis rates in bovine mammary epithelial cells a
Effects of peptone on hybridoma growth and monoclona ! antibody formation
Amino Acid Metabolomic Profiles in Bovine Mammary Epithelial Cells under Essential Amino Acid Restriction
CHOmpact: A reduced metabolic model of Chinese hamster ovary cells with enhanced interpretability.
Ala-Cys-Cys-Ala dipeptide dimer alleviates problematic cysteine and cystine levels in media formulations and enhances CH
Influence of Amino Acid Feeding on Production of Calcimycin and Analogs in Streptomyces chartreusis.
Bip inducer X: an ER stress inhibitor for enhancing recombinant antibody production in CHO cell culture.
CHO stable pool fed-batch process development of SARS-CoV-2 spike protein production: Impact of aeration conditions and
Effects of feeding difructose anhydride on the mineral status and milking performance of transition cows.
Raman-based dynamic feeding strategies using real-time glucose concentration monitoring system during adalimumab produci
Flux Sampling Suggests Metabolic Signatures of High Antibody-Producing CHO Cells.
Valine increases milk fat synthesis in mammary gland of gilts through stimulating AKT/MTOR/SREBP1 pathway†
Dietary Sodium Butyrate Supplementation Promotes Oxidative Fiber Formation in Mice.
Dietary Methionine Supplementation Improves Rainbow Trout (Oncorhynchus mykiss) Immune Responses Against Viral Haemorrha
Addressing amino acid‐derived inhibitory metabolites and enhancing CHO cell culture performance through DOE‐guided media
Evaluating dynamic effects of dietary glycerol monolaurate on the productive performance and flesh quality of large yell
Bioprocessing of Recombinant CHO-K1, CHO-DG44, and CHO-S: CHO Expression Hosts Favor Either mAb Production or Biomass Sy
Diets derived from maize monoculture cause maternal infanticides in the endangered European hamster due to a vitamin B3
45 Opportunity with functional role of supplemental amino acids
Multi-Omics Reveals Impact of Cysteine Feed Concentration and Resulting Redox Imbalance on Cellular Energy Metabolism an
Intracellular CHO cell metabolite profiling and in vivo monitoring of redox state unravel the effect of temperature down
Identification and control of novel growth inhibitors in fed-batch cultures of Chinese hamster ovary cells.
LC-HRMS-based targeted metabolomics for high-throughput and quantitative analysis of 21 growth inhibition-related metabo
Affecting HEK293 Cell Growth and Production Performance by Modifying the Expression of Specific Genes
Controlling the Glycosylation Profile in mAbs Using Time-Dependent Media Supplementation.
Utilizing Cole-Cole parameters for in-line feedback: Cell culture process adjustments based on cell health.
High Cell Density Perfusion Culture has a Maintained Exoproteome and Metabolome
Diffusion and Inhibition Processes in a Hollow-fiber Membrane Bioreactor for Hybridoma Culture. Development of a Mathema
Supplementation of sulfur and folic acid improves performance of broiler chicken fed suboptimal concentrations of dietar
Single-Use Printed Biosensor for L-Lactate and Its Application in Bioprocess Monitoring
Harnessing metabolic plasticity in CHO cells for enhanced perfusion cultivation
Combined gene and environmental engineering offers a synergetic strategy to enhance r-protein production in Chinese hams
Epigallocatechin-3-gallate supplementation regulates glucose redistribution through its potential endogenous receptor in
A dynamic model linking cell growth to intracellular metabolism and extracellular by‐product accumulation
Amélioration de la production et de la qualité des protéines thérapeutiques recombinantes produites en culture en mode c
Effects of bioprocessed soybean meal and nucleotide supplementation on growth, physiology and histomorphology in largemo
Effects of cottonseed meal bioactive peptides on growth performance, ileal digestibility, serum amino acid and immune re
Reduction of charge variants by CHO cell culture process optimization.
Effects of intravenous arginine infusion on inflammation and metabolic indices of dairy cows in early lactation.
Large-scale cultivation of Caenorhabditis elegans in a bioreactor using a labor-friendly fed-batch approach.
Flux Sampling Suggests Metabolic Signatures of High Antibody-Producing CHO Cells.
Metabolic Control in Mammalian Fed-Batch Cell Cultures for Reduced Lactic Acid Accumulation and Improved Process Robustn
Controlling the time evolution of mAb N-linked glycosylation, Part I: Microbioreactor experiments.
Methods for Using Small Non-Coding RNAs to Improve Recombinant Protein Expression in Mammalian Cells
Effects of Protein Supplementation Strategy and Genotype on Milk Production and Nitrogen Utilisation Efficiency in Late-
Bioprocess biomarker identification and diagnosis for industrial mAb production based on metabolic profiling and multiva
A genome-scale metabolic network model and machine learning predict amino acid concentrations in Chinese Hamster Ovary c
miRNA profiling of high, low and non-producing CHO cells during biphasic fed-batch cultivation reveals process relevant
Optimization of recombinant antibody production based on the vector design and the level of metabolites for generation o
Nutrient supplementation strategy improves cell concentration and longevity, monoclonal antibody production and lactate
<i>Pichia pastoris</i>: A highly successful expression system for optimal synthesis of heterologous proteins
Integration of Bayesian optimization and solution thermodynamics to optimize media design for mammalian biomanufacturing
Media on‐demand: Continuous reconstitution of a chemically defined media directly from solids
Acidic Derivatization of Thiols Using Diethyl 2-Methylenemalonate: Thiol-Michael Addition Click Reaction for Simultaneou
Lactate Control Enhances Growth Advantage in Fed-batch Cultures of Metabolically Engineered CHO Cells with Reduced Novel
Development of an Animal-Derived Component-Free Medium for Spodoptera frugiperda (Sf9) Cells Using Response Surface Meth
Identification of milk-related genes and regulatory networks in Bactrian camel either supplemented or under grazing.
All-trans retinoic acid in combination with sodium butyrate enhances specific monoclonal antibody productivity in recomb
A Markov model of glycosylation elucidates isozyme specificity and glycosyltransferase interactions for glycoengineering
Optimization of parameters affecting on CHO cell culture producing recombinant erythropoietin.
The effect of amino acid supplementation in an industrial Chinese Hamster Ovary process.
Genome‐scale metabolic models applied for human health and biopharmaceutical engineering
Characterization of glutathione proteome in CHO cells and its relationship with productivity and cholesterol synthesis
Improvement strategies for transient gene expression in mammalian cells.
Optimization of a high-cell-density polyethylenimine transfection method for rapid protein production in CHO-EBNA1 cells
Dietary cobalt supplementation improves growth and body composition and induces the expression of growth and stress resp
EPA and DHA promote cell proliferation and enhance activity of the Akt-TOR-S6K anabolic signaling pathway in primary mus
Effects of Dietary Supplementation of Lauric Acid on Lactation Function, Mammary Gland Development, and Serum Lipid Meta
Reconstruction of reverse transsulfuration pathway enables cysteine biosynthesis and enhances resilience to oxidative st
The effect of amino acid supplementation in an industrial Chinese Hamster Ovary process.
Predictive macroscopic modeling of cell growth, metabolism and monoclonal antibody production: Case study of a CHO fed-b
Increasing the availability of threonine, isoleucine, valine, and leucine relative to lysine while maintaining an ideal
Effects of Ala-Gln feeding strategies on growth, metabolism, and crowding stress resistance of juvenile Cyprinus carpio
Towards the development of automated fed-batch cell culture processes at microscale.
Identification and control of novel growth inhibitors in fed-batch cultures of Chinese hamster ovary cells.
Improving the secretory capacity of Chinese hamster ovary cells by ectopic expression of effector genes: Lessons learned
Biology-aware machine learning for culture medium optimization.
Methylcellulose has synergistic growth benefits with poloxamer in suspension CHO culture.
Application of metabolic modeling for targeted optimization of high seeding density processes
Possible fetal bovine serum-reduced boost cultivation of DF-1 by supplementation with plant peptones and yeast extracts
Effect of Supplementation of Various Sources of Methionine on Nutrient Digestibility and Intestinal Morphometry in Broil
High glucose enhances cAMP level and extracellular signal-regulated kinase phosphorylation in Chinese hamster ovary cell
Advances in Escherichia coli-Based Therapeutic Protein Expression: Mammalian Conversion, Continuous Manufacturing, and C
Influence of ammonia and lysine supplementation on yeast growth and fermentation with respect to gluten‐free type brewin
Screening and selection strategy for the establishment of biosimilar to trastuzumab-expressing CHO-K1 cell lines.
Effect of N-acetyl cysteine and glycine supplementation on growth performance, glutathione synthesis, and antioxidative
“Organized stress” for robust scale‐up of intensified production process with fed‐batch seed bioreactor
Differential polyamine metabolism in CHO cell lines: Insights into cell growth and antibody quality.
Stress‐induced increase of monoclonal antibody production in CHO cells
Improving titer while maintaining quality of final formulated drug substance via optimization of CHO cell culture condit
Impact of Nitrogen Addition on Wine Fermentation by S. cerevisiae Strains with Different Nitrogen Requirements.
Are the Main Methionine Sources Equivalent? A Focus on DL-Methionine and DL-Methionine Hydroxy Analog Reveals Difference
Dietary Tryptophan Plays a Role as an Anti-Inflammatory Agent in European Seabass (Dicentrarchus labrax) Juveniles durin
Redefining media blending mathematically: a systematic approach for screening of medium components.
Improvement of growth rates through nucleoside media supplementation of CHO clones
Dietary guanidinoacetic acid supplementation improves water holding capacity and lowers free amino acid concentration of
Characterization of Chinese Hamster Ovary Cell Performance with Pentanoic Acid and N-Acetyl Cysteine Treatment
Supplementation of Foals with a Saccharomyces cerevisiae Fermentation Product Alters the Early Response to Vaccination.
Transfection of miR-31* boosts oxidative phosphorylation metabolism in the mitochondria and enhances recombinant protein
Mouse WIF1 Is Only Modified with O-Fucose in Its EGF-like Domain III Despite Two Evolutionarily Conserved Consensus Site
Rich production media as a platform for CHO cell line development.
Dietary creatine and guanidinoacetic acid supplementation have limited effects on hybrid striped bass.
Dietary indispensable amino acids profile affects protein utilization and growth of Senegalese sole larvae.
Evaluation of NAD+ precursors for improved metabolism and productivity of antibody-producing CHO cell.
Model‐based investigation of intracellular processes determining antibody Fc‐glycosylation under mild hypothermia
Effect of amino acid supplementation on titer and glycosylation distribution in hybridoma cell cultures—Systems biology‐
Leveraging machine learning to dissect role of combinations of amino acids in modulating the effect of zinc on mammalian
Glutamine Metabolism Is Essential for Stemness of Bone Marrow Mesenchymal Stem Cells and Bone Homeostasis
A Chronic Fetal Leucine Infusion Potentiates Fetal Insulin Secretion and Increases Pancreatic Islet Size, Vascularity, a
Effect of co-overexpression of the cargo receptor ERGIC-53/MCFD2 on antibody production and intracellular IgG secretion
Comparative effect of methionine and cysteine supplementation on growth performance and blood profile of Desi chicks
Investigation into the impact of tyrosine on the product formation and quality attributes of mAbs in rCHO cell cultures.
Effects of dietary hydrolysate supplementation on growth, body composition, hematological responses, and liver histology
Effects of different durations of fasting/re-feeding bouts on growth, biochemical and histological changes in the digest
Transcriptomic changes in CHO cells after adaptation to suspension growth in protein-free medium analysed by a species-s
Raman-controlled pyruvate feeding to control metabolic activity and product quality in continuous biomanufacturing.
Methylthioadenosine (MTA) boosts cell‐specific productivities of Chinese hamster ovary cultures: dosage effects on proli
Enhancing Human Glycoprotein Hormones Production in CHO Cells Using Heterologous Beta-Chain Signal Peptides.
Combination of temperature shift and hydrolysate addition regulates anti-IgE monoclonal antibody charge heterogeneity in
Real-time amino acid and glucose monitoring system for the automatic control of nutrient feeding in CHO cell culture usi
TRIENNIAL REPRODUCTION SYMPOSIUM: Beef heifer development and lifetime productivity in rangeland-based production system
Using MVDA with stoichiometric balances to optimize amino acid concentrations in chemically defined CHO cell culture med
Cell Engineering for Increasing Production of Recombinant Proteins in Mammalian Cells.
Bridging Offline Functional Model Carrying Aging-Specific Growth Rate Information and Recombinant Protein Expression: En
Enhancing Metabolism and Milk Production Performance in Periparturient Dairy Cattle through Rumen-Protected Methionine a
Process development for the continuous production of heterologous proteins by the industrial yeast, Komagataella phaffii
Production of a Dulaglutide Analogue by Apoptosis-Resistant Chinese Hamster Ovary Cells in a 3-Week Fed-Batch Process.
Whole-genome DNA methylation analysis of Chinese hamster ovary cells undergoing media adaptation.
Enhancement of adalimumab expression in CHO cells by antioxidant small molecule additives and the underlying mechanism
CHOmpact: A reduced metabolic model of Chinese hamster ovary cells with enhanced interpretability
Strategy for Developing a Stable CHO Cell Line that Produces Large Titers of Trastuzumab Antibody.
Butyrated ManNAc analog improves protein expression in Chinese hamster ovary cells.
Chemically defined media modifications to lower tryptophan oxidation of biopharmaceuticals.
Autophagy-inducing Peptide Increases CHO Cell Monoclonal Antibody Production in Batch and Fed-batch Cultures
Real‐time monitoring of specific oxygen uptake rates of embryonic stem cells in a microfluidic cell culture device
Purification and Analytics of a Monoclonal Antibody from Chinese Hamster Ovary Cells Using an Automated Microbioreactor
Dietary Whey Protein Supplementation Increases Immunoglobulin G Production by Affecting Helper T Cell Populations after
Characterization of mammalian cell culture raw materials by combining spectroscopy and chemometrics
Impact of cell culture media additives on IgG glycosylation produced in Chinese hamster ovary cells
Intensified Influenza Virus Production in Suspension HEK293SF Cell Cultures Operated in Fed-Batch or Perfusion with Cont
Transcriptomic signature of high dietary organic selenium supplementation in sheep: A nutrigenomic insight using a custo
Rapid metabolic regulation of a novel arginine methylation of KCa3.1 attenuates 1 T cell exhaustion 2257
Growth Performance and Microbial Activity Positively Responded to Interactive Effect of Nitrogen and Phosphorus in Young
Lipopolysaccharide Induces The Production Of Diagnostic Monoclonal Antibody By Hybridoma Cells Against Congenital Adrena
Towards the development of automated fed-batch cell culture processes at microscale.
Inhibition of apoptosis using exosomes in Chinese hamster ovary cell culture
Cysteine in cell culture media induces acidic IgG1 species by disrupting the disulfide bond network
Enhanced cell growth, production, and mAb quality produced in Chinese hamster ovary-K1 cells by supplementing polyamine
Alanyl‐Glutamine Attenuates Soybean Meal‐Induced Intestinal Dysfunction and Growth Retardation in Largemouth Bass (Micro
Modular development enables rapid design of media for alternative hosts
Potential of growth factors and steroid hormones from cell cultures to improve in vitro fertilization in bovine
Cellular and molecular outcomes of glutamine supplementation in the brain of succinic semialdehyde dehydrogenase-deficie
Overexpression and purification of HSV-2 glycoprotein D in suspension CHO cells with serum-free medium and immunogenicit
Combining Butyrated ManNAc with Glycoengineered CHO Cells Improves EPO Glycan Quality and Production.
Conformational Bias in 2'-Selenium-Modified Nucleosides and the Effect on Helical Structure and Extracellular Recom
Dietary Supplementation of L-Arginine and N-Carbamylglutamate Attenuated the Hepatic Inflammatory Response and Apoptosis
Comparative study of commercial media to improve GMP manufacturing of recombinant human interferon β-1a by CHO cells in
Strategies and Considerations for Improving Recombinant Antibody Production and Quality in Chinese Hamster Ovary Cells.
Viable cell density as an indicator for dynamic feeding strategy in fed-batch and perfusion CHO cell culture.
Effect of three probiotic Bacillus strains supplemented feeds on growth, carcass composition and blood parameters of Cla
Production of butyrate and branched-chain amino acid catabolic byproducts by CHO cells in fed-batch culture enhances the
Replacement of Isoleucine and Leucine by their Keto Acids leads to increased formation of α-Hydroxy Acids in Chinese Ham
Amino acid nutrition and chicken gut health
Evaluating the impact of media and feed combinations on CHO cell culture performance and monoclonal antibody (trastuzuma
Effect of dietary supplementation with apple cider vinegar and propionic acid on hemolymph chemistry, intestinal microbi
Methionine and Glycine Stabilize Mitochondrial Activity in Sake Yeast During Ethanol Fermentation
COMPREHENSIVE EVALUATION OF EXPRESSION PLATFORM: CHERRY PICKING THE ‘RIGHT’ TO ACCOMPLISH THE ‘BEST
Kinetic modeling: A tool for temperature shift and feeding optimization in cell culture process development.
A paternal diet for offspring success?
Enhanced antibody production in Chinese hamster ovary cell cultures supplemented with barley shochu distillation by-prod
High-throughput profiling of nucleotides and nucleotide sugars to evaluate their impact on antibody N-glycosylation.
Beyond tyrosine feeding: A novel fed-batch cultivation strategy based on tyrosine metabolic engineering in recombinant C
Polyamines Counteract Carbonate-Driven Proteasome Stalling in Alkaline Conditions
Kinetic modeling: A tool for temperature shift and feeding optimization in cell culture process development.
Establishment of a fully automated microtiter plate-based system for suspension cell culture and its application for enh
Protein overproduction alters exosome secretion in Chinese hamster ovary cells.
A case study: Correlation of the nutrient composition in Chinese Hamster Ovary cultures with cell growth, antibody titre
Optimization of medium with perfusion microbioreactors for high density CHO cell cultures at very low renewal rate aided
Regulatory Role, Mechanism, and Metabolic Profile of BIOTIN in Gene Expression
402 Awardee Talk - Efficiency of nutrient use in ruminants: Current understanding and emerging questions
Impact of media and antifoam selection on monoclonal antibody production and quality using a high throughput micro‐biore
Betaine Supplementation Into High-Carbohydrate Diets Improves Feed Efficiency and Liver Health of Megalobrama amblycepha
Smart feeding strategies: probiotic and phytochemical synergy improves silkworm growth and silk output
Optimizing monoclonal antibody biosimilar production via transfer and active learning for targeted quality profiles.
Novel Data-Driven Mechanistic Modeling of Untargeted Metabolome Data Reveals Feed Component Effects in CHO Cell Bioproce
Using chemical chaperones to increase recombinant human erythropoietin secretion in CHO cell line.
Amino acid feeding reduces ammonia production through rearrangement of metabolic fluxes in central carbon metabolism of
Degradation Products of Tryptophan in Cell Culture Media: Contribution to Color and Toxicity.
Аrginine – biological role, biosynthesis and whey consumption
A novel dynamic flux balance analysis for modeling CHO cell fed-batch cultures with pH and temperature shifts.
Completely noninvasive multi-analyte monitoring system for cell culture processes.
Enhancing and stabilizing monoclonal antibody production by Chinese hamster ovary (CHO) cells with optimized perfusion c
Characterization of soy protein hydrolysates and influence of its iron content on monoclonal antibody production by a mu
Nutrient supplementation strategy improves cell concentration and longevity, monoclonal antibody production and lactate
Process development for production of non-originator NISTmAb from CHO and NS0 cell lines.
Effects of a high cholesterol diet on chill tolerance are highly context-dependent in Drosophila.
Sestrin2 Negatively Regulates Casein Synthesis through the SH3BP4-mTORC1 Pathway in Response to AA Depletion or Suppleme
Concomitant reduction of lactate and ammonia accumulation in fed-batch cultures: Impact on glycoprotein production and q
Wheels turning: CHO cell modeling moves into a digital biomanufacturing era: Subtitle: CHO Metabolic Modeling.
Multi-Omics Study on the Impact of Cysteine Feed Level on Cell Viability and mAb Production in a CHO Bioprocess.
Intracellular response to process optimization and impact on productivity and product aggregates for a high-titer CHO ce
Bioprocess development for scalable production of cultivated meat
Effects of methionine and guanidinoacetic acid supplementation on performance and energy metabolites in breast muscle of
High-level production and purification of bioactive recombinant human activin A in Chinese hamster ovary cells
Modulation of growth performance, gut microflora, non-specific immunity and gene expression of proinflammatory cytokines
Xylanase supplementation of pelleted wheat-based diets increases growth efficiency and apparent metabolizable energy and
Generation and Characterization of Stable Redox-Reporter Mammalian Cell Lines of Biotechnological Relevance.
S-Sulfocysteine simplifies fed-batch processes and increases the CHO specific productivity via anti-oxidant activity.
Evaluation of Sorbitol-Methanol Co-Feeding Strategy on Production of Recombinant Human Growth Hormone in Pichia Pastoris
Leucine-Rich Diet Modulates the Metabolomic and Proteomic Profile of Skeletal Muscle during Cancer Cachexia
Effects of L-Histidine and Sodium Acetate on β-Casein Expression in Nutrient-Restricted Bovine Mammary Epithelial Cells
Modern feeding strategies for breeding boars.
Dietary Supplementation with Chromium DL-Methionine Enhances Growth Performance of African Catfish (Clarias gariepinus).
Adaptation of CHO cells in serum-free conditions for erythropoietin production: Application of EVOP technique for proces
Improving an intensified and integrated continuous bioprocess platform for biologics manufacturing.
Analysis of pasture supplementation strategies by means of a mechanistic model of ruminal digestion and metabolism in th
LC-MS/MS-based quantitative proteomic and phosphoproteomic analysis of CHO-K1 cells adapted to growth in glutamine-free
Increased MSX level improves biological productivity and production stability in multiple recombinant GS CHO cell lines.
Multi-omics analysis of Chinese hamster ovary cell-based biopharmaceutical production processes
Feeding practices and animal-level factors associated with daily milk yield in lactating smallholder dairy cows in Kiamb
Influence of media composition on recombinant monoclonal IgA1 glycosylation analysed by lectin-based protein microarray
Sequential active learning for medium optimization in mAb production.
Influence of growth factors and different supplements on metabolic response and productivity of IgA-producing CHO cell l
Partial Characterization of Yeast Hydrolysates for Insights on Chemically Defined Media for Sf-9 Insect Cells
Two scale‐down tools for the optimization of perfusion bioreactors for the manufacture of biopharmaceuticals
Advancing Raman model calibration for perfusion bioprocesses using spiked harvest libraries
Effect of Supplementing Lysine and Isoleucine as Limiting Amino Acids on Growth Performance and Amino Acid Deposition of
Phytase supplementation in sorghum-based diet enhances nutrient digestibility, energy utilization, and antioxidant statu
Modeling of cell cultivation for monoclonal antibody production processes considering lactate metabolic shifts.
Evaluation of Dietary Essential Amino Acid Supplementation on Growth, Digestive Capacity, Antioxidant, and Intestine Hea
Dietary Supplementation with Linseed Oil Ethyl Esters Improves Sexual Behavior and Chosen Seminal Parameters in Porcine
Effects of trehalose supplementation on the growth performance and intestinal innate immunity of juvenile chicks.
Modulating fatty acid metabolism and composition of CHO cells by feeding high levels of fatty acids complexed using meth
Intracellular response to process optimization and impact on productivity and product aggregates for a high‐titer CHO ce
Mammalian Cell Line Development Platform for Recombinant Protein Production: Expanding the Protein Expression Toolbox fo
Development of a serum free medium for HUMIRA <sup>®</sup> biosimilar by design of experiment approaches
Effect of cereal soaking and carbohydrase supplementation on growth, nutrient digestibility and intestinal microbiota in
Characterization of Yeast Protein Hydrolysate for Potential Application as a Feed Additive
The Effect of Branched Chain Amino Acid Supplementation on Stroke-Related Sarcopenia.
Effect of fermented heat-treated rice bran on performance and possible role of intestinal microbiota in laying hens.
Insights into the roles of exogenous phenylalanine and tyrosine in improving rapamycin production of Streptomyces rapamy
Applications and analysis of hydrolysates in animal cell culture
Modulating antibody N-glycosylation through feed additives using a multi-tiered approach
Selection of chemically defined media for CHO cell fed-batch culture processes
Mathematical model of the multi-amino acid multi-transporter system predicts uptake flux in CHO cells
Glycosylation Flux Analysis of Immunoglobulin G in Chinese Hamster Ovary Perfusion Cell Culture
Comparative Proteomics Analysis Reveals L-Arginine Activates Ethanol Degradation Pathways in HepG2 Cells
Debottlenecking and reformulating feed media for improved CHO cell growth and titer by data-driven and model-guided anal
Apparent nutrient digestibility of carbohydrate (corn) in Cirrhinus mrigala under the influence of chromium chloride hex
Pea Peptide Supplementation in Conjunction With Resistance Exercise Promotes Gains in Muscle Mass and Strength
Identification of Cell Culture Factors Influencing Afucosylation Levels in Monoclonal Antibodies by Partial Least-Square
Generating aldehyde-tagged antibodies with high titers and high formylglycine yields by supplementing culture media with
In Vitro Supplementation of Glycine Improves Quality of Cryopreserved Bull Semen
Improved Titer in Late-Stage Mammalian Cell Culture Manufacturing by Re-Cloning
Genome-scale modeling of Chinese hamster ovary cells by hybrid semi-parametric flux balance analysis
Dynamic Optimization of a Fed-Batch Nosiheptide Reactor
Application of high EPA-producing Mortierella alpina in laying hen feed for egg DHA accumulation.
Serum-free cultures of C2C12 cells show different muscle phenotypes which can be estimated by metabolic profiling
Tracking dipeptides at work-uptake and intracellular fate in CHO culture
Strategy for Developing a Stable CHO Cell Line that Produces Large Titers of Trastuzumab Antibody
Impact of fed-batch process intensification on the productivity and product quality of two CHO cell lines expressing uni
Effects of lysine and threonine on milk yield, amino acid metabolism, and fecal microbiota of Yili lactating mares
Clever Experimental Designs: Shortcuts for Better iPSC Differentiation
Effects of dietary resveratrol supplementation on digestive enzymes activities and serum biochemistry of rainbow trout (
Evaluation of Plant- and Microbial-Derived Protein Hydrolysates as Substitutes for Fetal Bovine Serum in Cultivated Seaf
Analysis of coagulation factor IX in bioreactor cell culture medium predicts yield and quality of the purified product
Effect of Saccharomyces cerevisiae Fermentation Product on Ruminal Fermentation, Blood Metabolites, and Milk Production
Proteomics Profiling of Chimeric-Truncated Tissue Plasminogen activator Producing- Chinese Hamster Ovary Cells Cultivate
Temporal Effects of Galactose and Manganese Supplementation on Monoclonal Antibody N-Linked Glycosylation in Fed-Batch a
Mechanistic insights into the biological activity of S-Sulfocysteine in CHO cells using a multi-omics approach
SWATH-MS insights on sodium butyrate effect on mAbs production and redox homeostasis in CHO cells
Human Sialidase Neu3 is S-Acylated and Behaves Like an Integral Membrane Protein
High glucose and low specific cell growth but not mild hypothermia improve specific r-protein productivity in chemostat
Evaluation and use of disaccharides as energy source in protein-free mammalian cell cultures
Stability and Requirement for Thiamin in a Cell Culture Feed Used to Produce New Biological Entities
Viable cell density as an indicator for dynamic feeding strategy in fed-batch and perfusion CHO cell culture.
Use of real-time cellular analysis and Plackett-Burman design to develop the serum-free media for PC-3 prostate cancer c
Optimizing the Production of gp145, an HIV-1 Envelope Glycoprotein Vaccine Candidate and Its Encapsulation in Guanosine
Metabolic characterization of a CHO cell size increase phase in fed-batch cultures.
The Effect of the Expression of the Antiapoptotic BHRF1 Gene on the Metabolic Behavior of a Hybridoma Cell Line
Development of M³C strategies in production processes with CHO cell cultures to prevent the formation of product aggrega
Dynamic Optimisation of Fed-Batch Bioreactors for mAbs: Sensitivity Analysis of Feed Nutrient Manipulation Profiles
Streamlined identification of strain engineering targets for bioprocess improvement using metabolic pathway enrichment a
Uridine modulates monoclonal antibody charge heterogeneity in Chinese hamster ovary cell fed-batch cultures
Experimental studies from shake flasks to 3 L stirred tank bioreactor of nutrients and oxygen supply conditions to impro
Enhanced l-Malic Acid Production by Aspergillus oryzae DSM 1863 Using Repeated-Batch Cultivation.
Addition of a histone deacetylase inhibitor increases recombinant protein expression in Medicago truncatula cell culture
Therapeutic Fc fusion protein misfolding: A three-phasic cultivation experimental design
A dynamic metabolic flux analysis (DMFA) model for performance predictions of diverse CHO cell culture process modes and
Stochastic biological system-of-systems modelling for iPSC culture
Dietary methionine supplementation during the estrous cycle improves follicular development and estrogen synthesis in ra
Dietary Taurine Improves The Growth Performance, Health Status and Liver Histopathology of Meagre (Argyrosomus Regius) F
Effects of dietary lysine levels on jejunal expression of amino
A CRISPR-HITI strategy approach to improve CHO cell viability by modifying the 3'UTR of Caspase 8 Associated Protei
Modular development enables rapid design of media for alternative hosts
A Guide to Transient Expression of Membrane Proteins in HEK-293 Cells for Functional Characterization
Desenvolvimento de anti-hTNF&#945; terapêutico.
Enzyme capacity-based genome scale modelling of CHO cells
Application of maltose as energy source in protein-free CHO-K1 culture to improve the production of recombinant monoclon
Bacillus subtilis Produces Amino Acids to Stimulate Protein Synthesis in Ruminal Tissue Explants via the Phosphatidylino
Ribosome profiling-guided depletion of an mRNA increases cell growth rate and protein secretion
Chinese Hamster Ovary Cell Line Development via Imaging Flow Cytometry and Directed Evolution
Enhanced recombinant protein production in CHO cell continuous cultures under growth-inhibiting conditions is associated
Discovery of l-threonine transaldolases for enhanced biosynthesis of beta-hydroxylated amino acids
Effect of Fe2+ and Mn2+ addition on growth and β-carotene production of Dunaliella salina
Enhancement of recombinant human IL-24 (rhIL-24) protein production from site-specific integrated engineered CHO cells b
Production Processes for Monoclonal Antibodies
Effects of dandelion (Taraxacum sp.,) supplements on lactation performance, antioxidative activity, and plasma metabolom
Development and qualification of a high-yield recombinant human Erythropoietin biosimilar
Regulation of amino acid transporters in the mammary gland from late pregnancy to peak lactation in the sow
Optimizing Bispecific Antibody Expression via Multi-Omics Analysis and Vector Redesign
Glutamine supplementation moderately affects growth, plasma metabolite and free amino acid patterns in neonatal low birt
The Epigenetic Regulation of Blinatumomab Gene Expression: Tumor Cell-dependent T cell Response against Lymphoma Cells a
Produção do fator VII da coagulação sanguínea recombinante em células humanas
Exploring metabolic effects of dipeptide feed media on CHO cell cultures by in silico model-guided flux analysis
Responses of CHO-DHFR cells to ratio of asparagine to glutamine in feed media: cell growth, antibody production, metabol
Employing active learning in the optimization of culture medium for mammalian cells
Dietary supplementation with free methionine or methionine dipeptide mitigates intestinal oxidative stress induced by Ei
Changes in the Intestine Microbial, Digestive, and Immune-Related Genes of Litopenaeus vannamei in Response to Dietary P
Strategies and Considerations for Improving Recombinant Antibody Production and Quality in Chinese Hamster Ovary Cells
Advances of Glycometabolism Engineering in Chinese Hamster Ovary Cells
Employing active learning in the optimization of culture medium for mammalian cells
Identification of Small Molecules Affecting the Secretion of Therapeutic Antibodies with the Retention Using Selective H
A dynamic pathway analysis approach reveals a limiting futile cycle in N-acetylglucosamine overproducing Bacillus subtil
Comparing Kinetic versus Stoichiometric Priorities in Hybrid Models of CHO Metabolism
A Beefy-R culture medium: replacing albumin with rapeseed protein isolates
Hybrid Modelling and Multi- Parametric Control of Bioprocesses
Dynamics of Amino Acid Metabolism, Gene Expression, and Circulomics in a Recombinant Chinese Hamster Ovary Cell Line Ada
Dietary Prebiotics and Probiotics Influence the Growth Performance, Feed Utilisation, and Body Indices of Snakehead (Cha
Levan Production in Shake Flask and Fermenter Influence of Feeding Strategy on Levan Yield and Molecular Weight Distribu
Culture media selection and feeding strategy for high titer production of a lentiviral vector by stable producer clones
High-Level Production of scFv-Fc Antibody Using an Artificial Promoter System with Transcriptional Positive Feedback Loo
Dietary Enteromorpha Polysaccharides Supplementation Improves Breast Muscle Yield and Is Associated With Modification of
Exploring the effectiveness of in ovo feeding of vitamin C based on the embryonic vitamin C synthesis and absorption in
Process transfer and optimization of Chinese hamster ovary cell cultivation for monoclonal antibody production
Over-expression of a Codon Optimized Yeast Cytosolic Pyruvate Carboxylase (PYC2) in CHO Cells for an Augmented Lactate M
Wheat gluten hydrolysates promotes fermentation performance of brewer’s yeast in very high gravity worts
Improved performance of a rainbow trout selected strain is associated with protein digestion rates and synchronization o
Dietary Aroclor 1254-Induced Toxicity on Antioxidant Capacity, Immunity and Energy Metabolism in Chinese Mitten Crab Eri
Biljni proteinski hidrolizati kao dodatak medijima za uzgoj životinjskih stanica
Boosting Productivity for Advanced Biomanufacturing by Re-Using Viable Cells
Cell-culture growth conditions resulting in the oxidation of a recombinant antigen-binding fragment
A control strategy to investigate the relationship between specific productivity and high-mannose glycoforms in CHO cell
Characterization and design of dipeptide media formulation for scalable therapeutic production.
Cold atmospheric plasma treatment enhances recombinant model protein production in yeast Pichia pastoris
Optimization and Scale-Up of Fermentation Processes Driven by Models
Identifying model error in metabolic flux analysis – a generalized least squares approach
Essentially leading antibody production: An investigation of amino acids, myeloma and natural V-region signal peptides i
Rich production media as a platform for CHO cell line development
Enhanced Production of Anti-PD1 Antibody in CHO Cells through Transient Co-Transfection with Anti-Apoptotic Gene Bcl-xL
Preclinical Immune Response and Safety Evaluation of the Protein Subunit Vaccine Nanocovax for COVID-19
Combination of strong anion exchange liquid chromatography with microchip capillary electrophoresis sodium dodecyl sulfa
Effect of different levels of protein concentrates supplementation on the growth performance, plasma amino acids profile
DataSheet_2_Preclinical Immune Response and Safety Evaluation of the Protein Subunit Vaccine Nanocovax for COVID-19.pdf
Model Transferability and Reduced Experimental Burden in Cell Culture Process Development Facilitated by Hybrid Modeling
Engineering of Chinese hamster ovary cells for co-overexpressing MYC and XBP1s increased cell proliferation and recombin
Explainable AI for CHO cell culture media optimization and prediction of critical quality attribute
Developing a medium combination to attain similar glycosylation profile to originator by DoE and cluster analysis method
Development of serum-free and grain-derived-nutrient-free medium using microalga-derived nutrients and mammalian cell-se
Metabolic Engineering of Saccharomyces cerevisiae for Heterologous Carnosic Acid Production
Ncl1-mediated metabolic rewiring critical during metabolic stress
Glycosylation flux analysis reveals dynamic changes of intracellular glycosylation flux distribution in Chinese hamster
Supplementing dairy feed by dicalcium phosphate and effect on dry matter intake, digestibility, milk composition, and bl
Mild hypothermia upregulates myc and xbp1s expression and improves anti-TNFα production in CHO cells
Inferring secretory and metabolic pathway activity from omic data with secCellFie
Sodium acetate increases the productivity of HEK293 cells expressing the ECD-Her1 protein in batch cultures: experimenta
Amino Acid Requirements of the Chinese Hamster Ovary Cell Metabolism during Recombinant Protein Production
Compartment-specific metabolome labeling enables the identification of subcellular fluxes that may serve as promising me
Stable isotopes in tissues discriminate the diet of free-living wild boar from different areas of central Italy.
Is the development of low-cost media one of the greatest challenges to produce cultivated meat on an industrial scale?
Roles and mechanisms of methionine on milk productivity of dairy cows
Inositol depletion regulates phospholipid metabolism and activates stress signaling in HEK293T cells
Rich production media as a platform for CHO cell line development
Coagulation factor IX analysis in bioreactor cell culture supernatant predicts quality of the purified product
Fast and long-lasting immune response to S-trimer COVID-19 vaccine adjuvanted by PIKA
Functional Trimeric SARS-CoV-2 Envelope Protein Expressed in Stable CHO Cells
Evaluating the impact of media and feed combinations on CHO cell culture performance and monoclonal antibody (trastuzuma
Availability of Amino Acids Extends Chronological Lifespan by Suppressing Hyper-Acidification of the Environment in Sacc
Ouantitative Proteomic Analysis of Cellular Responses to a Designed Amino Acid Feed in a Monoclonal Antibody Producing C
Harnessing secretory pathway differences between HEK293 and CHO to rescue production of difficult to express proteins
Impact of Acetylated and Non-Acetylated Fucose Analogues on IgG Glycosylation
High extracellular lactate increases reductive carboxylation in breast tissue cell lines grown under normoxic conditions
Supply of methionine and arginine alters phosphorylation of mechanistic target of rapamycin (mTOR), circadian clock prot
Comparative study on the effects of crystalline L-methionine and methionine hydroxy analogue calcium supplementations in
Key Challenges in Designing CHO Chassis Platforms
Critical Analysis of the Commercial Potential of Plants for the Production of Recombinant Proteins
Lysine and Leucine Deficiencies Affect Myocytes Development and IGF Signaling in Gilthead Sea Bream (Sparus aurata)
Deciphering Metabolic Pathways in High Seeding Density Fed-Batch Processes for Monoclonal Antibody Production: A Computa
Genetics, environmental stress, and amino acid supplementation affect lactational performance via mTOR signaling pathway
Evaluating the potential of marine invertebrate and insect protein hydrolysates to reduce fetal bovine serum in cell cul
Implementation of Design of Experiments (DOE) for Optimization of Feeding Strategy and Glyco-Engineering of Trastuzumab
N-Glycosylation modulators for targeted manipulation of glycosylation for monoclonal antibodies
Fed-Batch Fermentation of L- Threonine by Escherichia Coli Supplemented with B-Vitamins
Bigdata analytics identifies metabolic inhibitors and promoters for productivity improvement and optimization of monoclo
Effect of dietary selenium on postprandial protein deposition in the muscle of juvenile rainbow trout (Oncorhynchus myki
Model-assisted DoE software: optimization of growth and biocatalysis in Saccharomyces cerevisiae bioprocesses
Fast exchange fluxes around the pyruvate node: a leaky cell model to explain the gain and loss of unlabelled and labelle
Amino acids in the cultivation of mammalian cells
Fermented Goat Milk Supplementation in Rats Hypercholesterolmic on Malonyldialdehyde and Description of Liver Histopatho
Supplementing L-Isoleucine Increases Medium Protein and Alters the Expression of Genes and Proteins Involved in Milk Pro
Abstracts from the 26th European Society for Animal Cell Technology Meeting - Cell culture technologies: bridging academ
A guide to 13C metabolic flux analysis for the cancer biologist
mAb Production Modeling and Design Space Evaluation Including Glycosylation Process
Regulation of urea cycle related enzymes in response to freezing in the wood frog, Rana sylvatica
Protein evaluation in fish: African catfish as a case study
Temperature Upshifts in Mammalian Cell Culture: A Suitable Strategy for Biosimilar Monoclonal Antibodies?
Evidence for co-translational misincorporation of non-canonical amino acid hydroxyproline in recombinant antibodies prod
Marked variations in gut microbiota and some innate immune responses of fresh water crayfish, marron (Cherax cainii, Aus
Effects of dietary supplementation with histidine and β-alanine on blood plasma metabolome of broiler chickens at differ
Effect of dietary tryptophan supplementation on growth, body composition and digestive enzymes activity of juvenile silv
Varying the ratio of Lys: Met through enhancing methionine supplementation improved milk secretion ability through regul
Genome-scale reconstructions of the mammalian secretory pathway predict metabolic costs and limitations of protein secre
Supplementing D-Type and L-Type Methionine and Its Precursor Alters the Expression of mRNA, Proteins and Metabolites Inv
Stable high-level expression of factor VIII in Chinese hamster ovary cells in improved elongation factor-1 alpha-based s
Multi-omic characterization of antibody-producing CHO cell lines elucidates metabolic reprogramming and nutrient uptake
The Reproduction Rate of Peptide Transporter PEPT-1 Deficient C. elegans Is Dependent on Dietary Glutamate Supply.
Cultivated meat: recent technological developments, current market and future challenges
Maltose-Binding Protein (MBP), a Secretion-Enhancing Tag for Mammalian Protein Expression Systems
Effects of Dietary Inclusion of Shrimp Paste on Growth Performance, Digestive Enzymes Activities, Antioxidant and Immuno
Effect of Sialic Acid on Mammalian Cell Culture and Protein Expression: A Potential Productivity Enhancer for Biopharmac
Dynamic genome-scale metabolic modeling of the yeast Pichia pastoris
Characterization and optimization of mnn11Δ-mediated enhancement in heterologous protein production in Kluyveromyces mar
Comparison of secretory signal peptides for heterologous protein expression in microalgae: Expanding the secretion portf
Enhancing the productivity and proliferation of CHO-K1 cells by oncoprotein YAP (Yes-associated protein)
Optimization of transient protein production by chemically transfected CHO suspension cells
Engineered autocrine signaling eliminates muscle cell FGF2 requirements for cultured meat production
Challenges and Emerging Technologies in Biomanufacturing of Monoclonal Antibodies (mAbs)
Protein-specific signal peptides for mammalian vector engineering
Abstracts from the 25th European Society for Animal Cell Technology Meeting: Cell Technologies for Innovative Therapies
Development of a scalable single process for producing SARS-CoV-2 RBD monomer and dimer vaccine antigens
Research progress in the role and mechanism of Leucine in regulating animal growth and development
Metabolic engineering of CHO cells for the development of a robust protein production platform
The effect of the chemical chaperone 4-phenylbutyrate on secretion and activity of the p.Q160R missense variant of coagu
Identification of process-relevant kinases in human amniotic production cells
Advancements in CHO metabolomics: techniques, current state and evolving methodologies
A metabolic network-based approach for developing feeding strategies for CHO cells to increase monoclonal antibody produ
Use of different concentrations of enzymesporin probiotic in feeding of growing young pigs
Thermodynamic limitations of metabolic strategies for PHB production from formate and fructose in <i>Cupriavidus necator
alimohsin@ecust.edu.cn
Continuous Feeding Reduces the Generation of Metabolic Byproducts and Increases Antibodies Expression in Chinese Hamster
ilyichev@vector.nsc.ru
Immunogenic and Protective Properties of Recombinant Hemagglutinin of Influenza A (H5N8) Virus
nlewisres@ucsd.edu
A genome-scale metabolic network model synergizes with statistical learning to predict amino acid concentrations in Chin